Publications

Nucleic acids research

Transcription factor clusters enable target search but do not contribute to target gene activation.

23-06-2023

Nucleic acids research

Defining the fine structure of promoter activity on a genome-wide scale with CISSECTOR.

23-06-2023

Cancers

Spectrum and Frequency of Germline FANCM Protein-Truncating Variants in 44,803 European Female Breast Cancer Cases.

23-06-2023

Human reproduction open

Cancer risk in children, adolescents, and young adults conceived by ART in 1983-2011.

22-06-2023

Breast cancer research : BCR

Associations of height, body mass index, and weight gain with breast cancer risk in carriers of a pathogenic variant in BRCA1 or BRCA2: the BRCA1 and BRCA2 Cohort Consortium.

20-06-2023

medRxiv : the preprint server for health sciences

Understanding the genetic complexity of puberty timing across the allele frequency spectrum.

20-06-2023

Cancers

Caring for Adolescents and Young Adults (AYA) with Cancer: A Scoping Review into Caregiver Burdens and Needs.

20-06-2023

Breast cancer research : BCR

BluePrint molecular subtypes predict response to neoadjuvant pertuzumab in HER2-positive breast cancer.

19-06-2023

STAR protocols

Protocol for ex vivo culture of patient-derived tumor fragments.

16-06-2023

EJNMMI research

Predicting the effect of different folate doses on [⁶⁸Ga]Ga-PSMA-11 organ and tumor uptake using physiologically based pharmacokinetic modeling.

15-06-2023

International journal of cancer

Time interval from primary melanoma to first distant recurrence in relation to patient outcomes in advanced melanoma.

15-06-2023

BMJ open

Towards Response ADAptive Radiotherapy for organ preservation for intermediate-risk rectal cancer (preRADAR): protocol of a phase I dose-escalation trial.

15-06-2023

Cancer cell

Taxanes trigger cancer cell killing in vivo by inducing non-canonical T cell cytotoxicity.

12-06-2023

Journal of visualized experiments : JoVE

Laser Ablation and Intravital Microscopy to Study Intestinal Remodeling.

09-06-2023

Nature communications

THRONCAT: metabolic labeling of newly synthesized proteins using a bioorthogonal threonine analog.

08-06-2023

Scientific reports

Microcalcification crystallography as a potential marker of DCIS recurrence.

08-06-2023

Cancers

Radiogenomics Analysis Linking Multiparametric MRI and Transcriptomics in Prostate Cancer.

06-06-2023

Biomolecules

A Truncated 14-Amino-Acid Myelin Protein-Zero-Targeting Peptide for Fluorescence-Guided Nerve-Preserving Surgery.

05-06-2023

EMBO reports

DOT1L regulates chromatin reorganization and gene expression during sperm differentiation.

05-06-2023

BMC cancer

ABPEPserver: a web application for documentation and analysis of substitutants.

03-06-2023

Science advances

FIRRM/C1orf112 mediates resolution of homologous recombination intermediates in response to DNA interstrand crosslinks.

02-06-2023

The oncologist

Efficacy of T-Cell Receptor-Based Adoptive Cell Therapy in Cutaneous Melanoma: A Meta-Analysis.

02-06-2023

Molecular & cellular proteomics : MCP

Ubiquitinome Profiling Reveals in Vivo UBE2D3 Targets and Implicates UBE2D3 in Protein Quality Control.

01-06-2023

Journal of cancer survivorship : research and practice

Association between peripheral neuropathy and sleep quality among colorectal cancer patients from diagnosis until 2-year follow-up: results from the PROFILES registry.

01-06-2023

European radiology

Is the generalizability of a developed artificial intelligence algorithm for COVID-19 on chest CT sufficient for clinical use? Results from the International Consortium for COVID-19 Imaging AI (ICOVAI).

01-06-2023

Nature biotechnology

Identification of patient-specific CD4⁺ and CD8⁺ T cell neoantigens through HLA-unbiased genetic screens.

01-06-2023

European journal of cancer (Oxford, England : 1990)

Response to checkpoint inhibition and targeted therapy in melanoma patients with concurrent haematological malignancies.

01-06-2023

Cancer immunology, immunotherapy : CII

The common HLA class I-restricted tumor-infiltrating T cell response in HPV16-induced cancer.

01-06-2023

Current treatment options in oncology

Immunotherapy for Metastatic Triple Negative Breast Cancer: Current Paradigm and Future Approaches.

01-06-2023

Molecular oncology

Molecular Oncology and the EACR: new partners in communicating and supporting cancer research.

01-06-2023

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

A systematic review of validated assessments methods for head and neck lymphedema.

