Publications

Journal of chromatography. A

Middle-up quantification of therapeutic monoclonal antibodies in human plasma with two dimensional liquid chromatography high resolution mass spectrometry: Adalimumab as a proof of principle.

22-02-2022

Journal of pharmaceutical sciences

Population Pharmacokinetic Modelling to Support the Evaluation of Preclinical Pharmacokinetic Experiments with Lorlatinib.

01-02-2022

Clinical pharmacokinetics

Pharmacokinetic/Pharmacodynamic Modelling of Allopurinol, its Active Metabolite Oxypurinol, and Biomarkers Hypoxanthine, Xanthine and Uric Acid in Hypoxic-Ischemic Encephalopathy Neonates.

01-02-2022

British journal of clinical pharmacology

Hyperhydration with cisplatin does not influence pemetrexed exposure.

01-02-2022

Clinical pharmacology and therapeutics

Effects of the Moderate CYP3A4 Inhibitor Erythromycin on the Pharmacokinetics of Palbociclib: A Randomized Crossover Trial in Patients With Breast Cancer.

01-02-2022

Cancers

Pharmacogenomics of Vincristine-Induced Peripheral Neuropathy in Children with Cancer: A Systematic Review and Meta-Analysis.

26-01-2022

BMC cancer

The influence of docetaxel schedule on treatment tolerability and efficacy in patients with metastatic breast cancer: a systematic review and meta-analysis of randomized controlled trials.

25-01-2022

BMJ open

Plasma concentration guided dosing of drugs used for the treatment of childhood leukaemias: protocol for a systematic review.

03-01-2022

Best practice & research. Clinical obstetrics & gynaecology

Translational and pharmacological principles of hyperthermic intraperitoneal chemotherapy for ovarian cancer.

01-01-2022

European journal of cancer (Oxford, England : 1990)

The association of cisplatin pharmacokinetics and skeletal muscle mass in patients with head and neck cancer: The prospective PLATISMA study.

01-01-2022

Drugs

Optimized Dosing: The Next Step in Precision Medicine in Non-Small-Cell Lung Cancer.

01-01-2022

Targeted oncology

Representativeness of Phase III Trial for Osimertinib in Pretreated Advanced EGFR-Mutated Non-small-cell Lung Cancer Patients and Treatment Outcomes in Clinical Practice.

01-01-2022

Clinical cancer research : an official journal of the American Association for Cancer Research

Precision Dosing of Targeted Therapies Is Ready for Prime Time.

15-12-2021

Cancers

Developing a Nationwide Infrastructure for Therapeutic Drug Monitoring of Targeted Oral Anticancer Drugs: The ON-TARGET Study Protocol.

14-12-2021

JAC-antimicrobial resistance

Aminoglycoside- and glycopeptide-induced ototoxicity in children: a systematic review.

01-12-2021

Breast care (Basel, Switzerland)

Carboplatin-Cyclophosphamide or Paclitaxel without or with Bevacizumab as First-Line Treatment for Metastatic Triple-Negative Breast Cancer (BOOG 2013-01).

01-12-2021

Cancers

Intra-Tumoral Pharmacokinetics of Pazopanib in Combination with Radiotherapy in Patients with Non-Metastatic Soft-Tissue Sarcoma.

18-11-2021

Clinical pharmacokinetics

Correction to: Influence of Malnutrition on the Pharmacokinetics of Drugs Used in the Treatment of Poverty-Related Diseases: A Systematic Review.

01-11-2021

Clinical pharmacology and therapeutics

Response to "Optimized Alectinib Dose Regimen for Treatment of Patients With ALK-Positive NSCLC Based on Robust Pharmacometric Analyses and Clinical Evidence".

01-11-2021

Clinical pharmacokinetics

Pharmacokinetics and Associated Efficacy of Emicizumab in Humans: A Systematic Review.

01-11-2021

Clinical pharmacokinetics

Geographical Variability in Paromomycin Pharmacokinetics Does Not Explain Efficacy Differences between Eastern African and Indian Visceral Leishmaniasis Patients.

01-11-2021

Journal of pharmaceutical and biomedical analysis

Quantification of anti-SARS-CoV-2 antibodies in human serum with LC-QTOF-MS.

25-10-2021

NPJ breast cancer

IHC-based Ki67 as response biomarker to tamoxifen in breast cancer window trials enrolling premenopausal women.

20-10-2021

International journal of cancer

Toxicity of pemetrexed during renal impairment explained-Implications for safe treatment.

