Publications

Frontiers in immunology

Repertoire Sequencing of B Cells Elucidates the Role of UNG and Mismatch Repair Proteins in Somatic Hypermutation in Humans.

12-09-2019

Communications biology

Proteomic profiling of extracellular vesicles allows for human breast cancer subtyping.

12-09-2019

Pharmaceutical research

Metabolome Analysis Reveals Dermal Histamine Accumulation in Murine Dermatitis Provoked by Genetic Deletion of P-Glycoprotein and Breast Cancer Resistance Protein.

11-09-2019

BMC cancer

Study protocols of three parallel phase 1 trials combining radical radiotherapy with the PARP inhibitor olaparib.

10-09-2019

Journal of pharmaceutical and biomedical analysis

Development and validation of a liquid chromatography-tandem mass spectrometry assay for nine oral anticancer drugs in human plasma.

10-09-2019

Cell

The ChAHP Complex Counteracts Chromatin Looping at CTCF Sites that Emerged from SINE Expansions in Mouse.

05-09-2019

Journal of pharmaceutical and biomedical analysis

Liquid chromatography-tandem mass spectrometric assay for the quantification of galunisertib in human plasma and the application in a pre-clinical study.

05-09-2019

JAMA network open

Association of a Pathway-Specific Genetic Risk Score With Risk of Radiation-Associated Contralateral Breast Cancer.

04-09-2019

Molecular pharmaceutics

P-glycoprotein Limits Ribociclib Brain Exposure and CYP3A4 Restricts Its Oral Bioavailability.

03-09-2019

Psycho-oncology

Anxiety and depression mediate the association between chemotherapy-induced peripheral neuropathy and fatigue: Results from the population-based PROFILES registry.

01-09-2019

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Usability of an online application for reporting the burden of side effects in cancer patients.

01-09-2019

The Journal of surgical research

Feasibility of Micro-Computed Tomography Imaging for Direct Assessment of Surgical Resection Margins During Breast-Conserving Surgery.

01-09-2019

The Journal of molecular diagnostics : JMD

MammaPrint and BluePrint Molecular Diagnostics Using Targeted RNA Next-Generation Sequencing Technology.

01-09-2019

European journal of clinical pharmacology

Individualized dosing of oral targeted therapies in oncology is crucial in the era of precision medicine.

01-09-2019

Cancer chemotherapy and pharmacology

Cytochrome P450 3A4, 3A5, and 2C8 expression in breast, prostate, lung, endometrial, and ovarian tumors: relevance for resistance to taxanes.

01-09-2019

The Lancet. Oncology

Pembrolizumab versus ipilimumab in advanced melanoma (KEYNOTE-006): post-hoc 5-year results from an open-label, multicentre, randomised, controlled, phase 3 study.

01-09-2019

International journal of cancer

Assessment and management of bone health in women with early breast cancer receiving endocrine treatment in the DATA study.

01-09-2019

Clinical and translational radiation oncology

MRI basics for radiation oncologists.

01-09-2019

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

MRI-guided mid-position liver radiotherapy: Validation of image processing and registration steps.

01-09-2019

European urology focus

Defining the Tumor Microenvironment of Penile Cancer by Means of the Cancer Immunogram.

01-09-2019

Der Radiologe

[Imaging of rectal cancer. German version].

01-09-2019

Immuno-oncology technology

Getting visible with exciting IO tech!

01-09-2019

Oral oncology

Health-related quality of life of patients treated with chemoradiotherapy plus or minus prophylactic antibiotics to reduce the number of pneumonias for locally advanced head and neck cancer, the PANTAP study.

01-09-2019

International journal of radiation oncology, biology, physics

Multiparametric MRI Tumor Probability Model for the Detection of Locally Recurrent Prostate Cancer After Radiation Therapy: Pathologic Validation and Comparison With Manual Tumor Delineations.

01-09-2019

Biomedical optics express

Broadband hyperspectral imaging for breast tumor detection using spectral and spatial information.

01-09-2019

Drug discovery today

Impact of organ-on-a-chip technology on pharmaceutical R&D costs.

01-09-2019

Medical physics

Two-dimensional EPID dosimetry for an MR-linac: Proof of concept.

01-09-2019

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Micro cone beam computed tomography for sensitive assessment of radiation-induced late lung toxicity in preclinical models.

01-09-2019

Acta psychiatrica Scandinavica

Phenotypic factors associated with amisulpride-induced weight gain in first-episode psychosis patients (from the OPTiMiSE cohort).

