Publications

Cancer discovery

CD8-targeted IL2 unleashes tumor-specific immunity in human cancer tissue by reviving the dysfunctional T cell pool.

02-04-2024

Clinical cancer research : an official journal of the American Association for Cancer Research

A Dysfunctional T-cell Gene Signature for Predicting Nonresponse to PD-1 Blockade in Non-small Cell Lung Cancer That Is Suitable for Routine Clinical Diagnostics.

16-02-2024

Cancer discovery

Dual Immune Checkpoint Blockade Induces Analogous Alterations in the Dysfunctional CD8+ T-cell and Activated Treg Compartment.

05-10-2023

Nature cancer

Interleukin 17 signaling supports clinical benefit of dual CTLA-4 and PD-1 checkpoint inhibition in melanoma.

01-09-2023

Nature cancer

Author Correction: Interleukin 17 signaling supports clinical benefit of dual CTLA-4 and PD-1 checkpoint inhibition in melanoma.

01-09-2023

STAR protocols

Protocol for ex vivo culture of patient-derived tumor fragments.

06-05-2023

Nature communications

Deletion of SNX9 alleviates CD8 T cell exhaustion for effective cellular cancer immunotherapy.

02-02-2023

Cancer cell

IL-5-producing CD4⁺ T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer.

09-01-2023

Nature reviews. Cancer

Tumour avatars to model patients' responses to immunotherapy.

01-12-2022

Clinical cancer research : an official journal of the American Association for Cancer Research

PD-1T TILs as a Predictive Biomarker for Clinical Benefit to PD-1 Blockade in Patients with Advanced NSCLC.

14-11-2022

Nature cancer

Keeping track of the T cells that matter.

01-09-2022

Science translational medicine

NK cells with tissue-resident traits shape response to immunotherapy by inducing adaptive antitumor immunity.

13-07-2022

Immuno-oncology technology

Multimodal predictors for precision immunotherapy.

01-06-2022

Science translational medicine

Addition of interleukin-2 overcomes resistance to neoadjuvant CTLA4 and PD1 blockade in ex vivo patient tumors.

27-04-2022

Science (New York, N.Y.)

Tertiary lymphoid structures in cancer.

07-01-2022

Nature chemical biology

Single-cell analysis of regions of interest (SCARI) using a photosensitive tag.

01-11-2021

Cancer immunology research

Supporting the Next Generation of Scientists to Lead Cancer Immunology Research.

01-11-2021

Cancer discovery

Anti-Inflammatory Drugs Remodel the Tumor Immune Environment to Enhance Immune Checkpoint Blockade Efficacy.

01-10-2021

Nature medicine

An ex vivo tumor fragment platform to dissect response to PD-1 blockade in cancer.

01-07-2021

Immuno-oncology technology

Integrated functional and spatial profiling of tumour immune responses induced by immunotherapy: the iPROFILER platform.

01-06-2021

Journal for immunotherapy of cancer

Rationalizing the pathway to personalized neoadjuvant immunotherapy: the Lombard Street Approach.

01-08-2020

Nature cancer

Publisher Correction: Long-distance modulation of bystander tumor cells by CD8⁺ T-cell-secreted IFN-γ.

01-07-2020

Journal for immunotherapy of cancer

Fibroblast activation protein-targeted-4-1BB ligand agonist amplifies effector functions of intratumoral T cells in human cancer.

01-07-2020

Nature reviews. Cancer

CD8⁺ T cell states in human cancer: insights from single-cell analysis.

01-04-2020

Nature cancer

Long-distance modulation of bystander tumor cells by CD8⁺ T cell-secreted IFNγ.

01-03-2020

Clinical cancer research : an official journal of the American Association for Cancer Research

A Variant of a Killer Cell Immunoglobulin-like Receptor Is Associated with Resistance to PD-1 Blockade in Lung Cancer.

15-05-2019

Immunity

The First Shall (Be) Last: Understanding Durable T Cell Responses in Immunotherapy.

15-01-2019

Histopathology

Digital image analysis improves precision of PD-L1 scoring in cutaneous melanoma.

01-09-2018

Nature medicine

A transcriptionally and functionally distinct PD-1⁺ CD8⁺ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade.

01-07-2018

Cancer cell

T Cell Dysfunction in Cancer.

09-04-2018