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Publications

Jos Beijnen Reset all filters

Results found: 1086

Showing results: 751 - 800

European journal of clinical pharmacology

Screening for polymorphisms in the PXR gene in a Dutch population.

01-05-2006

Trends in pharmacological sciences

Clinical proteomics: searching for better tumour markers with SELDI-TOF mass spectrometry.

01-05-2006

Analytical chemistry

Quantification of farnesylmethylcysteine in lysates of peripheral blood mononuclear cells using liquid chromatography coupled with electrospray tandem mass spectrometry: pharmacodynamic assay for farnesyl transferase inhibitors.

15-04-2006

World journal of gastroenterology

Identification of serum proteins discriminating colorectal cancer patients and healthy controls using surface-enhanced laser desorption ionisation-time of flight mass spectrometry.

14-03-2006

Clinical pharmacokinetics

Genetic polymorphisms of drug-metabolising enzymes and drug transporters in the chemotherapeutic treatment of cancer.

03-03-2006

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Relationship between cisplatin administration and the development of ototoxicity.

20-02-2006

Biomedical chromatography : BMC

A rapid and simple HPLC-UV method for the determination of inhibition characteristics of farnesyl transferase inhibitors.

01-02-2006

Clinical pharmacokinetics

Mass balance studies, with a focus on anticancer drugs.

25-01-2006

Biomedical chromatography : BMC

A simple and sensitive assay for the quantitative analysis of paclitaxel and metabolites in human plasma using liquid chromatography/tandem mass spectrometry.

01-01-2006

Die Pharmazie

Compatibility and stability of the novel anticancer agent ES-285 x HCl formulated with 2-hydroxypropyl-beta-cyclodextrin in infusion devices.

01-01-2006

Trends in pharmacological sciences

Use of P-glycoprotein and BCRP inhibitors to improve oral bioavailability and CNS penetration of anticancer drugs.

01-01-2006

Therapeutic drug monitoring

Population pharmacokinetics of cyclophosphamide and its metabolites 4-hydroxycyclophosphamide, 2-dechloroethylcyclophosphamide, and phosphoramide mustard in a high-dose combination with Thiotepa and Carboplatin.

01-12-2005

PDA journal of pharmaceutical science and technology

Pharmaceutical development of a parenteral lyophilised dosage form for the novel anticancer agent C1311.

01-12-2005

British journal of cancer

Phase I and pharmacological study of the farnesyltransferase inhibitor tipifarnib (Zarnestra, R115777) in combination with gemcitabine and cisplatin in patients with advanced solid tumours.

28-11-2005

Rapid communications in mass spectrometry : RCM

Simultaneous quantification of fludarabine and cyclophosphamide in human plasma by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry.

16-11-2005

Clinical pharmacokinetics

Clinical pharmacokinetics of cyclophosphamide.

20-10-2005

PDA journal of pharmaceutical science and technology

Pharmaceutical development of a parenteral lyophilised formulation of the investigational anticancer agent ES-285.HCl.

13-10-2005

Anti-cancer drugs

Phase I clinical and pharmacologic study of a 2-weekly administration of cisplatin and gemcitabine in patients with advanced non-small cell lung cancer.

01-10-2005

Cancer investigation

Modulation of oral drug bioavailability: from preclinical mechanism to therapeutic application.

01-10-2005

Cancer chemotherapy and pharmacology

Aprepitant inhibits cyclophosphamide bioactivation and thiotepa metabolism.

01-10-2005

Investigational new drugs

Trabectedin (Yondelis, formerly ET-743), a mass balance study in patients with advanced cancer.

01-10-2005

International journal of cancer

MRP2 (ABCC2) transports taxanes and confers paclitaxel resistance and both processes are stimulated by probenecid.

20-09-2005

Journal of pharmaceutical and biomedical analysis

Development and validation of an LC-UV method for the quantification and purity determination of the novel anticancer agent C1311 and its pharmaceutical dosage form.

01-09-2005

The oncologist

Current knowledge and future directions of the selective epidermal growth factor receptor inhibitors erlotinib (Tarceva) and gefitinib (Iressa).

