Publications

Nature communications

Risk stratification and relapse pattern in triple-negative breast cancer with pathological complete response after neoadjuvant treatment: the European GAMBIT real-world study.

24-06-2026

Genome medicine

The contribution of rare germline variants to the immune landscape of breast cancer.

09-05-2026

Histopathology

Making sense of TILs: recommendations for morphological assessment of tumour-infiltrating lymphocytes in gastro-oesophageal carcinoma: A report on behalf of the International Immuno-Oncology Biomarker Working Group.

01-05-2026

Nature communications

Clinicopathologic and molecular predictors of survival in BRCA-deficient tubo-ovarian high-grade serous carcinoma.

01-04-2026

iScience

Compartment-specific tumor-infiltrating immune cells and prognosis in breast cancer.

20-02-2026

The American journal of surgical pathology

Performance Assessment of a Deep Learning-based Algorithm for Ovarian Cancer Histotyping in an Independent Data Set.

01-02-2026

Nature

Fasting boosts breast cancer therapy efficacy via glucocorticoid activation.

01-01-2026

The Lancet. Digital health

Label-efficient computational tumour infiltrating lymphocyte assessment in breast cancer (ECTIL): multicentre validation in 2340 patients with breast cancer.

01-11-2025

Research square

Beyond BRCA deficiency: Clinical and molecular predictors of survival in patients with BRCA-deficient tubo-ovarian high-grade serous carcinoma.

03-10-2025

NPJ digital medicine

H&E to IHC virtual staining methods in breast cancer: an overview and benchmarking.

02-07-2025

Annals of diagnostic pathology

Evaluation of the recently established Dutch nationwide Archipelago of Ovarian Cancer Research biobank.

01-02-2025

Nature medicine

Neoadjuvant nivolumab or nivolumab plus ipilimumab in early-stage triple-negative breast cancer: a phase 2 adaptive trial.

01-11-2024

The oncologist

High expression of phosphoglycerate dehydrogenase predicts poor outcome in patients with high-grade serous ovarian cancer.

06-09-2024

iScience

Predictive gene expression profile for adjuvant taxane benefit in breast cancer in the MATADOR trial.

16-08-2024

British journal of cancer

Tumour microenvironment characterisation to stratify patients for hyperthermic intraperitoneal chemotherapy in high-grade serous ovarian cancer (OVHIPEC-1).

01-08-2024

JAMA oncology

Tumor-Infiltrating Lymphocytes in Patients With Stage I Triple-Negative Breast Cancer Untreated With Chemotherapy.

01-08-2024

NPJ digital medicine

PatchSorter: a high throughput deep learning digital pathology tool for object labeling.

20-06-2024

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

Evaluating the effectiveness of pre-operative diagnosis of ovarian cancer using minimally invasive liquid biopsies by combining serum human epididymis protein 4 and cell-free DNA in patients with an ovarian mass.

06-05-2024

NPJ breast cancer

Tumor-infiltrating lymphocytes in HER2-positive breast cancer treated with neoadjuvant chemotherapy and dual HER2-blockade.

18-04-2024

The Journal of pathology

Image-based multiplex immune profiling of cancer tissues: translational implications. A report of the International Immuno-oncology Biomarker Working Group on Breast Cancer.

01-03-2024

Research square

The prognostic value of tumor-stroma ratio and a newly developed computer-aided quantitative analysis of routine H&E slides in high-grade serous ovarian cancer.

14-11-2023

Cancer cell

CMTM6 shapes antitumor T cell response through modulating protein expression of CD58 and PD-L1.

09-10-2023

Cell reports. Medicine

RadioLOGIC, a healthcare model for processing electronic health records and decision-making in breast disease.

15-08-2023

The Journal of pathology

Spatial analyses of immune cell infiltration in cancer: current methods and future directions: A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer.

01-08-2023

The Journal of pathology

Pitfalls in machine learning-based assessment of tumor-infiltrating lymphocytes in breast cancer: A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer.

01-08-2023

Cancer

CCNE1 and survival of patients with tubo-ovarian high-grade serous carcinoma: An Ovarian Tumor Tissue Analysis consortium study.

01-03-2023

Nature communications

Author Correction: Reversal of pre-existing NGFR-driven tumor and immune therapy resistance.

07-02-2023

Cancers

Homologous Recombination Deficiency and Cyclin E1 Amplification Are Correlated with Immune Cell Infiltration and Survival in High-Grade Serous Ovarian Cancer.

