Publications

Cancer research

BRCA2-deficient sarcomatoid mammary tumors exhibit multidrug resistance.

15-02-2015

Practical radiation oncology

Probabilistic evaluation of target dose deterioration in dose painting by numbers for stage II/III lung cancer.

15-02-2015

The Cochrane database of systematic reviews

Conservative interventions for preventing clinically detectable upper-limb lymphoedema in patients who are at risk of developing lymphoedema after breast cancer therapy.

13-02-2015

The EMBO journal

BRCA1 and CtIP promote alternative non-homologous end-joining at uncapped telomeres.

03-02-2015

Proceedings of the National Academy of Sciences of the United States of America

The first step of peptide selection in antigen presentation by MHC class I molecules.

03-02-2015

Advances in cancer research

Apical ABC transporters and cancer chemotherapeutic drug disposition.

03-02-2015

Annals of surgery

Marking axillary lymph nodes with radioactive iodine seeds for axillary staging after neoadjuvant systemic treatment in breast cancer patients: the MARI procedure.

01-02-2015

DNA repair

DNA helicases FANCM and DDX11 are determinants of PARP inhibitor sensitivity.

01-02-2015

Melanoma research

Cross-cultural development of a quality-of-life measure for patients with melanoma: phase 3 testing of an EORTC Melanoma Module.

01-02-2015

Annals of surgical oncology

Does adjuvant chemoradiotherapy improve the prognosis of gastric cancer after an r1 resection? Results from a dutch cohort study.

01-02-2015

European urology

The molecular background of urothelial cancer: ready for action?

01-02-2015

Investigational new drugs

Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy.

01-02-2015

Carcinogenesis

Inherited variants in the inner centromere protein (INCENP) gene of the chromosomal passenger complex contribute to the susceptibility of ER-negative breast cancer.

01-02-2015

Clinical genitourinary cancer

Neoadjuvant taxane-based combination chemotherapy in patients with advanced penile cancer.

01-02-2015

Nature genetics

Identification of six new susceptibility loci for invasive epithelial ovarian cancer.

01-02-2015

World journal of surgery

Implementation of a standardized HIPEC protocol improves outcome for peritoneal malignancy.

01-02-2015

Head & neck

Sensorineural hearing loss in patients with head and neck cancer after chemoradiotherapy and radiotherapy: a systematic review of the literature.

01-02-2015

International journal of pharmaceutics

Stability of oxaliplatin in chloride-containing carrier solutions used in hyperthermic intraperitoneal chemotherapy.

01-02-2015

Investigational new drugs

Pharmacokinetics and excretion of (14)C-lenvatinib in patients with advanced solid tumors or lymphomas.

01-02-2015

Oncogene

Delaying mitotic exit downregulates FLIP expression and strongly sensitizes tumor cells to TRAIL.

29-01-2015

Ecancermedicalscience

Report from the OECI Oncology Days 2014.

28-01-2015

Journal of translational medicine

NHS-IL2 combined with radiotherapy: preclinical rationale and phase Ib trial results in metastatic non-small cell lung cancer following first-line chemotherapy.

27-01-2015

J Pathol.: The journal of pathology

Spontaneous bone metastases in a preclinical orthotopic model of invasive lobular carcinoma; the effect of pharmacological targeting TGFβ receptor I kinase

23-01-2015

Science (New York, N.Y.)

T cell immunity. Functional heterogeneity of human memory CD4⁺ T cell clones primed by pathogens or vaccines.

23-01-2015

JMIR research protocols

Development of MijnAVL, an Interactive Portal to Empower Breast and Lung Cancer Survivors: An Iterative, Multi-Stakeholder Approach.

22-01-2015

Oncogene

A chromatin modifier genetic screen identifies SIRT2 as a modulator of response to targeted therapies through the regulation of MEK kinase activity.

22-01-2015

Molecular cell

Transcription initiation determines its end.

22-01-2015

Molecular cell

Yeast PP4 interacts with ATR homolog Ddc2-Mec1 and regulates checkpoint signaling.

22-01-2015

J Proteome Res.: Journal of proteome research

The use of mass spectrometry imaging to predict treatment response of patient-derived xenograft models of triple-negative breast cancer

20-01-2015

Cell reports

Prolonged Ezh2 Depletion in Glioblastoma Causes a Robust Switch in Cell Fate Resulting in Tumor Progression.

20-01-2015

Oncoscience

P-gp and taxanes.

17-01-2015

Experimental cell research

Quantitative imaging of focal adhesion dynamics and their regulation by HGF and Rap1 signaling.

15-01-2015

Cancer cell

Biomarkers in cancer immunotherapy.

12-01-2015

American journal of human genetics

Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1.

08-01-2015

British journal of cancer

Increased stomach cancer risk following radiotherapy for testicular cancer.

06-01-2015

International journal of cancer

Human OATP1B1, OATP1B3 and OATP1A2 can mediate the in vivo uptake and clearance of docetaxel.

01-01-2015

Antimicrobial agents and chemotherapy

Systematic review of biomarkers to monitor therapeutic response in leishmaniasis.

01-01-2015

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

Lymphovascular space invasion and the treatment of stage I endometrioid endometrial cancer.

01-01-2015

Journal of cell science

N-terminal acetylation and replicative age affect proteasome localization and cell fitness during aging.

01-01-2015

Nature genetics

A conditional piggyBac transposition system for genetic screening in mice identifies oncogenic networks in pancreatic cancer.

01-01-2015

Nucleic acids research

Roles of PCNA ubiquitination and TLS polymerases κ and η in the bypass of methyl methanesulfonate-induced DNA damage.

01-01-2015

European journal of cancer (Oxford, England : 1990)

Management of sporadic desmoid-type fibromatosis: a European consensus approach based on patients' and professionals' expertise - a sarcoma patients EuroNet and European Organisation for Research and Treatment of Cancer/Soft Tissue and Bone Sarcoma Group initiative.

01-01-2015

Psychopharmacology

Cognitive impact of cytotoxic agents in mice.

01-01-2015

Nature medicine

High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma.

01-01-2015

The journal of pathology. Clinical research

Performance of automated scoring of ER, PR, HER2, CK5/6 and EGFR in breast cancer tissue microarrays in the Breast Cancer Association Consortium.

01-01-2015

Pharmaceutical research

Breast cancer resistance protein (BCRP/ABCG2) and P-glycoprotein (P-GP/ABCB1) restrict oral availability and brain accumulation of the PARP inhibitor rucaparib (AG-014699).

01-01-2015

Menopause (New York, N.Y.)

Cognitive functioning during long-term tamoxifen treatment in postmenopausal women with breast cancer.

01-01-2015

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Candidate genetic modifiers for breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers.

01-01-2015

International immunology

Therapeutic use of anti-CTLA-4 antibodies.

01-01-2015

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

The value of optical coherence tomography in determining surgical margins in squamous cell carcinoma of the vulva: a single-center prospective study.

01-01-2015