01-09-2005

Cancer chemotherapy and pharmacology

Metabolism of docetaxel in mice.

01-09-2005

The oncologist

Development of farnesyl transferase inhibitors: a review.

01-09-2005

Analytical and bioanalytical chemistry

Determination of oxaliplatin in human plasma and plasma ultrafiltrate by graphite-furnace atomic-absorption spectrometry.

01-08-2005

Investigational new drugs

Human metabolism of [(14)C]indisulam following i.v. infusion in cancer patients.

01-08-2005

Anti-cancer drugs

Compatibility and stability of Imexon in infusion devices and its in vitro biocompatibility.

01-08-2005

Journal of pharmaceutical and biomedical analysis

LC-UV method development and validation for the investigational anticancer agent imexon and identification of its degradation products.

15-07-2005

Rapid communications in mass spectrometry : RCM

Quantitative analysis of the farnesyl transferase inhibitor lonafarnib (Sarasartrade mark, SCH66336) in human plasma using high-performance liquid chromatography coupled with tandem mass spectrometry.

05-07-2005

Drug metabolism and disposition: the biological fate of chemicals

Midazolam and cyclosporin a metabolism in transgenic mice with liver-specific expression of human CYP3A4.

01-07-2005

Investigational new drugs

Semi-physiological model describing the hematological toxicity of the anti-cancer agent indisulam.

01-06-2005

Therapeutic drug monitoring

Sparse sampling design for therapeutic drug monitoring of sequentially administered cyclophosphamide, thiotepa, and carboplatin (CTC).

01-06-2005

Biomedical chromatography : BMC

Quantitative analysis of docetaxel in human plasma using liquid chromatography coupled with tandem mass spectrometry.

01-06-2005

Proceedings of the National Academy of Sciences of the United States of America

Mice lacking multidrug resistance protein 3 show altered morphine pharmacokinetics and morphine-6-glucuronide antinociception.

17-05-2005

Cancer chemotherapy and pharmacology

Pharmacokinetics of low-dose doxorubicin and metabolites in patients with AIDS-related Kaposi sarcoma.

01-05-2005

Journal of pharmaceutical sciences

Pharmaceutical development of a lyophilised dosage form for the investigational anticancer agent Imexon using dimethyl sulfoxide as solubilising and stabilising agent.

01-05-2005

Cancer chemotherapy and pharmacology

Significant induction of cyclophosphamide and thiotepa metabolism by phenytoin.

01-05-2005

Pharmacological research

Hepatotoxicity and metabolism of trabectedin: a literature review.

01-05-2005

American journal of pharmacogenomics : genomics-related research in drug development and clinical practice

Detection of single nucleotide polymorphisms in the ABCG2 gene in a Dutch population.

09-04-2005

Anti-cancer drugs

Effects of co-medicated drugs on cyclophosphamide bioactivation in human liver microsomes.

01-03-2005

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

Compatibility and stability of the novel anti-cancer agent C1311 in infusion devices and its in vitro biocompatibility.

01-03-2005

Cancer chemotherapy and pharmacology

Phase I study of an oral formulation of irinotecan administered daily for 14 days every 3 weeks in patients with advanced solid tumours.

01-03-2005

British journal of clinical pharmacology

Population pharmacokinetics of orally administered paclitaxel formulated in Cremophor EL.

01-03-2005

Clinical cancer research : an official journal of the American Association for Cancer Research

Phase I clinical and pharmacokinetic study of kahalalide F in patients with advanced androgen refractory prostate cancer.

01-03-2005

Clinical pharmacokinetics

Individualised cancer chemotherapy: strategies and performance of prospective studies on therapeutic drug monitoring with dose adaptation: a review.

20-01-2005

Rapid communications in mass spectrometry : RCM

Stable isotopically labeled internal standards in quantitative bioanalysis using liquid chromatography/mass spectrometry: necessity or not?

13-01-2005

Cancer chemotherapy and pharmacology

Oral bioavailability of docetaxel in combination with OC144-093 (ONT-093).

01-01-2005

Mass spectrometry reviews

Liquid chromatography-mass spectrometry for the quantitative bioanalysis of anticancer drugs.

16-12-2004
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