Publications

Molecular & cellular proteomics : MCP

Combined EGFR and ROCK Inhibition in Triple-negative Breast Cancer Leads to Cell Death Via Impaired Autophagic Flux.

01-02-2020

Nature cancer

Old drugs with new tricks.

01-02-2020

Clinical genitourinary cancer

Survival Outcomes From a Cumulative Analysis of Worldwide Observational Studies on Sequential Use of New Agents in Metastatic Castration-Resistant Prostate Cancer.

01-02-2020

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Health-related quality of life in adult patients with brain metastases after stereotactic radiosurgery: a systematic, narrative review.

01-02-2020

International journal of computer assisted radiology and surgery

Accuracy assessment of target tracking using two 5-degrees-of-freedom wireless transponders.

01-02-2020

International journal of computer assisted radiology and surgery

Differentiating benign and malignant mass and non-mass lesions in breast DCE-MRI using normalized frequency-based features.

01-02-2020

The Journal of pathology

BTK inhibitors synergise with 5-FU to treat drug-resistant TP53-null colon cancers.

01-02-2020

Nature

The structural basis for cohesin-CTCF-anchored loops.

01-02-2020

Molecular cancer therapeutics

Functional Genomic Screen in Mesothelioma Reveals that Loss of Function of BRCA1-Associated Protein 1 Induces Chemoresistance to Ribonucleotide Reductase Inhibition.

01-02-2020

Annals of oncology : official journal of the European Society for Medical Oncology

An international update of the EORTC questionnaire for assessing quality of life in breast cancer patients: EORTC QLQ-BR45.

01-02-2020

Cancer research

Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness.

01-02-2020

European urology

Clinical outcome after progressing to frontline and second-line Anti-PD-1/PD-L1 in advanced urothelial cancer.

01-02-2020

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Local and regional treatment response by ¹⁸FDG-PET-CT-scans 4 weeks after concurrent hypofractionated chemoradiotherapy in locally advanced NSCLC.

01-02-2020

Methods in enzymology

In vitro assessment of cancer cell-induced polarization of macrophages.

01-02-2020

European journal of heart failure

Heart failure after treatment for breast cancer.

01-02-2020

Clinical pharmacokinetics

A Semi-Mechanistic Population Pharmacokinetic/Pharmacodynamic Model of Bortezomib in Pediatric Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia.

01-02-2020

Endocrine-related cancer

Androgen modulation of XBP1 is functionally driving part of the AR transcriptional program.

01-02-2020

Frontiers in oncology

Biological Determinants of Chemo-Radiotherapy Response in HPV-Negative Head and Neck Cancer: A Multicentric External Validation.

31-01-2020

Aesthet Surg J

Breast Implant Prevalence in the Dutch Female Population Assessed by Chest Radiographs

29-01-2020

Aesthetic surgery journal

Breast Implant Prevalence in the Dutch Female Population Assessed by Chest Radiographs.

29-01-2020

Nature communications

White blood cell and cell-free DNA analyses for detection of residual disease in gastric cancer.

27-01-2020

Nature communications

Noncoding mutations target cis-regulatory elements of the FOXA1 plexus in prostate cancer.

23-01-2020

Radiology and oncology

Sequential intra-arterial infusion of 90Y-resin microspheres and mitomycin C in chemo refractory liver metastatic breast cancer patients: a single centre pilot study.

21-01-2020

Breast cancer research : BCR

Risk-reducing salpingo-oophorectomy, natural menopause, and breast cancer risk: an international prospective cohort of BRCA1 and BRCA2 mutation carriers.

16-01-2020

Nature communications

A network analysis to identify mediators of germline-driven differences in breast cancer prognosis.

16-01-2020

Key Publication

Cancer

Changes in internet use and wishes of cancer survivors: A comparison between 2005 and 2017.

15-01-2020

Trials

Evaluating a digital tool for supporting breast cancer patients: a randomized controlled trial protocol (ADAPT).

15-01-2020

Neuro-oncology

A pilot randomized controlled trial of exercise to improve cognitive performance in patients with stable glioma: a proof of concept.

11-01-2020

Neuro-oncology

MEK/MELK inhibition and blood-brain barrier deficiencies in atypical teratoid/rhabdoid tumors.

11-01-2020

Journal of clinical medicine

Diagnostic Accuracy of Stool Tests for Colorectal Cancer Surveillance in Hodgkin Lymphoma Survivors.

