Publications

Therapeutic drug monitoring

Validation of a therapeutic drug monitoring strategy for thiotepa in a high-dose chemotherapy regimen.

01-12-2001

Clinical pharmacology and therapeutics

Modulation of the cytochrome P450-mediated metabolism of ifosfamide by ketoconazole and rifampin.

01-08-2001

Cancer chemotherapy and pharmacology

Population pharmacokinetics of ifosfamide and its 2- and 3-dechloroethylated and 4-hydroxylated metabolites in resistant small-cell lung cancer patients.

01-07-2001

Journal of chromatography. B, Biomedical sciences and applications

Sensitive gas chromatographic determination of the cyclophosphamide metabolite 2-dechloroethylcyclophosphamide in human plasma.

15-06-2001

Journal of pharmacokinetics and pharmacodynamics

A mechanism-based pharmacokinetic model for the cytochrome P450 drug-drug interaction between cyclophosphamide and thioTEPA and the autoinduction of cyclophosphamide.

01-06-2001

British journal of clinical pharmacology

Population pharmacokinetics of thioTEPA and its active metabolite TEPA in patients undergoing high-dose chemotherapy.

01-01-2001

Therapeutic drug monitoring

Determination of ifosfamide, 2- and 3-dechloroethyifosfamide using gas chromatography with nitrogen-phosphorus or mass spectrometry detection.

01-10-2000

Cancer chemotherapy and pharmacology

Reduction of cyclophosphamide bioactivation by thioTEPA: critical sequence-dependency in high-dose chemotherapy regimens.

06-09-2000

Journal of chromatography. B, Biomedical sciences and applications

Simple and selective determination of the cyclophosphamide metabolite phosphoramide mustard in human plasma using high-performance liquid chromatography.

18-08-2000

Anti-cancer drugs

The clinical pharmacology of alkylating agents in high-dose chemotherapy.

01-08-2000

Clinical pharmacology and therapeutics

Validation of techniques for the prediction of carboplatin exposure: application of Bayesian methods.

01-06-2000

British journal of clinical pharmacology

Evaluation of the autoinduction of ifosfamide metabolism by a population pharmacokinetic approach using NONMEM.

01-06-2000

Cancer journal (Sudbury, Mass.)

High-dose chemotherapy with peripheral blood progenitor cell transplantation in the adjuvant treatment of breast cancer.

01-04-2000

Therapeutic drug monitoring

Sampling technique from central venous catheters proves critical for pharmacokinetic studies.

01-02-1999

Journal of chromatography. B, Biomedical sciences and applications

High-performance liquid chromatographic determination of stabilized 4-hydroxyifosfamide in human plasma and erythrocytes.

25-09-1998

Journal of chromatography. B, Biomedical sciences and applications

Simultaneous determination of N,N',N"-triethylenethiophosphoramide, cyclophosphamide and some of their metabolites in plasma using capillary gas chromatography.

25-09-1998