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Systemic inflammation: Cancer's long-distance reach to maximize metastasis.

Seth B Coffelt ,
Karin E de Visser

Abstract

While major improvements have been made in targeting primary tumor growth, metastasis and combating cancer spread remain an enigma. We recently identified a systemic inflammatory cascade involving IL17-producing γδ T cells and neutrophils that advance breast cancer metastasis. These data provide insights into how immune cells promote cancer spread.

More about this publication

Oncoimmunology

Volume 5
Issue nr. 2
Pages e1075694
Publication date 01-02-2016

Full text links

Publisher website (DOI) 10.1080/2162402X.2015.1075694
Europe PubMed Central 27057449
Pubmed 27057449

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