Publications

Gut

CDK12 inhibition mediates DNA damage and is synergistic with sorafenib treatment in hepatocellular carcinoma.

01-04-2020

ESMO open

Preferences to receive unsolicited findings of germline genome sequencing in a large population of patients with cancer.

01-04-2020

JAMA oncology

High-Dose Chemotherapy With Hematopoietic Stem Cell Transplant in Patients With High-Risk Breast Cancer and 4 or More Involved Axillary Lymph Nodes: 20-Year Follow-up of a Phase 3 Randomized Clinical Trial.

01-04-2020

Molecular oncology

Somatic mutations and copy number variations in breast cancers with heterogeneous HER2 amplification.

01-04-2020

Physics and imaging in radiation oncology

Accurate estimation of daily delivered radiotherapy dose with an external treatment planning system.

01-04-2020

Clinical & experimental metastasis

Poor perfusion of the microvasculature in peritoneal metastases of ovarian cancer.

01-04-2020

Breast (Edinburgh, Scotland)

The impact of patient characteristics and lifestyle factors on the risk of an ipsilateral event after a primary DCIS: A systematic review.

01-04-2020

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Prostate-Specific Membrane Antigen PET/CT Combined with Sentinel Node Biopsy for Primary Lymph Node Staging in Prostate Cancer.

01-04-2020

The Journal of pathology

The path to a better biomarker: application of a risk management framework for the implementation of PD-L1 and TILs as immuno-oncology biomarkers in breast cancer clinical trials and daily practice.

01-04-2020

The British journal of oral & maxillofacial surgery

Ultrasound aids in intraoperative assessment of deep resection margins of squamous cell carcinoma of the tongue.

01-04-2020

Annals of oncology : official journal of the European Society for Medical Oncology

Efficacy of chemotherapy and atezolizumab in patients with non-small-cell lung cancer receiving antibiotics and proton pump inhibitors: pooled post hoc analyses of the OAK and POPLAR trials.

01-04-2020

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

MRI predicts increased eligibility for sphincter preservation after CRT in low rectal cancer.

01-04-2020

The oncologist

The EORTC QLQ-C30 Summary Score as Prognostic Factor for Survival of Patients with Cancer in the "Real-World": Results from the Population-Based PROFILES Registry.

01-04-2020

Annals of oncology : official journal of the European Society for Medical Oncology

Corrigendum to An international update of the EORTC questionnaire for assessing quality of life in breast cancer patients: EORTC QLQ-BR45: Ann Oncol 2020; Volume 31, Issue 2, Pages 283-288.

01-04-2020

Cancer research

Truncated ASPP2 Drives Initiation and Progression of Invasive Lobular Carcinoma via Distinct Mechanisms.

01-04-2020

Nature communications

Publisher Correction: A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA.

31-03-2020

Insights into imaging

Women in focus: advice from the front lines on how to enable well-being and build resilience.

30-03-2020

Proceedings of the National Academy of Sciences of the United States of America

CD29 identifies IFN-γ-producing human CD8⁺ T cells with an increased cytotoxic potential.

24-03-2020

Developmental cell

Phosphorylated Lamins in Euchromatin: New Clues to Progeria.

23-03-2020

Developmental cell

WAPL-Dependent Repair of Damaged DNA Replication Forks Underlies Oncogene-Induced Loss of Sister Chromatid Cohesion.

23-03-2020

Oncoimmunology

Response and survival of metastatic melanoma patients treated with immune checkpoint inhibition for recurrent disease on adjuvant dendritic cell vaccination.

22-03-2020

Journal of pharmaceutical and biomedical analysis

Measurement of NLG207 (formerly CRLX101) nanoparticle-bound and released camptothecin in human plasma.

20-03-2020

Cancers

Gastrointestinal Stromal Tumours (GIST) in Young Adult (18-40 Years) Patients: A Report from the Dutch GIST Registry.

20-03-2020

Nature communications

Degree and site of chromosomal instability define its oncogenic potential.

20-03-2020

Cell reports

FGFR1 Oncogenic Activation Reveals an Alternative Cell of Origin of SCLC in Rb1/p53 Mice.

17-03-2020

The EMBO journal

Local rewiring of genome-nuclear lamina interactions by transcription.

16-03-2020

International journal of cancer

P-glycoprotein (MDR1/ABCB1) controls brain accumulation and intestinal disposition of the novel TGF-β signaling pathway inhibitor galunisertib.

