Publications

Cancer chemotherapy and pharmacology

Metabolite profiling of the novel anti-cancer agent, plitidepsin, in urine and faeces in cancer patients after administration of ¹⁴C-plitidepsin.

01-09-2018

European journal of cancer (Oxford, England : 1990)

Breast cancer-related deaths according to grade in ductal carcinoma in situ: A Dutch population-based study on patients diagnosed between 1999 and 2012.

01-09-2018

The Journal of pathology

BRCA1-associated mammary tumorigenesis is dependent on estrogen rather than progesterone signaling.

01-09-2018

European journal of cancer (Oxford, England : 1990)

Outcomes by line of therapy and programmed death ligand 1 expression in patients with advanced melanoma treated with pembrolizumab or ipilimumab in KEYNOTE-006: A randomised clinical trial.

01-09-2018

The British journal of radiology

The influence of endorectal filling on rectal cancer staging with MRI.

01-09-2018

Acta oncologica (Stockholm, Sweden)

Patient characteristics and treatment considerations in pancreatic cancer: a population based study in the Netherlands.

01-09-2018

Bioinformatics (Oxford, England)

iTOP: inferring the topology of omics data.

01-09-2018

The Journal of clinical investigation

Neuropilin-1 upregulation elicits adaptive resistance to oncogene-targeted therapies.

31-08-2018

EJNMMI research

Dosimetry methods and clinical applications in peptide receptor radionuclide therapy for neuroendocrine tumours: a literature review.

29-08-2018

Cell reports

Nuclear Receptor Nur77 Limits the Macrophage Inflammatory Response through Transcriptional Reprogramming of Mitochondrial Metabolism.

21-08-2018

BMC Bioinformatics

Rscreenorm: normalization of CRISPR and siRNA screen data for more reproducible hit selection

20-08-2018

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Risk of Solid Cancer After Treatment of Testicular Germ Cell Cancer in the Platinum Era.

20-08-2018

BMC bioinformatics

Rscreenorm: normalization of CRISPR and siRNA screen data for more reproducible hit selection.

20-08-2018

Genome biology

Functional CRISPR screen identifies AP1-associated enhancer regulating FOXF1 to modulate oncogene-induced senescence.

17-08-2018

JCO precision oncology

Evaluation of the HER/PI3K/AKT Family Signaling Network as a Predictive Biomarker of Pathologic Complete Response for Patients With Breast Cancer Treated With Neratinib in the I-SPY 2 TRIAL.

16-08-2018

Clinical cancer research : an official journal of the American Association for Cancer Research

Integrative Kinome Profiling Identifies mTORC1/2 Inhibition as Treatment Strategy in Ovarian Clear Cell Carcinoma.

15-08-2018

International journal of cancer

Etiology of hormone receptor positive breast cancer differs by levels of histologic grade and proliferation.

15-08-2018

International journal of cancer

A clinicopathological study and prognostic factor analysis of 177 salivary duct carcinoma patients from The Netherlands.

15-08-2018

Cancer cell

The Tandem Duplicator Phenotype Is a Prevalent Genome-Wide Cancer Configuration Driven by Distinct Gene Mutations.

13-08-2018

PloS one

Combination of a six microRNA expression profile with four clinicopathological factors for response prediction of systemic treatment in patients with advanced colorectal cancer.

04-08-2018

Journal of cell science

Viral escape from endosomes and host detection at a glance.

03-08-2018

HPB : the official journal of the International Hepato Pancreato Biliary Association

Myosteatosis predicts survival after surgery for periampullary cancer: a novel method using MRI.

01-08-2018

Journal of structural biology

Baculovirus-driven protein expression in insect cells: A benchmarking study.

01-08-2018

Scandinavian journal of gastroenterology

The risk of developing a mismatch repair deficient colorectal cancer after undergoing cholecystectomy.

01-08-2018

The Journal of antimicrobial chemotherapy

Simultaneous population pharmacokinetic modelling of plasma and intracellular PBMC miltefosine concentrations in New World cutaneous leishmaniasis and exploration of exposure-response relationships.

01-08-2018

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

A systematic review of the measurement properties of the European Organisation for Research and Treatment of Cancer In-patient Satisfaction with Care Questionnaire, the EORTC IN-PATSAT32.

01-08-2018

Human reproduction (Oxford, England)

Long-term effects of childhood cancer treatment on hormonal and ultrasound markers of ovarian reserve.