10-01-2020

EMBO reports

PHF6 promotes non-homologous end joining and G2 checkpoint recovery.

07-01-2020

Nature

The structural basis for cohesin–CTCF-anchored loops

06-01-2020

Inflammatory bowel diseases

IBD-Associated Dysplastic Lesions Show More Chromosomal Instability Than Sporadic Adenomas.

06-01-2020

International journal of pharmaceutics

P-glycoprotein (ABCB1/MDR1) limits brain accumulation and Cytochrome P450-3A (CYP3A) restricts oral availability of the novel FGFR4 inhibitor fisogatinib (BLU-554).

05-01-2020

Journal of pharmaceutical and biomedical analysis

Bioanalysis of EGFRm inhibitor osimertinib, and its glutathione cycle- and desmethyl metabolites by liquid chromatography-tandem mass spectrometry.

05-01-2020

Clinical oncology (Royal College of Radiologists (Great Britain))

Embryonal and Alveolar Rhabdomyosarcoma in Adults: Real-Life Data From a Tertiary Sarcoma Centre.

01-01-2020

Journal of cell science

Sequence-dependent trafficking and activity of GDE2, a GPI-specific phospholipase promoting neuronal differentiation.

01-01-2020

Future oncology (London, England)

ENERGIZE: a Phase III study of neoadjuvant chemotherapy alone or with nivolumab with/without linrodostat mesylate for muscle-invasive bladder cancer.

01-01-2020

Annals of oncology : official journal of the European Society for Medical Oncology

Elevated baseline serum PD-1 or PD-L1 predicts poor outcome of PD-1 inhibition therapy in metastatic melanoma.

01-01-2020

Biomedical chromatography : BMC

Bioanalytical LC-MS/MS validation of therapeutic drug monitoring assays in oncology.

01-01-2020

Nature genetics

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes.

01-01-2020

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Prostate-Specific Membrane Antigen-Guided Surgery.

01-01-2020

European journal of cancer care

The "Psychosocial Aspects in Hereditary Cancer" questionnaire in women attending breast cancer genetic clinics: Psychometric validation across French-, German- and Spanish-language versions.

01-01-2020

British journal of clinical pharmacology

Lidocaine as treatment for neonatal seizures: Evaluation of previously developed population pharmacokinetic models and dosing regimen.

01-01-2020

Nature protocols

Tumor organoid-T-cell coculture systems.

01-01-2020

Nature cancer

A roadmap for the next decade in cancer research.

01-01-2020

Annals of oncology : official journal of the European Society for Medical Oncology

Cognitive behavioral therapy or graded exercise therapy compared with usual care for severe fatigue in patients with advanced cancer during treatment: a randomized controlled trial.

01-01-2020

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Diffusion-weighted MRI with ADC mapping for response prediction and assessment of oesophageal cancer: A systematic review.

01-01-2020

Maturitas

Internet-based cognitive behavioral therapy aimed at alleviating treatment-induced menopausal symptoms in breast cancer survivors: Moderators and mediators of treatment effects.

01-01-2020

Annals of oncology : official journal of the European Society for Medical Oncology

Multicenter randomized controlled trial to evaluate the efficacy and tolerability of frozen gloves for the prevention of chemotherapy-induced peripheral neuropathy.

01-01-2020

Combined EGFR and ROCK Inhibition in Triple-negative Breast Cancer Leads to Cell Death Via Impaired Autophagic Flux.

Old drugs with new tricks.

Survival Outcomes From a Cumulative Analysis of Worldwide Observational Studies on Sequential Use of New Agents in Metastatic Castration-Resistant Prostate Cancer.

Health-related quality of life in adult patients with brain metastases after stereotactic radiosurgery: a systematic, narrative review.

Accuracy assessment of target tracking using two 5-degrees-of-freedom wireless transponders.

Differentiating benign and malignant mass and non-mass lesions in breast DCE-MRI using normalized frequency-based features.

BTK inhibitors synergise with 5-FU to treat drug-resistant TP53-null colon cancers.

The structural basis for cohesin-CTCF-anchored loops.

Functional Genomic Screen in Mesothelioma Reveals that Loss of Function of BRCA1-Associated Protein 1 Induces Chemoresistance to Ribonucleotide Reductase Inhibition.

An international update of the EORTC questionnaire for assessing quality of life in breast cancer patients: EORTC QLQ-BR45.

Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness.

Clinical outcome after progressing to frontline and second-line Anti-PD-1/PD-L1 in advanced urothelial cancer.

