Publications

Immunity

Adoptive T cell therapy targeting an inducible and broadly shared product of aberrant mRNA translation.

14-01-2025

Cancer discovery

Conquering Overtreatment of DCIS: Lessons from PRECISION.

13-01-2025

Cancer discovery

Early Detection of Ovarian Cancer Using Cell-Free DNA Fragmentomes and Protein Biomarkers.

13-01-2025

Science advances

NAC regulates metabolism and cell fate in intestinal stem cells.

10-01-2025

Frontiers in immunology

Generation of effective and specific human TCRs against tumor/testis antigen NY-ESO-1 in mice with humanized T cell recognition system.

08-01-2025

Proceedings of the National Academy of Sciences of the United States of America

Deciphering the role of the MALT1-RC3H1 axis in regulating GPX4 protein stability.

07-01-2025

Genes & development

BRCA1 and BRCA2: from cancer susceptibility to synthetic lethality.

07-01-2025

Molecular cell

ZNF143 is a transcriptional regulator of nuclear-encoded mitochondrial genes that acts independently of looping and CTCF.

02-01-2025

The New England journal of medicine

Final, 10-Year Outcomes with Nivolumab plus Ipilimumab in Advanced Melanoma.

02-01-2025

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Development and validation of ultra-performance liquid chromatography tandem mass spectrometry methods for the quantitative analysis of the antiparasitic drug DNDI-6148 in human plasma and various mouse biomatrices.

01-01-2025

ESMO open

The pathway alteration load is a pan-cancer determinant of outcome of targeted therapies: results from the Drug Rediscovery Protocol (DRUP).

01-01-2025

Gastroenterology

Combining Colonoscopy With Fecal Immunochemical Test Can Improve Current Familial Colorectal Cancer Colonoscopy Surveillance: A Modelling Study.

01-01-2025

European journal of cancer (Oxford, England : 1990)

Impact of personalized response-directed surgery and adjuvant therapy on survival after neoadjuvant immunotherapy in stage III melanoma: Comparison of 3-year data from PRADO and OpACIN-neo.

01-01-2025

Gastroenterology

Stool-Based Testing for Post-Polypectomy Colorectal Cancer Surveillance Safely Reduces Colonoscopies: The MOCCAS Study.

01-01-2025

Gynecologic oncology

Less is more: The benefits of reduced follow-up in gynecologic cancers.

01-01-2025

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Protocol compliance in a multicentric phase III trial investigating scheduled adaptive radiotherapy and dose painting in head and neck cancer.

01-01-2025

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Moving beyond barriers: a mixed-method study to develop evidence-based strategies to improve implementation of PROMs in clinical oncology care.

01-01-2025

Endocrine-related cancer

The complex landscape of luminal breast cancer.

01-01-2025

European radiology

Diagnostic performance of ADC and ADCratio in MRI-based prostate cancer assessment: A systematic review and meta-analysis.

01-01-2025

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Development of a prediction model for clinically-relevant fatigue: a multi-cancer approach.

01-01-2025

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

A novel lineage-tracing tool reveals that hypoxic tumor cells drive tumor relapse after radiotherapy.

01-01-2025

Head & neck

The association between skeletal muscle mass and sensorineural hearing loss upon cisplatin-based chemoradiotherapy in patients with head and neck squamous cell carcinoma.

01-01-2025

Journal of vascular and interventional radiology : JVIR

The Influence of Preablation Embolization Particle Size on the Size of the Microwave Ablation Zone in a Porcine Orthotopic Renal Tumor Model.

01-01-2025

Nature

The oestrous cycle stage affects mammary tumour sensitivity to chemotherapy.

01-01-2025

Key Publication

Alimentary pharmacology & therapeutics

Faecal Volatile Organic Compounds to Detect Colorectal Neoplasia in Lynch Syndrome-A Prospective Longitudinal Multicentre Study.

01-01-2025

JAMA oncology

First-Line Systemic Treatment for Initially Unresectable Colorectal Liver Metastases: Post Hoc Analysis of the CAIRO5 Randomized Clinical Trial.

01-01-2025

Lung cancer (Amsterdam, Netherlands)

Impact of HA-PCI on self-reported cognitive functioning and brain metastases in small-cell lung cancer: Pooled findings of NCT01780675 and PREMER trials.

01-01-2025

Nature medicine

Autogene cevumeran with or without atezolizumab in advanced solid tumors: a phase 1 trial.

