Publications

Insights into imaging

Radiomics: a critical step towards integrated healthcare.

01-12-2018

Reproductive sciences (Thousand Oaks, Calif.)

Acute Drug Effects on the Human Placental Tissue: The Development of a Placental Murine Xenograft Model.

01-12-2018

Molecular & cellular proteomics : MCP

Doxorubicin-induced DNA Damage Causes Extensive Ubiquitination of Ribosomal Proteins Associated with a Decrease in Protein Translation.

01-12-2018

Investigational new drugs

Translational PK-PD modeling analysis of MCLA-128, a HER2/HER3 bispecific monoclonal antibody, to predict clinical efficacious exposure and dose.

01-12-2018

Breast (Edinburgh, Scotland)

Therapeutic Drug Monitoring of endoxifen as an alternative for CYP2D6 genotyping in individualizing tamoxifen therapy.

01-12-2018

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Cancer survivors not participating in observational patient-reported outcome studies have a lower survival compared to participants: the population-based PROFILES registry.

01-12-2018

International journal of computer assisted radiology and surgery

Accuracy assessment of wireless transponder tracking in the operating room environment.

01-12-2018

British journal of clinical pharmacology

Food-effect study on uracil and dihydrouracil plasma levels as marker for dihydropyrimidine dehydrogenase activity in human volunteers.

01-12-2018

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Identification and assessment of health-related quality of life issues in patients with sporadic desmoid-type fibromatosis: a literature review and focus group study.

01-12-2018

Leukemia

Risk of subsequent myeloid neoplasms after radiotherapy treatment for a solid cancer among adults in the United States, 2000-2014.

01-12-2018

Journal of pharmaceutical and biomedical analysis

Bioanalytical liquid chromatography-tandem mass spectrometric assay for the quantification of the ALK inhibitors alectinib, brigatinib and lorlatinib in plasma and mouse tissue homogenates.

30-11-2018

Nucleic acids research

Dot1 promotes H2B ubiquitination by a methyltransferase-independent mechanism.

30-11-2018

Genome medicine

A role for the unfolded protein response stress sensor ERN1 in regulating the response to MEK inhibitors in KRAS mutant colon cancers.

27-11-2018

Nature communications

Integrative epigenetic taxonomy of primary prostate cancer.

21-11-2018

Nature biotechnology

T cell receptor fingerprinting enables in-depth characterization of the interactions governing recognition of peptide-MHC complexes.

19-11-2018

Breast cancer research : BCR

Inflammation markers and cognitive performance in breast cancer survivors 20 years after completion of chemotherapy: a cohort study.

15-11-2018

Key

Clinical cancer research : an official journal of the American Association for Cancer Research

MELK Inhibition in Diffuse Intrinsic Pontine Glioma.

15-11-2018

International journal of radiation oncology, biology, physics

Quantitative Imaging for Radiation Oncology.

15-11-2018

International journal of radiation oncology, biology, physics

A Self-Sorting Coronal 4D-MRI Method for Daily Image Guidance of Liver Lesions on an MR-LINAC.

15-11-2018

International journal of cancer

Detection of endogenously circulating mesenchymal stem cells in human cancer patients.

15-11-2018

International journal of radiation oncology, biology, physics

Validating a Predictive Atlas of Tumor Shrinkage for Adaptive Radiotherapy of Locally Advanced Lung Cancer.

15-11-2018

Clinical epidemiology

Comparing causes of death of Hodgkin lymphoma and breast cancer patients between medical records and cause-of-death statistics.

15-11-2018

BMC cancer

International phase IV validation study of an EORTC quality of life questionnaire for testicular cancer patients: the EORTC QLQ-TC26.

12-11-2018

PloS one

Role of variant allele fraction and rare SNP filtering to improve cellular DNA repair endpoint association.

09-11-2018

The New England journal of medicine

Sunitinib Alone or after Nephrectomy in Renal Cancer.

08-11-2018

Science translational medicine

Enhanced detection of circulating tumor DNA by fragment size analysis.

