Publications

Investigational new drugs

ATP-binding cassette transporters limit the brain penetration of Wee1 inhibitors.

01-06-2018

Journal of pharmacokinetics and pharmacodynamics

Pharmacodynamic modeling of cardiac biomarkers in breast cancer patients treated with anthracycline and trastuzumab regimens.

01-06-2018

European journal of human genetics : EJHG

The association between cancer family history and ovarian cancer risk in BRCA1/2 mutation carriers: can it be explained by the mutation position?

01-06-2018

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Survivorship care plans have a negative impact on long-term quality of life and anxiety through more threatening illness perceptions in gynecological cancer patients: the ROGY care trial.

01-06-2018

Cell

An Acquired Vulnerability of Drug-Resistant Melanoma with Therapeutic Potential.

31-05-2018

Journal of medical Internet research

Online Self-Administered Cognitive Testing Using the Amsterdam Cognition Scan: Establishing Psychometric Properties and Normative Data.

30-05-2018

Oncotarget

Sponge-supported cultures of primary head and neck tumors for an optimized preclinical model.

18-05-2018

Genes

Conventional Pathology Versus Gene Signatures for Assessing Luminal A and B Type Breast Cancers: Results of a Prospective Cohort Study.

17-05-2018

The EMBO journal

Anti-cancer therapy: senescence is the new black.

15-05-2018

Neuroepidemiology

Mild Cognitive Impairment and Dementia Show Contrasting Associations with Risk of Cancer.

15-05-2018

Immunity

Proteomic Analyses of Human Regulatory T Cells Reveal Adaptations in Signaling Pathways that Protect Cellular Identity.

15-05-2018

Cell reports

The CST Complex Mediates End Protection at Double-Strand Breaks and Promotes PARP Inhibitor Sensitivity in BRCA1-Deficient Cells.

15-05-2018

Scientific reports

Aurora kinase A (AURKA) interaction with Wnt and Ras-MAPK signalling pathways in colorectal cancer.

14-05-2018

Journal of medical Internet research

Barriers and Facilitators Affecting Patient Portal Implementation from an Organizational Perspective: Qualitative Study.

11-05-2018

The New England journal of medicine

Adjuvant Pembrolizumab versus Placebo in Resected Stage III Melanoma.

10-05-2018

Cell host & microbe

KREMEN1 Is a Host Entry Receptor for a Major Group of Enteroviruses.

09-05-2018

Nucleic acids research

LncRNA-OIS1 regulates DPP4 activation to modulate senescence induced by RAS.

04-05-2018

Journal of biomedical optics

Navigating surgical fluorescence cameras using near-infrared optical tracking.

01-05-2018

Bioorganic & medicinal chemistry letters

A multi-gram-scale stereoselective synthesis of Z-endoxifen.

01-05-2018

British journal of cancer

Ovarian stimulation for IVF and risk of primary breast cancer in BRCA1/2 mutation carriers.

01-05-2018

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Demographic, clinical, lifestyle-related, and social-cognitive correlates of physical activity in head and neck cancer survivors.

01-05-2018

Annals of surgery

Cause-specific Mortality in a Population-based Cohort of 9799 Women Treated for Ductal Carcinoma In Situ.

01-05-2018

The Lancet. Oncology

Chemotherapy versus chemoradiotherapy after surgery and preoperative chemotherapy for resectable gastric cancer (CRITICS): an international, open-label, randomised phase 3 trial.

01-05-2018

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Surgical morbidity and mortality after neoadjuvant chemotherapy in the CRITICS gastric cancer trial.

01-05-2018

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

A secondary analysis of FDG spatio-temporal consistency in the randomized phase II PET-boost trial in stage II-III NSCLC.

01-05-2018

European journal of radiology

CT texture analysis in colorectal liver metastases and the surrounding liver parenchyma and its potential as an imaging biomarker of disease aggressiveness, response and survival.

01-05-2018

The Laryngoscope

Development and external validation of a risk-prediction model to predict 5-year overall survival in advanced larynx cancer.

01-05-2018

Annals of oncology : official journal of the European Society for Medical Oncology

RAD51 foci as a functional biomarker of homologous recombination repair and PARP inhibitor resistance in germline BRCA-mutated breast cancer.

01-05-2018

Lung cancer (Amsterdam, Netherlands)

Physical behavior and associations with health outcomes in operable NSCLC patients: A prospective study.

01-05-2018

Angiogenesis

Platelet function is disturbed by the angiogenesis inhibitors sunitinib and sorafenib, but unaffected by bevacizumab.

01-05-2018

Clinical pharmacokinetics

Pharmacokinetic Optimization of Everolimus Dosing in Oncology: A Randomized Crossover Trial.

01-05-2018

The British journal of surgery

Association between hospital volume and quality of gastric cancer surgery in the CRITICS trial.

01-05-2018

Cancer chemotherapy and pharmacology

Phase I study of combined indomethacin and platinum-based chemotherapy to reduce platinum-induced fatty acids.

01-05-2018

Human mutation

The BRCA2 c.68-7T > A variant is not pathogenic: A model for clinical calibration of spliceogenicity.

01-05-2018

Immunology

The opposing roles of CD4⁺ T cells in anti-tumour immunity.

27-04-2018

Journal of extracellular vesicles

Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8.

27-04-2018

Scientific reports

E-cadherin breast tumor expression, risk factors and survival: Pooled analysis of 5,933 cases from 12 studies in the Breast Cancer Association Consortium.

26-04-2018

Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry

Trabecular Bone Score Is a Valuable Addition to Bone Mineral Density for Bone Quality Assessment in Older Mexican American Women With Type 2 Diabetes.

25-04-2018

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

American Society of Clinical Oncology Statement: Biosimilars in Oncology.

20-04-2018

Trials

ENdometrial cancer SURvivors' follow-up carE (ENSURE): Less is more? Evaluating patient satisfaction and cost-effectiveness of a reduced follow-up schedule: study protocol of a randomized controlled trial.

16-04-2018

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Bioanalytical assay for the quantification of the ALK inhibitor lorlatinib in mouse plasma using liquid chromatography-tandem mass spectrometry.

15-04-2018

PloS one

What drives centralisation in cancer care?

13-04-2018

Oncotarget

Precision cancer therapy: profiting from tumor specific defects in the DNA damage tolerance system.

10-04-2018

Cancer cell

T Cell Dysfunction in Cancer.

09-04-2018

Oncotarget

Fanconi anemia and homologous recombination gene variants are associated with functional DNA repair defects in vitro and poor outcome in patients with advanced head and neck squamous cell carcinoma.

06-04-2018

Molecular cell

ZUFSP Deubiquitylates K63-Linked Polyubiquitin Chains to Promote Genome Stability.

05-04-2018

The EMBO journal

Paligenosis: prepare to regenerate!

03-04-2018

BMJ open diabetes research & care

Mexican American and South Asian population-based cohorts reveal high prevalence of type 2 diabetes and crucial differences in metabolic phenotypes.

03-04-2018

JMIR cancer

Analysis of Content Shared in Online Cancer Communities: Systematic Review.

03-04-2018

Cell reports

Multifaceted Impact of MicroRNA 493-5p on Genome-Stabilizing Pathways Induces Platinum and PARP Inhibitor Resistance in BRCA2-Mutated Carcinomas.

03-04-2018