Publications

Journal of pharmaceutical and biomedical analysis

Ultra-sensitive LC-MS/MS method for the quantification of gemcitabine and its metabolite 2',2'-difluorodeoxyuridine in human plasma for a microdose clinical trial.

Immunity

Regulation and Function of the PD-L1 Checkpoint.

British journal of cancer

High burden of subsequent malignant neoplasms and cardiovascular disease in long-term Hodgkin lymphoma survivors.

Nature communications

Wnt ligands influence tumour initiation by controlling the number of intestinal stem cells.

19-03-2018

Nature communications

SUMO targets the APC/C to regulate transition from metaphase to anaphase.

16-03-2018

The Journal of cell biology

Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling.

05-03-2018

Molecular systems biology

Targeting CDK2 overcomes melanoma resistance against BRAF and Hsp90 inhibitors.

05-03-2018

Oncotarget

A single digital droplet PCR assay to detect multiple KIT exon 11 mutations in tumor and plasma from patients with gastrointestinal stromal tumors.

02-03-2018

JAMA oncology.

Breast implants and the risk of anaplastic large cell lymphoma in the breast.

BJU international

The accuracy of patients' perceptions of the risks associated with localised prostate cancer treatments.

Cancer metastasis reviews

Long non-coding RNAs in metastasis.

Diseases of the colon and rectum

A Pattern-Based Approach Combining Tumor Morphology on MRI With Distinct Signal Patterns on Diffusion-Weighted Imaging to Assess Response of Rectal Tumors After Chemoradiotherapy.

Toxicology in vitro : an international journal published in association with BIBRA

Drug toxicity profiling of a Saccharomyces cerevisiae deubiquitinase deletion panel shows that acetaminophen mimics tyrosine.

Head & neck

Androgen deprivation therapy for androgen receptor-positive advanced salivary duct carcinoma: A nationwide case series of 35 patients in The Netherlands.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Monitoring early changes in rectal tumor morphology and volume during 5 weeks of preoperative chemoradiotherapy - An evaluation with sequential MRIs.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Improved pharmacodynamic (PD) assessment of low dose PARP inhibitor PD activity for radiotherapy and chemotherapy combination trials.

Radiologic clinics of North America

Role of Prostate MR Imaging in Radiation Oncology.

Lasers in surgery and medicine

Nerve detection using optical spectroscopy, an evaluation in four different models: In human and swine, in-vivo, and post mortem.

Oncogene

Insertional mutagenesis in a HER2-positive breast cancer model reveals ERAS as a driver of cancer and therapy resistance.

Clinical rehabilitation

Feasibility of a home-based exercise intervention with remote guidance for patients with stable grade II and III gliomas: a pilot randomized controlled trial.

Genetic testing and molecular biomarkers

Patients' Attitudes Towards the Return of Incidental Findings After Research with Residual Tissue: A Mixed Methods Study.

Protein science : a publication of the Protein Society

Homology-based hydrogen bond information improves crystallographic structures in the PDB.

JAMA oncology

Breast Implants and the Risk of Anaplastic Large-Cell Lymphoma in the Breast.

Journal of neuro-oncology

EpCAM-based assays for epithelial tumor cell detection in cerebrospinal fluid.

Magnetic resonance in medicine

Performance of a fast and high-resolution multi-echo spin-echo sequence for prostate T₂ mapping across multiple systems.

Current opinion in urology

Computer-assisted surgery: virtual- and augmented-reality displays for navigation during urological interventions.

European urology

Atezolizumab in Platinum-treated Locally Advanced or Metastatic Urothelial Carcinoma: Outcomes by Prior Number of Regimens.

Oral oncology

Baseline peripheral blood leukocytosis: Biological marker predicts outcome in oropharyngeal cancer, regardless of HPV-status.

Bioinformatics (Oxford, England)

Bayesian data integration for quantifying the contribution of diverse measurements to parameter estimates.

Gut

Double somatic mutations in mismatch repair genes are frequent in colorectal cancer after Hodgkin's lymphoma treatment.

Pharmacological research

P-glycoprotein (MDR1/ABCB1) and Breast Cancer Resistance Protein (BCRP/ABCG2) affect brain accumulation and intestinal disposition of encorafenib in mice.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

Recurrent Cancer Is Associated With Dissatisfaction With Care-A Longitudinal Analysis Among Ovarian and Endometrial Cancer Patients.

Nature communications

FcαRI co-stimulation converts human intestinal CD103⁺ dendritic cells into pro-inflammatory cells through glycolytic reprogramming.

28-02-2018

BMC cancer

The association of diabetes mellitus and insulin treatment with expression of insulin-related proteins in breast tumors.

27-02-2018

Lancet (London, England)

Atezolizumab versus chemotherapy in patients with platinum-treated locally advanced or metastatic urothelial carcinoma (IMvigor211): a multicentre, open-label, phase 3 randomised controlled trial.

24-02-2018

Nature

TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells.

22-02-2018

PLOS one

Improving stability of prediction models based on correlated omics data by using network approaches

20-02-2018

Cancer cell

Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma.

12-02-2018

BMC health services research

Implementing large scale fast track diagnostics in a comprehensive cancer center, pre- and post-measurement data.

07-02-2018

Acta dermato-venereologica

Development and Validation of the Basal and Squamous Cell Carcinoma Quality of Life (BaSQoL) Questionnaire.

07-02-2018

Cell reports

BUB1 Is Essential for the Viability of Human Cells in which the Spindle Assembly Checkpoint Is Compromised.

06-02-2018

BMJ open

Cohort profile: LIFEWORK, a prospective cohort study on occupational and environmental risk factors and health in the Netherlands.

03-02-2018

Science (New York, N.Y.)

Enhancing responses to cancer immunotherapy.

ESMO open

Immune checkpoint inhibition-related colitis: symptoms, endoscopic features, histology and response to management.

Scientific reports

Author Correction: Deep Learning for Fully-Automated Localization and Segmentation of Rectal Cancer on Multiparametric MR.

Wellcome open research

Using mitoribosomal profiling to investigate human mitochondrial translation.

Nature communications

Characterizing steroid hormone receptor chromatin binding landscapes in male and female breast cancer.