Publications

Medical physics

Validation of deformable registration in head and neck cancer using analysis of variance.

01-11-2012

Bioanalysis

Quantitative determination of erlotinib and O-desmethyl erlotinib in human EDTA plasma and lung tumor tissue.

01-11-2012

Head & neck

Preoperative imaging and surgical margins in maxillectomy patients.

01-11-2012

European journal of radiology

Reducing the throughput time of the diagnostic track involving CT scanning with computer simulation.

01-11-2012

The Journal of pathology

Developmental stage-specific contribution of LGR5(+) cells to basal and luminal epithelial lineages in the postnatal mammary gland.

01-11-2012

Cell

A missing link in genotype-directed cancer therapy.

26-10-2012

British journal of cancer

Risk and prognostic significance of metachronous contralateral testicular germ cell tumours.

23-10-2012

Physics in medicine and biology

Influence of the number of elongated fiducial markers on the localization accuracy of the prostate.

07-10-2012

The EMBO journal

The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension.

03-10-2012

PloS one

EZN-2208 (PEG-SN38) overcomes ABCG2-mediated topotecan resistance in BRCA1-deficient mouse mammary tumors.

03-10-2012

European journal of haematology

Health-related quality of life and disease-specific complaints among multiple myeloma patients up to 10 yr after diagnosis: results from a population-based study using the PROFILES registry.

01-10-2012

Annals of hematology

Perceived information provision and satisfaction among lymphoma and multiple myeloma survivors--results from a Dutch population-based study.

01-10-2012

Patient education and counseling

Breast cancer genetic counseling after diagnosis but before treatment: a pilot study on treatment consequences and psychological impact.

01-10-2012

International journal of radiation oncology, biology, physics

Acute esophagus toxicity in lung cancer patients after intensity modulated radiation therapy and concurrent chemotherapy.

01-10-2012

The Journal of urology

Carboplatin based induction chemotherapy for nonorgan confined bladder cancer--a reasonable alternative for cisplatin unfit patients?

01-10-2012

International journal of radiation oncology, biology, physics

Evaluation of tumor shape variability in head-and-neck cancer patients over the course of radiation therapy using implanted gold markers.

01-10-2012

Psycho-oncology

Information about chemotherapy-associated cognitive problems contributes to cognitive problems in cancer patients.

01-10-2012

Gynecologic oncology

Health related quality of life and symptoms after pelvic lymphadenectomy or radiotherapy vs. no adjuvant regional treatment in early-stage endometrial carcinoma: a large population-based study.

01-10-2012

Annals of oncology : official journal of the European Society for Medical Oncology

Radiofrequency ablation combined with systemic treatment versus systemic treatment alone in patients with non-resectable colorectal liver metastases: a randomized EORTC Intergroup phase II study (EORTC 40004).

01-10-2012

Clinical cancer research : an official journal of the American Association for Cancer Research

Alternative cleavage and polyadenylation during colorectal cancer development.

01-10-2012

Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy

Understanding resistance to targeted cancer drugs through loss of function genetic screens.

01-10-2012

Bioinformatics (Oxford, England)

A regression model for estimating DNA copy number applied to capture sequencing data.

15-09-2012

Cell

RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling.

14-09-2012

The EMBO journal

An N-terminal acidic region of Sgs1 interacts with Rpa70 and recruits Rad53 kinase to stalled forks.

12-09-2012

Cancer cell

Tumor type-dependent function of the par3 polarity protein in skin tumorigenesis.

11-09-2012

Current biology : CB

Distinct roles of talin and kindlin in regulating integrin α5β1 function and trafficking.

11-09-2012

BMJ (Clinical research ed.)

Exposure to diagnostic radiation and risk of breast cancer among carriers of BRCA1/2 mutations: retrospective cohort study (GENE-RAD-RISK).

06-09-2012

Molecular pharmaceutics

Organic anion-transporting polypeptides 1a/1b control the hepatic uptake of pravastatin in mice.

04-09-2012

Patient education and counseling

Endometrial cancer survivors are unsatisfied with received information about diagnosis, treatment and follow-up: a study from the population-based PROFILES registry.

01-09-2012

Annals of oncology : official journal of the European Society for Medical Oncology

Clinical correlates of 'BRCAness' in triple-negative breast cancer of patients receiving adjuvant chemotherapy.

01-09-2012

Journal of gastroenterology

Excess weight among colorectal cancer survivors: target for intervention.

01-09-2012

The American journal of pathology

Targeting BRAFV600E in an inducible murine model of melanoma.

01-09-2012

Journal of cell science

The emerging role of Polycomb repressors in the response to DNA damage.

01-09-2012

Nature reviews. Clinical oncology

Can predictive biomarkers in breast cancer guide adjuvant endocrine therapy?

01-09-2012

Nature reviews. Cancer

The effects of deregulated DNA damage signalling on cancer chemotherapy response and resistance.

01-09-2012

Journal of cellular and molecular medicine

Identification of F-box only protein 7 as a negative regulator of NF-kappaB signalling.

01-09-2012

Cancer causes & control : CCC

Most colorectal cancer survivors live a large proportion of their remaining life in good health.

01-09-2012

The AAPS journal

Performance of methods for handling missing categorical covariate data in population pharmacokinetic analyses.

01-09-2012

Familial cancer

Familial gastric cancer: guidelines for diagnosis, treatment and periodic surveillance.

01-09-2012

European journal of cancer (Oxford, England : 1990)

Socio-economic implications of cancer survivorship: results from the PROFILES registry.

01-09-2012

Cell

Glucosylated hydroxymethyluracil, DNA base J, prevents transcriptional readthrough in Leishmania.

31-08-2012

Sub-cellular biochemistry

Cdt1 and geminin in DNA replication initiation.

25-08-2012

Oncogene

Targeting the epigenome for treatment of cancer.

23-08-2012

BMC research notes

Scenario drafting to anticipate future developments in technology assessment.

16-08-2012

Journal of the American Chemical Society

Binding of the J-binding protein to DNA containing glucosylated hmU (base J) or 5-hmC: evidence for a rapid conformational change upon DNA binding.

15-08-2012

Cell death & disease

Bcl-2 is a better ABT-737 target than Bcl-xL or Bcl-w and only Noxa overcomes resistance mediated by Mcl-1, Bfl-1, or Bcl-B.

09-08-2012

BMC health services research

Exploring improvements in patient logistics in Dutch hospitals with a survey.

01-08-2012

Cytometry. Part A : the journal of the International Society for Analytical Cytology

Validation of a multiparameter flow cytometry method for the determination of phosphorylated extracellular-signal-regulated kinase and DNA in circulating tumor cells.

01-08-2012

Annals of oncology : official journal of the European Society for Medical Oncology

The Dutch Childhood Oncology Group guideline for follow-up of asymptomatic cardiac dysfunction in childhood cancer survivors.

01-08-2012

Investigational new drugs

Two-stage model-based design of cancer phase I dose escalation trials: evaluation using the phase I program of barasertib (AZD1152).

01-08-2012