Publications

Cancers

A Survival Tree of Advanced Melanoma Patients with Brain Metastases Treated with Immune Checkpoint Inhibitors.

26-05-2023

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Psychological and social challenges of patients with locally advanced and metastatic gastrointestinal stromal tumours (GIST) on long-term treatment with tyrosine kinase inhibitors: a qualitative study with patients and medical oncologists.

26-05-2023

Molecular cell

DNA supercoiling restricts the transcriptional bursting of neighboring eukaryotic genes.

18-05-2023

Micromachines

Microcamera Visualisation System to Overcome Specular Reflections for Tissue Imaging.

17-05-2023

The British journal of surgery

Oncological surgery follow-up and quality of life: meta-analysis.

16-05-2023

BMC medical research methodology

The Trial within Cohorts (TwiCs) study design in oncology: experience and methodological reflections.

13-05-2023

NPJ breast cancer

Immune landscape of breast tumors with low and intermediate estrogen receptor expression.

13-05-2023

NPJ breast cancer

PREDICT validity for prognosis of breast cancer patients with pathogenic BRCA1/2 variants.

12-05-2023

Pharmaceutics

Optimization of a Quantitative Anti-Drug Antibodies against Infliximab Assay with the Liquid Chromatography-Tandem Mass Spectrometry: A Method Validation Study and Future Perspectives.

12-05-2023

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

High-Grade Serous Carcinoma at Risk-Reducing Salpingo-Oophorectomy in Asymptomatic Carriers of BRCA1/2 Pathogenic Variants: Prevalence and Clinical Factors.

10-05-2023

Cancers

Tissue Classification of Breast Cancer by Hyperspectral Unmixing.

09-05-2023

Breast cancer research : BCR

Breast cancer genomes from CHEK2 c.1100delC mutation carriers lack somatic TP53 mutations and display a unique structural variant size distribution profile.

09-05-2023

Cancer cell

A living biobank of patient-derived ductal carcinoma in situ mouse-intraductal xenografts identifies risk factors for invasive progression.

08-05-2023

Breast cancer research : BCR

Systematic screening identifies ABCG2 as critical factor underlying synergy of kinase inhibitors with transcriptional CDK inhibitors.

05-05-2023

Molecular cell

PRC2.1- and PRC2.2-specific accessory proteins drive recruitment of different forms of canonical PRC1.

04-05-2023

Cold Spring Harbor perspectives in medicine

Multidimensional Imaging of Breast Cancer.

02-05-2023

PloS one

A deep learning-based application for COVID-19 diagnosis on CT: The Imaging COVID-19 AI initiative.

02-05-2023

Clinical and translational medicine

Drug-drug synthetic lethality to combat cancer: From bench to bedside.

01-05-2023

Nature structural & molecular biology

Dynamic epistasis analysis reveals how chromatin remodeling regulates transcriptional bursting.

01-05-2023

European journal of cancer (Oxford, England : 1990)

Definition, diagnosis and treatment of oligometastatic oesophagogastric cancer: A Delphi consensus study in Europe.

01-05-2023

EClinicalMedicine

Influence of germline variations in drug transporters ABCB1 and ABCG2 on intracerebral osimertinib efficacy in patients with non-small cell lung cancer.

01-05-2023

Pharmaceutical research

Exposure-Response Analyses of Olaparib in Real-Life Patients with Ovarian Cancer.

01-05-2023

Molecular pharmaceutics

Enhancement of the Oral Availability of Cabazitaxel Using the Cytochrome P450 3A (CYP3A) Inhibitor Ritonavir in Mice.

01-05-2023

Pediatric blood & cancer

Clinical evaluation of late outcomes in Dutch childhood cancer survivors: Methodology of the DCCSS LATER 2 study.

01-05-2023

Veterinary pathology

Spontaneous early-onset neurodegeneration in the brainstem and spinal cord of NSG, NOG, and NXG mice.

01-05-2023

Haematologica

Pathology review identifies frequent misdiagnoses in recurrent classic Hodgkin lymphoma in a nationwide cohort: implications for clinical and epidemiological studies.

01-05-2023

Journal of lipid research

Role of enterocyte Enpp2 and autotaxin in regulating lipopolysaccharide levels, systemic inflammation, and atherosclerosis.

01-05-2023

Molecular cancer research : MCR

The Elongin BC Complex Negatively Regulates AXL and Marks a Differentiated Phenotype in Melanoma.

01-05-2023

Angiogenesis

Proinflammatory activity of VEGF-targeted treatment through reversal of tumor endothelial cell anergy.

