Publications

Scientific reports

Buparlisib is a brain penetrable pan-PI3K inhibitor.

17-07-2018

Cancer

More frequent use of health care services among distressed compared with nondistressed survivors of lymphoma and chronic lymphocytic leukemia: Results from the population-based PROFILES registry.

15-07-2018

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Bioanalysis of ibrutinib, and its dihydrodiol- and glutathione cycle metabolites by liquid chromatography-tandem mass spectrometry.

15-07-2018

J Clin Oncol.

Risk of Solid Cancer After Treatment of Testicular Germ Cell Cancer in the Platinum Era

10-07-2018

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Loss of Chromosome 18q11.2-q12.1 Is Predictive for Survival in Patients With Metastatic Colorectal Cancer Treated With Bevacizumab.

10-07-2018

Journal of cell science

Chromosomes trapped in micronuclei are liable to segregation errors.

09-07-2018

Nederlands tijdschrift voor geneeskunde

[Freud and colorectal cancer guideline adherence in the Netherlands].

05-07-2018

Epigenetics & chromatin

Correction to: DamID profiling of dynamic Polycomb-binding sites in Drosophila imaginal disc development and tumorigenesis.

03-07-2018

Cell reports

Systemic Loss and Gain of Chromatin Architecture throughout Zebrafish Development.

03-07-2018

ImmunoHorizons

Breadth and Dynamics of HLA-A2- and HLA-B7-Restricted CD8⁺ T Cell Responses against Nonstructural Viral Proteins in Acute Human Tick-Borne Encephalitis Virus Infection.

02-07-2018

Biochimica et biophysica acta. Molecular basis of disease

TRPM7 controls mesenchymal features of breast cancer cells by tensional regulation of SOX4.

01-07-2018

Nature genetics

A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer.

01-07-2018

Anti-cancer drugs

Real-world use, safety, and survival of ipilimumab in metastatic cutaneous melanoma in The Netherlands.

01-07-2018

Oral oncology

Clinicopathological characteristics and outcome of 31 patients with ETV6-NTRK3 fusion gene confirmed (mammary analogue) secretory carcinoma of salivary glands.

01-07-2018

Nature medicine

A transcriptionally and functionally distinct PD-1⁺ CD8⁺ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade.

01-07-2018

Urologic oncology

Mechanistic target of rapamycin (MTOR) protein expression in the tumor and its microenvironment correlates with more aggressive pathology at cystectomy.

01-07-2018

Journal of the National Cancer Institute

Colorectal Adenomas and Cancers After Childhood Cancer Treatment: A DCOG-LATER Record Linkage Study.

01-07-2018

Contact dermatitis

Palladium-induced granulomas analysed with inductively coupled plasma mass spectrometry.

01-07-2018

Cell research

MAP3K1 and MAP2K4 mutations are associated with sensitivity to MEK inhibitors in multiple cancer models.

01-07-2018

Anti-cancer drugs

Real-world healthcare costs of ipilimumab in patients with advanced cutaneous melanoma in The Netherlands.

01-07-2018

Cancer immunology research

Subcellular Localization of Antigen in Keratinocytes Dictates Delivery of CD4⁺ T-cell Help for the CTL Response upon Therapeutic DNA Vaccination into the Skin.

01-07-2018

Cancer prevention research (Philadelphia, Pa.)

Evaluation of Cancer-Associated DNA Copy Number Events in Colorectal (Advanced) Adenomas.

01-07-2018

Neoplasia (New York, N.Y.)

Improved Brain Penetration and Antitumor Efficacy of Temozolomide by Inhibition of ABCB1 and ABCG2.

01-07-2018

Nature medicine

SHP2 is required for growth of KRAS-mutant non-small-cell lung cancer in vivo.

01-07-2018

Physics and imaging in radiation oncology

Biochemical recurrence prediction after radiotherapy for prostate cancer with T2w magnetic resonance imaging radiomic features.

01-07-2018

The European journal of health economics : HEPAC : health economics in prevention and care

Cost-utility and cost-effectiveness of physical exercise during adjuvant chemotherapy.

01-07-2018

PLoS biology

Decoding the chromatin proteome of a single genomic locus by DNA sequencing.

01-07-2018

The Lancet. Oncology

Adjuvant therapy in resectable gastric cancer-the CRITICS trial - Authors' reply.

01-07-2018

Annals of surgery

Response to: "DCIS and Breast Cancer: Challenging the Paradigm".