07-11-2018

BMC cancer

(Cost-)effectiveness of an internet-based physical activity support program (with and without physiotherapy counselling) on physical activity levels of breast and prostate cancer survivors: design of the PABLO trial.

06-11-2018

Molecular pharmaceutics

ABCB1 Attenuates the Brain Penetration of the PARP Inhibitor AZD2461.

05-11-2018

Journal of cell science

Mechanisms of integrin αVβ5 clustering in flat clathrin lattices.

05-11-2018

Molecular pharmaceutics

P-Glycoprotein (MDR1/ABCB1) Restricts Brain Penetration of the Bruton's Tyrosine Kinase Inhibitor Ibrutinib, While Cytochrome P450-3A (CYP3A) Limits Its Oral Bioavailability.

05-11-2018

The Journal of cell biology

Mapping 3D genome organization relative to nuclear compartments using TSA-Seq as a cytological ruler.

05-11-2018

Nucleic acids research

A limited number of double-strand DNA breaks is sufficient to delay cell cycle progression.

02-11-2018

Abdominal radiology (New York)

Use of magnetic resonance imaging in rectal cancer patients: Society of Abdominal Radiology (SAR) rectal cancer disease-focused panel (DFP) recommendations 2017.

01-11-2018

European journal of cancer (Oxford, England : 1990)

Cancer Core Europe: A European cancer research alliance realizing a research infrastructure with critical mass and programmatic approach to cure cancer in the 21st century.

01-11-2018

Molecular oncology

FOXA1 levels are decreased in pleural breast cancer metastases after adjuvant endocrine therapy, and this is associated with poor outcome.

01-11-2018

European journal of cancer (Oxford, England : 1990)

PanCareLIFE: The scientific basis for a European project to improve long-term care regarding fertility, ototoxicity and health-related quality of life after cancer occurring among children and adolescents.

01-11-2018

European journal of cancer (Oxford, England : 1990)

Monitoring potentially modifiable lifestyle factors in cancer survivors: A narrative review on currently available methodologies and innovations for large-scale surveillance.

01-11-2018

The Lancet. Oncology

DPYD genotype-guided dose individualisation of fluoropyrimidine therapy in patients with cancer: a prospective safety analysis.

01-11-2018

International journal of radiation oncology, biology, physics

Radiation-Induced Lung Density Changes on CT Scan for NSCLC: No Impact of Dose-Escalation Level or Volume.

01-11-2018

Clinical and translational radiation oncology

Magnetic Resonance-based Response Assessment and Dose Adaptation in Human Papilloma Virus Positive Tumors of the Oropharynx treated with Radiotherapy (MR-ADAPTOR): An R-IDEAL stage 2a-2b/Bayesian phase II trial.

01-11-2018

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Multispectral-Fluorescence Imaging as a Tool to Separate Healthy from Disease-Related Lymphatic Anatomy During Robot-Assisted Laparoscopy.

01-11-2018

Nature

Protocadherin-1 is essential for cell entry by New World hantaviruses.

01-11-2018

Cancer letters

CUEDC1 is a primary target of ERα essential for the growth of breast cancer cells.

01-11-2018

Molecular oncology

European Academy of Cancer Sciences - position paper.

01-11-2018

Nature medicine

Neoadjuvant versus adjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma.

01-11-2018

The Journal of pathology

Consensus molecular subtype classification of colorectal adenomas.

01-11-2018

Annals of oncology : official journal of the European Society for Medical Oncology

Starting the fight in the tumor: expert recommendations for the development of human intratumoral immunotherapy (HIT-IT).

01-11-2018

Endocrine-related cancer

Molecular underpinnings of enzalutamide resistance.

01-11-2018

The Lancet. Haematology

Beyond maximum grade: modernising the assessment and reporting of adverse events in haematological malignancies.

01-11-2018

Journal of the National Cancer Institute

Targeting Exercise Interventions to Patients With Cancer in Need: An Individual Patient Data Meta-Analysis.

01-11-2018