How do cancer and the immune system interact?
The human body constantly cleans up the abnormal cells found in our bodies. Cancer cells can circumvent this system, however. How do they accomplish that?
In short, they change their environment in all sorts of ways to accommodate their survival, division, and metastasis. This requires them to exchange information with the surrounding cells, including immune cells. We investigate the ways in which this works, and whether we can potentially block the support that cancer cells extract from their environments.