01-08-2018

Nature

The shieldin complex mediates 53BP1-dependent DNA repair.

01-08-2018

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Contouring of prostate tumors on multiparametric MRI: Evaluation of clinical delineations in a multicenter radiotherapy trial.

01-08-2018

The EMBO journal

Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles.

01-08-2018

Journal of clinical pharmacy and therapeutics

Dosing oxaliplatin in a haemodialysis patient with metastatic rectum cancer monitored by free platinum concentrations.

01-08-2018

Oncogene

ARID1A mutation sensitizes most ovarian clear cell carcinomas to BET inhibitors.

01-08-2018

British journal of cancer

Cardiovascular disease incidence after internal mammary chain irradiation and anthracycline-based chemotherapy for breast cancer.

01-08-2018

Journal of thoracic disease

The developing role of FDG PET imaging for prognostication and radiotherapy target volume delineation in non-small cell lung cancer.

01-08-2018

Clinical cancer research : an official journal of the American Association for Cancer Research

Clinicopathological Risk Factors for an Invasive Breast Cancer Recurrence after Ductal Carcinoma In Situ-A Nested Case-Control Study.

01-08-2018

Key Publication

The Journal of pathology

αE-catenin is a candidate tumor suppressor for the development of E-cadherin-expressing lobular-type breast cancer.

01-08-2018

Nature genetics

Enhancer hubs and loop collisions identified from single-allele topologies.

01-08-2018

Open biology

Mouse models in the era of large human tumour sequencing studies.

01-08-2018

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Measuring health-related quality of life in patients with advanced cancer: a systematic review of self-administered measurement instruments.

01-08-2018

Melanoma research

Vemurafenib in BRAF-mutant metastatic melanoma patients in real-world clinical practice: prognostic factors associated with clinical outcomes.

01-08-2018

Cancer research

Integrative Modeling Identifies Key Determinants of Inhibitor Sensitivity in Breast Cancer Cell Lines.

01-08-2018

Annals of oncology : official journal of the European Society for Medical Oncology

Pathological assessment of resection specimens after neoadjuvant therapy for metastatic melanoma.

01-08-2018

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Clinical lymph node staging in colorectal cancer; a flip of the coin?

01-08-2018

Molecular oncology

Loss of androgen receptor signaling in prostate cancer-associated fibroblasts (CAFs) promotes CCL2- and CXCL8-mediated cancer cell migration.

01-08-2018

Clinical breast cancer

Tumor Resection Margin Definitions in Breast-Conserving Surgery: Systematic Review and Meta-analysis of the Current Literature.

01-08-2018

Psycho-oncology

Association between information provision and supportive care needs among ovarian cancer survivors: A cross-sectional study from the PROFILES registry.

01-08-2018

Frontiers of medicine

Taking advantage of drug resistance, a new approach in the war on cancer.

01-08-2018

Nature cell biology

Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells.

01-08-2018

Journal of sex & marital therapy

Sexual Functioning and Relationship Satisfaction of Partners of Breast Cancer Survivors Who Receive Internet-Based Sex Therapy.

25-07-2018

BMC cancer

Mitotic count can predict tamoxifen benefit in postmenopausal breast cancer patients while Ki67 score cannot.

24-07-2018

Metabolite profiling of the novel anti-cancer agent, plitidepsin, in urine and faeces in cancer patients after administration of 14C-plitidepsin.

Breast cancer-related deaths according to grade in ductal carcinoma in situ: A Dutch population-based study on patients diagnosed between 1999 and 2012.

BRCA1-associated mammary tumorigenesis is dependent on estrogen rather than progesterone signaling.

Outcomes by line of therapy and programmed death ligand 1 expression in patients with advanced melanoma treated with pembrolizumab or ipilimumab in KEYNOTE-006: A randomised clinical trial.

The influence of endorectal filling on rectal cancer staging with MRI.

Patient characteristics and treatment considerations in pancreatic cancer: a population based study in the Netherlands.

iTOP: inferring the topology of omics data.

Neuropilin-1 upregulation elicits adaptive resistance to oncogene-targeted therapies.

Dosimetry methods and clinical applications in peptide receptor radionuclide therapy for neuroendocrine tumours: a literature review.

Nuclear Receptor Nur77 Limits the Macrophage Inflammatory Response through Transcriptional Reprogramming of Mitochondrial Metabolism.

