Publications

Science translational medicine

Replication stress response defects are associated with response to immune checkpoint blockade in nonhypermutated cancers.

27-10-2021

Proceedings of the National Academy of Sciences of the United States of America

Differential effects of PD-1 and CTLA-4 blockade on the melanoma-reactive CD8 T cell response.

26-10-2021

Journal of pharmaceutical and biomedical analysis

Quantification of anti-SARS-CoV-2 antibodies in human serum with LC-QTOF-MS.

25-10-2021

JMIR cancer

Exploring Cancer Survivor Needs and Preferences for Communicating Personalized Cancer Statistics From Registry Data: Qualitative Multimethod Study.

25-10-2021

The British journal of surgery

Prevalence of nodal involvement in rectal cancer after chemoradiotherapy.

23-10-2021

Pharmaceutics

ABCB1 and ABCG2 Control Brain Accumulation and Intestinal Disposition of the Novel ROS1/TRK/ALK Inhibitor Repotrectinib, While OATP1A/1B, ABCG2, and CYP3A Limit Its Oral Availability.

21-10-2021

Physics in medicine and biology

Deformation trajectory prediction using a neural network trained on finite element data-application to library of CTVs creation for cervical cancer.

21-10-2021

NPJ breast cancer

IHC-based Ki67 as response biomarker to tamoxifen in breast cancer window trials enrolling premenopausal women.

20-10-2021

Scientific reports

Dynamic FRET-FLIM based screening of signal transduction pathways.

20-10-2021

Frontiers in oncology

MR-Linac Radiotherapy - The Beam Angle Selection Problem.

19-10-2021

The EMBO journal

RASSF1C oncogene elicits amoeboid invasion, cancer stemness, and extracellular vesicle release via a SRC/Rho axis.

18-10-2021

Genome medicine

Targeting CDC7 potentiates ATR-CHK1 signaling inhibition through induction of DNA replication stress in liver cancer.

18-10-2021

International journal of cancer

Toxicity of pemetrexed during renal impairment explained-Implications for safe treatment.

15-10-2021

BMC public health

Supporting participation in paid work of cancer survivors and their partners in the Netherlands: protocol of the SusTained Employability in cancer Patients and their partnerS (STEPS) multi-centre randomized controlled trial and cohort study.

12-10-2021

Journal of chromatography. A

A generic sample preparation method for the multiplex analysis of seven therapeutic monoclonal antibodies in human plasma or serum with liquid chromatography-tandem mass spectrometry.

11-10-2021

Cancers

Hospital Variation in Cancer Treatments and Survival OutComes of Advanced Melanoma Patients: Nationwide Quality Assurance in The Netherlands.

11-10-2021

Journal of clinical medicine

The Prolonged Diagnostic Pathway of Young Adults (Aged 25-39) with Cancer in the United Kingdom: Results from the Young Adult Cancer Patient Journey Study.

11-10-2021

Cancers

Value of Assessing Peripheral Vascularization with Micro-Flow Imaging, Resistive Index and Absent Hilum Sign as Predictor for Malignancy in Lymph Nodes in Head and Neck Squamous Cell Carcinoma.

10-10-2021

Scientific reports

Germline variants and breast cancer survival in patients with distant metastases at primary breast cancer diagnosis.

05-10-2021

JMIR cancer

Characteristics of Participants and Nonparticipants in a Blended Internet-Based Physical Activity Trial for Breast and Prostate Cancer Survivors: Cross-sectional Study.

05-10-2021

Immuno-oncology technology

The (re)discovery of tumor-intrinsic determinants of immune sensitivity by functional genetic screens.

01-10-2021

Medical physics

Automatic breast lesion detection in ultrafast DCE-MRI using deep learning.

01-10-2021

Breast cancer research and treatment

Fatigue and resting-state functional brain networks in breast cancer patients treated with chemotherapy.

01-10-2021

Nature reviews. Gastroenterology & hepatology

Exploring liver cancer biology through functional genetic screens.

01-10-2021

Current opinion in cell biology

Intravital microscopy to illuminate cell state plasticity during metastasis.

01-10-2021

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Diagnostic Value, Oncologic Outcomes, and Safety Profile of Image-Guided Surgery Technologies During Robot-Assisted Lymph Node Dissection with Sentinel Node Biopsy for Prostate Cancer.

01-10-2021

Drug and alcohol dependence

The suitability of oral diacetylmorphine in treatment-refractory patients with heroin dependence: A scoping review.

01-10-2021

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Technologic (R)Evolution Leads to Detection of More Sentinel Nodes in Patients with Melanoma in the Head and Neck Region.