01-09-2019

Journal of mammary gland biology and neoplasia

GATA3 Truncating Mutations Promote Cistromic Re-Programming In Vitro, but Not Mammary Tumor Formation in Mice.

01-09-2019

Health informatics journal

A global, incremental development method for a web-based prostate cancer treatment decision aid and usability testing in a Dutch clinical setting.

01-09-2019

Journal of biophotonics

Optical coherence tomography to detect acute esophageal radiation-induced damage in mice: A validation study.

01-09-2019

Journal of geriatric oncology

The impact of colorectal surgery on health-related quality of life in older functionally dependent patients with cancer - A longitudinal follow-up study.

01-09-2019

Cancer causes & control : CCC

Clinical characteristics and survival patterns of subsequent sarcoma, breast cancer, and melanoma after childhood cancer in the DCOG-LATER cohort.

01-09-2019

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Evaluating a professional patient navigation intervention in a supportive care setting.

01-09-2019

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Long-term survival after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) for patients with peritoneal metastases of urachal cancer.

01-09-2019

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Development and validation of an LC-MS/MS method with a broad linear dynamic range for the quantification of tivozanib in human and mouse plasma, mouse tissue homogenates, and culture medium.

01-09-2019

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Assessment of Simplified Methods for Quantification of ¹⁸F-FDHT Uptake in Patients with Metastatic Castration-Resistant Prostate Cancer.

01-09-2019

Molecular cancer therapeutics

In Vivo ERK1/2 Reporter Predictively Models Response and Resistance to Combined BRAF and MEK Inhibitors in Melanoma.

01-09-2019

Journal of psychosomatic research

Effects and moderators of exercise on sleep in adults with cancer: Individual patient data and aggregated meta-analyses.

01-09-2019

European journal of cancer (Oxford, England : 1990)

Safety and efficacy of nivolumab in patients with rare melanoma subtypes who progressed on or after ipilimumab treatment: a single-arm, open-label, phase II study (CheckMate 172).

01-09-2019

Scientific reports

Two truncating variants in FANCC and breast cancer risk.

29-08-2019

Nature communications

Rebalancing of actomyosin contractility enables mammary tumor formation upon loss of E-cadherin.

23-08-2019

The Journal of biological chemistry

The domain architecture of the protozoan protein J-DNA-binding protein 1 suggests synergy between base J DNA binding and thymidine hydroxylase activity.

23-08-2019

Nucleic acids research

DNA damage tolerance in stem cells, ageing, mutagenesis, disease and cancer therapy.

22-08-2019

ESMO open

Susceptible loci associated with autoimmune disease as potential biomarkers for checkpoint inhibitor-induced immune-related adverse events.

20-08-2019

ESMO open

Targeting prognostic proinflammatory biomarkers to improve outcome on IO drugs.

20-08-2019

BMC medical informatics and decision making

The impact of an online patient decision aid for women with breast cancer considering immediate breast reconstruction: study protocol of a multicenter randomized controlled trial.

19-08-2019

The international journal of behavioral nutrition and physical activity

Which cancer survivors are at risk for a physically inactive and sedentary lifestyle? Results from pooled accelerometer data of 1447 cancer survivors.

16-08-2019

BMC gastroenterology

Prognostic value of microvessel density in stage II and III colon cancer patients: a retrospective cohort study.

16-08-2019

Repertoire Sequencing of B Cells Elucidates the Role of UNG and Mismatch Repair Proteins in Somatic Hypermutation in Humans.

Proteomic profiling of extracellular vesicles allows for human breast cancer subtyping.

Metabolome Analysis Reveals Dermal Histamine Accumulation in Murine Dermatitis Provoked by Genetic Deletion of P-Glycoprotein and Breast Cancer Resistance Protein.

Study protocols of three parallel phase 1 trials combining radical radiotherapy with the PARP inhibitor olaparib.

Development and validation of a liquid chromatography-tandem mass spectrometry assay for nine oral anticancer drugs in human plasma.

The ChAHP Complex Counteracts Chromatin Looping at CTCF Sites that Emerged from SINE Expansions in Mouse.

Liquid chromatography-tandem mass spectrometric assay for the quantification of galunisertib in human plasma and the application in a pre-clinical study.

Association of a Pathway-Specific Genetic Risk Score With Risk of Radiation-Associated Contralateral Breast Cancer.

P-glycoprotein Limits Ribociclib Brain Exposure and CYP3A4 Restricts Its Oral Bioavailability.

Anxiety and depression mediate the association between chemotherapy-induced peripheral neuropathy and fatigue: Results from the population-based PROFILES registry.

