Publications

Clinical pharmacokinetics

Semi-physiological Enriched Population Pharmacokinetic Modelling to Predict the Effects of Pregnancy on the Pharmacokinetics of Cytotoxic Drugs.

01-08-2023

Cancer medicine

Association of the CHEK2 c.1100delC variant, radiotherapy, and systemic treatment with contralateral breast cancer risk and breast cancer-specific survival.

01-08-2023

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

From once-weekly to semi-weekly whole prostate gland stereotactic radiotherapy with focal boosting: Primary endpoint analysis of the multicenter phase II hypo-FLAME 2.0 trial.

01-08-2023

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Natural deletion of mouse carboxylesterases Ces1c/d/e impacts drug metabolism and metabolic syndrome development.

01-08-2023

Die Pharmazie

Development of a UPLC-MS/MS Assay for the Quantitative Determination of Capecitabine, 5'-deoxy-5-fluorocytidine (5'-dFCR), 5'-deoxy-5-fluorouridine (5'-dFUR), 5'-fluorouracil (5-FU), and α-fluoro-β-alanine (FBAL).

01-08-2023

Patient education and counseling

Effects of a pre-visit online information tool about genetic counselling for ovarian cancer patients, a randomized controlled trial.

01-08-2023

Biomedical optics express

Diffuse reflectance spectroscopy for accurate margin assessment in breast-conserving surgeries: importance of an optimal number of fibers.

01-08-2023

BJU international

Prognostic impact of variant histologies in urothelial bladder cancer treated with radical cystectomy.

01-08-2023

CPT: pharmacometrics & systems pharmacology

Population pharmacokinetic dosimetry model using imaging data to assess variability in pharmacokinetics of ¹⁷⁷ Lu-PSMA-617 in prostate cancer patients.

01-08-2023

Journal of cancer survivorship : research and practice

Phase III study of the European Organisation for Research and Treatment of Cancer Quality of Life cancer survivorship core questionnaire.

01-08-2023

Pharmaceutical research

P-glycoprotein (MDR1/ABCB1) Restricts Brain Penetration of the Main Active Heroin Metabolites 6-monoacetylmorphine (6-MAM) and Morphine in Mice.

01-08-2023

European urology open science

State of the Art in Prostate-specific Membrane Antigen-targeted Surgery-A Systematic Review.

01-08-2023

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

The current use of the EORTC QLQ-NMIBC24 and QLQ-BLM30 questionnaires for the assessment of health-related quality of life in bladder cancer patients: a systematic review.

01-08-2023

Clinical and translational medicine

MIND the translational gap: Preclinical models of ductal carcinoma in situ.

01-08-2023

The Journal of pathology

Multiscale deep learning framework captures systemic immune features in lymph nodes predictive of triple negative breast cancer outcome in large-scale studies.

01-08-2023

Cancer research communications

Exploring the Onset and Progression of Prostate Cancer through a Multicellular Agent-based Model.

01-08-2023

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

In Response to Arcidiacono et al.: "Should dose intensification be discontinued or should accelerated schemes remain an important area of clinical research?".

01-08-2023

Nature

cGAS-STING drives ageing-related inflammation and neurodegeneration.

01-08-2023

The Journal of pathology

Spatial analyses of immune cell infiltration in cancer: current methods and future directions: A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer.

01-08-2023

The Journal of pathology

Pitfalls in machine learning-based assessment of tumor-infiltrating lymphocytes in breast cancer: A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer.

01-08-2023

Drug discovery today

Targeted combination therapies in oncology: Challenging regulatory frameworks designed for monotherapies in Europe.

01-08-2023

Clinical pharmacokinetics

CYP3A4*22 Genotype-Guided Dosing of Kinase Inhibitors in Cancer Patients.

01-08-2023

ESMO open

Factors associated with long-term antibody response after COVID-19 vaccination in patients treated with systemic treatment for solid tumors.

01-08-2023

European journal of cancer (Oxford, England : 1990)

Prognostic and predictive value of metformin in the European Organisation for Research and Treatment of Cancer 1325/KEYNOTE-054 phase III trial of pembrolizumab versus placebo in resected high-risk stage III melanoma.

01-08-2023

JAMA network open

Incidence, Stage, Treatment, and Survival of Noncardia Gastric Cancer.

01-08-2023

The Lancet. Oncology

Common Sense Oncology: outcomes that matter.

01-08-2023

Acta oncologica (Stockholm, Sweden)

Involving adolescents and young adults (AYA) with an uncertain or poor cancer prognosis as research partners.

01-08-2023

Breast (Edinburgh, Scotland)

Unleashing NK- and CD8 T cells by combining monalizumab and trastuzumab for metastatic HER2-positive breast cancer: Results of the MIMOSA trial.

