Publications

British journal of clinical pharmacology

Therapeutic drug monitoring of small molecule kinase inhibitors in oncology in a real-world cohort study: does age matter?

International journal of care coordination

Turning teams and pathways into integrated practice units: Appearance characteristics and added value.

Acta oto-laryngologica

Direct complications and routine ICU admission after total laryngectomy.

Climacteric : the journal of the International Menopause Society

Does anti-Müllerian hormone predict change in menopausal symptoms following risk-reducing salpingo-oophorectomy? A prospective observational study.

Cancer metastasis reviews

Cancer-associated fibroblasts as key regulators of the breast cancer tumor microenvironment.

The oncologist

Cluster Analysis Demonstrates the Need to Individualize Care for Cancer Survivors.

Bioinformatics (Oxford, England)

Modelling signalling networks from perturbation data.

The Lancet. Oncology

Neoadjuvant chemotherapy with or without anthracyclines in the presence of dual HER2 blockade for HER2-positive breast cancer (TRAIN-2): a multicentre, open-label, randomised, phase 3 trial.

Annals of surgery

Surgicopathological Quality Control and Protocol Adherence to Lymphadenectomy in the CRITICS Gastric Cancer Trial.

JCO clinical cancer informatics

American Association for Cancer Research Project Genomics Evidence Neoplasia Information Exchange: From Inception to First Data Release and Beyond-Lessons Learned and Member Institutions' Perspectives.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Quantitative bioanalytical assay for the tropomyosin receptor kinase inhibitor larotrectinib in mouse plasma and tissue homogenates using liquid chromatography-tandem mass spectrometry.

Insights into imaging

Radiomics: a critical step towards integrated healthcare.

Reproductive sciences (Thousand Oaks, Calif.)

Acute Drug Effects on the Human Placental Tissue: The Development of a Placental Murine Xenograft Model.

Molecular & cellular proteomics : MCP

Doxorubicin-induced DNA Damage Causes Extensive Ubiquitination of Ribosomal Proteins Associated with a Decrease in Protein Translation.

Investigational new drugs

Translational PK-PD modeling analysis of MCLA-128, a HER2/HER3 bispecific monoclonal antibody, to predict clinical efficacious exposure and dose.

Breast (Edinburgh, Scotland)

Therapeutic Drug Monitoring of endoxifen as an alternative for CYP2D6 genotyping in individualizing tamoxifen therapy.

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Cancer survivors not participating in observational patient-reported outcome studies have a lower survival compared to participants: the population-based PROFILES registry.

International journal of computer assisted radiology and surgery

Accuracy assessment of wireless transponder tracking in the operating room environment.

British journal of clinical pharmacology

Food-effect study on uracil and dihydrouracil plasma levels as marker for dihydropyrimidine dehydrogenase activity in human volunteers.

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Identification and assessment of health-related quality of life issues in patients with sporadic desmoid-type fibromatosis: a literature review and focus group study.

Leukemia

Risk of subsequent myeloid neoplasms after radiotherapy treatment for a solid cancer among adults in the United States, 2000-2014.

Journal of pharmaceutical and biomedical analysis

Bioanalytical liquid chromatography-tandem mass spectrometric assay for the quantification of the ALK inhibitors alectinib, brigatinib and lorlatinib in plasma and mouse tissue homogenates.

30-11-2018

Nucleic acids research

Dot1 promotes H2B ubiquitination by a methyltransferase-independent mechanism.

30-11-2018

Genome medicine

A role for the unfolded protein response stress sensor ERN1 in regulating the response to MEK inhibitors in KRAS mutant colon cancers.

27-11-2018

Nature communications

Integrative epigenetic taxonomy of primary prostate cancer.

21-11-2018

Nature biotechnology

T cell receptor fingerprinting enables in-depth characterization of the interactions governing recognition of peptide-MHC complexes.

19-11-2018

Breast cancer research : BCR

Inflammation markers and cognitive performance in breast cancer survivors 20 years after completion of chemotherapy: a cohort study.

Key Publication

Clinical cancer research : an official journal of the American Association for Cancer Research

MELK Inhibition in Diffuse Intrinsic Pontine Glioma.

International journal of radiation oncology, biology, physics

Quantitative Imaging for Radiation Oncology.

International journal of radiation oncology, biology, physics

A Self-Sorting Coronal 4D-MRI Method for Daily Image Guidance of Liver Lesions on an MR-LINAC.

International journal of cancer

Detection of endogenously circulating mesenchymal stem cells in human cancer patients.

International journal of radiation oncology, biology, physics

Validating a Predictive Atlas of Tumor Shrinkage for Adaptive Radiotherapy of Locally Advanced Lung Cancer.

Clinical epidemiology

Comparing causes of death of Hodgkin lymphoma and breast cancer patients between medical records and cause-of-death statistics.

BMC cancer

International phase IV validation study of an EORTC quality of life questionnaire for testicular cancer patients: the EORTC QLQ-TC26.

12-11-2018

PloS one

Role of variant allele fraction and rare SNP filtering to improve cellular DNA repair endpoint association.

09-11-2018

The New England journal of medicine

Sunitinib Alone or after Nephrectomy in Renal Cancer.

08-11-2018

Science translational medicine

Enhanced detection of circulating tumor DNA by fragment size analysis.

07-11-2018

BMC cancer

(Cost-)effectiveness of an internet-based physical activity support program (with and without physiotherapy counselling) on physical activity levels of breast and prostate cancer survivors: design of the PABLO trial.

06-11-2018

Molecular pharmaceutics

ABCB1 Attenuates the Brain Penetration of the PARP Inhibitor AZD2461.

Journal of cell science

Mechanisms of integrin αVβ5 clustering in flat clathrin lattices.

Molecular pharmaceutics

P-Glycoprotein (MDR1/ABCB1) Restricts Brain Penetration of the Bruton's Tyrosine Kinase Inhibitor Ibrutinib, While Cytochrome P450-3A (CYP3A) Limits Its Oral Bioavailability.

The Journal of cell biology

Mapping 3D genome organization relative to nuclear compartments using TSA-Seq as a cytological ruler.

Nucleic acids research

A limited number of double-strand DNA breaks is sufficient to delay cell cycle progression.

02-11-2018

Abdominal radiology (New York)

Use of magnetic resonance imaging in rectal cancer patients: Society of Abdominal Radiology (SAR) rectal cancer disease-focused panel (DFP) recommendations 2017.

European journal of cancer (Oxford, England : 1990)

Cancer Core Europe: A European cancer research alliance realizing a research infrastructure with critical mass and programmatic approach to cure cancer in the 21st century.

Molecular oncology

FOXA1 levels are decreased in pleural breast cancer metastases after adjuvant endocrine therapy, and this is associated with poor outcome.

European journal of cancer (Oxford, England : 1990)

PanCareLIFE: The scientific basis for a European project to improve long-term care regarding fertility, ototoxicity and health-related quality of life after cancer occurring among children and adolescents.

European journal of cancer (Oxford, England : 1990)

Monitoring potentially modifiable lifestyle factors in cancer survivors: A narrative review on currently available methodologies and innovations for large-scale surveillance.

The Lancet. Oncology

DPYD genotype-guided dose individualisation of fluoropyrimidine therapy in patients with cancer: a prospective safety analysis.