01-05-2023

Journal of controlled release : official journal of the Controlled Release Society

Radiosensitisation by olaparib through focused ultrasound delivery in a diffuse midline glioma model.

01-05-2023

The Journal of experimental medicine

IFN-γ signature enables selection of neoadjuvant treatment in patients with stage III melanoma.

01-05-2023

Nature reviews. Clinical oncology

Functional precision oncology using patient-derived assays: bridging genotype and phenotype.

01-05-2023

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Dosimetric benefit of a library of plans versus single-plan strategy for pre-operative gastric cancer radiotherapy.

01-05-2023

Cancer

Reply to "Can we avoid thoracic radiotherapy in young females with Hodgkin lymphoma?".

01-05-2023

European journal of human genetics : EJHG

FANCM missense variants and breast cancer risk: a case-control association study of 75,156 European women.

01-05-2023

Haematologica

Combination therapy with crizotinib and vinblastine for relapsed or refractory pediatric ALK-positive anaplastic large cell lymphoma.

01-05-2023

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Pregnancy-associated desmoid fibromatosis: A Dutch multi-centre retrospective study.

01-05-2023

Nature cancer

CD103⁺ regulatory T cells underlie resistance to radio-immunotherapy and impair CD8⁺ T cell activation in glioblastoma.

01-05-2023

Cancer

Impaired social functioning in adolescent and young adult sarcoma survivors: Prevalence and risk factors.

01-05-2023

Heliyon

A validated HPLC-MS/MS method for simultaneously analyzing curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetra-hydrocurcumin and piperine in human plasma, urine or feces.

01-05-2023

JTO clinical and research reports

Self-Reported Cognitive Function and Quality of Life in Patients With SCLC in the Hippocampal Avoidance Prophylactic Cranial Irradiation Versus Prophylactic Cranial Irradiation Randomized Phase 3 Trial (NCT01780675).

01-05-2023

European radiology

Artificial intelligence-based diagnosis of asbestosis: analysis of a database with applicants for asbestosis state aid.

01-05-2023

European journal of cancer (Oxford, England : 1990)

Surgical outcomes of lymph node dissections for stage III melanoma after neoadjuvant systemic therapy are not inferior to upfront surgery.

01-05-2023

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Radiotherapy dosimetry at multiple levels to improve precision, development and understanding of treatment.

01-05-2023

BMC bioinformatics

ecpc: an R-package for generic co-data models for high-dimensional prediction.

26-04-2023

bioRxiv : the preprint server for biology

Competition between transcription and loop extrusion modulates promoter and enhancer dynamics.

26-04-2023

International journal of molecular sciences

Identification of Protein Complexes by Integrating Protein Abundance and Interaction Features Using a Deep Learning Strategy.

26-04-2023

Cell reports

Drug-repurposing screen on patient-derived organoids identifies therapy-induced vulnerability in KRAS-mutant colon cancer.

25-04-2023

Oncoimmunology

Neoadjuvant immune checkpoint blockade triggers persistent and systemic T_reg activation which blunts therapeutic efficacy against metastatic spread of breast tumors.

24-04-2023

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

PERSPECTIVEs on supervised exercise programs in people with metastatic breast cancer- a qualitative study in four European countries.

19-04-2023

A Survival Tree of Advanced Melanoma Patients with Brain Metastases Treated with Immune Checkpoint Inhibitors.

Psychological and social challenges of patients with locally advanced and metastatic gastrointestinal stromal tumours (GIST) on long-term treatment with tyrosine kinase inhibitors: a qualitative study with patients and medical oncologists.

DNA supercoiling restricts the transcriptional bursting of neighboring eukaryotic genes.

Microcamera Visualisation System to Overcome Specular Reflections for Tissue Imaging.

Oncological surgery follow-up and quality of life: meta-analysis.

The Trial within Cohorts (TwiCs) study design in oncology: experience and methodological reflections.

Immune landscape of breast tumors with low and intermediate estrogen receptor expression.

PREDICT validity for prognosis of breast cancer patients with pathogenic BRCA1/2 variants.

Optimization of a Quantitative Anti-Drug Antibodies against Infliximab Assay with the Liquid Chromatography-Tandem Mass Spectrometry: A Method Validation Study and Future Perspectives.

High-Grade Serous Carcinoma at Risk-Reducing Salpingo-Oophorectomy in Asymptomatic Carriers of BRCA1/2 Pathogenic Variants: Prevalence and Clinical Factors.

Tissue Classification of Breast Cancer by Hyperspectral Unmixing.

Breast cancer genomes from CHEK2 c.1100delC mutation carriers lack somatic TP53 mutations and display a unique structural variant size distribution profile.