01-08-2023

Virchows Archiv : an international journal of pathology

Reliability of whole mount radical prostatectomy histopathology as the ground truth for artificial intelligence assisted prostate imaging.

01-08-2023

Annals of surgical oncology

Oncological Outcome After Lymph Node Dissection for Cutaneous Squamous Cell Carcinoma.

01-08-2023

Nature communications

Obesity-associated changes in molecular biology of primary breast cancer.

21-07-2023

Insights into imaging

Radiomic signatures from T2W and DWI MRI are predictive of tumour hypoxia in colorectal liver metastases.

21-07-2023

Journal of patient-reported outcomes

Monitoring aerobic capacity in cancer survivors using self-reported questionnaires: criterion validity and responsiveness.

19-07-2023

International journal of cancer

Adjuvant treatment of in-transit melanoma: Narrowing the knowledge gap left by clinical trials.

15-07-2023

Journal of mammary gland biology and neoplasia

Imagine beyond: recent breakthroughs and next challenges in mammary gland biology and breast cancer research.

14-07-2023

The New England journal of medicine

Third-Line Therapy in Metastatic Colorectal Cancer.

13-07-2023

Thyroid research

Determinants and mediating mechanisms of quality of life and disease-specific symptoms among thyroid cancer patients: the design of the WaTCh study.

10-07-2023

International journal of molecular sciences

A C57BL/6J Fancg-KO Mouse Model Generated by CRISPR/Cas9 Partially Captures the Human Phenotype.

05-07-2023

Clinical cancer research : an official journal of the American Association for Cancer Research

Facts and Hopes in Immunotherapy for Early-Stage Triple-Negative Breast Cancer.

05-07-2023

The oncologist

Beyond Skin Rash: Alpelisib-Induced Anaphylactic Reactions.

05-07-2023

Frontiers in immunology

Heterogeneity in functional genetic screens: friend or foe?

03-07-2023

Bioinformatics advances

snHiC: a complete and simplified snakemake pipeline for grouped Hi-C data analysis.

03-07-2023

Journal for immunotherapy of cancer

IMPemBra: a phase 2 study comparing pembrolizumab with intermittent/short-term dual MAPK pathway inhibition plus pembrolizumab in patients with melanoma harboring the BRAFV600 mutation.

01-07-2023

European journal of nuclear medicine and molecular imaging

A hybrid radioactive and fluorescence approach is more than the sum of its parts; outcome of a phase II randomized sentinel node trial in prostate cancer patients.

01-07-2023

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Design and statistics of pharmacokinetic drug-drug, herb-drug, and food-drug interaction studies in oncology patients.

01-07-2023

Gynecologic oncology

WEE1 inhibitor adavosertib in combination with carboplatin in advanced TP53 mutated ovarian cancer: A biomarker-enriched phase II study.

01-07-2023

Nature

Heritable transcriptional defects from aberrations of nuclear architecture.

01-07-2023

Clinical pharmacokinetics

Predicting Chemotherapy Distribution into Breast Milk for Breastfeeding Women Using a Population Pharmacokinetic Approach.

01-07-2023

European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society

Health-related quality of life of children with neurofibromatosis type 1: Analysis of proxy-rated PedsQL and CHQ questionnaires.

01-07-2023

The Lancet. Oncology

Adjuvant immune checkpoint blockade revisited.

01-07-2023

Semi-physiological Enriched Population Pharmacokinetic Modelling to Predict the Effects of Pregnancy on the Pharmacokinetics of Cytotoxic Drugs.

Association of the CHEK2 c.1100delC variant, radiotherapy, and systemic treatment with contralateral breast cancer risk and breast cancer-specific survival.

From once-weekly to semi-weekly whole prostate gland stereotactic radiotherapy with focal boosting: Primary endpoint analysis of the multicenter phase II hypo-FLAME 2.0 trial.

Natural deletion of mouse carboxylesterases Ces1c/d/e impacts drug metabolism and metabolic syndrome development.

Development of a UPLC-MS/MS Assay for the Quantitative Determination of Capecitabine, 5'-deoxy-5-fluorocytidine (5'-dFCR), 5'-deoxy-5-fluorouridine (5'-dFUR), 5'-fluorouracil (5-FU), and α-fluoro-β-alanine (FBAL).

Effects of a pre-visit online information tool about genetic counselling for ovarian cancer patients, a randomized controlled trial.

Diffuse reflectance spectroscopy for accurate margin assessment in breast-conserving surgeries: importance of an optimal number of fibers.

Prognostic impact of variant histologies in urothelial bladder cancer treated with radical cystectomy.

Population pharmacokinetic dosimetry model using imaging data to assess variability in pharmacokinetics of 177 Lu-PSMA-617 in prostate cancer patients.