01-07-2018

Drug and alcohol dependence

Exploring the role of low-frequency and rare exonic variants in alcohol and tobacco use.

01-07-2018

Nature cell biology

Dynamic kinetochore size regulation promotes microtubule capture and chromosome biorientation in mitosis.

01-07-2018

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Tumor-infiltrating lymphocytes and ductal carcinoma in situ of the breast: friends or foes?

01-07-2018

Arteriosclerosis, thrombosis, and vascular biology

Weibel-Palade Body Localized Syntaxin-3 Modulates Von Willebrand Factor Secretion From Endothelial Cells.

01-07-2018

Oncotarget

Toll-like receptor 4: a target for chemoprevention of hepatocellular carcinoma in obesity and steatohepatitis.

29-06-2018

Oncotarget

MACROD2 expression predicts response to 5-FU-based chemotherapy in stage III colon cancer.

29-06-2018

Cell reports

Neutrophils Kill Antibody-Opsonized Cancer Cells by Trogoptosis.

26-06-2018

Frontiers in cellular and infection microbiology

Macrophage Activation Marker Neopterin: A Candidate Biomarker for Treatment Response and Relapse in Visceral Leishmaniasis.

19-06-2018

Nederlands tijdschrift voor geneeskunde

[Ethical dilemmas in a general practitioner's clinic due to incidental findings resulting from whole genome sequencing].

15-06-2018

Nederlands tijdschrift voor geneeskunde

[Recent treatment results for metastatic melanoma: data from the Dutch Melanoma Treatment Registry].

15-06-2018

Nederlands tijdschrift voor geneeskunde

[Unsolicited genomic findings in daily clinical practice].

15-06-2018

Cancer cell

Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality.

11-06-2018

International journal of pharmaceutics

Solubility and bioavailability improvement of pazopanib hydrochloride.

10-06-2018

Molecular cell

Kinetics and Fidelity of the Repair of Cas9-Induced Double-Strand DNA Breaks.

07-06-2018

Nederlands tijdschrift voor geneeskunde

[The accuracy of patients' perceptions of the risks associated with localised prostate cancer treatments].

07-06-2018

Journal of osteoporosis

Glycemic Control and Bone Turnover in Older Mexican Americans with Type 2 Diabetes.

05-06-2018

Epigenetics & chromatin

DamID profiling of dynamic Polycomb-binding sites in Drosophila imaginal disc development and tumorigenesis.

05-06-2018

Health and quality of life outcomes

Understanding the quality of life (QOL) issues in survivors of cancer: towards the development of an EORTC QOL cancer survivorship questionnaire.

04-06-2018

Chembiochem : a European journal of chemical biology

Bioorthogonally Applicable Fluorescence Deactivation Strategy for Receptor Kinetics Study and Theranostic Pretargeting Approaches.

04-06-2018

European journal of clinical pharmacology

The impact of liver resection on the dihydrouracil:uracil plasma ratio in patients with colorectal liver metastases.

01-06-2018

Neuroradiology

Multi-center reproducibility of structural, diffusion tensor, and resting state functional magnetic resonance imaging measures.

01-06-2018

Buparlisib is a brain penetrable pan-PI3K inhibitor.

More frequent use of health care services among distressed compared with nondistressed survivors of lymphoma and chronic lymphocytic leukemia: Results from the population-based PROFILES registry.

Bioanalysis of ibrutinib, and its dihydrodiol- and glutathione cycle metabolites by liquid chromatography-tandem mass spectrometry.

Risk of Solid Cancer After Treatment of Testicular Germ Cell Cancer in the Platinum Era

Loss of Chromosome 18q11.2-q12.1 Is Predictive for Survival in Patients With Metastatic Colorectal Cancer Treated With Bevacizumab.

Chromosomes trapped in micronuclei are liable to segregation errors.

[Freud and colorectal cancer guideline adherence in the Netherlands].

Correction to: DamID profiling of dynamic Polycomb-binding sites in Drosophila imaginal disc development and tumorigenesis.

Systemic Loss and Gain of Chromatin Architecture throughout Zebrafish Development.

Breadth and Dynamics of HLA-A2- and HLA-B7-Restricted CD8+ T Cell Responses against Nonstructural Viral Proteins in Acute Human Tick-Borne Encephalitis Virus Infection.

TRPM7 controls mesenchymal features of breast cancer cells by tensional regulation of SOX4.