02-12-2022

Gynecologic and obstetric investigation

Establishment of the Dutch Nationwide, Interdisciplinary Infrastructure and Biobank for Fundamental and Translational Ovarian Cancer Research: Archipelago of Ovarian Cancer Research.

01-12-2022

NPJ breast cancer

Deep learning for fully-automated nuclear pleomorphism scoring in breast cancer.

08-11-2022

International journal of cancer

Effect of HIPEC according to HRD/BRCAwt genomic profile in stage III ovarian cancer: Results from the phase III OVHIPEC trial.

15-10-2022

NPJ breast cancer

Spatial interplay of tissue hypoxia and T-cell regulation in ductal carcinoma in situ.

15-09-2022

Cancers

External Quality Assessment 2.0: The Importance of a Standardized Implementation of TILs for Daily and Trial Practices.

02-08-2022

Medical image analysis

DeepSMILE: Contrastive self-supervised pre-training benefits MSI and HRD classification directly from H&E whole-slide images in colorectal and breast cancer.

01-07-2022

NPJ breast cancer

Spatial interplay of lymphocytes and fibroblasts in estrogen receptor-positive HER2-negative breast cancer.

28-04-2022

Virchows Archiv : an international journal of pathology

MCM3 is a novel proliferation marker associated with longer survival for patients with tubo-ovarian high-grade serous carcinoma.

01-04-2022

NPJ breast cancer

The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group.

01-12-2021

NPJ breast cancer

IHC-based Ki67 as response biomarker to tamoxifen in breast cancer window trials enrolling premenopausal women.

20-10-2021

The journal of pathology. Clinical research

Adult-type granulosa cell tumor of the ovary: a FOXL2-centric disease.

01-05-2021

Cancers

A High-Dimensional Window into the Micro-Environment of Triple Negative Breast Cancer.

16-01-2021

Key Publication

Cancer treatment reviews

Erratum to "Prognostic factors in patients with oligometastatic breast cancer - A systematic review". [Cancer treatment Rev. 91 (2020) 102114].

01-01-2021

Virchows Archiv : an international journal of pathology

The effect of the peritoneal tumor microenvironment on invasion of peritoneal metastases of high-grade serous ovarian cancer and the impact of NEOADJUVANT chemotherapy.

01-10-2020

Nature communications

Reversal of pre-existing NGFR-driven tumor and immune therapy resistance.

07-08-2020

Molecular cancer research : MCR

The NF-κB Pathway Promotes Tamoxifen Tolerance and Disease Recurrence in Estrogen Receptor-Positive Breast Cancers.

01-07-2020

NPJ breast cancer

Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer.

16-05-2020

Cancer discovery

Characteristics and Outcome of AKT1^E17K-Mutant Breast Cancer Defined through AACR Project GENIE, a Clinicogenomic Registry.

01-04-2020

Journal of the Endocrine Society

Functional Profiling of FSH and Estradiol in Ovarian Granulosa Cell Tumors.

01-04-2020

Nature medicine

Publisher Correction: Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial.

01-07-2019

Breast cancer research and treatment

Epithelial-to-mesenchymal transition status of primary breast carcinomas and its correlation with metastatic behavior.

01-04-2019

Cell

Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma.

07-02-2019

Risk stratification and relapse pattern in triple-negative breast cancer with pathological complete response after neoadjuvant treatment: the European GAMBIT real-world study.

The contribution of rare germline variants to the immune landscape of breast cancer.

Making sense of TILs: recommendations for morphological assessment of tumour-infiltrating lymphocytes in gastro-oesophageal carcinoma: A report on behalf of the International Immuno-Oncology Biomarker Working Group.

Clinicopathologic and molecular predictors of survival in BRCA-deficient tubo-ovarian high-grade serous carcinoma.

Compartment-specific tumor-infiltrating immune cells and prognosis in breast cancer.

Performance Assessment of a Deep Learning-based Algorithm for Ovarian Cancer Histotyping in an Independent Data Set.

Fasting boosts breast cancer therapy efficacy via glucocorticoid activation.

Label-efficient computational tumour infiltrating lymphocyte assessment in breast cancer (ECTIL): multicentre validation in 2340 patients with breast cancer.

Beyond BRCA deficiency: Clinical and molecular predictors of survival in patients with BRCA-deficient tubo-ovarian high-grade serous carcinoma.

H&E to IHC virtual staining methods in breast cancer: an overview and benchmarking.

Evaluation of the recently established Dutch nationwide Archipelago of Ovarian Cancer Research biobank.