Phase III study of the European Organisation for Research and Treatment of Cancer Quality of Life cancer survivorship core questionnaire.

P-glycoprotein (MDR1/ABCB1) Restricts Brain Penetration of the Main Active Heroin Metabolites 6-monoacetylmorphine (6-MAM) and Morphine in Mice.

State of the Art in Prostate-specific Membrane Antigen-targeted Surgery-A Systematic Review.

The current use of the EORTC QLQ-NMIBC24 and QLQ-BLM30 questionnaires for the assessment of health-related quality of life in bladder cancer patients: a systematic review.

MIND the translational gap: Preclinical models of ductal carcinoma in situ.

Multiscale deep learning framework captures systemic immune features in lymph nodes predictive of triple negative breast cancer outcome in large-scale studies.

Exploring the Onset and Progression of Prostate Cancer through a Multicellular Agent-based Model.

In Response to Arcidiacono et al.: "Should dose intensification be discontinued or should accelerated schemes remain an important area of clinical research?".

cGAS-STING drives ageing-related inflammation and neurodegeneration.

Spatial analyses of immune cell infiltration in cancer: current methods and future directions: A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer.

Pitfalls in machine learning-based assessment of tumor-infiltrating lymphocytes in breast cancer: A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer.

Targeted combination therapies in oncology: Challenging regulatory frameworks designed for monotherapies in Europe.

CYP3A4*22 Genotype-Guided Dosing of Kinase Inhibitors in Cancer Patients.

Factors associated with long-term antibody response after COVID-19 vaccination in patients treated with systemic treatment for solid tumors.

Prognostic and predictive value of metformin in the European Organisation for Research and Treatment of Cancer 1325/KEYNOTE-054 phase III trial of pembrolizumab versus placebo in resected high-risk stage III melanoma.

Incidence, Stage, Treatment, and Survival of Noncardia Gastric Cancer.

Common Sense Oncology: outcomes that matter.

Involving adolescents and young adults (AYA) with an uncertain or poor cancer prognosis as research partners.

Unleashing NK- and CD8 T cells by combining monalizumab and trastuzumab for metastatic HER2-positive breast cancer: Results of the MIMOSA trial.

Reliability of whole mount radical prostatectomy histopathology as the ground truth for artificial intelligence assisted prostate imaging.

Oncological Outcome After Lymph Node Dissection for Cutaneous Squamous Cell Carcinoma.

Obesity-associated changes in molecular biology of primary breast cancer.

Radiomic signatures from T2W and DWI MRI are predictive of tumour hypoxia in colorectal liver metastases.

Monitoring aerobic capacity in cancer survivors using self-reported questionnaires: criterion validity and responsiveness.

Adjuvant treatment of in-transit melanoma: Narrowing the knowledge gap left by clinical trials.

Imagine beyond: recent breakthroughs and next challenges in mammary gland biology and breast cancer research.

Third-Line Therapy in Metastatic Colorectal Cancer.

Determinants and mediating mechanisms of quality of life and disease-specific symptoms among thyroid cancer patients: the design of the WaTCh study.

A C57BL/6J Fancg-KO Mouse Model Generated by CRISPR/Cas9 Partially Captures the Human Phenotype.

Facts and Hopes in Immunotherapy for Early-Stage Triple-Negative Breast Cancer.

Beyond Skin Rash: Alpelisib-Induced Anaphylactic Reactions.

Heterogeneity in functional genetic screens: friend or foe?

snHiC: a complete and simplified snakemake pipeline for grouped Hi-C data analysis.

IMPemBra: a phase 2 study comparing pembrolizumab with intermittent/short-term dual MAPK pathway inhibition plus pembrolizumab in patients with melanoma harboring the BRAFV600 mutation.

A hybrid radioactive and fluorescence approach is more than the sum of its parts; outcome of a phase II randomized sentinel node trial in prostate cancer patients.

Design and statistics of pharmacokinetic drug-drug, herb-drug, and food-drug interaction studies in oncology patients.

WEE1 inhibitor adavosertib in combination with carboplatin in advanced TP53 mutated ovarian cancer: A biomarker-enriched phase II study.

Heritable transcriptional defects from aberrations of nuclear architecture.

Predicting Chemotherapy Distribution into Breast Milk for Breastfeeding Women Using a Population Pharmacokinetic Approach.

Health-related quality of life of children with neurofibromatosis type 1: Analysis of proxy-rated PedsQL and CHQ questionnaires.

Adjuvant immune checkpoint blockade revisited.

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Population pharmacokinetic dosimetry model using imaging data to assess variability in pharmacokinetics of ¹⁷⁷ Lu-PSMA-617 in prostate cancer patients.