Publications

Nature

Single-cell spatial immune landscapes of primary and metastatic brain tumours.

01-02-2023

Nature methods

AlphaFill: enriching AlphaFold models with ligands and cofactors.

01-02-2023

Journal of robotic surgery

Click-on fluorescence detectors: using robotic surgical instruments to characterize molecular tissue aspects.

01-02-2023

Clinical and translational science

A naïve pooled data approach for extrapolation of Phase 0 microdose trials to therapeutic dosing regimens.

01-02-2023

Urologic oncology

Predictive value of low testosterone concentrations during and prior to enzalutamide treatment in metastatic castration-resistant prostate cancer.

01-02-2023

British journal of clinical pharmacology

Prediction of the pharmacokinetics of pemetrexed with a low test dose: A proof-of-concept study.

01-02-2023

Anti-cancer drugs

Time above threshold plasma concentrations as pharmacokinetic parameter in the comparison of oral and intravenous docetaxel treatment of breast cancer tumors.

01-02-2023

Cancer medicine

Risk of metachronous contralateral breast cancer in patients with primary invasive lobular breast cancer: Results from a nationwide cohort.

01-02-2023

Journal of cancer survivorship : research and practice

Self-reported causes of cancer among 6881 survivors with 6 tumour types: results from the PROFILES registry.

01-02-2023

Acta pharmaceutica Sinica. B

Carboxylesterase 1 family knockout alters drug disposition and lipid metabolism.

01-02-2023

Clinical cancer research : an official journal of the American Association for Cancer Research

[89Zr]Zr-DFO-girentuximab and [18F]FDG PET/CT to Predict Watchful Waiting Duration in Patients with Metastatic Clear-cell Renal Cell Carcinoma.

01-02-2023

Nature reviews. Cancer

Author Correction: Learning to distinguish progressive and non-progressive ductal carcinoma in situ.

01-02-2023

European urology open science

Current Routine Testosterone Immunoassays Are Unsuitable for Lowering the General Castration Cutoff Recommendation to <0.7 nmol/l (20 ng/dl).

01-02-2023

EClinicalMedicine

Desmoid is not a sarcoma; reply to Sachdev et al.

01-02-2023

European journal of cancer (Oxford, England : 1990)

Controversies in the management of patients with soft tissue sarcoma: Recommendations of the Conference on State of Science in Sarcoma 2022.

01-02-2023

Clinical pharmacology and therapeutics

Prediction of Busulfan Clearance by Predose Plasma Metabolomic Profiling.

01-02-2023

Molecular imaging and biology

Quantifying the Impact of Signal-to-background Ratios on Surgical Discrimination of Fluorescent Lesions.

01-02-2023

European urology oncology

Role of Local and/or Metastasis-directed Therapy in Patients with Hormone-sensitive M1a Prostate Cancer-A Systematic Review.

01-02-2023

Melanoma research

MeVa2.1.dOVA and MeVa2.2.dOVA: two novel BRAFV600E-driven mouse melanoma cell lines to study tumor immune resistance.

01-02-2023

Nature reviews. Genetics

New insights into genome folding by loop extrusion from inducible degron technologies.

01-02-2023

Nature communications

Author Correction: Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features.

31-01-2023

Frontiers in pharmacology

Genome-wide analyses of platinum-induced ototoxicity in childhood cancer patients: Results of GO-CAT and United Kingdom MAGIC consortia.

27-01-2023

Frontiers in immunology

Huwe1 supports B-cell development, B-cell-dependent immunity, somatic hypermutation and class switch recombination by regulating proliferation.

27-01-2023

Value Health.

Cost-Effectiveness and Budget Impact of Future Developments With Whole-Genome Sequencing for Patients With Lung Cancer

26-01-2023

Key Publication

Genome medicine

Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry.

26-01-2023

Nature communications

Author Correction: Federated learning enables big data for rare cancer boundary detection.

26-01-2023

J Mol Diagn.

A Micro-Costing Framework for Circulating Tumor DNA Testing in Dutch Clinical Practice

25-01-2023

Key Publication

Proceedings of the National Academy of Sciences of the United States of America

Mammalian life depends on two distinct pathways of DNA damage tolerance.

24-01-2023

Journal of medical systems

Detecting Patient Deterioration Early Using Continuous Heart rate and Respiratory rate Measurements in Hospitalized COVID-19 Patients.

