Publications

Breast cancer research and treatment

The 70-gene signature as a response predictor for neoadjuvant chemotherapy in breast cancer.

Breast (Edinburgh, Scotland)

Factors contributing to improved local control after mastectomy in patients with breast cancer aged 40 years or younger.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

First clinical experience with a multiple region of interest registration and correction method in radiotherapy of head-and-neck cancer patients.

European journal of epidemiology

Reliability of self-reported diagnostic radiation history in BRCA1/2 mutation carriers.

Investigational new drugs

Two-stage model-based clinical trial design to optimize phase I development of novel anticancer agents.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Correction strategies to manage deformations in head-and-neck radiotherapy.

Molecular oncology

Benchmarking biology research organizations using a new, dedicated tool.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

3D Dosimetric verification of volumetric-modulated arc therapy by portal dosimetry.

Breast cancer research and treatment

Physical activity and the risk of breast cancer in BRCA1/2 mutation carriers.

European journal of cancer (Oxford, England : 1990)

Personality is associated with health status and impact of cancer among melanoma survivors.

Acta oto-laryngologica

No hearing loss after repeated courses of tobramycin in cystic fibrosis patients.

EMBO reports

Integrin-TGF-beta crosstalk in fibrosis, cancer and wound healing.

Cancer Research

Novel candidate cancer genes identified by a large-scale cross-species comparative oncogenomics approach

26-01-2010

Cancer research

Insertional mutagenesis in mice deficient for p15Ink4b, p16Ink4a, p21Cip1, and p27Kip1 reveals cancer gene interactions and correlations with tumor phenotypes.

15-01-2010

Clinical cancer research : an official journal of the American Association for Cancer Research

Integration of DNA copy number alterations and prognostic gene expression signatures in breast cancer patients.

15-01-2010

Nederlands tijdschrift voor geneeskunde

[Secondary use of human tissue: consent and better information required].

07-01-2010

Oncogene

Frat oncoproteins act at the crossroad of canonical and noncanonical Wnt-signaling pathways.

07-01-2010

Proceedings of the National Academy of Sciences of the United States of America

Recombination-induced tag exchange to track old and new proteins.

05-01-2010

Biomedical chromatography : BMC

High-performance liquid chromatography coupled with mass spectrometry for the quantitative analysis of vinca-alkaloids in biological matrices: a concise survey from the literature.

Annals of oncology : official journal of the European Society for Medical Oncology

The impact of inter-observer variation in pathological assessment of node-negative breast cancer on clinical risk assessment and patient selection for adjuvant systemic treatment.

European journal of cancer (Oxford, England : 1990)

New opportunities for drug outcomes research in cancer patients: the linkage of the Eindhoven Cancer Registry and the PHARMO Record Linkage System.

Genes & development

Tumorigenicity of the miR-17-92 cluster distilled.

Laboratory animals

Validation of intratracheal instillation of lung tumour cells in mice using single photon emission computed tomography/computed tomography imaging.

Breast cancer research and treatment

Concordance of clinical and molecular breast cancer subtyping in the context of preoperative chemotherapy response.

PLoS computational biology

Identification of networks of co-occurring, tumor-related DNA copy number changes using a genome-wide scoring approach.

Clinical cancer research : an official journal of the American Association for Cancer Research

A high-throughput pharmaceutical screen identifies compounds with specific toxicity against BRCA2-deficient tumors.

The Journal of pathology

A tissue reconstitution model to study cancer cell-intrinsic and -extrinsic factors in mammary tumourigenesis.

Nucleosides, nucleotides & nucleic acids

Facile small scale synthesis of nucleoside 5'-phosphate mixtures.

Clinical cancer research : an official journal of the American Association for Cancer Research

P-glycoprotein (P-gp/Abcb1), Abcc2, and Abcc3 determine the pharmacokinetics of etoposide.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

The use of fluorescent dyes and probes in surgical oncology.

BioEssays : news and reviews in molecular, cellular and developmental biology

G protein-coupled receptors: the inside story.

The Journal of clinical investigation

CD27 sustains survival of CTLs in virus-infected nonlymphoid tissue in mice by inducing autocrine IL-2 production.

Clinical pharmacology and therapeutics

Intravenous-to-oral switch in anticancer chemotherapy: a focus on docetaxel and paclitaxel.

Proc Natl Acad Sci U S A: Proceedings of the National Academy of Sciences of the United States of America

Error-prone translesion replication of damaged DNA suppresses skin carcinogenesis by controlling inflammatory hyperplasia

22-12-2009

Breast cancer research : BCR

Combined effects of single nucleotide polymorphisms TP53 R72P and MDM2 SNP309, and p53 expression on survival of breast cancer patients.

22-12-2009

Oncogene

Loss-of-function genetic screens as a tool to improve the diagnosis and treatment of cancer.

17-12-2009

Journal of the National Cancer Institute

Estrogen receptor-alpha phosphorylation at serine-118 and tamoxifen response in breast cancer.

16-12-2009

Journal of the National Cancer Institute

Mortality from lymphohematopoietic malignancies and brain cancer among embalmers exposed to formaldehyde.

16-12-2009

Clinical cancer research : an official journal of the American Association for Cancer Research

ABCC2, ABCC3, and ABCB1, but not CYP3A, Protect against Trabectedin-Mediated Hepatotoxicity.

15-12-2009

The Biochemical journal

Fas/CD95 down-regulation in lymphoma cells through acquired alkyllysophospholipid resistance: partial role of associated sphingomyelin deficiency.

14-12-2009

Journal of pharmaceutical and biomedical analysis

The bioanalysis of the monoclonal antibody trastuzumab by high-performance liquid chromatography with fluorescence detection after immuno-affinity purification from human serum.

05-12-2009

The EMBO journal

Histone H1 binding is inhibited by histone variant H3.3.

02-12-2009

Methods in molecular biology (Clifton, N.J.)

Studying drug resistance using genetically engineered mouse models for breast cancer.

02-12-2009

Cancer research

Absence of both cytochrome P450 3A and P-glycoprotein dramatically increases docetaxel oral bioavailability and risk of intestinal toxicity.

International journal of radiation oncology, biology, physics

Roles of radiation dose and chemotherapy in the etiology of stomach cancer as a second malignancy.

Molecular oncology

Review on early technology assessments of nanotechnologies in oncology.

Cancer treatment reviews

High-grade glioma mouse models and their applicability for preclinical testing.

Biochimica et biophysica acta

Metastasis mechanisms.

Drug metabolism and disposition: the biological fate of chemicals

Inhibition and stimulation of intestinal and hepatic CYP3A activity: studies in humanized CYP3A4 transgenic mice using triazolam.