Publications

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

High accumulation of nivolumab in human breast milk: A case report.

British journal of clinical pharmacology

Optimizing carboplatin dosing by an improved prediction of carboplatin clearance using a CT-enhanced estimate of renal function.

Obesity surgery

Impact of Bariatric Surgery in the Short and Long Term: A Need for Time-Dependent Dosing of Drugs.

Clinical pharmacokinetics

Therapeutic Drug Monitoring of Kinase Inhibitors in Oncology.

EJNMMI physics

Predicting [¹⁷⁷Lu]Lu-HA-DOTATATE kidney and tumor accumulation based on [⁶⁸Ga]Ga-HA-DOTATATE diagnostic imaging using semi-physiological population pharmacokinetic modeling.

24-08-2023

Clinical pharmacokinetics

Semi-physiological Enriched Population Pharmacokinetic Modelling to Predict the Effects of Pregnancy on the Pharmacokinetics of Cytotoxic Drugs.

01-08-2023

CPT: pharmacometrics & systems pharmacology

Population pharmacokinetic dosimetry model using imaging data to assess variability in pharmacokinetics of ¹⁷⁷ Lu-PSMA-617 in prostate cancer patients.

01-08-2023

Clinical pharmacokinetics

CYP3A4*22 Genotype-Guided Dosing of Kinase Inhibitors in Cancer Patients.

01-08-2023

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Design and statistics of pharmacokinetic drug-drug, herb-drug, and food-drug interaction studies in oncology patients.

Gynecologic oncology

WEE1 inhibitor adavosertib in combination with carboplatin in advanced TP53 mutated ovarian cancer: A biomarker-enriched phase II study.

Clinical pharmacokinetics

Predicting Chemotherapy Distribution into Breast Milk for Breastfeeding Women Using a Population Pharmacokinetic Approach.

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

Genetic variants found in paediatric oncology patients with severe chemotherapy-induced toxicity: A case series.

EJNMMI research

Predicting the effect of different folate doses on [⁶⁸Ga]Ga-PSMA-11 organ and tumor uptake using physiologically based pharmacokinetic modeling.

15-06-2023

Cancer chemotherapy and pharmacology

Exposure-response analyses of BRAF- and MEK-inhibitors dabrafenib plus trametinib in melanoma patients.

01-06-2023

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

A simple extemporaneous oral suspension of aprepitant yields sufficient pharmacokinetic exposure in children.

01-06-2023

Therapeutic drug monitoring

Development of a Therapeutic Drug Monitoring Strategy for the Optimization of Vincristine Treatment in Pediatric Oncology Populations in Africa.

01-06-2023

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Ion suppression, reduced long-term robustness and leakage current of the spray voltage during the ionization of trichloroacetic acid; a case study with a methylmalonic acid assay.

30-05-2023

Pharmaceutics

Optimization of a Quantitative Anti-Drug Antibodies against Infliximab Assay with the Liquid Chromatography-Tandem Mass Spectrometry: A Method Validation Study and Future Perspectives.

12-05-2023

EClinicalMedicine

Influence of germline variations in drug transporters ABCB1 and ABCG2 on intracerebral osimertinib efficacy in patients with non-small cell lung cancer.

Pharmaceutical research

Exposure-Response Analyses of Olaparib in Real-Life Patients with Ovarian Cancer.

Journal of controlled release : official journal of the Controlled Release Society

Radiosensitisation by olaparib through focused ultrasound delivery in a diffuse midline glioma model.

Haematologica

Combination therapy with crizotinib and vinblastine for relapsed or refractory pediatric ALK-positive anaplastic large cell lymphoma.

Cancer treatment reviews

Clinical development of WEE1 inhibitors in gynecological cancers: A systematic review.

01-04-2023

Frontiers in oncology

Therapeutic drug monitoring guided dosing versus standard dosing of alectinib in advanced ALK positive non-small cell lung cancer patients: Study protocol for an international, multicenter phase IV randomized controlled trial (ADAPT ALEC).

28-03-2023

Journal of pharmaceutical and biomedical analysis

A sensitive liquid chromatographic-mass spectrometry method for the quantification of vincristine in whole blood collected with volumetric absorptive microsampling.

20-02-2023

EJNMMI research

A physiologically based pharmacokinetic model for [⁶⁸Ga]Ga-(HA-)DOTATATE to predict whole-body distribution and tumor sink effects in GEP-NET patients.

03-02-2023

Clinical and translational science

A naïve pooled data approach for extrapolation of Phase 0 microdose trials to therapeutic dosing regimens.

British journal of clinical pharmacology

Prediction of the pharmacokinetics of pemetrexed with a low test dose: A proof-of-concept study.

Anti-cancer drugs

Time above threshold plasma concentrations as pharmacokinetic parameter in the comparison of oral and intravenous docetaxel treatment of breast cancer tumors.

Clinical pharmacology and therapeutics

Prediction of Busulfan Clearance by Predose Plasma Metabolomic Profiling.