Publications

Clinical and experimental immunology

Lack of anti-tumour reactivity despite enhanced numbers of circulating natural killer T cells in two patients with metastatic renal cell carcinoma.

01-12-2010

Current topics in microbiology and immunology

DNA vaccines and intradermal vaccination by DNA tattooing.

26-11-2010

Human gene therapy

Microbead-assisted retroviral transduction for clinical application.

01-10-2010

Cancer immunology, immunotherapy : CII

RNA interference targeting programmed death receptor-1 improves immune functions of tumor-specific T cells.

01-08-2010

Current clinical pharmacology

DNA vaccination in oncology: current status, opportunities and perspectives.

01-08-2010

Annals of oncology : official journal of the European Society for Medical Oncology

Two-protein signature of novel serological markers apolipoprotein-A2 and serum amyloid alpha predicts prognosis in patients with metastatic renal cell cancer and improves the currently used prognostic survival models.

01-07-2010

International journal of pharmaceutics

Lipopolysaccharide contamination in intradermal DNA vaccination: toxic impurity or adjuvant?

05-05-2010

Nature medicine

Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy.

01-05-2010

AAPS PharmSciTech

Naked plasmid DNA formulation: effect of different disaccharides on stability after lyophilisation.

01-03-2010

Journal of controlled release : official journal of the Controlled Release Society

DNA tattoo vaccination: effect on plasmid purity and transfection efficiency of different topoisoforms.

15-10-2009

World journal of urology

Neoadjuvant sunitinib for surgically complex advanced renal cell cancer of doubtful resectability: initial experience with downsizing to reconsider cytoreductive surgery.

01-08-2009

Immunotherapy

Immunotherapeutic strategies: the melanoma example.

01-07-2009

Nature methods

Parallel detection of antigen-specific T-cell responses by multidimensional encoding of MHC multimers.

01-07-2009

Current opinion in immunology

Preclinical development of T cell receptor gene therapy.

01-04-2009

Journal of pharmaceutical and biomedical analysis

Development and validation of an anion-exchange LC-UV method for the quantification and purity determination of the DNA plasmid pDERMATT.

20-02-2009

Journal of immunology (Baltimore, Md. : 1950)

Requirements for effective antitumor responses of TCR transduced T cells.

01-10-2008

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

GMP production of pDERMATT for vaccination against melanoma in a phase I clinical trial.

01-10-2008

Anticancer research

Value of serum S-100B for prediction of distant relapse and survival in stage III B/C melanoma.

30-08-2008

Urologia internationalis

Cytokine therapy response as a selection criterion for cytoreductive nephrectomy in metastatic renal clear-cell carcinoma of intermediate prognosis. Results and conclusions from a combined analysis.

01-07-2008

Journal of immunology (Baltimore, Md. : 1950)

Long-term functionality of TCR-transduced T cells in vivo.

15-05-2008

Journal of immunology (Baltimore, Md. : 1950)

An inducible caspase 9 safety switch can halt cell therapy-induced autoimmune disease.

01-05-2008

Clinical cancer research : an official journal of the American Association for Cancer Research

Sunitinib for treatment of advanced renal cell cancer: primary tumor response.

15-04-2008

Cancer research

Skewing the T-cell repertoire by combined DNA vaccination, host conditioning, and adoptive transfer.

01-04-2008

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Brain metastases in patients with renal cell cancer receiving new targeted treatment.

01-01-2008

Blood

Selecting highly affine and well-expressed TCRs for gene therapy of melanoma.

15-11-2007

Journal of immunology (Baltimore, Md. : 1950)

In vivo antigen stability affects DNA vaccine immunogenicity.

15-08-2007

Journal of immunotherapy (Hagerstown, Md. : 1997)

Phase I clinical study with multiple peptide vaccines in combination with tetanus toxoid and GM-CSF in advanced-stage HLA-A*0201-positive melanoma patients.

02-05-2007

Laboratory investigation; a journal of technical methods and pathology

Validation of SELDI-TOF MS serum protein profiles for renal cell carcinoma in new populations.

01-02-2007

BMC biotechnology

Intravital imaging of fluorescent markers and FRET probes by DNA tattooing.

03-01-2007

Blood

Targeting self-antigens through allogeneic TCR gene transfer.

01-08-2006

Journal of immunology (Baltimore, Md. : 1950)

Immunological and antitumor effects of IL-23 as a cancer vaccine adjuvant.

01-05-2006

Cancer immunology, immunotherapy : CII

Melanoma-specific tumor-infiltrating lymphocytes but not circulating melanoma-specific T cells may predict survival in resected advanced-stage melanoma patients.

01-04-2006

Journal of immunological methods

In situ visualization of antigen-specific T cells in cryopreserved human tissues.

20-03-2006

Nature medicine

Design and use of conditional MHC class I ligands.

01-02-2006

Cancer immunology, immunotherapy : CII

Prolonged low dose IL-2 and thalidomide in progressive metastatic renal cell carcinoma with concurrent radiotherapy to bone and/or soft tissue metastasis: a phase II study.

01-09-2005

Nature medicine

A rapid and potent DNA vaccination strategy defined by in vivo monitoring of antigen expression.

01-08-2005

Cancer immunology, immunotherapy : CII

A phase-II study of pegylated interferon alfa-2b for patients with metastatic renal cell carcinoma and removal of the primary tumor.

01-07-2005

European journal of cancer (Oxford, England : 1990)

Normal values of serum S-100B predict prolonged survival for stage IV melanoma patients.

01-02-2005

Clinical cancer research : an official journal of the American Association for Cancer Research

On the role of melanoma-specific CD8+ T-cell immunity in disease progression of advanced-stage melanoma patients.

15-07-2004

Cancer research

Human telomerase reverse transcriptase-transduced human cytotoxic T cells suppress the growth of human melanoma in immunodeficient mice.

15-03-2004

Journal of immunology (Baltimore, Md. : 1950)

Optimizing the efficacy of epitope-directed DNA vaccination.

15-05-2002

Journal of immunology (Baltimore, Md. : 1950)

A redundant role of the CD3 gamma-immunoreceptor tyrosine-based activation motif in mature T cell function.

15-02-2001

Nature medicine

In situ detection of virus- and tumor-specific T-cell immunity.

01-09-2000

European journal of immunology

Tumor size at the time of adoptive transfer determines whether tumor rejection occurs.

01-05-2000

European journal of immunology

Tracing and characterization of the low-avidity self-specific T cell repertoire.

01-05-2000

The Journal of experimental medicine

Selective expansion of cross-reactive CD8(+) memory T cells by viral variants.

01-11-1999

European journal of immunology

Systemic T cell expansion during localized viral infection.

01-04-1999