01-01-2025

Magnetic resonance imaging

vSHARP: Variable Splitting Half-quadratic ADMM algorithm for reconstruction of inverse-problems.

01-01-2025

Annals of oncology : official journal of the European Society for Medical Oncology

Cutaneous melanoma: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up.

01-01-2025

Genome biology

Molecular dependencies and genomic consequences of a global DNA damage tolerance defect.

31-12-2024

Breast cancer research : BCR

Polygenic score distribution differences across European ancestry populations: implications for breast cancer risk prediction.

29-12-2024

Frontiers in immunology

Clinical-scale, modular manufacturing of tumor-reactive TILs using a closed and automated culture system.

24-12-2024

Proceedings of the National Academy of Sciences of the United States of America

An antibiotic that mediates immune destruction of senescent cancer cells.

24-12-2024

Genome research

Characterization of DNA methylation reader proteins in Arabidopsis thaliana.

23-12-2024

STAR protocols

Protocol for studying macrophage lipid crosstalk with murine tumor cells.

20-12-2024

Molecular cell

STK19 drives transcription-coupled repair by stimulating repair complex stability, RNA Pol II ubiquitylation, and TFIIH recruitment.

19-12-2024

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Metastatic breast cancer patients' preferences for exercise programs: a latent class analysis using data from a survey in five European countries.

18-12-2024

Cell systems

Optimized reporters for multiplexed detection of transcription factor activity.

18-12-2024

Cell systems

A three-node Turing gene circuit forms periodic spatial patterns in bacteria.

18-12-2024

The Journal of infectious diseases

Disease-Specific Differences in Pharmacokinetics of Paromomycin and Miltefosine Between Post-Kala-Azar Dermal Leishmaniasis and Visceral Leishmaniasis Patients in Eastern Africa.

16-12-2024

Pharmaceuticals (Basel, Switzerland)

A Repurposed Drug Selection Pipeline to Identify CNS-Penetrant Drug Candidates for Glioblastoma.

14-12-2024

Science advances

Transcription processes compete with loop extrusion to homogenize promoter and enhancer dynamics.

13-12-2024

Nucleic acids research

Chemotherapeutic agents and leucine deprivation induce codon-biased aberrant protein production in cancer.

11-12-2024

Cancer cell

Targeting the immune privilege of tumor-initiating cells to enhance cancer immunotherapy.

09-12-2024

Signal transduction and targeted therapy

Efficacy and safety of lenvatinib plus gefitinib in lenvatinib-resistant hepatocellular carcinomas: a prospective, single-arm exploratory trial.

09-12-2024

Cancer cell

Molecular heterogeneity in urothelial carcinoma and determinants of clinical benefit to PD-L1 blockade.

09-12-2024

Cancer discovery

TCR-Engineered T Cells Directed against Ropporin-1 Constitute a Safe and Effective Treatment for Triple-Negative Breast Cancer.

02-12-2024

Clinical cancer research : an official journal of the American Association for Cancer Research

Safety, Efficacy, and Biomarker Analysis of Crizotinib in MET-Mutated Non-Small Cell Lung Cancer-Results from the Drug Rediscovery Protocol.

02-12-2024

Bladder cancer (Amsterdam, Netherlands)

Systemic induction therapy in patients with locally advanced or node-positive urothelial carcinoma: Evaluating treatment outcomes.

01-12-2024

Adoptive T cell therapy targeting an inducible and broadly shared product of aberrant mRNA translation.

Conquering Overtreatment of DCIS: Lessons from PRECISION.

Early Detection of Ovarian Cancer Using Cell-Free DNA Fragmentomes and Protein Biomarkers.

NAC regulates metabolism and cell fate in intestinal stem cells.

Generation of effective and specific human TCRs against tumor/testis antigen NY-ESO-1 in mice with humanized T cell recognition system.

Deciphering the role of the MALT1-RC3H1 axis in regulating GPX4 protein stability.

BRCA1 and BRCA2: from cancer susceptibility to synthetic lethality.

ZNF143 is a transcriptional regulator of nuclear-encoded mitochondrial genes that acts independently of looping and CTCF.

Final, 10-Year Outcomes with Nivolumab plus Ipilimumab in Advanced Melanoma.

Development and validation of ultra-performance liquid chromatography tandem mass spectrometry methods for the quantitative analysis of the antiparasitic drug DNDI-6148 in human plasma and various mouse biomatrices.

The pathway alteration load is a pan-cancer determinant of outcome of targeted therapies: results from the Drug Rediscovery Protocol (DRUP).