01-10-2021

Seminars in immunology

Impact of cancer cell-intrinsic features on neutrophil behavior.

01-10-2021

Molecular cancer research : MCR

Identification of Autophagy-Related Genes as Targets for Senescence Induction Using a Customizable CRISPR-Based Suicide Switch Screen.

01-10-2021

Human gene therapy

Multimodular Optimization of Chemically Regulated T Cell Switches Demonstrates Flexible and Interchangeable Nature of Immune Cell Signaling Domains.

01-10-2021

Brain and behavior

Psychosocial factors and cancer incidence (PSY-CA): Protocol for individual participant data meta-analyses.

01-10-2021

Molecular oncology

The Porto European Cancer Research Summit 2021.

01-10-2021

The FEBS journal

Conserved residues Glu37 and Trp229 play an essential role in protein folding of β-lactamase.

01-10-2021

Breast cancer research and treatment

Improved risk estimation of locoregional recurrence, secondary contralateral tumors and distant metastases in early breast cancer: the INFLUENCE 2.0 model.

01-10-2021

Cellular and molecular life sciences : CMLS

Signals for antigen-independent differentiation of memory CD8⁺ T cells.

01-10-2021

Clinica chimica acta; international journal of clinical chemistry

Retrospective analysis of serum testosterone levels by LC-MS/MS in chemically castrated prostate cancer patients: Biological variation and analytical performance specifications.

01-10-2021

Pharmacological research

ABCB1 and ABCG2, but not CYP3A4 limit oral availability and brain accumulation of the RET inhibitor pralsetinib.

01-10-2021

Molecular cancer research : MCR

The Prognostic Potential of Human Prostate Cancer-Associated Macrophage Subtypes as Revealed by Single-Cell Transcriptomics.

01-10-2021

The British journal of radiology

Descriptive analysis of MRI functional changes occurring during reduced dose radiotherapy for myxoid liposarcomas.

01-10-2021

Preventive medicine

Impact of the suspension and restart of the Dutch breast cancer screening program on breast cancer incidence and stage during the COVID-19 pandemic.

01-10-2021

PloS one

Proteomic analysis identifies novel binding partners of BAP1.

01-10-2021

ESMO open

Priorities and preferences of advanced soft tissue sarcoma patients starting palliative chemotherapy: baseline results from the HOLISTIC study.

01-10-2021

European journal of cancer (Oxford, England : 1990)

Sex-differences in symptoms and functioning in >5000 cancer survivors: Results from the PROFILES registry.

01-10-2021

British journal of cancer

Mendelian randomisation study of smoking exposure in relation to breast cancer risk.

01-10-2021

Annals of oncology : official journal of the European Society for Medical Oncology

A revolving research fund to study efficient use of expensive drugs: big wheels keep on turning.

01-10-2021

Clinical cancer research : an official journal of the American Association for Cancer Research

Predictive Immune-Checkpoint Blockade Classifiers Identify Tumors Responding to Inhibition of PD-1 and/or CTLA-4.

01-10-2021

Psycho-oncology

Change in cognition before and after non-central nervous system cancer diagnosis: A population-based cohort study.

01-10-2021

The British journal of radiology

A decade of multi-modality PET and MR imaging in abdominal oncology.

01-10-2021

Journal of robotic surgery

Multi-wavelength fluorescence imaging with a da Vinci Firefly-a technical look behind the scenes.

01-10-2021

Replication stress response defects are associated with response to immune checkpoint blockade in nonhypermutated cancers.

Differential effects of PD-1 and CTLA-4 blockade on the melanoma-reactive CD8 T cell response.

Quantification of anti-SARS-CoV-2 antibodies in human serum with LC-QTOF-MS.

Exploring Cancer Survivor Needs and Preferences for Communicating Personalized Cancer Statistics From Registry Data: Qualitative Multimethod Study.

Prevalence of nodal involvement in rectal cancer after chemoradiotherapy.

ABCB1 and ABCG2 Control Brain Accumulation and Intestinal Disposition of the Novel ROS1/TRK/ALK Inhibitor Repotrectinib, While OATP1A/1B, ABCG2, and CYP3A Limit Its Oral Availability.

Deformation trajectory prediction using a neural network trained on finite element data-application to library of CTVs creation for cervical cancer.

IHC-based Ki67 as response biomarker to tamoxifen in breast cancer window trials enrolling premenopausal women.

Dynamic FRET-FLIM based screening of signal transduction pathways.

MR-Linac Radiotherapy - The Beam Angle Selection Problem.

RASSF1C oncogene elicits amoeboid invasion, cancer stemness, and extracellular vesicle release via a SRC/Rho axis.