A living biobank of patient-derived ductal carcinoma in situ mouse-intraductal xenografts identifies risk factors for invasive progression.

Systematic screening identifies ABCG2 as critical factor underlying synergy of kinase inhibitors with transcriptional CDK inhibitors.

PRC2.1- and PRC2.2-specific accessory proteins drive recruitment of different forms of canonical PRC1.

Multidimensional Imaging of Breast Cancer.

A deep learning-based application for COVID-19 diagnosis on CT: The Imaging COVID-19 AI initiative.

Drug-drug synthetic lethality to combat cancer: From bench to bedside.

Dynamic epistasis analysis reveals how chromatin remodeling regulates transcriptional bursting.

Definition, diagnosis and treatment of oligometastatic oesophagogastric cancer: A Delphi consensus study in Europe.

Influence of germline variations in drug transporters ABCB1 and ABCG2 on intracerebral osimertinib efficacy in patients with non-small cell lung cancer.

Exposure-Response Analyses of Olaparib in Real-Life Patients with Ovarian Cancer.

Enhancement of the Oral Availability of Cabazitaxel Using the Cytochrome P450 3A (CYP3A) Inhibitor Ritonavir in Mice.

Clinical evaluation of late outcomes in Dutch childhood cancer survivors: Methodology of the DCCSS LATER 2 study.

Spontaneous early-onset neurodegeneration in the brainstem and spinal cord of NSG, NOG, and NXG mice.

Pathology review identifies frequent misdiagnoses in recurrent classic Hodgkin lymphoma in a nationwide cohort: implications for clinical and epidemiological studies.

Role of enterocyte Enpp2 and autotaxin in regulating lipopolysaccharide levels, systemic inflammation, and atherosclerosis.

The Elongin BC Complex Negatively Regulates AXL and Marks a Differentiated Phenotype in Melanoma.

Proinflammatory activity of VEGF-targeted treatment through reversal of tumor endothelial cell anergy.

Radiosensitisation by olaparib through focused ultrasound delivery in a diffuse midline glioma model.

IFN-γ signature enables selection of neoadjuvant treatment in patients with stage III melanoma.

Functional precision oncology using patient-derived assays: bridging genotype and phenotype.

Dosimetric benefit of a library of plans versus single-plan strategy for pre-operative gastric cancer radiotherapy.

Reply to "Can we avoid thoracic radiotherapy in young females with Hodgkin lymphoma?".

FANCM missense variants and breast cancer risk: a case-control association study of 75,156 European women.

Combination therapy with crizotinib and vinblastine for relapsed or refractory pediatric ALK-positive anaplastic large cell lymphoma.

Pregnancy-associated desmoid fibromatosis: A Dutch multi-centre retrospective study.

CD103+ regulatory T cells underlie resistance to radio-immunotherapy and impair CD8+ T cell activation in glioblastoma.

Impaired social functioning in adolescent and young adult sarcoma survivors: Prevalence and risk factors.

A validated HPLC-MS/MS method for simultaneously analyzing curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetra-hydrocurcumin and piperine in human plasma, urine or feces.

Self-Reported Cognitive Function and Quality of Life in Patients With SCLC in the Hippocampal Avoidance Prophylactic Cranial Irradiation Versus Prophylactic Cranial Irradiation Randomized Phase 3 Trial (NCT01780675).

Artificial intelligence-based diagnosis of asbestosis: analysis of a database with applicants for asbestosis state aid.

Surgical outcomes of lymph node dissections for stage III melanoma after neoadjuvant systemic therapy are not inferior to upfront surgery.

Radiotherapy dosimetry at multiple levels to improve precision, development and understanding of treatment.

ecpc: an R-package for generic co-data models for high-dimensional prediction.

Competition between transcription and loop extrusion modulates promoter and enhancer dynamics.

Identification of Protein Complexes by Integrating Protein Abundance and Interaction Features Using a Deep Learning Strategy.

Drug-repurposing screen on patient-derived organoids identifies therapy-induced vulnerability in KRAS-mutant colon cancer.

Neoadjuvant immune checkpoint blockade triggers persistent and systemic Treg activation which blunts therapeutic efficacy against metastatic spread of breast tumors.

PERSPECTIVEs on supervised exercise programs in people with metastatic breast cancer- a qualitative study in four European countries.

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CD103⁺ regulatory T cells underlie resistance to radio-immunotherapy and impair CD8⁺ T cell activation in glioblastoma.

Neoadjuvant immune checkpoint blockade triggers persistent and systemic T_reg activation which blunts therapeutic efficacy against metastatic spread of breast tumors.