Rscreenorm: normalization of CRISPR and siRNA screen data for more reproducible hit selection

Risk of Solid Cancer After Treatment of Testicular Germ Cell Cancer in the Platinum Era.

Rscreenorm: normalization of CRISPR and siRNA screen data for more reproducible hit selection.

Functional CRISPR screen identifies AP1-associated enhancer regulating FOXF1 to modulate oncogene-induced senescence.

Evaluation of the HER/PI3K/AKT Family Signaling Network as a Predictive Biomarker of Pathologic Complete Response for Patients With Breast Cancer Treated With Neratinib in the I-SPY 2 TRIAL.

Integrative Kinome Profiling Identifies mTORC1/2 Inhibition as Treatment Strategy in Ovarian Clear Cell Carcinoma.

Etiology of hormone receptor positive breast cancer differs by levels of histologic grade and proliferation.

A clinicopathological study and prognostic factor analysis of 177 salivary duct carcinoma patients from The Netherlands.

The Tandem Duplicator Phenotype Is a Prevalent Genome-Wide Cancer Configuration Driven by Distinct Gene Mutations.

Combination of a six microRNA expression profile with four clinicopathological factors for response prediction of systemic treatment in patients with advanced colorectal cancer.

Viral escape from endosomes and host detection at a glance.

Myosteatosis predicts survival after surgery for periampullary cancer: a novel method using MRI.

Baculovirus-driven protein expression in insect cells: A benchmarking study.

The risk of developing a mismatch repair deficient colorectal cancer after undergoing cholecystectomy.

Simultaneous population pharmacokinetic modelling of plasma and intracellular PBMC miltefosine concentrations in New World cutaneous leishmaniasis and exploration of exposure-response relationships.

A systematic review of the measurement properties of the European Organisation for Research and Treatment of Cancer In-patient Satisfaction with Care Questionnaire, the EORTC IN-PATSAT32.

Long-term effects of childhood cancer treatment on hormonal and ultrasound markers of ovarian reserve.

The shieldin complex mediates 53BP1-dependent DNA repair.

Contouring of prostate tumors on multiparametric MRI: Evaluation of clinical delineations in a multicenter radiotherapy trial.

Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles.

Dosing oxaliplatin in a haemodialysis patient with metastatic rectum cancer monitored by free platinum concentrations.

ARID1A mutation sensitizes most ovarian clear cell carcinomas to BET inhibitors.

Cardiovascular disease incidence after internal mammary chain irradiation and anthracycline-based chemotherapy for breast cancer.

The developing role of FDG PET imaging for prognostication and radiotherapy target volume delineation in non-small cell lung cancer.

Clinicopathological Risk Factors for an Invasive Breast Cancer Recurrence after Ductal Carcinoma In Situ-A Nested Case-Control Study.

αE-catenin is a candidate tumor suppressor for the development of E-cadherin-expressing lobular-type breast cancer.

Enhancer hubs and loop collisions identified from single-allele topologies.

Mouse models in the era of large human tumour sequencing studies.

Measuring health-related quality of life in patients with advanced cancer: a systematic review of self-administered measurement instruments.

Vemurafenib in BRAF-mutant metastatic melanoma patients in real-world clinical practice: prognostic factors associated with clinical outcomes.

Integrative Modeling Identifies Key Determinants of Inhibitor Sensitivity in Breast Cancer Cell Lines.

Pathological assessment of resection specimens after neoadjuvant therapy for metastatic melanoma.

Clinical lymph node staging in colorectal cancer; a flip of the coin?

Loss of androgen receptor signaling in prostate cancer-associated fibroblasts (CAFs) promotes CCL2- and CXCL8-mediated cancer cell migration.

Tumor Resection Margin Definitions in Breast-Conserving Surgery: Systematic Review and Meta-analysis of the Current Literature.

Association between information provision and supportive care needs among ovarian cancer survivors: A cross-sectional study from the PROFILES registry.

Taking advantage of drug resistance, a new approach in the war on cancer.

Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells.

Sexual Functioning and Relationship Satisfaction of Partners of Breast Cancer Survivors Who Receive Internet-Based Sex Therapy.

Mitotic count can predict tamoxifen benefit in postmenopausal breast cancer patients while Ki67 score cannot.

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Metabolite profiling of the novel anti-cancer agent, plitidepsin, in urine and faeces in cancer patients after administration of ¹⁴C-plitidepsin.