Publications

International journal of pharmaceutics

P-glycoprotein (MDR1/ABCB1) and Breast Cancer Resistance Protein (BCRP/ABCG2) limit brain accumulation of the FLT3 inhibitor quizartinib in mice.

10-02-2019

Oncoimmunology

A large pooled analysis refines gene expression-based molecular subclasses in cutaneous melanoma.

07-02-2019

Cell

Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma.

07-02-2019

Cell

Widespread and Functional RNA Circularization in Localized Prostate Cancer.

07-02-2019

PloS one

The Apparent Diffusion Coefficient (ADC) is a useful biomarker in predicting metastatic colon cancer using the ADC-value of the primary tumor.

06-02-2019

Oncoimmunology

Batf3⁺ DCs and type I IFN are critical for the efficacy of neoadjuvant cancer immunotherapy.

05-02-2019

Journal of pharmaceutical and biomedical analysis

Development, validation, and clinical application of a high-performance liquid chromatography-tandem mass spectrometry assay for the quantification of total intracellular β-decitabine nucleotides and genomic DNA incorporated β-decitabine and 5-methyl-2'-deoxycytidine.

05-02-2019

Journal of pharmaceutical and biomedical analysis

Enzyme linked immunosorbent assay for the quantification of nivolumab and pembrolizumab in human serum and cerebrospinal fluid.

05-02-2019

Nature communications

CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary.

04-02-2019

Head & neck

HLA class II expression on tumor cells and low numbers of tumor-associated macrophages predict clinical outcome in oropharyngeal cancer.

01-02-2019

Annals of oncology : official journal of the European Society for Medical Oncology

Position of a panel of international lung cancer experts on the approval decision for use of durvalumab in stage III non-small-cell lung cancer (NSCLC) by the Committee for Medicinal Products for Human Use (CHMP).

01-02-2019

Critical reviews in oncology/hematology

Corrigendum to "Imaging predictors of treatment outcomes in rectal cancer: An overview" [Crit. Rev. Oncol./Hematol. 129, (September) (2018), 153-162].

01-02-2019

Nature

Tissue curvature and apicobasal mechanical tension imbalance instruct cancer morphogenesis.

01-02-2019

Cancer letters

Metabolic targeting synergizes with MAPK inhibition and delays drug resistance in melanoma.

01-02-2019

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

The acute and late toxicity results of a randomized phase II dose-escalation trial in non-small cell lung cancer (PET-boost trial).

01-02-2019

Cancer research

Radiosensitivity Is an Acquired Vulnerability of PARPi-Resistant BRCA1-Deficient Tumors.

01-02-2019

Annals of oncology : official journal of the European Society for Medical Oncology

Enhancing antitumor response by combining immune checkpoint inhibitors with chemotherapy in solid tumors.

01-02-2019

World journal of urology

The value of periprostatic fascia thickness and fascia preservation as prognostic factors of erectile function after nerve-sparing robot-assisted radical prostatectomy.

01-02-2019

Annals of surgical oncology

Cross-Sectional Study on MRI Restaging After Chemoradiotherapy and Interval to Surgery in Rectal Cancer: Influence on Short- and Long-Term Outcomes.

01-02-2019

International journal of radiation oncology, biology, physics

Tumor Trailing for Liver SBRT on the MR-Linac.

01-02-2019

ERJ open research

Cell-free DNA in the supernatant of pleural effusion can be used to detect driver and resistance mutations, and can guide tyrosine kinase inhibitor treatment decisions.

01-02-2019

JAMA oncology

Comparison of Immediate vs Deferred Cytoreductive Nephrectomy in Patients With Synchronous Metastatic Renal Cell Carcinoma Receiving Sunitinib: The SURTIME Randomized Clinical Trial.

01-02-2019

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

The role of positive psychological changes in anxiety and depression of patients with ovarian tumors and their partners: an observational study from the population-based PROFILES registry.

01-02-2019

BJU international

Psychosocial impact of undergoing prostate cancer screening for men with BRCA1 or BRCA2 mutations.

01-02-2019

Journal of cancer survivorship : research and practice

Financial toxicity is more than costs of care: the relationship between employment and financial toxicity in long-term cancer survivors.

01-02-2019

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Development and validation of an UPLC-MS/MS method for the therapeutic drug monitoring of oral anti-hormonal drugs in oncology.

01-02-2019

Journal of clinical laboratory analysis

Ultrasensitive prostate-specific antigen level as a predictor of biochemical progression after robot-assisted radical prostatectomy: Towards risk adapted follow-up.

01-02-2019

Head & neck

Ototoxicity in locally advanced head and neck cancer patients treated with induction chemotherapy followed by intermediate or high-dose cisplatin-based chemoradiotherapy.

01-02-2019

Journal of cancer survivorship : research and practice

Factors associated with an adverse work outcome in breast cancer survivors 5-10 years after diagnosis: a cross-sectional study.

01-02-2019

Nature

Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences.

01-02-2019

Fertility and sterility

Uterine function, pregnancy complications, and pregnancy outcomes among female childhood cancer survivors.

01-02-2019

The British journal of oral & maxillofacial surgery

Intraoperative verification of resection margins of maxillary malignancies by cone-beam computed tomography.

01-02-2019

Life science alliance

Optimized ChIP-seq method facilitates transcription factor profiling in human tumors.

01-02-2019

Cancer immunology, immunotherapy : CII

Phase 1 study of everolimus and low-dose oral cyclophosphamide in patients with metastatic renal cell carcinoma.

01-02-2019

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico

Inter-observer variation of hippocampus delineation in hippocampal avoidance prophylactic cranial irradiation.

01-02-2019

Scientific reports

Effective CRISPR/Cas9-mediated correction of a Fanconi anemia defect by error-prone end joining or templated repair.

25-01-2019

Nature communications

Shared heritability and functional enrichment across six solid cancers.

25-01-2019

JCI insight

Frequent clonal relations between metastases and non-index prostate cancer lesions.

24-01-2019

Nature communications

Comparative oncogenomics identifies combinations of driver genes and drug targets in BRCA1-mutated breast cancer.

23-01-2019

Briefings in bioinformatics

Principal component analysis of binary genomics data.

18-01-2019

Nature communications

Kinetic analysis of multistep USP7 mechanism shows critical role for target protein in activity.

16-01-2019

Immunity

The First Shall (Be) Last: Understanding Durable T Cell Responses in Immunotherapy.

15-01-2019

PloS one

Towards an understanding of C9orf82 protein/CAAP1 function.

11-01-2019

Nature communications

BRCA2 deficiency instigates cGAS-mediated inflammatory signaling and confers sensitivity to tumor necrosis factor-alpha-mediated cytotoxicity.

09-01-2019

PloS one

TRPM7 residue S1269 mediates cAMP dependence of Ca2+ influx.

08-01-2019

Journal of the American Heart Association

Risk and Temporal Changes of Heart Failure Among 5-Year Childhood Cancer Survivors: a DCOG-LATER Study.

08-01-2019

Pharmaceutical research

Impact of Older Age on the Exposure of Paclitaxel: a Population Pharmacokinetic Study.

07-01-2019

Annals of work exposures and health

Diet, Physical Activity, and Daylight Exposure Patterns in Night-Shift Workers and Day Workers.

07-01-2019

JCO precision oncology

Rationale and Design of the Targeted Agent and Profiling Utilization Registry (TAPUR) Study.

04-01-2019

American journal of human genetics

Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes.

03-01-2019