A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer.

Real-world use, safety, and survival of ipilimumab in metastatic cutaneous melanoma in The Netherlands.

Clinicopathological characteristics and outcome of 31 patients with ETV6-NTRK3 fusion gene confirmed (mammary analogue) secretory carcinoma of salivary glands.

A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade.

Mechanistic target of rapamycin (MTOR) protein expression in the tumor and its microenvironment correlates with more aggressive pathology at cystectomy.

Colorectal Adenomas and Cancers After Childhood Cancer Treatment: A DCOG-LATER Record Linkage Study.

Palladium-induced granulomas analysed with inductively coupled plasma mass spectrometry.

MAP3K1 and MAP2K4 mutations are associated with sensitivity to MEK inhibitors in multiple cancer models.

Real-world healthcare costs of ipilimumab in patients with advanced cutaneous melanoma in The Netherlands.

Subcellular Localization of Antigen in Keratinocytes Dictates Delivery of CD4+ T-cell Help for the CTL Response upon Therapeutic DNA Vaccination into the Skin.

Evaluation of Cancer-Associated DNA Copy Number Events in Colorectal (Advanced) Adenomas.

Improved Brain Penetration and Antitumor Efficacy of Temozolomide by Inhibition of ABCB1 and ABCG2.

SHP2 is required for growth of KRAS-mutant non-small-cell lung cancer in vivo.

Biochemical recurrence prediction after radiotherapy for prostate cancer with T2w magnetic resonance imaging radiomic features.

Cost-utility and cost-effectiveness of physical exercise during adjuvant chemotherapy.

Decoding the chromatin proteome of a single genomic locus by DNA sequencing.

Adjuvant therapy in resectable gastric cancer-the CRITICS trial - Authors' reply.

Response to: "DCIS and Breast Cancer: Challenging the Paradigm".

Exploring the role of low-frequency and rare exonic variants in alcohol and tobacco use.

Dynamic kinetochore size regulation promotes microtubule capture and chromosome biorientation in mitosis.

Tumor-infiltrating lymphocytes and ductal carcinoma in situ of the breast: friends or foes?

Weibel-Palade Body Localized Syntaxin-3 Modulates Von Willebrand Factor Secretion From Endothelial Cells.

Toll-like receptor 4: a target for chemoprevention of hepatocellular carcinoma in obesity and steatohepatitis.

MACROD2 expression predicts response to 5-FU-based chemotherapy in stage III colon cancer.

Neutrophils Kill Antibody-Opsonized Cancer Cells by Trogoptosis.

Macrophage Activation Marker Neopterin: A Candidate Biomarker for Treatment Response and Relapse in Visceral Leishmaniasis.

[Ethical dilemmas in a general practitioner's clinic due to incidental findings resulting from whole genome sequencing].

[Recent treatment results for metastatic melanoma: data from the Dutch Melanoma Treatment Registry].

[Unsolicited genomic findings in daily clinical practice].

Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality.

Solubility and bioavailability improvement of pazopanib hydrochloride.

Kinetics and Fidelity of the Repair of Cas9-Induced Double-Strand DNA Breaks.

[The accuracy of patients' perceptions of the risks associated with localised prostate cancer treatments].

Glycemic Control and Bone Turnover in Older Mexican Americans with Type 2 Diabetes.

DamID profiling of dynamic Polycomb-binding sites in Drosophila imaginal disc development and tumorigenesis.

Understanding the quality of life (QOL) issues in survivors of cancer: towards the development of an EORTC QOL cancer survivorship questionnaire.

Bioorthogonally Applicable Fluorescence Deactivation Strategy for Receptor Kinetics Study and Theranostic Pretargeting Approaches.

The impact of liver resection on the dihydrouracil:uracil plasma ratio in patients with colorectal liver metastases.

Multi-center reproducibility of structural, diffusion tensor, and resting state functional magnetic resonance imaging measures.

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Breadth and Dynamics of HLA-A2- and HLA-B7-Restricted CD8⁺ T Cell Responses against Nonstructural Viral Proteins in Acute Human Tick-Borne Encephalitis Virus Infection.

A transcriptionally and functionally distinct PD-1⁺ CD8⁺ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade.

Subcellular Localization of Antigen in Keratinocytes Dictates Delivery of CD4⁺ T-cell Help for the CTL Response upon Therapeutic DNA Vaccination into the Skin.