Publications

Cancer research communications

Combined Inhibition of EZH2 and FGFR is Synergistic in BAP1-deficient Malignant Mesothelioma.

03-01-2024

International journal of radiation oncology, biology, physics

Disease-Free Survival of Patients With Muscle-Invasive Bladder Cancer Treated With Radical Cystectomy Versus Bladder-Preserving Therapy: A Nationwide Study.

01-01-2024

Nature medicine

Author Correction: High- or low-dose preoperative ipilimumab plus nivolumab in stage III urothelial cancer: the phase 1B NABUCCO trial.

01-01-2024

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

International Validation of the Immunoscore Biopsy in Patients With Rectal Cancer Managed by a Watch-and-Wait Strategy.

01-01-2024

International journal of radiation oncology, biology, physics

Risk Modeling for Individualization of the FLAME Focal Boost Approach in External Beam Radiation Therapy for Patients With Localized Prostate Cancer.

01-01-2024

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Clinical research for global needs of radiation oncology.

01-01-2024

Clinical and translational science

Predictability of human exposure by human-CYP3A4-transgenic mouse models: A meta-analysis.

01-01-2024

FEBS open bio

Acquired and intrinsic resistance to vemurafenib in BRAF^V600E -driven melanoma brain metastases.

01-01-2024

Seminars in radiation oncology

Quantitative MRI on MR-Linacs: Towards Biological Image-Guided Adaptive Radiotherapy.

01-01-2024

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Development and validation of an LC-MS/MS method for the quantification of KRAS^G12C inhibitor opnurasib in several mouse matrices and its application in a pharmacokinetic mouse study.

01-01-2024

Cell research

LICOB: a powerful organoid platform for drug discovery.

01-01-2024

PharmacoEconomics - open

Early Cost-Effectiveness Analysis of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Gastric Cancer Patients with Limited Peritoneal Carcinomatosis.

01-01-2024

Nature genetics

A chromatin-regulated biphasic circuit coordinates IL-1β-mediated inflammation.

01-01-2024

International journal of computer assisted radiology and surgery

Ultrasound guidance in navigated liver surgery: toward deep-learning enhanced compensation of deformation and organ motion.

01-01-2024

ESMO open

Long-term second primary cancer risk in adolescent and young adult (15-39 years) cancer survivors: a population-based study in the Netherlands between 1989 and 2018.

01-01-2024

Nature reviews. Urology

Turning up the heat: CTLA4 blockade in urothelial cancer.

01-01-2024

Nature reviews. Molecular cell biology

Challenges and opportunities in macromolecular structure determination.

01-01-2024

Annals of behavioral medicine : a publication of the Society of Behavioral Medicine

Using the Behavior Change Wheel to Identify and Understand Key Facilitators and Barriers for Lifestyle Care for Postmenopausal Breast Cancer Survivors: A Delphi-Study.

01-01-2024

Diseases of the colon and rectum

Prognostic Implications of Lateral Lymph Nodes in Rectal Cancer: A Population-Based Cross-sectional Study With Standardized Radiological Evaluation After Dedicated Training.

01-01-2024

Clinical and translational radiation oncology

Phase I feasibility study of Olaparib in combination with loco-regional radiotherapy in head and neck squamous cell carcinoma.

01-01-2024

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association

Effect of preoperative chemotherapy on the histopathological classification of gastric cancer.

01-01-2024

European journal of cancer (Oxford, England : 1990)

The features and management of acquired resistance to PD1-based therapy in metastatic melanoma.

01-01-2024

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

"Primer shot" fractionation with an early treatment break is theoretically superior to consecutive weekday fractionation schemes for early-stage non-small cell lung cancer.

01-01-2024

BJOG : an international journal of obstetrics and gynaecology

Urinary incontinence more than 15 years after premenopausal risk-reducing salpingo-oophorectomy: a multicentre cross-sectional study.

01-01-2024

Journal of medical imaging (Bellingham, Wash.)

Deep learning-based breast region segmentation in raw and processed digital mammograms: generalization across views and vendors.

01-01-2024

Physics and imaging in radiation oncology

Response letter to Wahid et al. regarding our publication "A network score-based metric to optimize the quality assurance of automatic radiotherapy target segmentations".

01-01-2024

Seminars in radiation oncology

Intrafraction Motion Management With MR-Guided Radiation Therapy.

01-01-2024

Pigment cell & melanoma research

Seasonal variation of anti-PD-1 outcome in melanoma-Results from a Dutch patient cohort.

01-01-2024

Molecular oncology

Proteomics on malignant pleural effusions reveals ERα loss in metastatic breast cancer associates with SGK1-NDRG1 deregulation.

