Publications

Pharmaceuticals (Basel, Switzerland)

P-Glycoprotein (MDR1/ABCB1) Restricts Brain Accumulation of the Novel EGFR Inhibitor EAI045 and Oral Elacridar Coadministration Enhances Its Brain Accumulation and Oral Exposure.

08-09-2022

Nature communications

MAD2L2 promotes replication fork protection and recovery in a shieldin-independent and REV3L-dependent manner.

08-09-2022

PloS one

Indisulam synergizes with palbociclib to induce senescence through inhibition of CDK2 kinase activity.

07-09-2022

EMBO molecular medicine

A type IV Autotaxin inhibitor ameliorates acute liver injury and nonalcoholic steatohepatitis.

07-09-2022

Journal of translational medicine

Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 2nd - 4th, 2021, Italy).

04-09-2022

Cancer discovery

Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence.

02-09-2022

The oncologist

A Single-arm Phase II Study Combining NLG207, a Nanoparticle Camptothecin, with Enzalutamide in Advanced Metastatic Castration-resistant Prostate Cancer Post-Enzalutamide.

02-09-2022

European journal of cancer (Oxford, England : 1990)

Incorporating progesterone receptor expression into the PREDICT breast prognostic model.

01-09-2022

Nature genetics

Genetic determinants of chromatin reveal prostate cancer risk mediated by context-dependent gene regulation.

01-09-2022

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Feasibility of therapeutic drug monitoring of sorafenib in patients with liver or thyroid cancer.

01-09-2022

Life science alliance

Genetic and compound screens uncover factors modulating cancer cell response to indisulam.

01-09-2022

IUCrData

Crystal structure of the second extracellular domain of human tetraspanin CD9: twinning and diffuse scattering.

01-09-2022

Seminars in cancer biology

Biology-guided precision medicine in rare cancers: Lessons from sarcomas and neuroendocrine tumours.

01-09-2022

Genome biology

CTCF and cohesin promote focal detachment of DNA from the nuclear lamina.

01-09-2022

Seminars in nuclear medicine

Application of Deep Learning in Breast Cancer Imaging.

01-09-2022

Nature cancer

Keeping track of the T cells that matter.

01-09-2022

Inflammatory bowel diseases

Genetic Profiling of Colorectal Carcinomas of Patients with Primary Sclerosing Cholangitis and Inflammatory Bowel Disease.

01-09-2022

Chromosoma

Life of double minutes: generation, maintenance, and elimination.

01-09-2022

Neuro-oncology

Glioblastoma scRNA-seq shows treatment-induced, immune-dependent increase in mesenchymal cancer cells and structural variants in distal neural stem cells.

01-09-2022

JCO precision oncology

BRAF and NRAS Mutation Status and Response to Checkpoint Inhibition in Advanced Melanoma.

01-09-2022

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

"Who needs a mean dose if you can FLAME?".

01-09-2022

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)

Largest diameter delineations can substitute 3D tumor volume delineations for radiomics prediction of human papillomavirus status on MRI's of oropharyngeal cancer.

01-09-2022

Nature

Author Correction: PHGDH heterogeneity potentiates cancer cell dissemination and metastasis.

01-09-2022

Immuno-oncology technology

Effective generation of tumor-infiltrating lymphocyte products from metastatic non-small-cell lung cancer (NSCLC) lesions irrespective of location and previous treatments.

01-09-2022

The Lancet. Oncology

De-escalation of radiotherapy after primary chemotherapy in cT1-2N1 breast cancer (RAPCHEM; BOOG 2010-03): 5-year follow-up results of a Dutch, prospective, registry study.

01-09-2022

Clinical and translational radiation oncology

Exposure of the heart and cardiac valves in women irradiated for breast cancer 1970-2009.

01-09-2022

European journal of cancer (Oxford, England : 1990)

Microsatellite instability and sex differences in resectable gastric cancer - A pooled analysis of three European cohorts.

01-09-2022

Psycho-oncology

Dyadic coping and its association with emotional functioning in couples confronted with advanced cancer: Results of the multicenter observational eQuiPe study.

01-09-2022

Annals of oncology : official journal of the European Society for Medical Oncology

Single-agent anti-PD-1 or combined with ipilimumab in patients with mucosal melanoma: an international, retrospective, cohort study.

01-09-2022

Pediatric blood & cancer

Clinical trials in desmoid-type fibromatosis in children and adults: A systematic review.

01-09-2022

The EMBO journal

ZAKβ is activated by cellular compression and mediates contraction-induced MAP kinase signaling in skeletal muscle.

01-09-2022

Immuno-oncology technology

MART-1 TCR gene-modified peripheral blood T cells for the treatment of metastatic melanoma: a phase I/IIa clinical trial.

01-09-2022

Nature

Publisher Correction: Truncated FGFR2 is a clinically actionable oncogene in multiple cancers.

01-09-2022

Key Publication

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Identifying health-related quality of life cut-off scores that indicate the need for supportive care in young adults with cancer.

01-09-2022

Journal of structural biology

Mitoxantrone stacking does not define the active or inactive state of USP15 catalytic domain.

01-09-2022

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Daily Oral Ibandronate With Adjuvant Endocrine Therapy in Postmenopausal Women With Estrogen Receptor-Positive Breast Cancer (BOOG 2006-04): Randomized Phase III TEAM-IIB Trial.

01-09-2022

European urology

Patterns of Failure Following External Beam Radiotherapy With or Without an Additional Focal Boost in the Randomized Controlled FLAME Trial for Localized Prostate Cancer.

