Publications

Oncogene

A genome-wide CRISPR screen in human prostate cancer cells reveals drivers of macrophage-mediated cell killing and positions AR as a tumor-intrinsic immunomodulator.

28-07-2026

Cancer chemotherapy and pharmacology

The use of pharmacodynamic results for recommended phase II decision making in oncology clinical trials.

06-07-2026

Cancer discovery

Germline CDK12 variants in aggressive prostate cancer.

02-07-2026

Blood

DOT1L Shapes ncPRC1-Target Gene Repression to Maintain Germinal Center B Cell Identity of Diffuse Large B cell Lymphoma.

29-05-2026

European urology oncology

Cabazitaxel Versus Abiraterone or Enzalutamide for Poor-prognosis Metastatic Castration-resistant Prostate Cancer After Docetaxel: A Phase 2 Trial with a Circulating Tumor DNA Analysis.

01-04-2026

Nature

Regulatory grammar in human promoters uncovered by MPRA-based deep learning.

01-03-2026

Annals of oncology : official journal of the European Society for Medical Oncology

Repertoire and clinical hierarchy of AR locus alterations in castration-resistant prostate cancer.

01-03-2026

NAR genomics and bioinformatics

DEprot: a comprehensive R-package for the analysis of label-free quantitation mass spectrometry data.

01-03-2026

Cancer discovery

Mind the GARP: How Glucocorticoids Unleash T Cells against Melanoma.

06-02-2026

Nature

Fasting boosts breast cancer therapy efficacy via glucocorticoid activation.

01-01-2026

Proceedings of the National Academy of Sciences of the United States of America

Distinct transcription factor interactions drive HOXB13 activity in different stages of prostate cancer.

09-12-2025

Proceedings of the National Academy of Sciences of the United States of America

p53 regulates the expression of histone modifiers to restrict stemness and maintain differentiated luminal identity in breast cancer.

04-11-2025

Cancer discovery

Germline-Somatic Liaison Dictates Cancer Subtypes via de novo Steroid Biosynthesis.

06-10-2025

iScience

A 3D genome compendium of breast cancer progression.

19-09-2025

Nature genetics

Tamoxifen induces PI3K activation in uterine cancer.

01-09-2025

Proceedings of the National Academy of Sciences of the United States of America

TRIM24 as a therapeutic target in endocrine treatment-resistant breast cancer.

19-08-2025

bioRxiv : the preprint server for biology

Genetic and Epigenetic Reprogramming of Transposable Elements Drives ecDNA-Mediated Metastatic Prostate Cancer.

12-08-2025

Trends in molecular medicine

The emerging regulatory interface between DNA repair and steroid hormone receptors in cancer.

01-08-2025

Cell reports. Medicine

Epigenetic profiling identifies markers of endocrine resistance and therapeutic options for metastatic castration-resistant prostate cancer.

15-07-2025

Communications biology

TRIM33 loss reduces androgen receptor transcriptional output and H2BK120 ubiquitination.

11-07-2025

Science (New York, N.Y.)

Zincore, an atypical coregulator, binds zinc finger transcription factors to control gene expression.

03-07-2025

Genome research

Comprehensive functional annotation of ESR1-driven enhancers in breast cancer reveals hierarchical activity independent of genomic and epigenomic contexts.

01-07-2025

Genome biology

Endometrial tumorigenesis involves epigenetic plasticity demarcating non-coding somatic mutations and 3D-genome alterations.

09-05-2025

Cell reports

SRBD1, a highly conserved gene required for chromosome individualization.

22-04-2025

Genome medicine

Whole genome sequencing of 378 prostate cancer metastases reveals tissue selectivity for mismatch deficiency with potential therapeutic implications.

20-03-2025

BJS open

Perineal wound complications after total neoadjuvant therapy or chemoradiotherapy followed by abdominoperineal excision in patients with high-risk locally advanced rectal cancer in the RAPIDO trial.

04-03-2025

Cancer discovery

Androgen Receptor Inhibition Increases MHC Class I Expression and Improves Immune Response in Prostate Cancer.

03-03-2025

Proceedings of the National Academy of Sciences of the United States of America

Comparative transcriptomics reveals a mixed basal, club, and hillock epithelial cell identity in castration-resistant prostate cancer.

11-02-2025

The Journal of clinical investigation

Low tristetraprolin expression activates phenotypic plasticity and primes transition to lethal prostate cancer in mice.

19-11-2024

Nucleic acids research

Chromatin context-dependent effects of epigenetic drugs on CRISPR-Cas9 editing.

