Publications

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Systemic exposure of oxaliplatin and docetaxel in gastric cancer patients with peritonitis carcinomatosis treated with intraperitoneal hyperthermic chemotherapy.

01-02-2021

Cancer chemotherapy and pharmacology

Monitoring of EGFR mutations in circulating tumor DNA of non-small cell lung cancer patients treated with EGFR inhibitors.

01-02-2021

The AAPS journal

Population Pharmacokinetics of Intracellular 5-Fluorouridine 5'-Triphosphate and its Relationship with Hand-and-Foot Syndrome in Patients Treated with Capecitabine.

08-01-2021

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Cost-Effectiveness Assessment of Monitoring Abiraterone Levels in Metastatic Castration-Resistant Prostate Cancer Patients.

01-01-2021

Journal of proteome research

Prediction of Acute Graft versus Host Disease and Relapse by Endogenous Metabolomic Compounds in Patients Receiving Personalized Busulfan-Based Conditioning.

01-01-2021

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Reply to: Comments on "Systemic exposure of oxaliplatin and docetaxel in gastric patients with peritonitis carcinomatosis treated with intraperitoneal hyperthermic chemotherapy".

01-12-2020

Clinical pharmacokinetics

Clinical Pharmacokinetics and Pharmacodynamics of the Cyclin-Dependent Kinase 4 and 6 Inhibitors Palbociclib, Ribociclib, and Abemaciclib.

01-12-2020

Journal of clinical medicine

The Predictive Value of Low Skeletal Muscle Mass Assessed on Cross-Sectional Imaging for Anti-Cancer Drug Toxicity: A Systematic Review and Meta-Analysis.

23-11-2020

Clinical pharmacology : advances and applications

Is Bodyweight-Based Dosing Truly Better Than Flat Dosing for Panitumumab? [Letter].

10-11-2020

Clinical pharmacology and therapeutics

Prediction of Drug Exposure in Critically Ill Encephalopathic Neonates Treated With Therapeutic Hypothermia Based on a Pooled Population Pharmacokinetic Analysis of Seven Drugs and Five Metabolites.

01-11-2020

Clinical pharmacology in drug development

Pilot Study to Predict Pharmacokinetics of a Therapeutic Gemcitabine Dose From a Microdose.

01-11-2020

Clinical pharmacokinetics

Early Estimation of Renal Function After Transplantation to Enable Appropriate Dosing of Critical Drugs: Retrospective Analysis of 103 Patients in a Single Center.

01-10-2020

Cancer chemotherapy and pharmacology

Population pharmacokinetic analysis of nanoparticle-bound and free camptothecin after administration of NLG207 in adults with advanced solid tumors.

01-10-2020

The British journal of surgery

Treatment of PERItoneal disease in Stomach Cancer with cytOreductive surgery and hyperthermic intraPEritoneal chemotherapy: PERISCOPE I initial results.

01-10-2020

Bioanalysis

Bottom-up sample preparation for the LC-MS/MS quantification of anti-cancer monoclonal antibodies in bio matrices.

01-10-2020

Investigational new drugs

Quantification of the pharmacokinetic-toxicodynamic relationship of oral docetaxel co-administered with ritonavir.

01-10-2020

European journal of clinical pharmacology

Evaluation of dose-tapering strategies for intravenous tocilizumab in rheumatoid arthritis patients using model-based pharmacokinetic/pharmacodynamic simulations.

01-10-2020

BMJ open

PropAngio study protocol: a neoadjuvant trial on the efficacy of propranolol monotherapy in cutaneous angiosarcoma-a proof of principle study.

10-09-2020

European journal of cancer (Oxford, England : 1990)

Therapeutic drug monitoring of imatinib in patients with gastrointestinal stromal tumours - Results from daily clinical practice.

01-09-2020

Cancer chemotherapy and pharmacology

Cisplatin and carboplatin pharmacokinetics in a pediatric patient with hepatoblastoma receiving peritoneal dialysis.

01-09-2020

Clinical pharmacology and therapeutics

Pharmacokinetic Targets for Therapeutic Drug Monitoring of Small Molecule Kinase Inhibitors in Pediatric Oncology.

01-09-2020

European journal of clinical pharmacology

Determination of the absolute bioavailability of oral imatinib using a stable isotopically labeled intravenous imatinib-d8 microdose.

01-08-2020

Investigational new drugs

Mass balance and metabolite profiling of ¹⁴C-guadecitabine in patients with advanced cancer.

01-08-2020

British journal of clinical pharmacology

A semi-mechanistic model based on glutathione depletion to describe intra-individual reduction in busulfan clearance.

