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Wout Oosterheert

Mechanistic structural biology

Proteins are essential molecules that perform virtually every function within the cell. Our group aims to uncover the 3D-structures of protein complexes. This enables us to understand how our cells operate at the atomic level. 

We are particularly interested in the mechanisms that underlie (cancer)-cell migration and adhesion. Specifically, we study how the cytoskeleton interacts with the cell membrane using a combination of cryo-electron microscopy and biophysical methods. Our research is driven by curiosity, but may ultimately also contribute to the development of novel anti-cancer drugs. 


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