27-08-2024

The Journal of clinical investigation

Genomic and transcriptomic features of androgen receptor signaling inhibitor resistance in metastatic castration-resistant prostate cancer.

13-08-2024

Nature genetics

Integrated analyses highlight interactions between the three-dimensional genome and DNA, RNA and epigenomic alterations in metastatic prostate cancer.

01-08-2024

Journal of experimental & clinical cancer research : CR

Emerging frontiers in androgen receptor research for prostate Cancer: insights from the 2nd international androgen receptor Symposium.

17-07-2024

BMC medical genomics

Co-expression in tissue-specific gene networks links genes in cancer-susceptibility loci to known somatic driver genes.

15-07-2024

FEBS letters

Nuclear receptor Nur77 and Yin-Yang 1 synergistically increase mitochondrial abundance and activity in macrophages.

01-07-2024

Cancer discovery

Cancer Core Europe: Leveraging Institutional Synergies to Advance Oncology Research and Care Globally.

01-07-2024

European journal of cancer (Oxford, England : 1990)

Oncological outcomes after a pathological complete response following total neoadjuvant therapy or chemoradiotherapy for high-risk locally advanced rectal cancer in the RAPIDO trial.

01-06-2024

Genome research

Estrogen receptor 1 chromatin profiling in human breast tumors reveals high inter-patient heterogeneity with enrichment of risk SNPs and enhancer activity at most-conserved regions.

15-05-2024

Clinical genitourinary cancer

Combined Cabazitaxel and Carboplatin Treatment of Metastatic Castration Resistant Prostate Cancer Patients, With Innate or Acquired Resistance to Cabazitaxel Monotherapy.

01-04-2024

NPJ systems biology and applications

Agent-based modeling of the prostate tumor microenvironment uncovers spatial tumor growth constraints and immunomodulatory properties.

21-02-2024

Cancers

It Takes Two to Tango: The Interplay between Prostate Cancer and Its Microenvironment from an Epigenetic Perspective.

10-01-2024

Molecular oncology

Proteomics on malignant pleural effusions reveals ERα loss in metastatic breast cancer associates with SGK1-NDRG1 deregulation.

01-01-2024

EMBO molecular medicine

Luminal breast cancer identity is determined by loss of glucocorticoid receptor activity.

07-12-2023

Life science alliance

TRIM25 targets p300 for degradation.

01-12-2023

ESMO open

Corrigendum to "Authors' reply-Does the RAPIDO trial suggest a benefit of post-operative chemotherapy after preoperative chemoradiation in rectal cancer? No, it does not": [ESMO Open 8 (2023) 101645].

01-12-2023

Nucleic acids research

Compartmentalization of androgen receptors at endogenous genes in living cells.

10-11-2023

Cancer discovery

Transposable Elements Are Co-opted as Oncogenic Regulatory Elements by Lineage-Specific Transcription Factors in Prostate Cancer.

01-11-2023

European urology

Grade Group 1 Prostate Cancers Exhibit Tumor-defining Androgen Receptor-driven Programs.

01-11-2023

Cell reports

Perturbations in 3D genome organization can promote acquired drug resistance.

31-10-2023

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Inhibiting the Glucocorticoid Receptor to Enhance Chemotherapy Response.

20-10-2023

A genome-wide CRISPR screen in human prostate cancer cells reveals drivers of macrophage-mediated cell killing and positions AR as a tumor-intrinsic immunomodulator.

The use of pharmacodynamic results for recommended phase II decision making in oncology clinical trials.

Germline CDK12 variants in aggressive prostate cancer.

DOT1L Shapes ncPRC1-Target Gene Repression to Maintain Germinal Center B Cell Identity of Diffuse Large B cell Lymphoma.

Cabazitaxel Versus Abiraterone or Enzalutamide for Poor-prognosis Metastatic Castration-resistant Prostate Cancer After Docetaxel: A Phase 2 Trial with a Circulating Tumor DNA Analysis.

Regulatory grammar in human promoters uncovered by MPRA-based deep learning.

Repertoire and clinical hierarchy of AR locus alterations in castration-resistant prostate cancer.

DEprot: a comprehensive R-package for the analysis of label-free quantitation mass spectrometry data.

Mind the GARP: How Glucocorticoids Unleash T Cells against Melanoma.

Fasting boosts breast cancer therapy efficacy via glucocorticoid activation.

