Publications

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Impact of an Automatically Generated Cancer Survivorship Care Plan on Patient-Reported Outcomes in Routine Clinical Practice: Longitudinal Outcomes of a Pragmatic, Cluster Randomized Trial.

Acta crystallographica. Section D, Biological crystallography

The structure of the GemC1 coiled coil and its interaction with the Geminin family of coiled-coil proteins.

European journal of cancer (Oxford, England : 1990)

The influence of prior novel androgen receptor targeted therapy on the efficacy of cabazitaxel in men with metastatic castration-resistant prostate cancer.

EMBO molecular medicine

Androgen receptor profiling predicts prostate cancer outcome.

Nature genetics

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.

Cell cycle (Georgetown, Tex.)

Tumor heterogeneity-induced signaling regulates SCLC metastasis.

29-10-2015

Proceedings of the National Academy of Sciences of the United States of America

Preserved genetic diversity in organoids cultured from biopsies of human colorectal cancer metastases.

27-10-2015

Frontiers in immunology

Exploiting the Immunomodulatory Properties of Chemotherapeutic Drugs to Improve the Success of Cancer Immunotherapy.

27-10-2015

Journal of cell science

Initiation of lamellipodia and ruffles involves cooperation between mDia1 and the Arp2/3 complex.

15-10-2015

International journal of cancer

ABCB1 and ABCG2 restrict the brain penetration of a panel of novel EZH2-Inhibitors.

15-10-2015

Journal of cell science

The molecular architecture of hemidesmosomes, as revealed with super-resolution microscopy.

15-10-2015

Science (New York, N.Y.)

Genomic correlates of response to CTLA-4 blockade in metastatic melanoma.

09-10-2015

Biomarkers in medicine

Prognostic significance of the EGFR pathway in nasopharyngeal carcinoma: a systematic review and meta-analysis.

07-10-2015

Mobile genetic elements

Applications of DNA integrating elements: Facing the bias bully.

07-10-2015

Cell reports

APOBEC3B-Mediated Cytidine Deamination Is Required for Estrogen Receptor Action in Breast Cancer.

06-10-2015

Oncogenesis

MiR expression profiles of paired primary colorectal cancer and metastases by next-generation sequencing.

05-10-2015

Molecular pharmaceutics

P-glycoprotein, CYP3A, and Plasma Carboxylesterase Determine Brain Disposition and Oral Availability of the Novel Taxane Cabazitaxel (Jevtana) in Mice.

05-10-2015

Breast cancer research : BCR

Next generation sequencing of triple negative breast cancer to find predictors for chemotherapy response.

03-10-2015

Journal of proteome research

PhosphoPath: Visualization of Phosphosite-centric Dynamics in Temporal Molecular Networks.

02-10-2015

Nature reviews. Clinical oncology

Cognitive effects of endocrine therapy for breast cancer: keep calm and carry on?

Journal of cancer research and clinical oncology

Epstein-Barr virus-targeted therapy in nasopharyngeal carcinoma.

Annals of oncology : official journal of the European Society for Medical Oncology

Inhibition of the spindle assembly checkpoint kinase TTK enhances the efficacy of docetaxel in a triple-negative breast cancer model.

International journal of urology : official journal of the Japanese Urological Association

Advances in sentinel node dissection in prostate cancer from a technical perspective.

Clinical cancer research : an official journal of the American Association for Cancer Research

Translating Pembrolizumab to Clinical Practice: Speak Immunology and Learn Fast!

Molecular oncology

BRCA1-like signature in triple negative breast cancer: Molecular and clinical characterization reveals subgroups with therapeutic potential.

Investigational new drugs

P-glycoprotein and breast cancer resistance protein restrict the brain penetration of the CDK4/6 inhibitor palbociclib.

Cancer research

Genome-Wide Identification and Characterization of Novel Factors Conferring Resistance to Topoisomerase II Poisons in Cancer.

Scientific reports

The lethal response to Cdk1 inhibition depends on sister chromatid alignment errors generated by KIF4 and isoform 1 of PRC1.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Validation of high-performance liquid chromatography-tandem mass spectrometry assays quantifying omacetaxine mepesuccinate and its 4'‑des-methyl and cephalotaxine metabolites in human plasma and urine.

Bioinformatics (Oxford, England)

xHeinz: an algorithm for mining cross-species network modules under a flexible conservation model.

Gynecologic oncology

Characterization of patient-derived tumor xenograft models of endometrial cancer for preclinical evaluation of targeted therapies.

Cancer immunology, immunotherapy : CII

Sunitinib pretreatment improves tumor-infiltrating lymphocyte expansion by reduction in intratumoral content of myeloid-derived suppressor cells in human renal cell carcinoma.

European journal of nuclear medicine and molecular imaging

Erratum to: First-in-human evaluation of a hybrid modality that allows combined radio- and (near-infrared) fluorescence tracing during surgery.

Molecular cell

High-Affinity Sites Form an Interaction Network to Facilitate Spreading of the MSL Complex across the X Chromosome in Drosophila.

Immunology and cell biology

The importance of co-stimulation in the orchestration of T helper cell differentiation.

European journal of nuclear medicine and molecular imaging

Fluorescent radiocolloids: are hybrid tracers the future for lymphatic mapping?

European journal of nuclear medicine and molecular imaging

First-in-human evaluation of a hybrid modality that allows combined radio- and (near-infrared) fluorescence tracing during surgery.

Cell reports

PTPN11 Is a Central Node in Intrinsic and Acquired Resistance to Targeted Cancer Drugs.

29-09-2015

Oncogene

FOXA1 repression is associated with loss of BRCA1 and increased promoter methylation and chromatin silencing in breast cancer.

24-09-2015

Cell

Genome-wide maps of nuclear lamina interactions in single human cells.

24-09-2015

Oncotarget

MGL ligand expression is correlated to BRAF mutation and associated with poor survival of stage III colon cancer patients.

22-09-2015

Chinese journal of cancer

A multilevel pan-cancer map links gene mutations to cancer hallmarks.

14-09-2015

Implementation science : IS

Study protocol: an evaluation of the effectiveness, experiences and costs of a patient-directed strategy compared with a multi-faceted strategy to implement physical cancer rehabilitation programmes for cancer survivors in a European healthcare system; a controlled before and after study.

07-09-2015

BMC cancer

The value of completion axillary treatment in sentinel node positive breast cancer patients undergoing a mastectomy: a Dutch randomized controlled multicentre trial (BOOG 2013-07).

03-09-2015

Molecular therapy : the journal of the American Society of Gene Therapy

Case Report of a Fatal Serious Adverse Event Upon Administration of T Cells Transduced With a MART-1-specific T-cell Receptor.

Journal of cancer survivorship : research and practice

The impact of diabetes on neuropathic symptoms and receipt of chemotherapy among colorectal cancer patients: results from the PROFILES registry.

JAMA oncology

Let Them Eat Fish--Reply.

Journal of cancer survivorship : research and practice

Health-related quality of life is associated with physical activity levels among colorectal cancer survivors: a longitudinal, 3-year study of the PROFILES registry.

Trends in molecular medicine

Stimulating translational research: several European life science institutions put their heads together.