Neoadjuvant nivolumab or nivolumab plus ipilimumab in early-stage triple-negative breast cancer: a phase 2 adaptive trial.

High expression of phosphoglycerate dehydrogenase predicts poor outcome in patients with high-grade serous ovarian cancer.

Predictive gene expression profile for adjuvant taxane benefit in breast cancer in the MATADOR trial.

Tumour microenvironment characterisation to stratify patients for hyperthermic intraperitoneal chemotherapy in high-grade serous ovarian cancer (OVHIPEC-1).

Tumor-Infiltrating Lymphocytes in Patients With Stage I Triple-Negative Breast Cancer Untreated With Chemotherapy.

PatchSorter: a high throughput deep learning digital pathology tool for object labeling.

Evaluating the effectiveness of pre-operative diagnosis of ovarian cancer using minimally invasive liquid biopsies by combining serum human epididymis protein 4 and cell-free DNA in patients with an ovarian mass.

Tumor-infiltrating lymphocytes in HER2-positive breast cancer treated with neoadjuvant chemotherapy and dual HER2-blockade.

Image-based multiplex immune profiling of cancer tissues: translational implications. A report of the International Immuno-oncology Biomarker Working Group on Breast Cancer.

The prognostic value of tumor-stroma ratio and a newly developed computer-aided quantitative analysis of routine H&E slides in high-grade serous ovarian cancer.

CMTM6 shapes antitumor T cell response through modulating protein expression of CD58 and PD-L1.

RadioLOGIC, a healthcare model for processing electronic health records and decision-making in breast disease.

Spatial analyses of immune cell infiltration in cancer: current methods and future directions: A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer.

Pitfalls in machine learning-based assessment of tumor-infiltrating lymphocytes in breast cancer: A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer.

CCNE1 and survival of patients with tubo-ovarian high-grade serous carcinoma: An Ovarian Tumor Tissue Analysis consortium study.

Author Correction: Reversal of pre-existing NGFR-driven tumor and immune therapy resistance.

Homologous Recombination Deficiency and Cyclin E1 Amplification Are Correlated with Immune Cell Infiltration and Survival in High-Grade Serous Ovarian Cancer.

Establishment of the Dutch Nationwide, Interdisciplinary Infrastructure and Biobank for Fundamental and Translational Ovarian Cancer Research: Archipelago of Ovarian Cancer Research.

Deep learning for fully-automated nuclear pleomorphism scoring in breast cancer.

Effect of HIPEC according to HRD/BRCAwt genomic profile in stage III ovarian cancer: Results from the phase III OVHIPEC trial.

Spatial interplay of tissue hypoxia and T-cell regulation in ductal carcinoma in situ.

External Quality Assessment 2.0: The Importance of a Standardized Implementation of TILs for Daily and Trial Practices.

DeepSMILE: Contrastive self-supervised pre-training benefits MSI and HRD classification directly from H&E whole-slide images in colorectal and breast cancer.

Spatial interplay of lymphocytes and fibroblasts in estrogen receptor-positive HER2-negative breast cancer.

MCM3 is a novel proliferation marker associated with longer survival for patients with tubo-ovarian high-grade serous carcinoma.

The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group.

IHC-based Ki67 as response biomarker to tamoxifen in breast cancer window trials enrolling premenopausal women.

Adult-type granulosa cell tumor of the ovary: a FOXL2-centric disease.

A High-Dimensional Window into the Micro-Environment of Triple Negative Breast Cancer.

Erratum to "Prognostic factors in patients with oligometastatic breast cancer - A systematic review". [Cancer treatment Rev. 91 (2020) 102114].

The effect of the peritoneal tumor microenvironment on invasion of peritoneal metastases of high-grade serous ovarian cancer and the impact of NEOADJUVANT chemotherapy.

Reversal of pre-existing NGFR-driven tumor and immune therapy resistance.

The NF-κB Pathway Promotes Tamoxifen Tolerance and Disease Recurrence in Estrogen Receptor-Positive Breast Cancers.

Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer.

Characteristics and Outcome of AKT1E17K-Mutant Breast Cancer Defined through AACR Project GENIE, a Clinicogenomic Registry.

Functional Profiling of FSH and Estradiol in Ovarian Granulosa Cell Tumors.

Publisher Correction: Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial.

Epithelial-to-mesenchymal transition status of primary breast carcinomas and its correlation with metastatic behavior.

Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma.

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Characteristics and Outcome of AKT1^E17K-Mutant Breast Cancer Defined through AACR Project GENIE, a Clinicogenomic Registry.