24-01-2023

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

FORT-1: Phase II/III Study of Rogaratinib Versus Chemotherapy in Patients With Locally Advanced or Metastatic Urothelial Carcinoma Selected Based on FGFR1/3 mRNA Expression.

20-01-2023

Cell

Coordinated cancer chaos.

19-01-2023

Cell chemical biology

Autotaxin facilitates selective LPA receptor signaling.

19-01-2023

eLife

Ras/MAPK signalling intensity defines subclonal fitness in a mouse model of hepatocellular carcinoma.

19-01-2023

Insights into imaging

MRI anatomy of the rectum: key concepts important for rectal cancer staging and treatment planning.

18-01-2023

Insights into imaging

Multi-modal artificial intelligence for the combination of automated 3D breast ultrasound and mammograms in a population of women with predominantly dense breasts.

16-01-2023

Clinica chimica acta; international journal of clinical chemistry

Serum testosterone measured by liquid chromatography-tandem mass spectrometry is an independent predictor of response to castration in metastatic hormone-sensitive prostate cancer.

15-01-2023

Nature communications

CD4⁺ helper T cells endow cDC1 with cancer-impeding functions in the human tumor micro-environment.

13-01-2023

Communications biology

Genome-wide siRNA screens identify RBBP9 function as a potential target in Fanconi anaemia-deficient head-and-neck squamous cell carcinoma.

13-01-2023

Nature communications

CD26-negative and CD26-positive tissue-resident fibroblasts contribute to functionally distinct CAF subpopulations in breast cancer.

12-01-2023

Cancer cell

IL-5-producing CD4⁺ T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer.

09-01-2023

Cancers

Adjuvant BRAF-MEK Inhibitors versus Anti PD-1 Therapy in Stage III Melanoma: A Propensity-Matched Outcome Analysis.

07-01-2023

BMC cancer

High-dose chemotherapy with stem cell rescue to treat stage III homologous deficient breast cancer: factors influencing clinical implementation.

07-01-2023

Journal of proteome research

Multiomics of Colorectal Cancer Organoids Reveals Putative Mediators of Cancer Progression Resulting from SMAD4 Inactivation.

06-01-2023

Neuro-oncology

Hippocampal avoidance prophylactic cranial irradiation (HA-PCI) for small cell lung cancer reduces hippocampal atrophy compared to conventional PCI.

05-01-2023

Frontiers in psychology

"Double awareness"-adolescents and young adults coping with an uncertain or poor cancer prognosis: A qualitative study.

03-01-2023

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

Psychological impact of referral to an oncology hospital on patients with an ovarian mass.

03-01-2023

International journal of molecular sciences

Chromosomal Rearrangements and Chromothripsis: The Alternative End Generation Model.

02-01-2023

Acta oncologica (Stockholm, Sweden)

Evaluating comprehensive cancer networks; a review of standards and evaluation methods for care networks to inform a comparison with the OECI comprehensive cancer network standards.

01-01-2023

European journal of cancer (Oxford, England : 1990)

Comprehensive molecular profiling of sarcomas in adolescent and young adult patients: Results of the EORTC SPECTA-AYA international proof-of-concept study.

01-01-2023

Cancer chemotherapy and pharmacology

Renal function-based versus standard dosing of pemetrexed: a randomized controlled trial.

01-01-2023

Single-cell spatial immune landscapes of primary and metastatic brain tumours.

AlphaFill: enriching AlphaFold models with ligands and cofactors.

Click-on fluorescence detectors: using robotic surgical instruments to characterize molecular tissue aspects.

A naïve pooled data approach for extrapolation of Phase 0 microdose trials to therapeutic dosing regimens.

Predictive value of low testosterone concentrations during and prior to enzalutamide treatment in metastatic castration-resistant prostate cancer.

Prediction of the pharmacokinetics of pemetrexed with a low test dose: A proof-of-concept study.

Time above threshold plasma concentrations as pharmacokinetic parameter in the comparison of oral and intravenous docetaxel treatment of breast cancer tumors.

Risk of metachronous contralateral breast cancer in patients with primary invasive lobular breast cancer: Results from a nationwide cohort.

Self-reported causes of cancer among 6881 survivors with 6 tumour types: results from the PROFILES registry.

Carboxylesterase 1 family knockout alters drug disposition and lipid metabolism.

[89Zr]Zr-DFO-girentuximab and [18F]FDG PET/CT to Predict Watchful Waiting Duration in Patients with Metastatic Clear-cell Renal Cell Carcinoma.

