Publications

Clinical pharmacokinetics

Geographical Variability in Paromomycin Pharmacokinetics Does Not Explain Efficacy Differences between Eastern African and Indian Visceral Leishmaniasis Patients.

01-11-2021

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

ESTRO ACROP guidelines for the delineation of lymph nodal areas in upper gastrointestinal malignancies.

01-11-2021

Cancer immunology, immunotherapy : CII

Clinical outcome of patients with metastatic melanoma of unknown primary in the era of novel therapy.

01-11-2021

Clinical pharmacokinetics

Correction to: Influence of Malnutrition on the Pharmacokinetics of Drugs Used in the Treatment of Poverty-Related Diseases: A Systematic Review.

01-11-2021

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

The impact of anatomical changes during photon or proton based radiation treatment on tumor dose in glioblastoma dose escalation trials.

01-11-2021

European journal of cancer (Oxford, England : 1990)

Adjuvant treatment for melanoma in clinical practice - Trial versus reality.

01-11-2021

International journal of radiation oncology, biology, physics

Sites of First Progression in the Randomized PET-Boost Trial for Patients With Locally Advanced NSCLC.

01-11-2021

Nature chemical biology

Single-cell analysis of regions of interest (SCARI) using a photosensitive tag.

01-11-2021

Clinical pharmacology and therapeutics

Response to "Optimized Alectinib Dose Regimen for Treatment of Patients With ALK-Positive NSCLC Based on Robust Pharmacometric Analyses and Clinical Evidence".

01-11-2021

Developmental dynamics : an official publication of the American Association of Anatomists

LGR6 marks nephron progenitor cells.

01-11-2021

Cancer immunology, immunotherapy : CII

Clinically applicable CD34⁺-derived blood dendritic cell subsets exhibit key subset-specific features and potently boost anti-tumor T and NK cell responses.

01-11-2021

European journal of nuclear medicine and molecular imaging

The increasing potential of nuclear medicine imaging for the evaluation and reduction of normal tissue toxicity from radiation treatments.

01-11-2021

Physics in medicine and biology

Probabilistic target definition and planning in patients with prostate cancer.

28-10-2021

Journal of medicinal chemistry

Imaging Autotaxin In Vivo with ¹⁸F-Labeled Positron Emission Tomography Ligands.

28-10-2021

Cancers

Atlas of Lobular Breast Cancer Models: Challenges and Strategic Directions.

27-10-2021

Pharmaceuticals (Basel, Switzerland)

P-Glycoprotein (ABCB1/MDR1) and BCRP (ABCG2) Limit Brain Accumulation and Cytochrome P450-3A (CYP3A) Restricts Oral Exposure of the RET Inhibitor Selpercatinib (RETEVMO).

27-10-2021

Science translational medicine

Replication stress response defects are associated with response to immune checkpoint blockade in nonhypermutated cancers.

27-10-2021

Proceedings of the National Academy of Sciences of the United States of America

Differential effects of PD-1 and CTLA-4 blockade on the melanoma-reactive CD8 T cell response.

26-10-2021

JMIR cancer

Exploring Cancer Survivor Needs and Preferences for Communicating Personalized Cancer Statistics From Registry Data: Qualitative Multimethod Study.

25-10-2021

Journal of pharmaceutical and biomedical analysis

Quantification of anti-SARS-CoV-2 antibodies in human serum with LC-QTOF-MS.

25-10-2021

The British journal of surgery

Prevalence of nodal involvement in rectal cancer after chemoradiotherapy.

23-10-2021

Pharmaceutics

ABCB1 and ABCG2 Control Brain Accumulation and Intestinal Disposition of the Novel ROS1/TRK/ALK Inhibitor Repotrectinib, While OATP1A/1B, ABCG2, and CYP3A Limit Its Oral Availability.

21-10-2021

Physics in medicine and biology

Deformation trajectory prediction using a neural network trained on finite element data-application to library of CTVs creation for cervical cancer.

21-10-2021

Scientific reports

Dynamic FRET-FLIM based screening of signal transduction pathways.

20-10-2021

NPJ breast cancer

IHC-based Ki67 as response biomarker to tamoxifen in breast cancer window trials enrolling premenopausal women.

20-10-2021

Frontiers in oncology

MR-Linac Radiotherapy - The Beam Angle Selection Problem.