15-03-2020

PloS one

Approximating multivariate posterior distribution functions from Monte Carlo samples for sequential Bayesian inference.

14-03-2020

BMC medical informatics and decision making

Development and internal validation of prediction models for colorectal cancer survivors to estimate the 1-year risk of low health-related quality of life in multiple domains.

12-03-2020

Oncoimmunology

Lactate dehydrogenase: a marker of diminished antitumor immunity.

12-03-2020

Frontiers in oncology

Hippocampus-Related Cognitive and Affective Impairments in Patients With Breast Cancer-A Systematic Review.

11-03-2020

Scientific reports

Privacy-preserving distributed learning of radiomics to predict overall survival and HPV status in head and neck cancer.

11-03-2020

Frontiers in chemistry

Strategy for Development of Site-Specific Ubiquitin Antibodies.

11-03-2020

Physical therapy

Education Needs of Dutch Physical Therapists for the Treatment of Patients With Advanced Cancer: A Mixed Methods Study.

10-03-2020

Frontiers in oncology

Preclinical Models of Malignant Mesothelioma.

03-03-2020

Oncoimmunology

Response of metastatic mouse invasive lobular carcinoma to mTOR inhibition is partly mediated by the adaptive immune system.

03-03-2020

The EMBO journal

In situ CRISPR-Cas9 base editing for the development of genetically engineered mouse models of breast cancer.

02-03-2020

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Consistency matters: measurement invariance of the EORTC QLQ-C30 questionnaire in patients with hematologic malignancies.

01-03-2020

Journal of neuropathology and experimental neurology

Expression and Cellular Distribution of P-Glycoprotein and Breast Cancer Resistance Protein in Amyotrophic Lateral Sclerosis Patients.

01-03-2020

Medical physics

Erratum: "Investigating the impact of patient arm position in an MR-linac on liver SBRT treatment plans" [Med. Phys. Vol 46, 5144-5151 (2019)].

01-03-2020

Biochemistry and biophysics reports

Biochemical characterization of TRIM72 E3 ligase and its interaction with the insulin receptor substrate 1.

01-03-2020

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)

A Deep Learning-based correction to EPID dosimetry for attenuation and scatter in the Unity MR-Linac system.

01-03-2020

Current opinion in urology

Management of the penile squamous cell carcinoma patient after node positive radical inguinal lymph node dissection: current evidence and future prospects.

01-03-2020

Psycho-oncology

Risk factors of unmet needs among women with breast cancer in the post-treatment phase.

01-03-2020

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Is watch and wait a safe and effective way to treat rectal cancer in older patients?

01-03-2020

European journal of endocrinology

The effect of treatment on quality of life in patients with acromegaly: a prospective study.

01-03-2020

Pigment cell & melanoma research

A genome-wide CRISPR screen identifies FBXO42 involvement in resistance toward MEK inhibition in NRAS-mutant melanoma.

01-03-2020

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Nationwide analysis of hospital variation in preoperative radiotherapy use for rectal cancer following guideline revision.

01-03-2020

Nature

Chromatin modified in a molecular reaction chamber.

01-03-2020

BJU international

The risk of developing cardiovascular disease is increased for patients with prostate cancer who are pharmaceutically treated for depression.

01-03-2020

CDK12 inhibition mediates DNA damage and is synergistic with sorafenib treatment in hepatocellular carcinoma.

Preferences to receive unsolicited findings of germline genome sequencing in a large population of patients with cancer.

High-Dose Chemotherapy With Hematopoietic Stem Cell Transplant in Patients With High-Risk Breast Cancer and 4 or More Involved Axillary Lymph Nodes: 20-Year Follow-up of a Phase 3 Randomized Clinical Trial.

Somatic mutations and copy number variations in breast cancers with heterogeneous HER2 amplification.

Accurate estimation of daily delivered radiotherapy dose with an external treatment planning system.

Poor perfusion of the microvasculature in peritoneal metastases of ovarian cancer.

The impact of patient characteristics and lifestyle factors on the risk of an ipsilateral event after a primary DCIS: A systematic review.

Prostate-Specific Membrane Antigen PET/CT Combined with Sentinel Node Biopsy for Primary Lymph Node Staging in Prostate Cancer.

The path to a better biomarker: application of a risk management framework for the implementation of PD-L1 and TILs as immuno-oncology biomarkers in breast cancer clinical trials and daily practice.

Ultrasound aids in intraoperative assessment of deep resection margins of squamous cell carcinoma of the tongue.

