Publications

British journal of clinical pharmacology

A semi-mechanistic model based on glutathione depletion to describe intra-individual reduction in busulfan clearance.

01-08-2020

Molecular oncology

Towards a cancer mission in Horizon Europe: recommendations.

01-08-2020

Journal for immunotherapy of cancer

Tumor infiltrating lymphocytes (TIL) therapy in metastatic melanoma: boosting of neoantigen-specific T cell reactivity and long-term follow-up.

01-08-2020

The Lancet. Oncology

100 European core quality standards for cancer care and research centres.

01-08-2020

Acta oncologica (Stockholm, Sweden)

Health-related quality of life and symptom burden of epithelioid hemangioendothelioma patients: a global patient-driven Facebook study in a very rare malignancy.

01-08-2020

European urology oncology

Distribution of Molecular Subtypes in Muscle-invasive Bladder Cancer Is Driven by Sex-specific Differences.

01-08-2020

Nature genetics

The DNA methylation landscape of advanced prostate cancer.

01-08-2020

Annals of surgical oncology

Selection of Patients for Organ Preservation After Chemoradiotherapy: MRI Identifies Poor Responders Who Can Go Straight to Surgery.

01-08-2020

Genes & development

Cells of origin of lung cancers: lessons from mouse studies.

01-08-2020

Investigational new drugs

Phase I study of intermittent olaparib capsule or tablet dosing in combination with carboplatin and paclitaxel (part 2).

01-08-2020

Therapeutic drug monitoring

Evaluation of Extrapolation Methods to Predict Trough Concentrations to Guide Therapeutic Drug Monitoring of Oral Anticancer Drugs.

01-08-2020

Head & neck

Long-term swallowing, trismus, and speech outcomes after combined chemoradiotherapy and preventive rehabilitation for head and neck cancer; 10-year plus update.

01-08-2020

International journal of epidemiology

A Mendelian randomization analysis of circulating lipid traits and breast cancer risk.

01-08-2020

Breast (Edinburgh, Scotland)

The impact of menstruation persistence or recovery after chemotherapy on survival in young patients with hormone receptor negative breast cancer.

01-08-2020

Nature reviews. Immunology

Immune crosstalk in cancer progression and metastatic spread: a complex conversation.

01-08-2020

European journal of human genetics : EJHG

The uptake of predictive DNA testing in 40 families with a pathogenic BRCA1/BRCA2 variant. An evaluation of the proband-mediated procedure.

01-08-2020

Investigational new drugs

Phase I study of continuous olaparib capsule dosing in combination with carboplatin and/or paclitaxel (Part 1).

01-08-2020

Journal of medical genetics

Variants of uncertain clinical significance in hereditary breast and ovarian cancer genes: best practices in functional analysis for clinical annotation.

01-08-2020

Nature genetics

Prostate cancer reactivates developmental epigenomic programs during metastatic progression.

01-08-2020

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Feasibility of cone beam CT-guided library of plans strategy in pre-operative gastric cancer radiotherapy.

01-08-2020

Nucleosides, nucleotides & nucleic acids

Effect of dexamethasone on the antileukemic effect of cytarabine: role of deoxycytidine kinase.

31-07-2020

BMC cancer

Evaluating different adoption scenarios for TIL-therapy and the influence on its (early) cost-effectiveness.

31-07-2020

Cancers

The Perceived Impact of Length of the Diagnostic Pathway Is Associated with Health-Related Quality of Life of Sarcoma Survivors: Results from the Dutch Nationwide SURVSARC Study.

28-07-2020

Cancers

Age Does Matter in Adolescents and Young Adults versus Older Adults with Advanced Melanoma; A National Cohort Study Comparing Tumor Characteristics, Treatment Pattern, Toxicity and Response.

27-07-2020

Breast cancer research : BCR

BRCAness digitalMLPA profiling predicts benefit of intensified platinum-based chemotherapy in triple-negative and luminal-type breast cancer.