Author Correction: Learning to distinguish progressive and non-progressive ductal carcinoma in situ.

Current Routine Testosterone Immunoassays Are Unsuitable for Lowering the General Castration Cutoff Recommendation to <0.7 nmol/l (20 ng/dl).

Desmoid is not a sarcoma; reply to Sachdev et al.

Controversies in the management of patients with soft tissue sarcoma: Recommendations of the Conference on State of Science in Sarcoma 2022.

Prediction of Busulfan Clearance by Predose Plasma Metabolomic Profiling.

Quantifying the Impact of Signal-to-background Ratios on Surgical Discrimination of Fluorescent Lesions.

Role of Local and/or Metastasis-directed Therapy in Patients with Hormone-sensitive M1a Prostate Cancer-A Systematic Review.

MeVa2.1.dOVA and MeVa2.2.dOVA: two novel BRAFV600E-driven mouse melanoma cell lines to study tumor immune resistance.

New insights into genome folding by loop extrusion from inducible degron technologies.

Author Correction: Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features.

Genome-wide analyses of platinum-induced ototoxicity in childhood cancer patients: Results of GO-CAT and United Kingdom MAGIC consortia.

Huwe1 supports B-cell development, B-cell-dependent immunity, somatic hypermutation and class switch recombination by regulating proliferation.

Cost-Effectiveness and Budget Impact of Future Developments With Whole-Genome Sequencing for Patients With Lung Cancer

Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry.

Author Correction: Federated learning enables big data for rare cancer boundary detection.

A Micro-Costing Framework for Circulating Tumor DNA Testing in Dutch Clinical Practice

Mammalian life depends on two distinct pathways of DNA damage tolerance.

Detecting Patient Deterioration Early Using Continuous Heart rate and Respiratory rate Measurements in Hospitalized COVID-19 Patients.

FORT-1: Phase II/III Study of Rogaratinib Versus Chemotherapy in Patients With Locally Advanced or Metastatic Urothelial Carcinoma Selected Based on FGFR1/3 mRNA Expression.

Coordinated cancer chaos.

Autotaxin facilitates selective LPA receptor signaling.

Ras/MAPK signalling intensity defines subclonal fitness in a mouse model of hepatocellular carcinoma.

MRI anatomy of the rectum: key concepts important for rectal cancer staging and treatment planning.

Multi-modal artificial intelligence for the combination of automated 3D breast ultrasound and mammograms in a population of women with predominantly dense breasts.

Serum testosterone measured by liquid chromatography-tandem mass spectrometry is an independent predictor of response to castration in metastatic hormone-sensitive prostate cancer.

CD4+ helper T cells endow cDC1 with cancer-impeding functions in the human tumor micro-environment.

Genome-wide siRNA screens identify RBBP9 function as a potential target in Fanconi anaemia-deficient head-and-neck squamous cell carcinoma.

CD26-negative and CD26-positive tissue-resident fibroblasts contribute to functionally distinct CAF subpopulations in breast cancer.

IL-5-producing CD4+ T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer.

Adjuvant BRAF-MEK Inhibitors versus Anti PD-1 Therapy in Stage III Melanoma: A Propensity-Matched Outcome Analysis.

High-dose chemotherapy with stem cell rescue to treat stage III homologous deficient breast cancer: factors influencing clinical implementation.

Multiomics of Colorectal Cancer Organoids Reveals Putative Mediators of Cancer Progression Resulting from SMAD4 Inactivation.

Hippocampal avoidance prophylactic cranial irradiation (HA-PCI) for small cell lung cancer reduces hippocampal atrophy compared to conventional PCI.

"Double awareness"-adolescents and young adults coping with an uncertain or poor cancer prognosis: A qualitative study.

Psychological impact of referral to an oncology hospital on patients with an ovarian mass.

Chromosomal Rearrangements and Chromothripsis: The Alternative End Generation Model.

Evaluating comprehensive cancer networks; a review of standards and evaluation methods for care networks to inform a comparison with the OECI comprehensive cancer network standards.

Comprehensive molecular profiling of sarcomas in adolescent and young adult patients: Results of the EORTC SPECTA-AYA international proof-of-concept study.

Renal function-based versus standard dosing of pemetrexed: a randomized controlled trial.

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CD4⁺ helper T cells endow cDC1 with cancer-impeding functions in the human tumor micro-environment.

IL-5-producing CD4⁺ T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer.