Publications

Journal of the American Chemical Society

Class I major histocompatibility complexes loaded by a periodate trigger.

02-09-2009

Immunotherapy

Immunotherapeutic strategies: the melanoma example.

01-07-2009

Nature methods

Parallel detection of antigen-specific T-cell responses by multidimensional encoding of MHC multimers.

01-07-2009

Methods in molecular biology (Clifton, N.J.)

High-throughput T-cell epitope discovery through MHC peptide exchange.

21-04-2009

Current opinion in immunology

Preclinical development of T cell receptor gene therapy.

01-04-2009

Current opinion in immunology

Adoptive T cell therapy of cancer.

01-04-2009

Journal of immunology (Baltimore, Md. : 1950)

Requirements for effective antitumor responses of TCR transduced T cells.

01-10-2008

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

GMP production of pDERMATT for vaccination against melanoma in a phase I clinical trial.

01-10-2008

The Journal of experimental medicine

Dissecting T cell lineage relationships by cellular barcoding.

29-09-2008

Journal of immunology (Baltimore, Md. : 1950)

TCR gene therapy of spontaneous prostate carcinoma requires in vivo T cell activation.

15-08-2008

Journal of immunology (Baltimore, Md. : 1950)

Long-term functionality of TCR-transduced T cells in vivo.

15-05-2008

Journal of immunology (Baltimore, Md. : 1950)

An inducible caspase 9 safety switch can halt cell therapy-induced autoimmune disease.

01-05-2008

Cancer research

Skewing the T-cell repertoire by combined DNA vaccination, host conditioning, and adoptive transfer.

01-04-2008

Proceedings of the National Academy of Sciences of the United States of America

Conditional MHC class I ligands and peptide exchange technology for the human MHC gene products HLA-A1, -A3, -A11, and -B7.

11-03-2008

Blood

Selecting highly affine and well-expressed TCRs for gene therapy of melanoma.

15-11-2007

Journal of immunology (Baltimore, Md. : 1950)

In vivo antigen stability affects DNA vaccine immunogenicity.

15-08-2007

Blood

Effective graft depletion of MiHAg T-cell specificities and consequences for graft-versus-host disease.

01-05-2007

Nature protocols

Generation of peptide-MHC class I complexes through UV-mediated ligand exchange.

05-04-2007

BMC biotechnology

Intravital imaging of fluorescent markers and FRET probes by DNA tattooing.

03-01-2007

Blood

Targeting self-antigens through allogeneic TCR gene transfer.

01-08-2006

Journal of immunology (Baltimore, Md. : 1950)

Generation of T cell help through a MHC class I-restricted TCR.

15-07-2006

Nature medicine

Design and use of conditional MHC class I ligands.

01-02-2006

Cellular and molecular life sciences : CMLS

Dissection of cytotoxic and helper T cell responses.

01-12-2005

Current gene therapy

Prospects and limitations of T cell receptor gene therapy.

01-12-2005

Current opinion in immunology

MHC multimer technology: current status and future prospects.

01-08-2005

Nature medicine

A rapid and potent DNA vaccination strategy defined by in vivo monitoring of antigen expression.

01-08-2005

Methods in molecular medicine

Gene transfer of MHC-restricted receptors.

09-12-2004

Clinical cancer research : an official journal of the American Association for Cancer Research

On the role of melanoma-specific CD8+ T-cell immunity in disease progression of advanced-stage melanoma patients.

15-07-2004

Science (New York, N.Y.)

Antigen bias in T cell cross-priming.

28-05-2004

Cancer research

Human telomerase reverse transcriptase-transduced human cytotoxic T cells suppress the growth of human melanoma in immunodeficient mice.

15-03-2004

Journal of immunology (Baltimore, Md. : 1950)

The impact of self-tolerance on the polyclonal CD8+ T cell repertoire.

15-02-2004

Journal of immunotherapy (Hagerstown, Md. : 1997)

CD8+ T cell tolerance and cancer immunotherapy.

07-01-2003

Journal of immunology (Baltimore, Md. : 1950)

Differential kinetics of antigen-specific CD4+ and CD8+ T cell responses in the regression of retrovirus-induced sarcomas.

15-09-2002

Nature reviews. Immunology

T-cell-receptor gene therapy.

01-07-2002

Proceedings of the National Academy of Sciences of the United States of America

Specificity and affinity motifs for Grb2 SH2-ligand interactions.

25-06-2002

Journal of immunology (Baltimore, Md. : 1950)

Optimizing the efficacy of epitope-directed DNA vaccination.

15-05-2002

Trends in immunology

Adoptive transfer of T-cell immunity.

01-05-2002

Biologicals : journal of the International Association of Biological Standardization

Circumventing T-cell tolerance to tumour antigens.

20-02-2002

Journal of immunology (Baltimore, Md. : 1950)

Can the low-avidity self-specific T cell repertoire be exploited for tumor rejection?

