Publications

European urology focus

Partial Response and Stable Disease Correlate with Positive Outcomes in Atezolizumab-treated Patients with Advanced Urinary Tract Carcinoma.

01-09-2021

Genes, chromosomes & cancer

Genomic and transcriptomic characterization of desmoplastic small round cell tumors.

01-09-2021

Annals of oncology : official journal of the European Society for Medical Oncology

Reply to: 'Real-world prevalence across 159 872 patients with cancer supports the clinical utility of TMB-H to define metastatic solid tumors for treatment with pembrolizumab.' by D. Fabrizio et al.

01-09-2021

Breast cancer research and treatment

Combining method of detection and 70-gene signature for enhanced prognostication of breast cancer.

01-09-2021

European journal of cancer (Oxford, England : 1990)

Breast cancer diagnosed in the post-weaning period is indicative for a poor outcome.

01-09-2021

European journal of cancer (Oxford, England : 1990)

Efficacy thresholds for clinical trials with advanced or metastatic leiomyosarcoma patients: A European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group meta-analysis based on a literature review for soft-tissue sarcomas.

01-09-2021

Palliative medicine

Bereaved relatives' quality of life before and during the COVID-19 pandemic: Results of the prospective, multicenter, observational eQuiPe study.

01-09-2021

Genetics in medicine : official journal of the American College of Medical Genetics

The predictive ability of the 313 variant-based polygenic risk score for contralateral breast cancer risk prediction in women of European ancestry with a heterozygous BRCA1 or BRCA2 pathogenic variant.

01-09-2021

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Optical Navigation of the Drop-In γ-Probe as a Means to Strengthen the Connection Between Robot-Assisted and Radioguided Surgery.

01-09-2021

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Anorectal dose-effect relations for late gastrointestinal toxicity following external beam radiotherapy for prostate cancer in the FLAME trial.

01-09-2021

Abdominal radiology (New York)

CT for lymph node staging of Colon cancer: not only size but also location and number of lymph node count.

01-09-2021

JACC. CardioOncology

Coronary Artery Disease in Young Women After Radiation Therapy for Breast Cancer: The WECARE Study.

01-09-2021

Key Publication

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Planning target volume margin assessment for online adaptive MR-guided dose-escalation in rectal cancer on a 1.5 T MR-Linac.

01-09-2021

European journal of cancer (Oxford, England : 1990)

Stage-specific trends in incidence and survival of cutaneous melanoma in the Netherlands (2003-2018): A nationwide population-based study.

01-09-2021

Annals of internal medicine

Clinical Validation of a Multitarget Fecal Immunochemical Test for Colorectal Cancer Screening : A Diagnostic Test Accuracy Study.

01-09-2021

Applied Sciences

Feasibility of Ex Vivo Margin Assessment with Hyperspectral Imaging during Breast-Conserving Surgery: From Imaging Tissue Slices to Imaging Lumpectomy Specimen

31-08-2021

International journal of molecular sciences

Enhancer of Zeste Homolog 2 (EZH2) Contributes to Rod Photoreceptor Death Process in Several Forms of Retinal Degeneration and Its Activity Can Serve as a Biomarker for Therapy Efficacy.

28-08-2021

Cancers

Radium-223 Treatment of Patients with Metastatic Castration Resistant Prostate Cancer: Biomarkers for Stratification and Response Evaluation.

27-08-2021

Cell reports

Organoid-based drug screening reveals neddylation as therapeutic target for malignant rhabdoid tumors.

24-08-2021

Cancers

Deterioration of Intended Target Volume Radiation Dose Due to Anatomical Changes in Patients with Head-and-Neck Cancer.

24-08-2021

Nature communications

Detection and characterization of lung cancer using cell-free DNA fragmentomes.

20-08-2021

Breast cancer research : BCR

Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment.

18-08-2021

Oncotarget

Diverse transcriptional regulation and functional effects revealed by CRISPR/Cas9-directed epigenetic editing.

17-08-2021

EJNMMI research

A physiologically based pharmacokinetic (PBPK) model to describe organ distribution of ⁶⁸Ga-DOTATATE in patients without neuroendocrine tumors.

16-08-2021

Cancer research

CIP2A Interacts with TopBP1 and Drives Basal-Like Breast Cancer Tumorigenesis.

15-08-2021

Cancer

Ultra-rare sarcomas: A consensus paper from the Connective Tissue Oncology Society community of experts on the incidence threshold and the list of entities.

15-08-2021

Cancer cell

Developing and validating model systems for immuno-oncology.

09-08-2021

Cancers

Preferences of Treatment Strategies among Women with Low-Risk DCIS and Oncologists.

06-08-2021

Cell stem cell

Patient-derived organoids model cervical tissue dynamics and viral oncogenesis in cervical cancer.

05-08-2021

Molecular cell

Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency.

05-08-2021

Cold Spring Harbor perspectives in biology

Formation of Tissue-Resident CD8⁺ T-Cell Memory.

02-08-2021

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

Reaction on the Interpretation of the Hippocampus Avoidance Prophylactic Cranial Irradiation Trial in SCLC (NCT01780675).

