Publications

FEBS open bio

Optimizing photoactivation of PA-mCherry for optical pooled CRISPR screens.

01-05-2026

Cell reports

SRBD1, a highly conserved gene required for chromosome individualization.

22-04-2025

FEBS letters

Cytosolic-enhanced dark Epac-based FRET sensors allow for intracellular cAMP detection in live cells via FLIM.

01-04-2025

Science advances

FIRRM/C1orf112 mediates resolution of homologous recombination intermediates in response to DNA interstrand crosslinks.

02-06-2023

Nature communications

A doxycycline- and light-inducible Cre recombinase mouse model for optogenetic genome editing.

28-10-2022

STAR protocols

Protocol for live-cell imaging during Tumor Treating Fields treatment with Inovitro Live.

17-06-2022

Methods in molecular biology (Clifton, N.J.)

Time-Domain Fluorescence Lifetime Imaging of cAMP Levels with EPAC-Based FRET Sensors.

15-03-2022

Scientific reports

Dynamic FRET-FLIM based screening of signal transduction pathways.

20-10-2021

Nature communications

Modular actin nano-architecture enables podosome protrusion and mechanosensing.

15-11-2019

World journal of urology

The value of periprostatic fascia thickness and fascia preservation as prognostic factors of erectile function after nerve-sparing robot-assisted radical prostatectomy.

01-02-2019

PloS one

TRPM7 residue S1269 mediates cAMP dependence of Ca2+ influx.

08-01-2019

Glia

Reactive astrocytes in multiple sclerosis impair neuronal outgrowth through TRPM7-mediated chondroitin sulfate proteoglycan production.

01-01-2019

Cytometry. Part A : the journal of the International Society for Analytical Cytology

Spectral imaging of FRET-based sensors reveals sustained cAMP gradients in three spatial dimensions.

01-10-2018

Nature genetics

Enhancer hubs and loop collisions identified from single-allele topologies.

01-08-2018

Biochimica et biophysica acta. Molecular basis of disease

TRPM7 controls mesenchymal features of breast cancer cells by tensional regulation of SOX4.

01-07-2018

Disease models & mechanisms

Schwann cells are activated by ATP released from neurons in an in vitro cellular model of Miller Fisher syndrome.

01-05-2017

Cancer cell

Glycerophosphodiesterase GDE2 Promotes Neuroblastoma Differentiation through Glypican Release and Is a Marker of Clinical Outcome.

10-10-2016

Nature communications

Hypersensitivity to DNA damage in antephase as a safeguard for genome stability.

26-08-2016

Biology open

PFA fixation enables artifact-free super-resolution imaging of the actin cytoskeleton and associated proteins.

15-07-2016

PloS one

Optimizing Imaging Conditions for Demanding Multi-Color Super Resolution Localization Microscopy.

09-07-2016

Nature methods

siFLIM: single-image frequency-domain FLIM provides fast and photon-efficient lifetime data.

01-06-2016

Frontiers in cellular neuroscience

ATP Released by Injured Neurons Activates Schwann Cells.

01-06-2016

Cardiovascular research

Intracellular tortuosity underlies slow cAMP diffusion in adult ventricular myocytes.

01-06-2016

Frontiers in bioscience (Landmark edition)

Invadosomes - shaping actin networks to follow mechanical cues.

01-06-2016

Biochimica et biophysica acta

Beyond ion-conduction: Channel-dependent and -independent roles of TRP channels during development and tissue homeostasis.

01-06-2016

Cell chemical biology

Optotaxis: Caged Lysophosphatidic Acid Enables Optical Control of a Chemotactic Gradient.

19-05-2016

The Journal of biological chemistry

Rapid Remodeling of Invadosomes by Gi-coupled Receptors: DISSECTING THE ROLE OF Rho GTPases.

26-02-2016

Journal of cell science

Initiation of lamellipodia and ruffles involves cooperation between mDia1 and the Arp2/3 complex.

15-10-2015

Journal of cell science

The molecular architecture of hemidesmosomes, as revealed with super-resolution microscopy.

15-10-2015

Cell

Genome-wide maps of nuclear lamina interactions in single human cells.

24-09-2015

PloS one

Co-Orientation: Quantifying Simultaneous Co-Localization and Orientational Alignment of Filaments in Light Microscopy.

15-07-2015

Molecular biology of the cell

The rod domain is not essential for the function of plectin in maintaining tissue integrity.

01-07-2015

Nature

REV7 counteracts DNA double-strand break resection and affects PARP inhibition.

28-05-2015

Sensors (Basel, Switzerland)

MMP-2/9-Specific Activatable Lifetime Imaging Agent.

12-05-2015

PloS one

Fourth-generation epac-based FRET sensors for cAMP feature exceptional brightness, photostability and dynamic range: characterization of dedicated sensors for FLIM, for ratiometry and with high affinity.

16-04-2015

Journal of cell science

CLIC4 regulates cell adhesion and β1 integrin trafficking.

15-12-2014

European journal of cell biology

Function and regulation of the channel-kinase TRPM7 in health and disease.

01-10-2014

Scientific reports

The fidelity of stochastic single-molecule super-resolution reconstructions critically depends upon robust background estimation.

24-01-2014

Cell calcium

TRPM7 triggers Ca2+ sparks and invadosome formation in neuroblastoma cells.

01-12-2013

Biochimica et biophysica acta

cAMP inhibits migration, ruffling and paxillin accumulation in focal adhesions of pancreatic ductal adenocarcinoma cells: effects of PKA and EPAC.

01-12-2013

Current biology : CB

WAPL-mediated removal of cohesin protects against segregation errors and aneuploidy.

21-10-2013

Nature methods

hiFRET: some tailwind for FRET resolves weak protein interactions.

01-10-2013

Methods in molecular biology (Clifton, N.J.)

Detecting cAMP with an EPAC-based FRET sensor in single living cells.

21-09-2013

Molecular biology of the cell

Phosphorylation of threonine 1736 in the C-terminal tail of integrin β4 contributes to hemidesmosome disassembly.

01-04-2012

Chembiochem : a European journal of chemical biology

Peptide-functionalized luminescent iridium complexes for lifetime imaging of CXCR4 expression.

16-08-2011

PloS one

A mTurquoise-based cAMP sensor for both FLIM and ratiometric read-out has improved dynamic range.

29-04-2011

BioEssays : news and reviews in molecular, cellular and developmental biology

G protein-coupled receptors: the inside story.

01-01-2010

Molecular biology of the cell

Spatiotemporal regulation of chloride intracellular channel protein CLIC4 by RhoA.

01-11-2009

Molecular endocrinology (Baltimore, Md.)

Resistance to antiestrogen arzoxifene is mediated by overexpression of cyclin D1.

01-09-2009

Molecular and cellular biology

Direct spatial control of Epac1 by cyclic AMP.

01-05-2009