Publications

Acta crystallographica. Section D, Biological crystallography

ARP/wARP and molecular replacement: the next generation.

01-01-2008

Blood

Treatment-related risk factors for premature menopause following Hodgkin lymphoma.

01-01-2008

The Journal of cell biology

Apoptosis induction by Bid requires unconventional ubiquitination and degradation of its N-terminal fragment.

31-12-2007

Cell

RNA-binding protein Dnd1 inhibits microRNA access to target mRNA.

28-12-2007

The EMBO journal

Localized H3K36 methylation states define histone H4K16 acetylation during transcriptional elongation in Drosophila.

12-12-2007

PLoS genetics

A RNA interference screen identifies the protein phosphatase 2A subunit PR55gamma as a stress-sensitive inhibitor of c-SRC.

01-12-2007

The Lancet. Oncology

Use of 70-gene signature to predict prognosis of patients with node-negative breast cancer: a prospective community-based feasibility study (RASTER).

01-12-2007

Molecular cancer therapeutics

In vitro transport of gimatecan (7-t-butoxyiminomethylcamptothecin) by breast cancer resistance protein, P-glycoprotein, and multidrug resistance protein 2.

01-12-2007

International journal of radiation oncology, biology, physics

A phase I-II study of postoperative capecitabine-based chemoradiotherapy in gastric cancer.

01-12-2007

Current opinion in structural biology

Protein-protein interactions regulate Ubl conjugation.

01-12-2007

International journal of radiation oncology, biology, physics

Strategy for online correction of rotational organ motion for intensity-modulated radiotherapy of prostate cancer.

01-12-2007

Breast (Edinburgh, Scotland)

Explanatory factors for variation in the use of breast conserving surgery and radiotherapy in the Netherlands, 1990-2001.

01-12-2007

Head & neck

Heterogeneity of gene expression profiles in head and neck cancer.

01-12-2007

International journal of radiation oncology, biology, physics

Gene expression profiling to predict outcome after chemoradiation in head and neck cancer.

01-12-2007

Nature

Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1.

29-11-2007

Clinical pharmacokinetics

Population pharmacokinetics and pharmacodynamics of doxorubicin and cyclophosphamide in breast cancer patients: a study by the EORTC-PAMM-NDDG.

22-11-2007

Rapid communications in mass spectrometry : RCM

Development and validation of an assay for the quantitative determination of cladribine nucleotides in MDCKII cells and culture medium using weak anion-exchange liquid chromatography coupled with tandem mass spectrometry.

17-11-2007

Cell cycle (Georgetown, Tex.)

What makes tumors multidrug resistant?

15-11-2007

Blood

Selecting highly affine and well-expressed TCRs for gene therapy of melanoma.

15-11-2007

Cell cycle (Georgetown, Tex.)

Diverse ways to control p27Kip1 function: miRNAs come into play.

15-11-2007

Biochemical pharmacology

Lipid rafts and metabolic energy differentially determine uptake of anti-cancer alkylphospholipids in lymphoma versus carcinoma cells.

15-11-2007

Proceedings of the National Academy of Sciences of the United States of America

A functional genetic screen identifies retinoic acid signaling as a target of histone deacetylase inhibitors.

06-11-2007

Clinical cancer research : an official journal of the American Association for Cancer Research

Population pharmacokinetics and pharmacodynamics of paclitaxel and carboplatin in ovarian cancer patients: a study by the European organization for research and treatment of cancer-pharmacology and molecular mechanisms group and new drug development group.

01-11-2007

Breast cancer research and treatment

Impact of a programme of mass mammography screening for breast cancer on socio-economic variation in survival: a population-based study.

01-11-2007

Molecular biology of the cell

Dual Role of alpha6beta4 integrin in epidermal tumor growth: tumor-suppressive versus tumor-promoting function.

01-11-2007

British journal of clinical pharmacology

Safety and pharmacology of paclitaxel in patients with impaired liver function: a population pharmacokinetic-pharmacodynamic study.

01-11-2007

The Journal of clinical investigation

Knockout of cytochrome P450 3A yields new mouse models for understanding xenobiotic metabolism.

01-11-2007

The American journal of clinical nutrition

Lycopene supplementation elevates circulating insulin-like growth factor binding protein-1 and -2 concentrations in persons at greater risk of colorectal cancer.

01-11-2007

Biomedical chromatography : BMC

Determination of topotecan in human and mouse plasma and in mouse tissue homogenates by reversed-phase high-performance liquid chromatography.

01-11-2007

Clinical cancer research : an official journal of the American Association for Cancer Research

P-glycoprotein and breast cancer resistance protein: two dominant transporters working together in limiting the brain penetration of topotecan.

01-11-2007

Cell

Retinoblastoma teaches a new lesson.

19-10-2007

Acta oncologica (Stockholm, Sweden)

Cognitive complaints and cognitive impairment following BEP chemotherapy in patients with testicular cancer.

16-10-2007

Breast cancer research : BCR

Gene expression profiling and histopathological characterization of triple-negative/basal-like breast carcinomas.

04-10-2007

Hematology/oncology clinics of North America

Are we improving the long-term burden of Hodgkin's lymphoma patients with modern treatment?

01-10-2007

Cancer cell

A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer.

01-10-2007

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Treatment-specific risks of second malignancies and cardiovascular disease in 5-year survivors of testicular cancer.

01-10-2007

The Lancet. Oncology

Cognitive dysfunction in people with cancer.

01-10-2007

Cancer cell

Bmi1 controls tumor development in an Ink4a/Arf-independent manner in a mouse model for glioma.

01-10-2007

Journal of cell science

Requirements for the localization of nesprin-3 at the nuclear envelope and its interaction with plectin.

01-10-2007

Cancer chemotherapy and pharmacology

Novel paclitaxel formulations for oral application: a phase I pharmacokinetic study in patients with solid tumours.

01-10-2007

European journal of cancer (Oxford, England : 1990)

Survival of elderly rectal cancer patients not improved: analysis of population based data on the impact of TME surgery.

01-10-2007

European journal of cancer (Oxford, England : 1990)

COPD in cancer patients: higher prevalence in the elderly, a different treatment strategy in case of primary tumours above the diaphragm, and a worse overall survival in the elderly patient.

01-10-2007

Cancer research

Do MDM2 SNP309 and TP53 R72P interact in breast cancer susceptibility? A large pooled series from the breast cancer association consortium.

01-10-2007

European journal of cancer (Oxford, England : 1990)

Health-related quality of life and health care utilisation among older long-term cancer survivors: a population-based study.

01-10-2007

Physiol Genomics: Physiological genomics

Toxicity of ligand-dependent Cre recombinases and generation of a conditional Cre deleter mouse allowing mosaic recombination in peripheral tissues

19-09-2007

British journal of cancer

Postoperative chemoradiotherapy in gastric cancer -- a Phase I/II dose-finding study of radiotherapy with dose escalation of cisplatin and capecitabine chemotherapy.

17-09-2007

Molecular biology of the cell

Serine phosphorylation of the integrin beta4 subunit is necessary for epidermal growth factor receptor induced hemidesmosome disruption.

01-09-2007

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Survival after negative sentinel lymph node biopsy in breast cancer at least equivalent to after negative extensive axillary dissection.

01-09-2007

Breast cancer research and treatment

Margin status and the risk of local recurrence after breast-conserving treatment of lobular breast cancer.

01-09-2007

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Quantitative and selective assay of 5-methylindirubine, an inhibitor of cyclin-dependent kinases, in murine plasma using coupled liquid chromatography and electrospray tandem mass spectrometry.

01-09-2007