Combining Colonoscopy With Fecal Immunochemical Test Can Improve Current Familial Colorectal Cancer Colonoscopy Surveillance: A Modelling Study.

Impact of personalized response-directed surgery and adjuvant therapy on survival after neoadjuvant immunotherapy in stage III melanoma: Comparison of 3-year data from PRADO and OpACIN-neo.

Stool-Based Testing for Post-Polypectomy Colorectal Cancer Surveillance Safely Reduces Colonoscopies: The MOCCAS Study.

Less is more: The benefits of reduced follow-up in gynecologic cancers.

Protocol compliance in a multicentric phase III trial investigating scheduled adaptive radiotherapy and dose painting in head and neck cancer.

Moving beyond barriers: a mixed-method study to develop evidence-based strategies to improve implementation of PROMs in clinical oncology care.

The complex landscape of luminal breast cancer.

Diagnostic performance of ADC and ADCratio in MRI-based prostate cancer assessment: A systematic review and meta-analysis.

Development of a prediction model for clinically-relevant fatigue: a multi-cancer approach.

A novel lineage-tracing tool reveals that hypoxic tumor cells drive tumor relapse after radiotherapy.

The association between skeletal muscle mass and sensorineural hearing loss upon cisplatin-based chemoradiotherapy in patients with head and neck squamous cell carcinoma.

The Influence of Preablation Embolization Particle Size on the Size of the Microwave Ablation Zone in a Porcine Orthotopic Renal Tumor Model.

The oestrous cycle stage affects mammary tumour sensitivity to chemotherapy.

Faecal Volatile Organic Compounds to Detect Colorectal Neoplasia in Lynch Syndrome-A Prospective Longitudinal Multicentre Study.

First-Line Systemic Treatment for Initially Unresectable Colorectal Liver Metastases: Post Hoc Analysis of the CAIRO5 Randomized Clinical Trial.

Impact of HA-PCI on self-reported cognitive functioning and brain metastases in small-cell lung cancer: Pooled findings of NCT01780675 and PREMER trials.

Autogene cevumeran with or without atezolizumab in advanced solid tumors: a phase 1 trial.

vSHARP: Variable Splitting Half-quadratic ADMM algorithm for reconstruction of inverse-problems.

Cutaneous melanoma: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up.

Molecular dependencies and genomic consequences of a global DNA damage tolerance defect.

Polygenic score distribution differences across European ancestry populations: implications for breast cancer risk prediction.

Clinical-scale, modular manufacturing of tumor-reactive TILs using a closed and automated culture system.

An antibiotic that mediates immune destruction of senescent cancer cells.

Characterization of DNA methylation reader proteins in Arabidopsis thaliana.

Protocol for studying macrophage lipid crosstalk with murine tumor cells.

STK19 drives transcription-coupled repair by stimulating repair complex stability, RNA Pol II ubiquitylation, and TFIIH recruitment.

Metastatic breast cancer patients' preferences for exercise programs: a latent class analysis using data from a survey in five European countries.

Optimized reporters for multiplexed detection of transcription factor activity.

A three-node Turing gene circuit forms periodic spatial patterns in bacteria.

Disease-Specific Differences in Pharmacokinetics of Paromomycin and Miltefosine Between Post-Kala-Azar Dermal Leishmaniasis and Visceral Leishmaniasis Patients in Eastern Africa.

A Repurposed Drug Selection Pipeline to Identify CNS-Penetrant Drug Candidates for Glioblastoma.

Transcription processes compete with loop extrusion to homogenize promoter and enhancer dynamics.

Chemotherapeutic agents and leucine deprivation induce codon-biased aberrant protein production in cancer.

Targeting the immune privilege of tumor-initiating cells to enhance cancer immunotherapy.

Efficacy and safety of lenvatinib plus gefitinib in lenvatinib-resistant hepatocellular carcinomas: a prospective, single-arm exploratory trial.

Molecular heterogeneity in urothelial carcinoma and determinants of clinical benefit to PD-L1 blockade.

TCR-Engineered T Cells Directed against Ropporin-1 Constitute a Safe and Effective Treatment for Triple-Negative Breast Cancer.

Safety, Efficacy, and Biomarker Analysis of Crizotinib in MET-Mutated Non-Small Cell Lung Cancer-Results from the Drug Rediscovery Protocol.

Systemic induction therapy in patients with locally advanced or node-positive urothelial carcinoma: Evaluating treatment outcomes.

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