Distinct transcription factor interactions drive HOXB13 activity in different stages of prostate cancer.

p53 regulates the expression of histone modifiers to restrict stemness and maintain differentiated luminal identity in breast cancer.

Germline-Somatic Liaison Dictates Cancer Subtypes via de novo Steroid Biosynthesis.

A 3D genome compendium of breast cancer progression.

Tamoxifen induces PI3K activation in uterine cancer.

TRIM24 as a therapeutic target in endocrine treatment-resistant breast cancer.

Genetic and Epigenetic Reprogramming of Transposable Elements Drives ecDNA-Mediated Metastatic Prostate Cancer.

The emerging regulatory interface between DNA repair and steroid hormone receptors in cancer.

Epigenetic profiling identifies markers of endocrine resistance and therapeutic options for metastatic castration-resistant prostate cancer.

TRIM33 loss reduces androgen receptor transcriptional output and H2BK120 ubiquitination.

Zincore, an atypical coregulator, binds zinc finger transcription factors to control gene expression.

Comprehensive functional annotation of ESR1-driven enhancers in breast cancer reveals hierarchical activity independent of genomic and epigenomic contexts.

Endometrial tumorigenesis involves epigenetic plasticity demarcating non-coding somatic mutations and 3D-genome alterations.

SRBD1, a highly conserved gene required for chromosome individualization.

Whole genome sequencing of 378 prostate cancer metastases reveals tissue selectivity for mismatch deficiency with potential therapeutic implications.

Perineal wound complications after total neoadjuvant therapy or chemoradiotherapy followed by abdominoperineal excision in patients with high-risk locally advanced rectal cancer in the RAPIDO trial.

Androgen Receptor Inhibition Increases MHC Class I Expression and Improves Immune Response in Prostate Cancer.

Comparative transcriptomics reveals a mixed basal, club, and hillock epithelial cell identity in castration-resistant prostate cancer.

Low tristetraprolin expression activates phenotypic plasticity and primes transition to lethal prostate cancer in mice.

Chromatin context-dependent effects of epigenetic drugs on CRISPR-Cas9 editing.

Genomic and transcriptomic features of androgen receptor signaling inhibitor resistance in metastatic castration-resistant prostate cancer.

Integrated analyses highlight interactions between the three-dimensional genome and DNA, RNA and epigenomic alterations in metastatic prostate cancer.

Emerging frontiers in androgen receptor research for prostate Cancer: insights from the 2nd international androgen receptor Symposium.

Co-expression in tissue-specific gene networks links genes in cancer-susceptibility loci to known somatic driver genes.

Nuclear receptor Nur77 and Yin-Yang 1 synergistically increase mitochondrial abundance and activity in macrophages.

Cancer Core Europe: Leveraging Institutional Synergies to Advance Oncology Research and Care Globally.

Oncological outcomes after a pathological complete response following total neoadjuvant therapy or chemoradiotherapy for high-risk locally advanced rectal cancer in the RAPIDO trial.

Estrogen receptor 1 chromatin profiling in human breast tumors reveals high inter-patient heterogeneity with enrichment of risk SNPs and enhancer activity at most-conserved regions.

Combined Cabazitaxel and Carboplatin Treatment of Metastatic Castration Resistant Prostate Cancer Patients, With Innate or Acquired Resistance to Cabazitaxel Monotherapy.

Agent-based modeling of the prostate tumor microenvironment uncovers spatial tumor growth constraints and immunomodulatory properties.

It Takes Two to Tango: The Interplay between Prostate Cancer and Its Microenvironment from an Epigenetic Perspective.

Proteomics on malignant pleural effusions reveals ERα loss in metastatic breast cancer associates with SGK1-NDRG1 deregulation.

Luminal breast cancer identity is determined by loss of glucocorticoid receptor activity.

TRIM25 targets p300 for degradation.

Corrigendum to "Authors' reply-Does the RAPIDO trial suggest a benefit of post-operative chemotherapy after preoperative chemoradiation in rectal cancer? No, it does not": [ESMO Open 8 (2023) 101645].

Compartmentalization of androgen receptors at endogenous genes in living cells.

Transposable Elements Are Co-opted as Oncogenic Regulatory Elements by Lineage-Specific Transcription Factors in Prostate Cancer.

Grade Group 1 Prostate Cancers Exhibit Tumor-defining Androgen Receptor-driven Programs.

Perturbations in 3D genome organization can promote acquired drug resistance.

Inhibiting the Glucocorticoid Receptor to Enhance Chemotherapy Response.

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