Publications

Cancer chemotherapy and pharmacology

Assay performance and stability of uracil and dihydrouracil in clinical practice.

01-03-2023

JNCI cancer spectrum

Effects of tamoxifen and exemestane on cognitive function in postmenopausal patients with breast cancer.

01-03-2023

Key

Cardiovascular and interventional radiology

Combining Melphalan Percutaneous Hepatic Perfusion with Ipilimumab Plus Nivolumab in Advanced Uveal Melanoma: First Safety and Efficacy Data from the Phase Ib Part of the Chopin Trial.

01-03-2023

Molecular oncology

More may not be better: reconsidering early clinical trial design in the era of targeted cancer therapeutics.

01-03-2023

European journal of haematology

Comparison of outcomes between Hodgkin's lymphoma patients treated in and outside clinical trials: A study based on the EORTC-Dutch late effects cohort-linked data.

01-03-2023

Current opinion in oncology

Novel strategies to improve efficacy of treatment with tumor-infiltrating lymphocytes (TILs) for patients with solid cancers.

01-03-2023

Clinical and translational radiation oncology

Study protocol: PreOperative Brain Irradiation in Glioblastoma (POBIG) - A phase I trial.

01-03-2023

Cancer medicine

Questionnaire- and linkage-based outcomes in Dutch childhood cancer survivors: Methodology of the DCCSS LATER study part 1.

01-03-2023

Clinical cancer research : an official journal of the American Association for Cancer Research

Metastatic Colorectal Cancer Treatment Response Evaluation by Ultra-Deep Sequencing of Cell-Free DNA and Matched White Blood Cells.

01-03-2023

Nature reviews. Drug discovery

Rational combinations of targeted cancer therapies: background, advances and challenges.

01-03-2023

European journal of cancer (Oxford, England : 1990)

EBCC-13 manifesto: Balancing pros and cons for contralateral prophylactic mastectomy.

01-03-2023

European urology open science

Genetic Aspects and Molecular Testing in Prostate Cancer: A Report from a Dutch Multidisciplinary Consensus Meeting.

01-03-2023

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Initial Impact of National CRC Screening on Incidence and Advanced Colorectal Cancer.

01-03-2023

British journal of cancer

Risk of ovarian cancer in women who give birth after assisted reproductive technology (ART)-a registry-based Nordic cohort study with follow-up from first pregnancy.

01-03-2023

European urology open science

Sentinel Node Procedure to Select Clinically Localized Prostate Cancer Patients with Occult Nodal Metastases for Whole Pelvis Radiotherapy.

01-03-2023

Cancers

The Tumor Coagulome as a Transcriptional Target and a Potential Effector of Glucocorticoids in Human Cancers.

28-02-2023

Cancers

Trends in Incidence and Survival of 1496 Patients with Mucosal Melanoma in The Netherlands (1990-2019).

28-02-2023

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Are gastrointestinal problems, nutritional care, and nutritional care needs associated with quality of life in patients with advanced cancer? Results of the observational eQuiPe study.

27-02-2023

Nucleic acids research

Unexpected moves: a conformational change in MutSα enables high-affinity DNA mismatch binding.

22-02-2023

Cell reports. Medicine

Genetic screens reveal new targetable vulnerabilities in BAP1-deficient mesothelioma.

21-02-2023

Cell reports. Medicine

An adverse tumor-protective effect of IDO1 inhibition.

21-02-2023

Journal of pharmaceutical and biomedical analysis

A sensitive liquid chromatographic-mass spectrometry method for the quantification of vincristine in whole blood collected with volumetric absorptive microsampling.

20-02-2023

The British journal of surgery

Predicting early extrahepatic recurrence after local treatment of colorectal liver metastases.

15-02-2023

Frontiers in oncology

Dose accumulation for MR-guided adaptive radiotherapy: From practical considerations to state-of-the-art clinical implementation.

14-02-2023

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Perception of prognosis and health-related quality of life in patients with advanced cancer: results of a multicentre observational study (eQuiPe).

13-02-2023

Cancer cell

Base editing screens map mutations affecting interferon-γ signaling in cancer.

13-02-2023

Nature communications

Author Correction: Reversal of pre-existing NGFR-driven tumor and immune therapy resistance.

07-02-2023

Cancers

Online Adaptive MRI-Guided Radiotherapy for Primary Tumor and Lymph Node Boosting in Rectal Cancer.

05-02-2023

International journal of molecular sciences

Triple-Negative Breast Cancer and Predictive Markers of Response to Neoadjuvant Chemotherapy: A Systematic Review.

03-02-2023

BMC bioinformatics

ShrinkCRISPR: a flexible method for differential fitness analysis of CRISPR-Cas9 screen data.

03-02-2023

EJNMMI research

A physiologically based pharmacokinetic model for [⁶⁸Ga]Ga-(HA-)DOTATATE to predict whole-body distribution and tumor sink effects in GEP-NET patients.

03-02-2023

Nature communications

Deletion of SNX9 alleviates CD8 T cell exhaustion for effective cellular cancer immunotherapy.

02-02-2023

Molecular cell

Proteome diversification by mRNA translation in cancer.

02-02-2023

European radiology

Safety and efficacy of RFA versus MWA for T1a renal cell carcinoma: a propensity score analysis.

01-02-2023

Nature cancer

A reversible SRC-relayed COX2 inflammatory program drives resistance to BRAF and EGFR inhibition in BRAF^V600E colorectal tumors.

01-02-2023

Melanoma research

Talimogene laherparepvec monotherapy for head and neck melanoma patients.

01-02-2023

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

The role of ESTRO guidelines in achieving consistency and quality in clinical radiation oncology practice.

01-02-2023

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

Endoscopy and MRI for restaging early rectal cancer after neoadjuvant treatment.

01-02-2023

Cancer treatment reviews

Mechanisms of resistance to immune checkpoint inhibitors in melanoma: What we have to overcome?

01-02-2023

Future oncology (London, England)

A patient's perspective on the side effects of tyrosine kinase inhibitors in the treatment of advanced and metastatic gastrointestinal stromal tumors.

01-02-2023

Acta radiologica (Stockholm, Sweden : 1987)

Pelvic CT in addition to MRI to differentiate between rectal and sigmoid cancer on imaging using the sigmoid take-off as a landmark.

01-02-2023

ESMO open

One-year data on immunogenicity and breakthrough infections in patients with solid tumors vaccinated against COVID-19 during systemic cancer treatment.

01-02-2023

Nature

Single-cell spatial immune landscapes of primary and metastatic brain tumours.

01-02-2023

Nature methods

AlphaFill: enriching AlphaFold models with ligands and cofactors.

01-02-2023

Journal of robotic surgery

Click-on fluorescence detectors: using robotic surgical instruments to characterize molecular tissue aspects.

01-02-2023

Clinical and translational science

A naïve pooled data approach for extrapolation of Phase 0 microdose trials to therapeutic dosing regimens.

01-02-2023

Urologic oncology

Predictive value of low testosterone concentrations during and prior to enzalutamide treatment in metastatic castration-resistant prostate cancer.

01-02-2023

British journal of clinical pharmacology

Prediction of the pharmacokinetics of pemetrexed with a low test dose: A proof-of-concept study.

01-02-2023

Anti-cancer drugs

Time above threshold plasma concentrations as pharmacokinetic parameter in the comparison of oral and intravenous docetaxel treatment of breast cancer tumors.

01-02-2023

Cancer medicine

Risk of metachronous contralateral breast cancer in patients with primary invasive lobular breast cancer: Results from a nationwide cohort.

01-02-2023