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Emile Voest Group

Emile Voest

Host responses and personalized medicine

There are two areas of interest of my group: Genomics-guided precision medicine and precision medicine guided by tumor organoids.

To perform impactful research my group consists of a multidisciplinary, international team of biologists, computational scientists and clinicians.

More about this group

Our research

Precision Medicine

Our resources

Tumor organoids

Team members

Emile Voest
Emile Voest Group leader
Agnes Swiatkowska
Agnes Andres (Swiatkowska) Technician
Thomas Battaglia
Thomas Battaglia PhD student
Joyce Catsman
Joyce Catsman Technician
Krijn Dijkstra
Krijn Dijkstra Postdoctoral fellow
544922 Foskolos (1)
Theodoros Foskolos Bioinformatician
Pasfoto Soemeya
Soemeya Haj Mohammad PhD student
MARIJE KUIKEN Cropped
Marije Kuiken PhD student
Lindsay Leek
Lindsay Leek PhD student
Minh Chau Luong Boi
Minh Chau Luong Boi Technician
Iris Mimpen
Iris Mimpen PhD student
Miguel Parra Martinez
Miguel Parra Martinez Bioinformatician
Catherine Toner-Bartelds
Catherine Toner-Bartelds PhD student
Joris Van De Haar
Joris van de Haar Postdoctoral fellow
Maud van Maren
Maud van Maren PhD student
Allard Van Renterghem
Allard van Renterghem PhD student
Paula van Royen
Paula van Royen PhD student
Floor Verbeek
Floor Verbeek PhD student
Karlijn Verkerk
Karlijn Verkerk PhD student
Maartje Witsen
Maartje Witsen PhD student
+ 1
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Highlights of this group

VOESTGROEP

Newest additions to the group, Marije and Theo share their experiences

What's it like to be a member of the Voest Group?

Two new additions to the group, Marije and Theo, share their experiences.

 

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The Annual DRUP symposium

DRUP Museum

The annual DRUP symposium took place in the Central Museum in Utrecht on 11 November 2024

In the DRUP trial, patients with metastatic cancer who have exhausted all treatment options are given treatments based on genetic faults found in their tumor's DNA. Instead of traditional therapies, patients receive existing drugs that are already approved for other cancers sharing similar DNA abnormalities. This approach allows for a personalized treatment strategy, offering hope when conventional treatments have failed. 

 

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DRUP Website 550X320

European collaboration with DRUP-like clinical trials

In 2023, two European projects were launched: PCM4EU (Personalized Cancer Medicine for all EU citizens), funded by the EU4Health program as part of Europe’s Beating Cancer Plan (grant: 101079984) and PRIME-ROSE (Precision Cancer Medicine Repurposing System Using Pragmatic Clinical Trials), funded under the Horizon Europe program (grant: 101104269).

 

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Krijn Dijkstra square

NWO-XS funding award Krijn Dijkstra

Dr Krijn Dijkstra has been awarded funding through the NWO-XS Open Competition (2023-4) for an innovative project titled “One for all, all for one: do cancer cells cooperate to fight off T-cells?”

 

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DRUP Patient Impact Award Symposium

DRUP Patient Impact Award symposium

The DRUP Patient Impact Award symposium on 28 November 2023 featured contributions on the progress, collaboration and future plans of the DRUP study.

A globally unique clinical trial that offers treatment to small groups of patients with metastatic cancer for whom no more treatments are available and with a - for their cancer type - rare tumour DNA.

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Patient Impact Award 2022 groep DRUP

DRUP trial wins Patient Impact Award 2022

This year’s Patient Impact Award, the NKI’s annual prize for the most impactful clinical innovation, was awarded to the DRUP trial team. In this trial, patients with metastatic cancer who no longer have treatment options available to them are treated with medicines that have already been on the market for other tumor types.

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Joris Van De Haar

NVMO dissertation prizes awarded

Dr. Myriam Chalabi and Dr. Joris van de Haar are the winners of the oncology thesis awards.

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Science Retreat 2022

Newest additions to the group Maartje and Karlijn share their experiences

What's it like to be a member of the Voest Group? Two new additions to the group, Maartje and Karlijn, share their experiences.

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News and stories from this group

Organoids
Cancer cells inside a tumor respond differently to immunotherapy
09-07-2025
Battaglia Fig1a
Bacteria in cancer unmasked
09-04-2024
Drup Symp 20231128 23
Recap of the DRUP symposium
15-12-2023
Veni Subsidies, Veldman En Dijkstra
Improving and innovating immunotherapy: Veni grants stimulate innovative research
03-08-2023

Recent publications

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Our lab has recently published a number of papers, ranging from the relationship between the tumor microbiome and cancer metastasis, through the value of real-world data in oncology to the use of whole genome sequencing to discover biomarkers for immunotherapy. See some highlights of this exciting work below!

 

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Publications of this group

Nature

γδ T cells are effectors of immunotherapy in cancers with HLA class I defects.

01-01-2023
Key Publication
Nature

The Drug Rediscovery protocol facilitates the expanded use of existing anticancer drugs.

01-10-2019
Key Publication
More publications

More about our collaborations

Lodewyk Wessels Group
Computational biology Lodewyk Wessels

Treatment response in model systems & patients.
Ton Schumacher Group
Cancer immunology Ton Schumacher

T cell recognition of cancer tissue.

Contact our group

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Marlies van Bodegraven Personal Assistant
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