15-01-2002

Nature immunology

Immunotherapy through TCR gene transfer.

01-10-2001

Journal of immunology (Baltimore, Md. : 1950)

Low-avidity self-specific T cells display a pronounced expansion defect that can be overcome by altered peptide ligands.

01-10-2001

Journal of immunology (Baltimore, Md. : 1950)

Redundancy of direct priming and cross-priming in tumor-specific CD8+ T cell responses.

01-10-2001

Blood

Differentiation of cytomegalovirus-specific CD8(+) T cells in healthy and immunosuppressed virus carriers.

01-08-2001

Proceedings of the National Academy of Sciences of the United States of America

Changing T cell specificity by retroviral T cell receptor display.

19-12-2000

Nature immunology

CD27 is required for generation and long-term maintenance of T cell immunity.

01-11-2000

Nature medicine

In situ detection of virus- and tumor-specific T-cell immunity.

01-09-2000

European journal of immunology

Tracing and characterization of the low-avidity self-specific T cell repertoire.

01-05-2000

The Journal of experimental medicine

Selective expansion of cross-reactive CD8(+) memory T cells by viral variants.

01-11-1999

Cellular immunology

Enrichment of an antigen-specific T cell response by retrovirally transduced human dendritic cells.

10-07-1999

European journal of immunology

Systemic T cell expansion during localized viral infection.

01-04-1999

Class I major histocompatibility complexes loaded by a periodate trigger.

Immunotherapeutic strategies: the melanoma example.

Parallel detection of antigen-specific T-cell responses by multidimensional encoding of MHC multimers.

High-throughput T-cell epitope discovery through MHC peptide exchange.

Preclinical development of T cell receptor gene therapy.

Adoptive T cell therapy of cancer.

Requirements for effective antitumor responses of TCR transduced T cells.

GMP production of pDERMATT for vaccination against melanoma in a phase I clinical trial.

Dissecting T cell lineage relationships by cellular barcoding.

TCR gene therapy of spontaneous prostate carcinoma requires in vivo T cell activation.

Long-term functionality of TCR-transduced T cells in vivo.

An inducible caspase 9 safety switch can halt cell therapy-induced autoimmune disease.

Skewing the T-cell repertoire by combined DNA vaccination, host conditioning, and adoptive transfer.

Conditional MHC class I ligands and peptide exchange technology for the human MHC gene products HLA-A1, -A3, -A11, and -B7.

Selecting highly affine and well-expressed TCRs for gene therapy of melanoma.

In vivo antigen stability affects DNA vaccine immunogenicity.

Effective graft depletion of MiHAg T-cell specificities and consequences for graft-versus-host disease.

Generation of peptide-MHC class I complexes through UV-mediated ligand exchange.

Intravital imaging of fluorescent markers and FRET probes by DNA tattooing.

Targeting self-antigens through allogeneic TCR gene transfer.

Generation of T cell help through a MHC class I-restricted TCR.

Design and use of conditional MHC class I ligands.

Dissection of cytotoxic and helper T cell responses.

Prospects and limitations of T cell receptor gene therapy.

MHC multimer technology: current status and future prospects.

A rapid and potent DNA vaccination strategy defined by in vivo monitoring of antigen expression.

Gene transfer of MHC-restricted receptors.

On the role of melanoma-specific CD8+ T-cell immunity in disease progression of advanced-stage melanoma patients.

Antigen bias in T cell cross-priming.

Human telomerase reverse transcriptase-transduced human cytotoxic T cells suppress the growth of human melanoma in immunodeficient mice.

The impact of self-tolerance on the polyclonal CD8+ T cell repertoire.

CD8+ T cell tolerance and cancer immunotherapy.

Differential kinetics of antigen-specific CD4+ and CD8+ T cell responses in the regression of retrovirus-induced sarcomas.

T-cell-receptor gene therapy.

Specificity and affinity motifs for Grb2 SH2-ligand interactions.

Optimizing the efficacy of epitope-directed DNA vaccination.

Adoptive transfer of T-cell immunity.

Circumventing T-cell tolerance to tumour antigens.

Can the low-avidity self-specific T cell repertoire be exploited for tumor rejection?

Immunotherapy through TCR gene transfer.

Low-avidity self-specific T cells display a pronounced expansion defect that can be overcome by altered peptide ligands.

Redundancy of direct priming and cross-priming in tumor-specific CD8+ T cell responses.

Differentiation of cytomegalovirus-specific CD8(+) T cells in healthy and immunosuppressed virus carriers.

Changing T cell specificity by retroviral T cell receptor display.

CD27 is required for generation and long-term maintenance of T cell immunity.

In situ detection of virus- and tumor-specific T-cell immunity.

Tracing and characterization of the low-avidity self-specific T cell repertoire.

Selective expansion of cross-reactive CD8(+) memory T cells by viral variants.

Enrichment of an antigen-specific T cell response by retrovirally transduced human dendritic cells.

Systemic T cell expansion during localized viral infection.

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