Publications

Gene therapy

Antigen design enhances the immunogenicity of Semliki Forest virus-based therapeutic human papillomavirus vaccines.

01-07-2015

Molecular psychiatry

Brain organic cation transporter 2 controls response and vulnerability to stress and GSK3β signaling.

01-07-2015

Breast cancer research and treatment

The proportion of postmenopausal breast cancer cases in the Netherlands attributable to lifestyle-related risk factors.

01-07-2015

European journal of cancer (Oxford, England : 1990)

A phase IIb multicentre study comparing the efficacy of trabectedin to doxorubicin in patients with advanced or metastatic untreated soft tissue sarcoma: the TRUSTS trial.

01-07-2015

British journal of cancer

Final results from the large sunitinib global expanded-access trial in metastatic renal cell carcinoma.

30-06-2015

mBio

Haploid Genetic Screen Reveals a Profound and Direct Dependence on Cholesterol for Hantavirus Membrane Fusion.

30-06-2015

BMC cancer

PIpelle Prospective ENDOmetrial carcinoma (PIPENDO) study, pre-operative recognition of high risk endometrial carcinoma: a multicentre prospective cohort study.

30-06-2015

Frontiers in oncology

Spatial Separation of Plk1 Phosphorylation and Activity.

27-06-2015

Science (New York, N.Y.)

GENE REGULATION. A HUSH for transgene expression.

26-06-2015

Immunotherapy

Targeting the T-cell co-stimulatory CD27/CD70 pathway in cancer immunotherapy: rationale and potential.

23-06-2015

Nature

IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis.

18-06-2015

Cell

Wnt Down, Tumors Wind Up?

18-06-2015

American journal of nuclear medicine and molecular imaging

The next evolution in radioguided surgery: breast cancer related sentinel node localization using a freehandSPECT-mobile gamma camera combination.

13-06-2015

Science (New York, N.Y.)

CELL DIVISION CYCLE. Competition between MPS1 and microtubules at kinetochores regulates spindle checkpoint signaling.

12-06-2015

Cell host & microbe

Salmonella Manipulation of Host Signaling Pathways Provokes Cellular Transformation Associated with Gallbladder Carcinoma.

10-06-2015

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Challenges in the Use of DNA Repair Deficiency As a Biomarker in Breast Cancer.

10-06-2015

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Effect of Low-Intensity Physical Activity and Moderate- to High-Intensity Physical Exercise During Adjuvant Chemotherapy on Physical Fitness, Fatigue, and Chemotherapy Completion Rates: Results of the PACES Randomized Clinical Trial.

10-06-2015

Journal of pharmaceutical and biomedical analysis

Development of an LC-MS/MS assay for the quantitative determination of the intracellular 5-fluorouracil nucleotides responsible for the anticancer effect of 5-fluorouracil.

10-06-2015

Stem cell reports

Identification of the Common Origins of Osteoclasts, Macrophages, and Dendritic Cells in Human Hematopoiesis.

09-06-2015

Cell cycle (Georgetown, Tex.)

Two-way communication between the metabolic and cell cycle machineries: the molecular basis.

04-06-2015

Diabetologia

Impact of cancer on use of glucose-lowering drug treatment in individuals with diabetes: potential mechanisms. Reply to Pouwer F [letter].

01-06-2015

Molecular oncology

Decreased expression of ABAT and STC2 hallmarks ER-positive inflammatory breast cancer and endocrine therapy resistance in advanced disease.

01-06-2015

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Re-distribution of brachytherapy dose using a differential dose prescription adapted to risk of local failure in low-risk prostate cancer patients.

01-06-2015

Brain imaging and behavior

Neurotoxicity in breast cancer survivors ≥10 years post-treatment is dependent on treatment type.

01-06-2015

JAMA oncology

Increased Plasma Levels of Chemoresistance-Inducing Fatty Acid 16:4(n-3) After Consumption of Fish and Fish Oil.

01-06-2015

Veterinary and comparative oncology

Inductively coupled plasma mass-spectrometric determination of platinum in excretion products of client-owned pet dogs.

01-06-2015

Anticancer research

Effective Therapeutic Intervention and Comprehensive Genetic Analysis of mTOR Signaling in PEComa: A Case Report.

01-06-2015

JAMA internal medicine

Cardiovascular disease after Hodgkin lymphoma treatment: 40-year disease risk.

01-06-2015

Seminars in oncology

Toxicity patterns with immunomodulating antibodies and their combinations.

01-06-2015

The Lancet. Oncology

Controversies in defining cancer survivorship.

01-06-2015

Journal of medical genetics

Hereditary diffuse gastric cancer: updated clinical guidelines with an emphasis on germline CDH1 mutation carriers.

01-06-2015

Brain : a journal of neurology

Multiple sclerosis-associated CLEC16A controls HLA class II expression via late endosome biogenesis.

01-06-2015

Acta oncologica (Stockholm, Sweden)

Establishing implantation uncertainties for focal brachytherapy with I-125 seeds for the treatment of localized prostate cancer.

01-06-2015

Nature

REV7 counteracts DNA double-strand break resection and affects PARP inhibition.

28-05-2015

Nature

MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection.

28-05-2015

Trials

Impact of a web-based treatment decision aid for early-stage prostate cancer on shared decision-making and health outcomes: study protocol for a randomized controlled trial.

27-05-2015

mBio

Niemann-pick C1 is essential for ebolavirus replication and pathogenesis in vivo.

26-05-2015

Proceedings of the National Academy of Sciences of the United States of America

N-lactoyl-amino acids are ubiquitous metabolites that originate from CNDP2-mediated reverse proteolysis of lactate and amino acids.

26-05-2015

Nature communications

Dissecting the role of aberrant DNA methylation in human leukaemia.

22-05-2015

Cell

In Vivo imaging reveals extracellular vesicle-mediated phenocopying of metastatic behavior.

21-05-2015

Human molecular genetics

Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2.

15-05-2015

Molecular biology of the cell

Integrin α3β1 regulates kidney collecting duct development via TRAF6-dependent K63-linked polyubiquitination of Akt.

15-05-2015

Sensors (Basel, Switzerland)

MMP-2/9-Specific Activatable Lifetime Imaging Agent.

12-05-2015

Scientific reports

Dot1 histone methyltransferases share a distributive mechanism but have highly diverged catalytic properties.

12-05-2015

The EMBO journal

Thymus-derived regulatory T cells restrain pro-inflammatory Th1 responses by downregulating CD70 on dendritic cells.

12-05-2015

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Molecular profiling is rather likely to be cost effective.

10-05-2015

Lancet (London, England)

Maintenance treatment with capecitabine and bevacizumab in metastatic colorectal cancer (CAIRO3): a phase 3 randomised controlled trial of the Dutch Colorectal Cancer Group.

09-05-2015

Journal of applied clinical medical physics

Portal dosimetry in wedged beams.

08-05-2015

Journal of medical Internet research

Response rates for patient-reported outcomes using web-based versus paper questionnaires: comparison of two invitational methods in older colorectal cancer patients.

07-05-2015

Cell

Prospective derivation of a living organoid biobank of colorectal cancer patients.

07-05-2015