01-08-2021

European journal of cancer (Oxford, England : 1990)

Integration of quantitative imaging biomarkers in clinical trials for MR-guided radiotherapy: Conceptual guidance for multicentre studies from the MR-Linac Consortium Imaging Biomarker Working Group.

01-08-2021

Cancer discovery

Werner Helicase Is a Synthetic-Lethal Vulnerability in Mismatch Repair-Deficient Colorectal Cancer Refractory to Targeted Therapies, Chemotherapy, and Immunotherapy.

01-08-2021

JAMA surgery

Perioperative Systemic Therapy vs Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy Alone for Resectable Colorectal Peritoneal Metastases: A Phase 2 Randomized Clinical Trial.

01-08-2021

Histopathology

High CD8⁺ tumour-infiltrating lymphocyte density associates with unfavourable prognosis in oesophageal adenocarcinoma following poor response to neoadjuvant chemoradiotherapy.

01-08-2021

Annals of surgery

Neoadjuvant Cytoreductive Treatment With BRAF/MEK Inhibition of Prior Unresectable Regionally Advanced Melanoma to Allow Complete Surgical Resection, REDUCTOR: A Prospective, Single-arm, Open-label Phase II Trial.

01-08-2021

Breast cancer research and treatment

Pathologic response of ductal carcinoma in situ to neoadjuvant systemic treatment in HER2-positive breast cancer.

01-08-2021

Medical decision making : an international journal of the Society for Medical Decision Making

Modeling Diagnostic Strategies to Manage Toxic Adverse Events following Cancer Immunotherapy.

01-08-2021

Annals of oncology : official journal of the European Society for Medical Oncology

'IMpassionate conflicts' in immunotherapy trials for metastatic triple-negative breast cancer.

01-08-2021

Cancer reports (Hoboken, N.J.)

ModraDoc006, an oral docetaxel formulation in combination with ritonavir (ModraDoc006/r), in metastatic castration-resistant prostate cancer patients: A phase Ib study.

01-08-2021

The breast journal

Randomized controlled trial comparing magnetic marker localization (MaMaLoc) with wire-guided localization in the treatment of early-stage breast cancer.

01-08-2021

European radiology

Introducing the Node Reporting and Data System 1.0 (Node-RADS): a concept for standardized assessment of lymph nodes in cancer.

01-08-2021

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

The first-in-human implementation of adaptive 4D cone beam CT for lung cancer radiotherapy: 4DCBCT in less time with less dose.

01-08-2021

The Journal of urology

Safety and Efficacy of Atezolizumab in Understudied Populations with Pretreated Urinary Tract Carcinoma: Subgroup Analyses of the SAUL Study in Real-World Practice.

01-08-2021

Clinical oncology (Royal College of Radiologists (Great Britain))

Beyond Teenage and Young Adult Cancer Care: Care Experiences of Patients Aged 25-39 Years Old in the UK National Health Service.

01-08-2021

Trends in cell biology

REV7: Jack of many trades.

01-08-2021

JNCI cancer spectrum

Colorectal Cancer Care and Patients' Perceptions Before and During COVID-19: Implications for Subsequent SARS-CoV-2 Infection Waves.

01-08-2021

Acta crystallographica. Section D, Structural biology

CCD²: design constructs for protein expression, the easy way.

01-08-2021

Molecular oncology

Playing cancer at its own game: activating mitogenic signaling as a paradoxical intervention.

01-08-2021

Partial Response and Stable Disease Correlate with Positive Outcomes in Atezolizumab-treated Patients with Advanced Urinary Tract Carcinoma.

Genomic and transcriptomic characterization of desmoplastic small round cell tumors.

Reply to: 'Real-world prevalence across 159 872 patients with cancer supports the clinical utility of TMB-H to define metastatic solid tumors for treatment with pembrolizumab.' by D. Fabrizio et al.

Combining method of detection and 70-gene signature for enhanced prognostication of breast cancer.

Breast cancer diagnosed in the post-weaning period is indicative for a poor outcome.

Efficacy thresholds for clinical trials with advanced or metastatic leiomyosarcoma patients: A European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group meta-analysis based on a literature review for soft-tissue sarcomas.

Bereaved relatives' quality of life before and during the COVID-19 pandemic: Results of the prospective, multicenter, observational eQuiPe study.

The predictive ability of the 313 variant-based polygenic risk score for contralateral breast cancer risk prediction in women of European ancestry with a heterozygous BRCA1 or BRCA2 pathogenic variant.

Optical Navigation of the Drop-In γ-Probe as a Means to Strengthen the Connection Between Robot-Assisted and Radioguided Surgery.

Anorectal dose-effect relations for late gastrointestinal toxicity following external beam radiotherapy for prostate cancer in the FLAME trial.

CT for lymph node staging of Colon cancer: not only size but also location and number of lymph node count.

Coronary Artery Disease in Young Women After Radiation Therapy for Breast Cancer: The WECARE Study.

Planning target volume margin assessment for online adaptive MR-guided dose-escalation in rectal cancer on a 1.5 T MR-Linac.