25-07-2020

Cell reports

Calorie Restriction Increases the Number of Competing Stem Cells and Decreases Mutation Retention in the Intestine.

21-07-2020

Proceedings of the National Academy of Sciences of the United States of America

Stem cell lineage survival as a noisy competition for niche access.

21-07-2020

Trials

Internet-based cognitive rehabilitation for WORking Cancer survivors (i-WORC): study protocol of a randomized controlled trial.

20-07-2020

Molecular cell

RNA Pol II Length and Disorder Enable Cooperative Scaling of Transcriptional Bursting.

16-07-2020

Insights into imaging

Follow-up after radiological intervention in oncology: ECIO-ESOI evidence and consensus-based recommendations for clinical practice.

16-07-2020

Science translational medicine

Dynamic changes in glioma macrophage populations after radiotherapy reveal CSF-1R inhibition as a strategy to overcome resistance.

15-07-2020

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Bioanalytical method for the simultaneous quantification of irinotecan and its active metabolite SN-38 in mouse plasma and tissue homogenates using HPLC-fluorescence.

15-07-2020

The Journal of biological chemistry

Cryo-electron microscopy structure and potential enzymatic function of human six-transmembrane epithelial antigen of the prostate 1 (STEAP1).

10-07-2020

ACS infectious diseases

A Supramolecular Platform Technology for Bacterial Cell Surface Modification.

10-07-2020

PloS one

Kinome capture sequencing of high-grade serous ovarian carcinoma reveals novel mutations in the JAK3 gene.

09-07-2020

BMC cancer

Design of the PROstate cancer follow-up care in Secondary and Primary hEalth Care study (PROSPEC): a randomized controlled trial to evaluate the effectiveness of primary care-based follow-up of localized prostate cancer survivors.

08-07-2020

Journal of translational medicine

Presence of a 34-gene signature is a favorable prognostic marker in squamous non-small cell lung carcinoma.

03-07-2020

Nature communications

Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers.

03-07-2020

Scientific reports

Epigenetic profiling demarcates molecular subtypes of muscle-invasive bladder cancer.

02-07-2020

Nature medicine

Author Correction: Caring for patients with cancer in the COVID-19 era.

01-07-2020

Molecular cancer research : MCR

The NF-κB Pathway Promotes Tamoxifen Tolerance and Disease Recurrence in Estrogen Receptor-Positive Breast Cancers.

01-07-2020

Cardiovascular and interventional radiology

Percutaneous Microwave Ablation of Histologically Proven T1 Renal Cell Carcinoma.

01-07-2020

Cancer chemotherapy and pharmacology

Correction to: Exposure-survival analyses of pazopanib in renal cell carcinoma and soft tissue sarcoma patients: opportunities for dose optimization.

01-07-2020

Nature cancer

Publisher Correction: Long-distance modulation of bystander tumor cells by CD8⁺ T-cell-secreted IFN-γ.

01-07-2020

Nature medicine

Support systems to guide clinical decision-making in precision oncology: The Cancer Core Europe Molecular Tumor Board Portal.

01-07-2020

JAMA network open

Association of Image-Guided Navigation With Complete Resection Rate in Patients With Locally Advanced Primary and Recurrent Rectal Cancer: A Nonrandomized Controlled Trial.

01-07-2020

JAMA oncology

De-Escalating Breast Cancer Surgery for Low-Risk Ductal Carcinoma in Situ.

01-07-2020

Clinical pharmacokinetics

Cost-Neutral Optimization of Pazopanib Exposure by Splitting Intake Moments: A Prospective Pharmacokinetic Study in Cancer Patients.

01-07-2020

Journal of cancer research and clinical oncology

Olaparib and temozolomide in desmoplastic small round cell tumors: a promising combination in vitro and in vivo.

01-07-2020

International journal of radiation oncology, biology, physics

Correlating Dose Variables with Local Tumor Control in Stereotactic Body Radiation Therapy for Early-Stage Non-Small Cell Lung Cancer: A Modeling Study on 1500 Individual Treatments.

01-07-2020