15-10-2021

Journal of chromatography. A

A generic sample preparation method for the multiplex analysis of seven therapeutic monoclonal antibodies in human plasma or serum with liquid chromatography-tandem mass spectrometry.

11-10-2021

Therapeutic drug monitoring

Quality Control of Busulfan Plasma Quantitation, Modeling, and Dosing: An Interlaboratory Proficiency Testing Program.

01-10-2021

Frontiers in pharmacology

A Review of CYP3A Drug-Drug Interaction Studies: Practical Guidelines for Patients Using Targeted Oral Anticancer Drugs.

17-09-2021

Clinical pharmacokinetics

Influence of Malnutrition on the Pharmacokinetics of Drugs Used in the Treatment of Poverty-Related Diseases: A Systematic Review.

01-09-2021

EJNMMI research

A physiologically based pharmacokinetic (PBPK) model to describe organ distribution of ⁶⁸Ga-DOTATATE in patients without neuroendocrine tumors.

16-08-2021

British journal of clinical pharmacology

Population pharmacokinetics of clofarabine for allogeneic hematopoietic cell transplantation in paediatric patients.

01-08-2021

Cancer medicine

Worse capecitabine treatment outcome in patients with a low skeletal muscle mass is not explained by altered pharmacokinetics.

01-07-2021

International journal of cancer

A Phase I dose-escalation study of two cycles carboplatin-olaparib followed by olaparib monotherapy in patients with advanced cancer.

15-06-2021

Clinical pharmacology in drug development

A Phase 1 Dose-Escalation Study of Low-Dose Metronomic Treatment With Novel Oral Paclitaxel Formulations in Combination With Ritonavir in Patients With Advanced Solid Tumors.

01-06-2021

The pharmacogenomics journal

Investigating the influence of relevant pharmacogenetic variants on the pharmacokinetics and pharmacodynamics of orally administered docetaxel combined with ritonavir.

01-06-2021

Clinical pharmacokinetics

Population Pharmacokinetics of Docetaxel, Paclitaxel, Doxorubicin and Epirubicin in Pregnant Women with Cancer: A Study from the International Network of Cancer, Infertility and Pregnancy (INCIP).

01-06-2021

ESMO open

Prospective experimental treatment of colorectal cancer patients based on organoid drug responses.

01-06-2021

Molecular cancer therapeutics

Antitumor Activity of NLG207 (Formerly CRLX101) in Combination with Enzalutamide in Preclinical Prostate Cancer Models.

01-05-2021

Clinical pharmacokinetics

Rethinking the Application of Pemetrexed for Patients with Renal Impairment: A Pharmacokinetic Analysis.

01-05-2021

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery

Fibrinogen Degradation Speed as a Predictor of Major Bleeding Complications During Catheter Directed Thrombolysis in Patients with Acute Lower Limb Ischaemia.

01-05-2021

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Development and validation of a combined liquid chromatography tandem-mass spectrometry assay for the quantification of aprepitant and dexamethasone in human plasma to support pharmacokinetic studies in pediatric patients.

01-05-2021

Cancers

Immune Monitoring during Therapy Reveals Activitory and Regulatory Immune Responses in High-Risk Neuroblastoma.

26-04-2021

Nature reviews. Urology

Resistance to second-generation androgen receptor antagonists in prostate cancer.

01-04-2021

European journal of clinical pharmacology

Correction to: Therapeutic drug monitoring of oral targeted antineoplastic drugs.

01-04-2021

The oncologist

Phase I Study of Afatinib and Selumetinib in Patients with KRAS-Mutated Colorectal, Non-Small Cell Lung, and Pancreatic Cancer.

01-04-2021

European journal of clinical pharmacology

Therapeutic drug monitoring of oral targeted antineoplastic drugs.

01-04-2021

Basic & clinical pharmacology & toxicology

Toxicological analysis of azide and cyanide for azide intoxications using gas chromatography.

01-03-2021

Drugs in R&D

Effect of Food on the Pharmacokinetics of the Oral Docetaxel Tablet Formulation ModraDoc006 Combined with Ritonavir (ModraDoc006/r) in Patients with Advanced Solid Tumours.

01-03-2021

Blood

CD4+ T-cell reconstitution predicts survival outcomes after acute graft-versus-host-disease: a dual-center validation.

11-02-2021

Clinical pharmacology and therapeutics

Exposure-Response Analyses of Anaplastic Lymphoma Kinase Inhibitors Crizotinib and Alectinib in Non-Small Cell Lung Cancer Patients.

01-02-2021

European journal of clinical pharmacology

A real or apparent decrease in glomerular filtration rate in patients using olaparib?

01-02-2021