Stage-specific trends in incidence and survival of cutaneous melanoma in the Netherlands (2003-2018): A nationwide population-based study.

Clinical Validation of a Multitarget Fecal Immunochemical Test for Colorectal Cancer Screening : A Diagnostic Test Accuracy Study.

Feasibility of Ex Vivo Margin Assessment with Hyperspectral Imaging during Breast-Conserving Surgery: From Imaging Tissue Slices to Imaging Lumpectomy Specimen

Enhancer of Zeste Homolog 2 (EZH2) Contributes to Rod Photoreceptor Death Process in Several Forms of Retinal Degeneration and Its Activity Can Serve as a Biomarker for Therapy Efficacy.

Radium-223 Treatment of Patients with Metastatic Castration Resistant Prostate Cancer: Biomarkers for Stratification and Response Evaluation.

Organoid-based drug screening reveals neddylation as therapeutic target for malignant rhabdoid tumors.

Deterioration of Intended Target Volume Radiation Dose Due to Anatomical Changes in Patients with Head-and-Neck Cancer.

Detection and characterization of lung cancer using cell-free DNA fragmentomes.

Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment.

Diverse transcriptional regulation and functional effects revealed by CRISPR/Cas9-directed epigenetic editing.

A physiologically based pharmacokinetic (PBPK) model to describe organ distribution of 68Ga-DOTATATE in patients without neuroendocrine tumors.

CIP2A Interacts with TopBP1 and Drives Basal-Like Breast Cancer Tumorigenesis.

Ultra-rare sarcomas: A consensus paper from the Connective Tissue Oncology Society community of experts on the incidence threshold and the list of entities.

Developing and validating model systems for immuno-oncology.

Preferences of Treatment Strategies among Women with Low-Risk DCIS and Oncologists.

Patient-derived organoids model cervical tissue dynamics and viral oncogenesis in cervical cancer.

Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency.

Formation of Tissue-Resident CD8+ T-Cell Memory.

Reaction on the Interpretation of the Hippocampus Avoidance Prophylactic Cranial Irradiation Trial in SCLC (NCT01780675).

Integration of quantitative imaging biomarkers in clinical trials for MR-guided radiotherapy: Conceptual guidance for multicentre studies from the MR-Linac Consortium Imaging Biomarker Working Group.

Werner Helicase Is a Synthetic-Lethal Vulnerability in Mismatch Repair-Deficient Colorectal Cancer Refractory to Targeted Therapies, Chemotherapy, and Immunotherapy.

Perioperative Systemic Therapy vs Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy Alone for Resectable Colorectal Peritoneal Metastases: A Phase 2 Randomized Clinical Trial.

High CD8+ tumour-infiltrating lymphocyte density associates with unfavourable prognosis in oesophageal adenocarcinoma following poor response to neoadjuvant chemoradiotherapy.

Neoadjuvant Cytoreductive Treatment With BRAF/MEK Inhibition of Prior Unresectable Regionally Advanced Melanoma to Allow Complete Surgical Resection, REDUCTOR: A Prospective, Single-arm, Open-label Phase II Trial.

Pathologic response of ductal carcinoma in situ to neoadjuvant systemic treatment in HER2-positive breast cancer.

Modeling Diagnostic Strategies to Manage Toxic Adverse Events following Cancer Immunotherapy.

'IMpassionate conflicts' in immunotherapy trials for metastatic triple-negative breast cancer.

ModraDoc006, an oral docetaxel formulation in combination with ritonavir (ModraDoc006/r), in metastatic castration-resistant prostate cancer patients: A phase Ib study.

Randomized controlled trial comparing magnetic marker localization (MaMaLoc) with wire-guided localization in the treatment of early-stage breast cancer.

Introducing the Node Reporting and Data System 1.0 (Node-RADS): a concept for standardized assessment of lymph nodes in cancer.

The first-in-human implementation of adaptive 4D cone beam CT for lung cancer radiotherapy: 4DCBCT in less time with less dose.

Safety and Efficacy of Atezolizumab in Understudied Populations with Pretreated Urinary Tract Carcinoma: Subgroup Analyses of the SAUL Study in Real-World Practice.

Beyond Teenage and Young Adult Cancer Care: Care Experiences of Patients Aged 25-39 Years Old in the UK National Health Service.

REV7: Jack of many trades.

Colorectal Cancer Care and Patients' Perceptions Before and During COVID-19: Implications for Subsequent SARS-CoV-2 Infection Waves.

CCD2: design constructs for protein expression, the easy way.

Playing cancer at its own game: activating mitogenic signaling as a paradoxical intervention.

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A physiologically based pharmacokinetic (PBPK) model to describe organ distribution of ⁶⁸Ga-DOTATATE in patients without neuroendocrine tumors.

Formation of Tissue-Resident CD8⁺ T-Cell Memory.

High CD8⁺ tumour-infiltrating lymphocyte density associates with unfavourable prognosis in oesophageal adenocarcinoma following poor response to neoadjuvant chemoradiotherapy.

CCD²: design constructs for protein expression, the easy way.