Targeting CDC7 potentiates ATR-CHK1 signaling inhibition through induction of DNA replication stress in liver cancer.

Toxicity of pemetrexed during renal impairment explained-Implications for safe treatment.

Supporting participation in paid work of cancer survivors and their partners in the Netherlands: protocol of the SusTained Employability in cancer Patients and their partnerS (STEPS) multi-centre randomized controlled trial and cohort study.

A generic sample preparation method for the multiplex analysis of seven therapeutic monoclonal antibodies in human plasma or serum with liquid chromatography-tandem mass spectrometry.

Hospital Variation in Cancer Treatments and Survival OutComes of Advanced Melanoma Patients: Nationwide Quality Assurance in The Netherlands.

The Prolonged Diagnostic Pathway of Young Adults (Aged 25-39) with Cancer in the United Kingdom: Results from the Young Adult Cancer Patient Journey Study.

Value of Assessing Peripheral Vascularization with Micro-Flow Imaging, Resistive Index and Absent Hilum Sign as Predictor for Malignancy in Lymph Nodes in Head and Neck Squamous Cell Carcinoma.

Germline variants and breast cancer survival in patients with distant metastases at primary breast cancer diagnosis.

Characteristics of Participants and Nonparticipants in a Blended Internet-Based Physical Activity Trial for Breast and Prostate Cancer Survivors: Cross-sectional Study.

The (re)discovery of tumor-intrinsic determinants of immune sensitivity by functional genetic screens.

Automatic breast lesion detection in ultrafast DCE-MRI using deep learning.

Fatigue and resting-state functional brain networks in breast cancer patients treated with chemotherapy.

Exploring liver cancer biology through functional genetic screens.

Intravital microscopy to illuminate cell state plasticity during metastasis.

Diagnostic Value, Oncologic Outcomes, and Safety Profile of Image-Guided Surgery Technologies During Robot-Assisted Lymph Node Dissection with Sentinel Node Biopsy for Prostate Cancer.

The suitability of oral diacetylmorphine in treatment-refractory patients with heroin dependence: A scoping review.

Technologic (R)Evolution Leads to Detection of More Sentinel Nodes in Patients with Melanoma in the Head and Neck Region.

Impact of cancer cell-intrinsic features on neutrophil behavior.

Identification of Autophagy-Related Genes as Targets for Senescence Induction Using a Customizable CRISPR-Based Suicide Switch Screen.

Multimodular Optimization of Chemically Regulated T Cell Switches Demonstrates Flexible and Interchangeable Nature of Immune Cell Signaling Domains.

Psychosocial factors and cancer incidence (PSY-CA): Protocol for individual participant data meta-analyses.

The Porto European Cancer Research Summit 2021.

Conserved residues Glu37 and Trp229 play an essential role in protein folding of β-lactamase.

Improved risk estimation of locoregional recurrence, secondary contralateral tumors and distant metastases in early breast cancer: the INFLUENCE 2.0 model.

Signals for antigen-independent differentiation of memory CD8+ T cells.

Retrospective analysis of serum testosterone levels by LC-MS/MS in chemically castrated prostate cancer patients: Biological variation and analytical performance specifications.

ABCB1 and ABCG2, but not CYP3A4 limit oral availability and brain accumulation of the RET inhibitor pralsetinib.

The Prognostic Potential of Human Prostate Cancer-Associated Macrophage Subtypes as Revealed by Single-Cell Transcriptomics.

Descriptive analysis of MRI functional changes occurring during reduced dose radiotherapy for myxoid liposarcomas.

Impact of the suspension and restart of the Dutch breast cancer screening program on breast cancer incidence and stage during the COVID-19 pandemic.

Proteomic analysis identifies novel binding partners of BAP1.

Priorities and preferences of advanced soft tissue sarcoma patients starting palliative chemotherapy: baseline results from the HOLISTIC study.

Sex-differences in symptoms and functioning in >5000 cancer survivors: Results from the PROFILES registry.

Mendelian randomisation study of smoking exposure in relation to breast cancer risk.

A revolving research fund to study efficient use of expensive drugs: big wheels keep on turning.

Predictive Immune-Checkpoint Blockade Classifiers Identify Tumors Responding to Inhibition of PD-1 and/or CTLA-4.

Change in cognition before and after non-central nervous system cancer diagnosis: A population-based cohort study.

A decade of multi-modality PET and MR imaging in abdominal oncology.

Multi-wavelength fluorescence imaging with a da Vinci Firefly-a technical look behind the scenes.

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Signals for antigen-independent differentiation of memory CD8⁺ T cells.