01-06-2023

Annals of surgical oncology

Surgical Oncologists and Nurses in Breast Cancer Care are Ready to Provide Pre-Test Genetic Counseling.

01-06-2023

Molecular oncology

Rational combination of SHP2 and mTOR inhibition for the treatment of hepatocellular carcinoma.

01-06-2023

Journal of the National Cancer Center

Quality assurance and safety of hippocampal avoidance prophylactic cranial irradiation in the multicenter randomized phase III trial (NCT01780675).

01-06-2023

Cancer medicine

Physical symptom burden in patients with desmoid-type fibromatosis and its impact on health-related quality of life and healthcare use.

01-06-2023

Cancer medicine

Learning from long-term adolescent and young adult (AYA) cancer survivors regarding their age-specific care needs to improve current AYA care programs.

01-06-2023

European urology

Corrigendum to "Assessment of Predictive Genomic Biomarkers for Response to Cisplatin-based Neoadjuvant Chemotherapy in Bladder Cancer" [Eur Urol 2023;83:313-17].

01-06-2023

Annals of surgery

Health-related Quality of Life of Patients With Non-Intra-abdominal Desmoid-Type Fibromatosis During Active Surveillance: Results of a Prospective Observational Study.

01-06-2023

ESMO open

Extended follow-up from JAVELIN Renal 101: subgroup analysis of avelumab plus axitinib versus sunitinib by the International Metastatic Renal Cell Carcinoma Database Consortium risk group in patients with advanced renal cell carcinoma.

01-06-2023

Frontiers in immunology

Volume imaging to interrogate cancer cell-tumor microenvironment interactions in space and time.

01-06-2023

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

The inhibitory and inducing effects of ritonavir on hepatic and intestinal CYP3A and other drug-handling proteins.

01-06-2023

Molecular oncology

Engaging European society at the forefront of cancer research and care: How discussions at the 5^th Gago Conference on European Science policy led to the Heidelberg Manifesto.

01-06-2023

European urology

European Association of Urology-American Society of Clinical Oncology Collaborative Guideline on Penile Cancer: 2023 Update.

01-06-2023

European journal of immunology

Acidity-mediated induction of FoxP3⁺ regulatory T cells.

01-06-2023

Cancer chemotherapy and pharmacology

Exposure-response analyses of BRAF- and MEK-inhibitors dabrafenib plus trametinib in melanoma patients.

01-06-2023

Cancer medicine

Phase II study (KAMELEON) of single-agent T-DM1 in patients with HER2-positive advanced urothelial bladder cancer or pancreatic cancer/cholangiocarcinoma.

01-06-2023

Nature medicine

Neoadjuvant immunotherapy for melanoma is now ready for clinical practice.

01-06-2023

Nature structural & molecular biology

Structural basis of centromeric cohesion protection.

01-06-2023

Journal of neuro-oncology

Optimizing treatment of brain metastases in an era of novel systemic treatments: a single center consecutive series.

01-06-2023

Journal of immunotherapy (Hagerstown, Md. : 1997)

Real-world Outcomes of Ipilimumab Plus Nivolumab Combination Therapy in a Nation-wide Cohort of Advanced Melanoma Patients in the Netherlands.

01-06-2023

Transcription factor clusters enable target search but do not contribute to target gene activation.

Defining the fine structure of promoter activity on a genome-wide scale with CISSECTOR.

Spectrum and Frequency of Germline FANCM Protein-Truncating Variants in 44,803 European Female Breast Cancer Cases.

Cancer risk in children, adolescents, and young adults conceived by ART in 1983-2011.

Associations of height, body mass index, and weight gain with breast cancer risk in carriers of a pathogenic variant in BRCA1 or BRCA2: the BRCA1 and BRCA2 Cohort Consortium.

Understanding the genetic complexity of puberty timing across the allele frequency spectrum.

Caring for Adolescents and Young Adults (AYA) with Cancer: A Scoping Review into Caregiver Burdens and Needs.

BluePrint molecular subtypes predict response to neoadjuvant pertuzumab in HER2-positive breast cancer.

Protocol for ex vivo culture of patient-derived tumor fragments.

Predicting the effect of different folate doses on [68Ga]Ga-PSMA-11 organ and tumor uptake using physiologically based pharmacokinetic modeling.

Time interval from primary melanoma to first distant recurrence in relation to patient outcomes in advanced melanoma.

Towards Response ADAptive Radiotherapy for organ preservation for intermediate-risk rectal cancer (preRADAR): protocol of a phase I dose-escalation trial.

Taxanes trigger cancer cell killing in vivo by inducing non-canonical T cell cytotoxicity.

Laser Ablation and Intravital Microscopy to Study Intestinal Remodeling.