Local and regional treatment response by 18FDG-PET-CT-scans 4 weeks after concurrent hypofractionated chemoradiotherapy in locally advanced NSCLC.

In vitro assessment of cancer cell-induced polarization of macrophages.

Heart failure after treatment for breast cancer.

A Semi-Mechanistic Population Pharmacokinetic/Pharmacodynamic Model of Bortezomib in Pediatric Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia.

Androgen modulation of XBP1 is functionally driving part of the AR transcriptional program.

Biological Determinants of Chemo-Radiotherapy Response in HPV-Negative Head and Neck Cancer: A Multicentric External Validation.

Breast Implant Prevalence in the Dutch Female Population Assessed by Chest Radiographs

Breast Implant Prevalence in the Dutch Female Population Assessed by Chest Radiographs.

White blood cell and cell-free DNA analyses for detection of residual disease in gastric cancer.

Noncoding mutations target cis-regulatory elements of the FOXA1 plexus in prostate cancer.

Sequential intra-arterial infusion of 90Y-resin microspheres and mitomycin C in chemo refractory liver metastatic breast cancer patients: a single centre pilot study.

Risk-reducing salpingo-oophorectomy, natural menopause, and breast cancer risk: an international prospective cohort of BRCA1 and BRCA2 mutation carriers.

A network analysis to identify mediators of germline-driven differences in breast cancer prognosis.

Changes in internet use and wishes of cancer survivors: A comparison between 2005 and 2017.

Evaluating a digital tool for supporting breast cancer patients: a randomized controlled trial protocol (ADAPT).

A pilot randomized controlled trial of exercise to improve cognitive performance in patients with stable glioma: a proof of concept.

MEK/MELK inhibition and blood-brain barrier deficiencies in atypical teratoid/rhabdoid tumors.

Diagnostic Accuracy of Stool Tests for Colorectal Cancer Surveillance in Hodgkin Lymphoma Survivors.

PHF6 promotes non-homologous end joining and G2 checkpoint recovery.

The structural basis for cohesin–CTCF-anchored loops

IBD-Associated Dysplastic Lesions Show More Chromosomal Instability Than Sporadic Adenomas.

P-glycoprotein (ABCB1/MDR1) limits brain accumulation and Cytochrome P450-3A (CYP3A) restricts oral availability of the novel FGFR4 inhibitor fisogatinib (BLU-554).

Bioanalysis of EGFRm inhibitor osimertinib, and its glutathione cycle- and desmethyl metabolites by liquid chromatography-tandem mass spectrometry.

Embryonal and Alveolar Rhabdomyosarcoma in Adults: Real-Life Data From a Tertiary Sarcoma Centre.

Sequence-dependent trafficking and activity of GDE2, a GPI-specific phospholipase promoting neuronal differentiation.

ENERGIZE: a Phase III study of neoadjuvant chemotherapy alone or with nivolumab with/without linrodostat mesylate for muscle-invasive bladder cancer.

Elevated baseline serum PD-1 or PD-L1 predicts poor outcome of PD-1 inhibition therapy in metastatic melanoma.

Bioanalytical LC-MS/MS validation of therapeutic drug monitoring assays in oncology.

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes.

Prostate-Specific Membrane Antigen-Guided Surgery.

The "Psychosocial Aspects in Hereditary Cancer" questionnaire in women attending breast cancer genetic clinics: Psychometric validation across French-, German- and Spanish-language versions.

Lidocaine as treatment for neonatal seizures: Evaluation of previously developed population pharmacokinetic models and dosing regimen.

Tumor organoid-T-cell coculture systems.

A roadmap for the next decade in cancer research.

Cognitive behavioral therapy or graded exercise therapy compared with usual care for severe fatigue in patients with advanced cancer during treatment: a randomized controlled trial.

Diffusion-weighted MRI with ADC mapping for response prediction and assessment of oesophageal cancer: A systematic review.

Internet-based cognitive behavioral therapy aimed at alleviating treatment-induced menopausal symptoms in breast cancer survivors: Moderators and mediators of treatment effects.

Multicenter randomized controlled trial to evaluate the efficacy and tolerability of frozen gloves for the prevention of chemotherapy-induced peripheral neuropathy.

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Local and regional treatment response by ¹⁸FDG-PET-CT-scans 4 weeks after concurrent hypofractionated chemoradiotherapy in locally advanced NSCLC.