Digital image analysis of B cells and T cells in tertiary lymphoid structures in human lung cancer

Daniela Thommen

Precision cancer immunotherapy

Immunotherapy has revolutionized cancer treatment and is now used for many cancer types. However, not all patients benefit yet from this therapy. As a tool to investigate the effects of immunotherapy outside of the patient, our group develops patient-derived organotypic tumor models. Using these models, we study how tumor immune composition and architecture influence immunotherapy responses and how distinct treatments can alter immune activity in a tumor.

Our ultimate goal is to contribute to the development of personalized immunotherapies by identifying new biomarkers or treatment strategies.

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