01-01-2024

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

A common germline variant in CYP11B1 is associated with adverse clinical outcome of treatment with abiraterone or enzalutamide.

31-12-2023

Journal of clinical medicine

Same Journey, Different Paths: Caregiver Burden among Informal Caregivers of Adolescent and Young Adult Patients with an Uncertain or Poor Cancer Prognosis (UPCP).

27-12-2023

Breast disease

Course of objectively measured physical activity and sleep in postmenopausal breast cancer survivors during the COVID-19 pandemic: A 1-year follow-up.

25-12-2023

Insights into imaging

A European Society of Oncologic Imaging (ESOI) survey on the radiological assessment of response to oncologic treatments in clinical practice.

20-12-2023

Digital health

Strengthening the evidence base for mHealth in clinical practice: Conducting research with standalone or interoperable systems - a viewpoint.

18-12-2023

Frontiers in nutrition

Non-therapeutic plasma levels in individuals utilizing curcumin supplements in daily life.

15-12-2023

ACS chemical biology

Discovery of Molecular Glue Degraders via Isogenic Morphological Profiling.

15-12-2023

Science immunology

Early human lung immune cell development and its role in epithelial cell fate.

15-12-2023

Research square

Artificial intelligence-based morphometric signature to identify ductal carcinoma in situ with low risk of progression to invasive breast cancer.

13-12-2023

Immunity

Chi3l1: New kid on the T cell blockade.

12-12-2023

Nederlands tijdschrift voor geneeskunde

[How long are medical oncology patients in The Netherlands willing to travel for their cancer care?].

12-12-2023

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Survival of Patients With Cancer With DPYD Variant Alleles and Dose-Individualized Fluoropyrimidine Therapy-A Matched-Pair Analysis.

10-12-2023

EMBO molecular medicine

Luminal breast cancer identity is determined by loss of glucocorticoid receptor activity.

07-12-2023

Molecular cell

Locus-specific proteome decoding reveals Fpt1 as a chromatin-associated negative regulator of RNA polymerase III assembly.

07-12-2023

Journal of the National Cancer Institute

Quality of life after patient-initiated vs physician-initiated response to symptom monitoring: the SYMPRO-Lung trial.

06-12-2023

Insights into imaging

Clinicopathological and prognostic value of calcification morphology descriptors in ductal carcinoma in situ of the breast: a systematic review and meta-analysis.

05-12-2023

Diagnostics (Basel, Switzerland)

Tumor Segmentation in Colorectal Ultrasound Images Using an Ensemble Transfer Learning Model: Towards Intra-Operative Margin Assessment.

04-12-2023

Cancer epidemiology

Impact of the COVID-19 pandemic on breast cancer incidence and tumor stage in the Netherlands and Norway: A population-based study.

01-12-2023

Clinical and translational science

The use of microtracers in food-effect trials: An alternative study design for toxic drugs with long half-lives exemplified by the case for alectinib.

01-12-2023

The Journal of pathology

Transcriptomics and proteomics reveal distinct biology for lymph node metastases and tumour deposits in colorectal cancer.

01-12-2023

CPT: pharmacometrics & systems pharmacology

Physiologically-based pharmacokinetic model to predict doxorubicin and paclitaxel exposure in infants through breast milk.

01-12-2023

Combined Inhibition of EZH2 and FGFR is Synergistic in BAP1-deficient Malignant Mesothelioma.

Disease-Free Survival of Patients With Muscle-Invasive Bladder Cancer Treated With Radical Cystectomy Versus Bladder-Preserving Therapy: A Nationwide Study.

Author Correction: High- or low-dose preoperative ipilimumab plus nivolumab in stage III urothelial cancer: the phase 1B NABUCCO trial.

International Validation of the Immunoscore Biopsy in Patients With Rectal Cancer Managed by a Watch-and-Wait Strategy.

Risk Modeling for Individualization of the FLAME Focal Boost Approach in External Beam Radiation Therapy for Patients With Localized Prostate Cancer.

Clinical research for global needs of radiation oncology.

Predictability of human exposure by human-CYP3A4-transgenic mouse models: A meta-analysis.

Acquired and intrinsic resistance to vemurafenib in BRAFV600E -driven melanoma brain metastases.

Quantitative MRI on MR-Linacs: Towards Biological Image-Guided Adaptive Radiotherapy.

Development and validation of an LC-MS/MS method for the quantification of KRASG12C inhibitor opnurasib in several mouse matrices and its application in a pharmacokinetic mouse study.

LICOB: a powerful organoid platform for drug discovery.