Usability of an online application for reporting the burden of side effects in cancer patients.

Feasibility of Micro-Computed Tomography Imaging for Direct Assessment of Surgical Resection Margins During Breast-Conserving Surgery.

MammaPrint and BluePrint Molecular Diagnostics Using Targeted RNA Next-Generation Sequencing Technology.

Individualized dosing of oral targeted therapies in oncology is crucial in the era of precision medicine.

Cytochrome P450 3A4, 3A5, and 2C8 expression in breast, prostate, lung, endometrial, and ovarian tumors: relevance for resistance to taxanes.

Pembrolizumab versus ipilimumab in advanced melanoma (KEYNOTE-006): post-hoc 5-year results from an open-label, multicentre, randomised, controlled, phase 3 study.

Assessment and management of bone health in women with early breast cancer receiving endocrine treatment in the DATA study.

MRI basics for radiation oncologists.

MRI-guided mid-position liver radiotherapy: Validation of image processing and registration steps.

Defining the Tumor Microenvironment of Penile Cancer by Means of the Cancer Immunogram.

[Imaging of rectal cancer. German version].

Getting visible with exciting IO tech!

Health-related quality of life of patients treated with chemoradiotherapy plus or minus prophylactic antibiotics to reduce the number of pneumonias for locally advanced head and neck cancer, the PANTAP study.

Multiparametric MRI Tumor Probability Model for the Detection of Locally Recurrent Prostate Cancer After Radiation Therapy: Pathologic Validation and Comparison With Manual Tumor Delineations.

Broadband hyperspectral imaging for breast tumor detection using spectral and spatial information.

Impact of organ-on-a-chip technology on pharmaceutical R&D costs.

Two-dimensional EPID dosimetry for an MR-linac: Proof of concept.

Micro cone beam computed tomography for sensitive assessment of radiation-induced late lung toxicity in preclinical models.

Phenotypic factors associated with amisulpride-induced weight gain in first-episode psychosis patients (from the OPTiMiSE cohort).

GATA3 Truncating Mutations Promote Cistromic Re-Programming In Vitro, but Not Mammary Tumor Formation in Mice.

A global, incremental development method for a web-based prostate cancer treatment decision aid and usability testing in a Dutch clinical setting.

Optical coherence tomography to detect acute esophageal radiation-induced damage in mice: A validation study.

The impact of colorectal surgery on health-related quality of life in older functionally dependent patients with cancer - A longitudinal follow-up study.

Clinical characteristics and survival patterns of subsequent sarcoma, breast cancer, and melanoma after childhood cancer in the DCOG-LATER cohort.

Evaluating a professional patient navigation intervention in a supportive care setting.

Long-term survival after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) for patients with peritoneal metastases of urachal cancer.

Development and validation of an LC-MS/MS method with a broad linear dynamic range for the quantification of tivozanib in human and mouse plasma, mouse tissue homogenates, and culture medium.

Assessment of Simplified Methods for Quantification of 18F-FDHT Uptake in Patients with Metastatic Castration-Resistant Prostate Cancer.

In Vivo ERK1/2 Reporter Predictively Models Response and Resistance to Combined BRAF and MEK Inhibitors in Melanoma.

Effects and moderators of exercise on sleep in adults with cancer: Individual patient data and aggregated meta-analyses.

Safety and efficacy of nivolumab in patients with rare melanoma subtypes who progressed on or after ipilimumab treatment: a single-arm, open-label, phase II study (CheckMate 172).

Two truncating variants in FANCC and breast cancer risk.

Rebalancing of actomyosin contractility enables mammary tumor formation upon loss of E-cadherin.

The domain architecture of the protozoan protein J-DNA-binding protein 1 suggests synergy between base J DNA binding and thymidine hydroxylase activity.

DNA damage tolerance in stem cells, ageing, mutagenesis, disease and cancer therapy.

Susceptible loci associated with autoimmune disease as potential biomarkers for checkpoint inhibitor-induced immune-related adverse events.

Targeting prognostic proinflammatory biomarkers to improve outcome on IO drugs.

The impact of an online patient decision aid for women with breast cancer considering immediate breast reconstruction: study protocol of a multicenter randomized controlled trial.

Which cancer survivors are at risk for a physically inactive and sedentary lifestyle? Results from pooled accelerometer data of 1447 cancer survivors.

Prognostic value of microvessel density in stage II and III colon cancer patients: a retrospective cohort study.

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Assessment of Simplified Methods for Quantification of ¹⁸F-FDHT Uptake in Patients with Metastatic Castration-Resistant Prostate Cancer.