THRONCAT: metabolic labeling of newly synthesized proteins using a bioorthogonal threonine analog.

Microcalcification crystallography as a potential marker of DCIS recurrence.

Radiogenomics Analysis Linking Multiparametric MRI and Transcriptomics in Prostate Cancer.

A Truncated 14-Amino-Acid Myelin Protein-Zero-Targeting Peptide for Fluorescence-Guided Nerve-Preserving Surgery.

DOT1L regulates chromatin reorganization and gene expression during sperm differentiation.

ABPEPserver: a web application for documentation and analysis of substitutants.

FIRRM/C1orf112 mediates resolution of homologous recombination intermediates in response to DNA interstrand crosslinks.

Efficacy of T-Cell Receptor-Based Adoptive Cell Therapy in Cutaneous Melanoma: A Meta-Analysis.

Ubiquitinome Profiling Reveals in Vivo UBE2D3 Targets and Implicates UBE2D3 in Protein Quality Control.

Association between peripheral neuropathy and sleep quality among colorectal cancer patients from diagnosis until 2-year follow-up: results from the PROFILES registry.

Is the generalizability of a developed artificial intelligence algorithm for COVID-19 on chest CT sufficient for clinical use? Results from the International Consortium for COVID-19 Imaging AI (ICOVAI).

Identification of patient-specific CD4+ and CD8+ T cell neoantigens through HLA-unbiased genetic screens.

Response to checkpoint inhibition and targeted therapy in melanoma patients with concurrent haematological malignancies.

The common HLA class I-restricted tumor-infiltrating T cell response in HPV16-induced cancer.

Immunotherapy for Metastatic Triple Negative Breast Cancer: Current Paradigm and Future Approaches.

Molecular Oncology and the EACR: new partners in communicating and supporting cancer research.

A systematic review of validated assessments methods for head and neck lymphedema.

Surgical Oncologists and Nurses in Breast Cancer Care are Ready to Provide Pre-Test Genetic Counseling.

Rational combination of SHP2 and mTOR inhibition for the treatment of hepatocellular carcinoma.

Quality assurance and safety of hippocampal avoidance prophylactic cranial irradiation in the multicenter randomized phase III trial (NCT01780675).

Physical symptom burden in patients with desmoid-type fibromatosis and its impact on health-related quality of life and healthcare use.

Learning from long-term adolescent and young adult (AYA) cancer survivors regarding their age-specific care needs to improve current AYA care programs.

Corrigendum to "Assessment of Predictive Genomic Biomarkers for Response to Cisplatin-based Neoadjuvant Chemotherapy in Bladder Cancer" [Eur Urol 2023;83:313-17].

Health-related Quality of Life of Patients With Non-Intra-abdominal Desmoid-Type Fibromatosis During Active Surveillance: Results of a Prospective Observational Study.

Extended follow-up from JAVELIN Renal 101: subgroup analysis of avelumab plus axitinib versus sunitinib by the International Metastatic Renal Cell Carcinoma Database Consortium risk group in patients with advanced renal cell carcinoma.

Volume imaging to interrogate cancer cell-tumor microenvironment interactions in space and time.

The inhibitory and inducing effects of ritonavir on hepatic and intestinal CYP3A and other drug-handling proteins.

Engaging European society at the forefront of cancer research and care: How discussions at the 5th Gago Conference on European Science policy led to the Heidelberg Manifesto.

European Association of Urology-American Society of Clinical Oncology Collaborative Guideline on Penile Cancer: 2023 Update.

Acidity-mediated induction of FoxP3+ regulatory T cells.

Exposure-response analyses of BRAF- and MEK-inhibitors dabrafenib plus trametinib in melanoma patients.

Phase II study (KAMELEON) of single-agent T-DM1 in patients with HER2-positive advanced urothelial bladder cancer or pancreatic cancer/cholangiocarcinoma.

Neoadjuvant immunotherapy for melanoma is now ready for clinical practice.

Structural basis of centromeric cohesion protection.

Optimizing treatment of brain metastases in an era of novel systemic treatments: a single center consecutive series.

Real-world Outcomes of Ipilimumab Plus Nivolumab Combination Therapy in a Nation-wide Cohort of Advanced Melanoma Patients in the Netherlands.

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Predicting the effect of different folate doses on [⁶⁸Ga]Ga-PSMA-11 organ and tumor uptake using physiologically based pharmacokinetic modeling.

Identification of patient-specific CD4⁺ and CD8⁺ T cell neoantigens through HLA-unbiased genetic screens.

Engaging European society at the forefront of cancer research and care: How discussions at the 5^th Gago Conference on European Science policy led to the Heidelberg Manifesto.

Acidity-mediated induction of FoxP3⁺ regulatory T cells.