Early Cost-Effectiveness Analysis of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Gastric Cancer Patients with Limited Peritoneal Carcinomatosis.

A chromatin-regulated biphasic circuit coordinates IL-1β-mediated inflammation.

Ultrasound guidance in navigated liver surgery: toward deep-learning enhanced compensation of deformation and organ motion.

Long-term second primary cancer risk in adolescent and young adult (15-39 years) cancer survivors: a population-based study in the Netherlands between 1989 and 2018.

Turning up the heat: CTLA4 blockade in urothelial cancer.

Challenges and opportunities in macromolecular structure determination.

Using the Behavior Change Wheel to Identify and Understand Key Facilitators and Barriers for Lifestyle Care for Postmenopausal Breast Cancer Survivors: A Delphi-Study.

Prognostic Implications of Lateral Lymph Nodes in Rectal Cancer: A Population-Based Cross-sectional Study With Standardized Radiological Evaluation After Dedicated Training.

Phase I feasibility study of Olaparib in combination with loco-regional radiotherapy in head and neck squamous cell carcinoma.

Effect of preoperative chemotherapy on the histopathological classification of gastric cancer.

The features and management of acquired resistance to PD1-based therapy in metastatic melanoma.

"Primer shot" fractionation with an early treatment break is theoretically superior to consecutive weekday fractionation schemes for early-stage non-small cell lung cancer.

Urinary incontinence more than 15 years after premenopausal risk-reducing salpingo-oophorectomy: a multicentre cross-sectional study.

Deep learning-based breast region segmentation in raw and processed digital mammograms: generalization across views and vendors.

Response letter to Wahid et al. regarding our publication "A network score-based metric to optimize the quality assurance of automatic radiotherapy target segmentations".

Intrafraction Motion Management With MR-Guided Radiation Therapy.

Seasonal variation of anti-PD-1 outcome in melanoma-Results from a Dutch patient cohort.

Proteomics on malignant pleural effusions reveals ERα loss in metastatic breast cancer associates with SGK1-NDRG1 deregulation.

A common germline variant in CYP11B1 is associated with adverse clinical outcome of treatment with abiraterone or enzalutamide.

Same Journey, Different Paths: Caregiver Burden among Informal Caregivers of Adolescent and Young Adult Patients with an Uncertain or Poor Cancer Prognosis (UPCP).

Course of objectively measured physical activity and sleep in postmenopausal breast cancer survivors during the COVID-19 pandemic: A 1-year follow-up.

A European Society of Oncologic Imaging (ESOI) survey on the radiological assessment of response to oncologic treatments in clinical practice.

Strengthening the evidence base for mHealth in clinical practice: Conducting research with standalone or interoperable systems - a viewpoint.

Non-therapeutic plasma levels in individuals utilizing curcumin supplements in daily life.

Discovery of Molecular Glue Degraders via Isogenic Morphological Profiling.

Early human lung immune cell development and its role in epithelial cell fate.

Artificial intelligence-based morphometric signature to identify ductal carcinoma in situ with low risk of progression to invasive breast cancer.

Chi3l1: New kid on the T cell blockade.

[How long are medical oncology patients in The Netherlands willing to travel for their cancer care?].

Survival of Patients With Cancer With DPYD Variant Alleles and Dose-Individualized Fluoropyrimidine Therapy-A Matched-Pair Analysis.

Luminal breast cancer identity is determined by loss of glucocorticoid receptor activity.

Locus-specific proteome decoding reveals Fpt1 as a chromatin-associated negative regulator of RNA polymerase III assembly.

Quality of life after patient-initiated vs physician-initiated response to symptom monitoring: the SYMPRO-Lung trial.

Clinicopathological and prognostic value of calcification morphology descriptors in ductal carcinoma in situ of the breast: a systematic review and meta-analysis.

Tumor Segmentation in Colorectal Ultrasound Images Using an Ensemble Transfer Learning Model: Towards Intra-Operative Margin Assessment.

Impact of the COVID-19 pandemic on breast cancer incidence and tumor stage in the Netherlands and Norway: A population-based study.

The use of microtracers in food-effect trials: An alternative study design for toxic drugs with long half-lives exemplified by the case for alectinib.

Transcriptomics and proteomics reveal distinct biology for lymph node metastases and tumour deposits in colorectal cancer.

Physiologically-based pharmacokinetic model to predict doxorubicin and paclitaxel exposure in infants through breast milk.

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Acquired and intrinsic resistance to vemurafenib in BRAF^V600E -driven melanoma brain metastases.

Development and validation of an LC-MS/MS method for the quantification of KRAS^G12C inhibitor opnurasib in several mouse matrices and its application in a pharmacokinetic mouse study.