Publications

Angiogenesis

Platelet function is disturbed by the angiogenesis inhibitors sunitinib and sorafenib, but unaffected by bevacizumab.

Clinical pharmacokinetics

Pharmacokinetic Optimization of Everolimus Dosing in Oncology: A Randomized Crossover Trial.

The British journal of surgery

Association between hospital volume and quality of gastric cancer surgery in the CRITICS trial.

Cancer chemotherapy and pharmacology

Phase I study of combined indomethacin and platinum-based chemotherapy to reduce platinum-induced fatty acids.

Human mutation

The BRCA2 c.68-7T > A variant is not pathogenic: A model for clinical calibration of spliceogenicity.

Immunology

The opposing roles of CD4⁺ T cells in anti-tumour immunity.

27-04-2018

Journal of extracellular vesicles

Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8.

27-04-2018

Scientific reports

E-cadherin breast tumor expression, risk factors and survival: Pooled analysis of 5,933 cases from 12 studies in the Breast Cancer Association Consortium.

26-04-2018

Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry

Trabecular Bone Score Is a Valuable Addition to Bone Mineral Density for Bone Quality Assessment in Older Mexican American Women With Type 2 Diabetes.

25-04-2018

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

American Society of Clinical Oncology Statement: Biosimilars in Oncology.

20-04-2018

Trials

ENdometrial cancer SURvivors' follow-up carE (ENSURE): Less is more? Evaluating patient satisfaction and cost-effectiveness of a reduced follow-up schedule: study protocol of a randomized controlled trial.

16-04-2018

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Bioanalytical assay for the quantification of the ALK inhibitor lorlatinib in mouse plasma using liquid chromatography-tandem mass spectrometry.

15-04-2018

PloS one

What drives centralisation in cancer care?

13-04-2018

Oncotarget

Precision cancer therapy: profiting from tumor specific defects in the DNA damage tolerance system.

10-04-2018

Cancer cell

T Cell Dysfunction in Cancer.

09-04-2018

Oncotarget

Fanconi anemia and homologous recombination gene variants are associated with functional DNA repair defects in vitro and poor outcome in patients with advanced head and neck squamous cell carcinoma.

06-04-2018

Molecular cell

ZUFSP Deubiquitylates K63-Linked Polyubiquitin Chains to Promote Genome Stability.

05-04-2018

The EMBO journal

Paligenosis: prepare to regenerate!

BMJ open diabetes research & care

Mexican American and South Asian population-based cohorts reveal high prevalence of type 2 diabetes and crucial differences in metabolic phenotypes.

JMIR cancer

Analysis of Content Shared in Online Cancer Communities: Systematic Review.

Cell reports

Multifaceted Impact of MicroRNA 493-5p on Genome-Stabilizing Pathways Induces Platinum and PARP Inhibitor Resistance in BRCA2-Mutated Carcinomas.

Lasers in medical science

Nerve detection during surgery: optical spectroscopy for peripheral nerve localization.

Psycho-oncology

Effects and moderators of psychosocial interventions on quality of life, and emotional and social function in patients with cancer: An individual patient data meta-analysis of 22 RCTs.

Psycho-oncology

Managing unsolicited findings in genomics: A qualitative interview study with cancer patients.

Breast cancer research and treatment

Enrichment of high-grade tumors in breast cancer gene expression studies.

Brain imaging and behavior

Changes in brain white matter integrity after systemic treatment for breast cancer: a prospective longitudinal study.

Clinical pharmacokinetics

PARP Inhibitors in the Treatment of Triple-Negative Breast Cancer.

International journal of epidemiology

Joint associations of a polygenic risk score and environmental risk factors for breast cancer in the Breast Cancer Association Consortium.

Biomedical chromatography : BMC

Development and validation of a liquid chromatography-tandem mass spectrometry analytical method for the therapeutic drug monitoring of eight novel anticancer drugs.

European journal of cancer (Oxford, England : 1990)

European Academy of Cancer Sciences-Designation of Comprehensive Cancer Centres of Excellence.

Familial cancer

Cancer patients' intentions towards receiving unsolicited genetic information obtained using next-generation sequencing.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Quality of life of patients with locally advanced head and neck cancer treated with induction chemotherapy followed by cisplatin-containing chemoradiotherapy in the Dutch CONDOR study: a randomized controlled trial.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Cost-effectiveness of High-performance Biomarker Tests vs Fecal Immunochemical Test for Noninvasive Colorectal Cancer Screening.

International journal of computer assisted radiology and surgery

Real-time wireless tumor tracking during breast conserving surgery.

Molecular cancer therapeutics

PIM Kinases Are a Potential Prognostic Biomarker and Therapeutic Target in Neuroblastoma.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Standard whole prostate gland radiotherapy with and without lesion boost in prostate cancer: Toxicity in the FLAME randomized controlled trial.

Clinical & experimental metastasis

Potential impact of invasive surgical procedures on primary tumor growth and metastasis.

Psychological medicine

Leukocyte telomere length and personality: associations with the Big Five and Type D personality traits.

British journal of clinical pharmacology

Fixed dosing of intravenous tocilizumab in rheumatoid arthritis. Results from a population pharmacokinetic analysis.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

The impact of prostate cancer diagnosis and treatment decision-making on health-related quality of life before treatment onset.

Cancer discovery

E-Cadherin/ROS1 Inhibitor Synthetic Lethality in Breast Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research

Chemical Profiling of Primary Mesothelioma Cultures Defines Subtypes with Different Expression Profiles and Clinical Responses.

Journal of clinical and experimental neuropsychology

Reliability and validity of a self-administered tool for online neuropsychological testing: The Amsterdam Cognition Scan.

Journal of biomedical optics

Feasibility of using optical coherence tomography to detect acute radiation-induced esophageal damage in small animal models.

JNCI cancer spectrum

Oral Contraceptive Use and Breast Cancer Risk: Retrospective and Prospective Analyses From a BRCA1 and BRCA2 Mutation Carrier Cohort Study.

Melanoma research

Clinical and radiological response of BRAF inhibition and MEK inhibition in patients with brain metastases from BRAF-mutated melanoma.

The Journal of urology

Navigation of Fluorescence Cameras during Soft Tissue Surgery-Is it Possible to Use a Single Navigation Setup for Various Open and Laparoscopic Urological Surgery Applications?

British journal of sports medicine

Which exercise prescriptions improve quality of life and physical function in patients with cancer during and following treatment? A systematic review and meta-analysis of randomised controlled trials.

European radiology

Magnetic resonance imaging for clinical management of rectal cancer: Updated recommendations from the 2016 European Society of Gastrointestinal and Abdominal Radiology (ESGAR) consensus meeting.