01-08-2020

Therapeutic drug monitoring

Evaluation of Extrapolation Methods to Predict Trough Concentrations to Guide Therapeutic Drug Monitoring of Oral Anticancer Drugs.

01-08-2020

Cancer chemotherapy and pharmacology

Correction to: Exposure-survival analyses of pazopanib in renal cell carcinoma and soft tissue sarcoma patients: opportunities for dose optimization.

01-07-2020

Clinical pharmacokinetics

Cost-Neutral Optimization of Pazopanib Exposure by Splitting Intake Moments: A Prospective Pharmacokinetic Study in Cancer Patients.

01-07-2020

Clinical pharmacokinetics

Population Pharmacokinetics of MCLA-128, a HER2/HER3 Bispecific Monoclonal Antibody, in Patients with Solid Tumors.

01-07-2020

Clinical pharmacokinetics

Unbound Plasma, Total Plasma, and Whole-Blood Tacrolimus Pharmacokinetics Early After Thoracic Organ Transplantation.

01-06-2020

Prostate cancer and prostatic diseases

Exposure-response analyses of abiraterone and its metabolites in real-world patients with metastatic castration-resistant prostate cancer.

01-06-2020

Acta physiologica (Oxford, England)

Doxorubicin-induced skeletal muscle atrophy: Elucidating the underlying molecular pathways.

01-06-2020

Pharmaceutical research

Phase I pharmacological study of continuous chronomodulated capecitabine treatment.

07-05-2020

CPT: pharmacometrics & systems pharmacology

Clinical Trial Simulation To Optimize Trial Design for Fludarabine Dosing Strategies in Allogeneic Hematopoietic Cell Transplantation.

01-05-2020

European journal of cancer (Oxford, England : 1990)

Concomitant intake of abiraterone acetate and food to increase pharmacokinetic exposure: real life data from a therapeutic drug monitoring programme.

01-05-2020

Cancer chemotherapy and pharmacology

Phase I study of lapatinib plus trametinib in patients with KRAS-mutant colorectal, non-small cell lung, and pancreatic cancer.

01-05-2020

British journal of cancer

Phase 1 study of the pan-HER inhibitor dacomitinib plus the MEK1/2 inhibitor PD-0325901 in patients with KRAS-mutation-positive colorectal, non-small-cell lung and pancreatic cancer.

01-04-2020

Clinical pharmacokinetics

Clinical Pharmacokinetics and Impact of Hematocrit on Monitoring and Dosing of Tacrolimus Early After Heart and Lung Transplantation.

01-04-2020

Journal of geriatric oncology

Treatment of older patients with immune checkpoint inhibitors in routine clinical care as compared to inclusion in pivotal registration trials.

01-04-2020

Journal of pharmaceutical and biomedical analysis

Measurement of NLG207 (formerly CRLX101) nanoparticle-bound and released camptothecin in human plasma.

20-03-2020

Journal of clinical pharmacology

A Population Pharmacokinetic Model of Oral Docetaxel Coadministered With Ritonavir to Support Early Clinical Development.

01-03-2020

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

Use of leftovers of monoclonal antibody products after partial extraction - A microbiological safety study.

01-03-2020

The AAPS journal

Quantification of T Cell Binding Polyclonal Rabbit Anti-thymocyte Globulin in Human Plasma with Liquid Chromatography Tandem-Mass Spectrometry.

06-02-2020

European journal of drug metabolism and pharmacokinetics

High Variability of Whole-Blood Tacrolimus Pharmacokinetics Early After Thoracic Organ Transplantation.

01-02-2020

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Development and validation of an integrated LC-MS/MS assay for therapeutic drug monitoring of five PARP-inhibitors.

01-02-2020

Clinical pharmacokinetics

A Semi-Mechanistic Population Pharmacokinetic/Pharmacodynamic Model of Bortezomib in Pediatric Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia.

01-02-2020

British journal of clinical pharmacology

Lidocaine as treatment for neonatal seizures: Evaluation of previously developed population pharmacokinetic models and dosing regimen.

01-01-2020

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation

Predictors for Autoimmune Cytopenias after Allogeneic Hematopoietic Cell Transplantation in Children.

01-01-2020

Pharmaceutical research

Sialic Acid-Engineered IL4-10 Fusion Protein is Bioactive and Rapidly Cleared from the Circulation.

26-12-2019

Pharmacotherapy

Exposure-Response Assessment of Enzalutamide and Its Major Metabolites in a Real-World Cohort of Patients with Metastatic Castration-Resistant Prostate Cancer.

01-12-2019

CPT: pharmacometrics & systems pharmacology

Pharmacokinetics of Capecitabine and Four Metabolites in a Heterogeneous Population of Cancer Patients: A Comprehensive Analysis.

01-12-2019