19-10-2021

The EMBO journal

RASSF1C oncogene elicits amoeboid invasion, cancer stemness, and extracellular vesicle release via a SRC/Rho axis.

18-10-2021

European journal of cancer (Oxford, England : 1990)

Crossover and rechallenge with pembrolizumab in recurrent patients from the EORTC 1325-MG/Keynote-054 phase III trial, pembrolizumab versus placebo after complete resection of high-risk stage III melanoma.

18-10-2021

Genome medicine

Targeting CDC7 potentiates ATR-CHK1 signaling inhibition through induction of DNA replication stress in liver cancer.

18-10-2021

International journal of cancer

Toxicity of pemetrexed during renal impairment explained-Implications for safe treatment.

15-10-2021

BMC public health

Supporting participation in paid work of cancer survivors and their partners in the Netherlands: protocol of the SusTained Employability in cancer Patients and their partnerS (STEPS) multi-centre randomized controlled trial and cohort study.

12-10-2021

Journal of chromatography. A

A generic sample preparation method for the multiplex analysis of seven therapeutic monoclonal antibodies in human plasma or serum with liquid chromatography-tandem mass spectrometry.

11-10-2021

Cancers

Hospital Variation in Cancer Treatments and Survival OutComes of Advanced Melanoma Patients: Nationwide Quality Assurance in The Netherlands.

11-10-2021

Journal of clinical medicine

The Prolonged Diagnostic Pathway of Young Adults (Aged 25-39) with Cancer in the United Kingdom: Results from the Young Adult Cancer Patient Journey Study.

11-10-2021

Cancers

Value of Assessing Peripheral Vascularization with Micro-Flow Imaging, Resistive Index and Absent Hilum Sign as Predictor for Malignancy in Lymph Nodes in Head and Neck Squamous Cell Carcinoma.

10-10-2021

Scientific reports

Germline variants and breast cancer survival in patients with distant metastases at primary breast cancer diagnosis.

05-10-2021

JMIR cancer

Characteristics of Participants and Nonparticipants in a Blended Internet-Based Physical Activity Trial for Breast and Prostate Cancer Survivors: Cross-sectional Study.

05-10-2021

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Technologic (R)Evolution Leads to Detection of More Sentinel Nodes in Patients with Melanoma in the Head and Neck Region.

01-10-2021

Seminars in immunology

Impact of cancer cell-intrinsic features on neutrophil behavior.

01-10-2021

Molecular cancer research : MCR

Identification of Autophagy-Related Genes as Targets for Senescence Induction Using a Customizable CRISPR-Based Suicide Switch Screen.

01-10-2021

Human gene therapy

Multimodular Optimization of Chemically Regulated T Cell Switches Demonstrates Flexible and Interchangeable Nature of Immune Cell Signaling Domains.

01-10-2021

Brain and behavior

Psychosocial factors and cancer incidence (PSY-CA): Protocol for individual participant data meta-analyses.

01-10-2021

Molecular oncology

The Porto European Cancer Research Summit 2021.

01-10-2021

The FEBS journal

Conserved residues Glu37 and Trp229 play an essential role in protein folding of β-lactamase.

01-10-2021

Breast cancer research and treatment

Improved risk estimation of locoregional recurrence, secondary contralateral tumors and distant metastases in early breast cancer: the INFLUENCE 2.0 model.

01-10-2021

Cellular and molecular life sciences : CMLS

Signals for antigen-independent differentiation of memory CD8⁺ T cells.

01-10-2021

Clinica chimica acta; international journal of clinical chemistry

Retrospective analysis of serum testosterone levels by LC-MS/MS in chemically castrated prostate cancer patients: Biological variation and analytical performance specifications.

01-10-2021

Pharmacological research

ABCB1 and ABCG2, but not CYP3A4 limit oral availability and brain accumulation of the RET inhibitor pralsetinib.

01-10-2021

Molecular cancer research : MCR

The Prognostic Potential of Human Prostate Cancer-Associated Macrophage Subtypes as Revealed by Single-Cell Transcriptomics.

01-10-2021

The British journal of radiology

Descriptive analysis of MRI functional changes occurring during reduced dose radiotherapy for myxoid liposarcomas.

01-10-2021