Efficacy of chemotherapy and atezolizumab in patients with non-small-cell lung cancer receiving antibiotics and proton pump inhibitors: pooled post hoc analyses of the OAK and POPLAR trials.

MRI predicts increased eligibility for sphincter preservation after CRT in low rectal cancer.

The EORTC QLQ-C30 Summary Score as Prognostic Factor for Survival of Patients with Cancer in the "Real-World": Results from the Population-Based PROFILES Registry.

Corrigendum to An international update of the EORTC questionnaire for assessing quality of life in breast cancer patients: EORTC QLQ-BR45: Ann Oncol 2020; Volume 31, Issue 2, Pages 283-288.

Truncated ASPP2 Drives Initiation and Progression of Invasive Lobular Carcinoma via Distinct Mechanisms.

Publisher Correction: A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA.

Women in focus: advice from the front lines on how to enable well-being and build resilience.

CD29 identifies IFN-γ-producing human CD8+ T cells with an increased cytotoxic potential.

Phosphorylated Lamins in Euchromatin: New Clues to Progeria.

WAPL-Dependent Repair of Damaged DNA Replication Forks Underlies Oncogene-Induced Loss of Sister Chromatid Cohesion.

Response and survival of metastatic melanoma patients treated with immune checkpoint inhibition for recurrent disease on adjuvant dendritic cell vaccination.

Measurement of NLG207 (formerly CRLX101) nanoparticle-bound and released camptothecin in human plasma.

Gastrointestinal Stromal Tumours (GIST) in Young Adult (18-40 Years) Patients: A Report from the Dutch GIST Registry.

Degree and site of chromosomal instability define its oncogenic potential.

FGFR1 Oncogenic Activation Reveals an Alternative Cell of Origin of SCLC in Rb1/p53 Mice.

Local rewiring of genome-nuclear lamina interactions by transcription.

P-glycoprotein (MDR1/ABCB1) controls brain accumulation and intestinal disposition of the novel TGF-β signaling pathway inhibitor galunisertib.

Approximating multivariate posterior distribution functions from Monte Carlo samples for sequential Bayesian inference.

Development and internal validation of prediction models for colorectal cancer survivors to estimate the 1-year risk of low health-related quality of life in multiple domains.

Lactate dehydrogenase: a marker of diminished antitumor immunity.

Hippocampus-Related Cognitive and Affective Impairments in Patients With Breast Cancer-A Systematic Review.

Privacy-preserving distributed learning of radiomics to predict overall survival and HPV status in head and neck cancer.

Strategy for Development of Site-Specific Ubiquitin Antibodies.

Education Needs of Dutch Physical Therapists for the Treatment of Patients With Advanced Cancer: A Mixed Methods Study.

Preclinical Models of Malignant Mesothelioma.

Response of metastatic mouse invasive lobular carcinoma to mTOR inhibition is partly mediated by the adaptive immune system.

In situ CRISPR-Cas9 base editing for the development of genetically engineered mouse models of breast cancer.

Consistency matters: measurement invariance of the EORTC QLQ-C30 questionnaire in patients with hematologic malignancies.

Expression and Cellular Distribution of P-Glycoprotein and Breast Cancer Resistance Protein in Amyotrophic Lateral Sclerosis Patients.

Erratum: "Investigating the impact of patient arm position in an MR-linac on liver SBRT treatment plans" [Med. Phys. Vol 46, 5144-5151 (2019)].

Biochemical characterization of TRIM72 E3 ligase and its interaction with the insulin receptor substrate 1.

A Deep Learning-based correction to EPID dosimetry for attenuation and scatter in the Unity MR-Linac system.

Management of the penile squamous cell carcinoma patient after node positive radical inguinal lymph node dissection: current evidence and future prospects.

Risk factors of unmet needs among women with breast cancer in the post-treatment phase.

Is watch and wait a safe and effective way to treat rectal cancer in older patients?

The effect of treatment on quality of life in patients with acromegaly: a prospective study.

A genome-wide CRISPR screen identifies FBXO42 involvement in resistance toward MEK inhibition in NRAS-mutant melanoma.

Nationwide analysis of hospital variation in preoperative radiotherapy use for rectal cancer following guideline revision.

Chromatin modified in a molecular reaction chamber.

The risk of developing cardiovascular disease is increased for patients with prostate cancer who are pharmaceutically treated for depression.

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CD29 identifies IFN-γ-producing human CD8⁺ T cells with an increased cytotoxic potential.