01-09-2022

Abdominal radiology (New York)

Percutaneous cryoablation: a novel treatment option in non-visceral metastases of the abdominal cavity after prior surgery.

01-09-2022

European journal of haematology

Cell-free DNA levels are increased in acute graft-versus-host disease.

01-09-2022

Journal for immunotherapy of cancer

Preclinical characterization and clinical translation of pharmacodynamic markers for MK-5890: a human CD27 activating antibody for cancer immunotherapy.

01-09-2022

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Evaluation of an individual feedback report on patient-reported outcomes in the Prospective Dutch ColoRectal Cancer cohort.

01-09-2022

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Exploring supportive care and information needs through a proposed eHealth application among melanoma patients undergoing systemic therapy: a qualitative study.

01-09-2022

International journal of molecular sciences

The Mechanism-Based Inactivation of CYP3A4 by Ritonavir: What Mechanism?

30-08-2022

The Plant cell

The host exocyst complex is targeted by a conserved bacterial type-III effector that promotes virulence.

25-08-2022

Cell discovery

EGFR blockade confers sensitivity to cabozantinib in hepatocellular carcinoma.

23-08-2022

Cancers

ADC Values of Cytologically Benign and Cytologically Malignant 18 F-FDG PET-Positive Lymph Nodes of Head and Neck Squamous Cell Carcinoma.

20-08-2022

iScience

Identifying mutant-specific multi-drug combinations using comparative network reconstruction.

19-08-2022

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Development and validation of a high-performance liquid chromatography tandem mass spectrometry method for the quantification of the antiparasitic and antifungal drug amphotericin B in human skin tissue.

15-08-2022

Science immunology

Signatures of recent activation identify a circulating T cell compartment containing tumor-specific antigen receptors with high avidity.

12-08-2022

Nucleic acids research

HDAC1 and PRC2 mediate combinatorial control in SPI1/PU.1-dependent gene repression in murine erythroleukaemia.

12-08-2022

P-Glycoprotein (MDR1/ABCB1) Restricts Brain Accumulation of the Novel EGFR Inhibitor EAI045 and Oral Elacridar Coadministration Enhances Its Brain Accumulation and Oral Exposure.

MAD2L2 promotes replication fork protection and recovery in a shieldin-independent and REV3L-dependent manner.

Indisulam synergizes with palbociclib to induce senescence through inhibition of CDK2 kinase activity.

A type IV Autotaxin inhibitor ameliorates acute liver injury and nonalcoholic steatohepatitis.

Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 2nd - 4th, 2021, Italy).

Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence.

A Single-arm Phase II Study Combining NLG207, a Nanoparticle Camptothecin, with Enzalutamide in Advanced Metastatic Castration-resistant Prostate Cancer Post-Enzalutamide.

Incorporating progesterone receptor expression into the PREDICT breast prognostic model.

Genetic determinants of chromatin reveal prostate cancer risk mediated by context-dependent gene regulation.

Feasibility of therapeutic drug monitoring of sorafenib in patients with liver or thyroid cancer.

Genetic and compound screens uncover factors modulating cancer cell response to indisulam.

Crystal structure of the second extracellular domain of human tetraspanin CD9: twinning and diffuse scattering.

Biology-guided precision medicine in rare cancers: Lessons from sarcomas and neuroendocrine tumours.

CTCF and cohesin promote focal detachment of DNA from the nuclear lamina.

Application of Deep Learning in Breast Cancer Imaging.

Keeping track of the T cells that matter.

Genetic Profiling of Colorectal Carcinomas of Patients with Primary Sclerosing Cholangitis and Inflammatory Bowel Disease.

Life of double minutes: generation, maintenance, and elimination.

Glioblastoma scRNA-seq shows treatment-induced, immune-dependent increase in mesenchymal cancer cells and structural variants in distal neural stem cells.

BRAF and NRAS Mutation Status and Response to Checkpoint Inhibition in Advanced Melanoma.

"Who needs a mean dose if you can FLAME?".

Largest diameter delineations can substitute 3D tumor volume delineations for radiomics prediction of human papillomavirus status on MRI's of oropharyngeal cancer.

Author Correction: PHGDH heterogeneity potentiates cancer cell dissemination and metastasis.

Effective generation of tumor-infiltrating lymphocyte products from metastatic non-small-cell lung cancer (NSCLC) lesions irrespective of location and previous treatments.

De-escalation of radiotherapy after primary chemotherapy in cT1-2N1 breast cancer (RAPCHEM; BOOG 2010-03): 5-year follow-up results of a Dutch, prospective, registry study.

Exposure of the heart and cardiac valves in women irradiated for breast cancer 1970-2009.

Microsatellite instability and sex differences in resectable gastric cancer - A pooled analysis of three European cohorts.

Dyadic coping and its association with emotional functioning in couples confronted with advanced cancer: Results of the multicenter observational eQuiPe study.

Single-agent anti-PD-1 or combined with ipilimumab in patients with mucosal melanoma: an international, retrospective, cohort study.

Clinical trials in desmoid-type fibromatosis in children and adults: A systematic review.

ZAKβ is activated by cellular compression and mediates contraction-induced MAP kinase signaling in skeletal muscle.

MART-1 TCR gene-modified peripheral blood T cells for the treatment of metastatic melanoma: a phase I/IIa clinical trial.

Publisher Correction: Truncated FGFR2 is a clinically actionable oncogene in multiple cancers.

Identifying health-related quality of life cut-off scores that indicate the need for supportive care in young adults with cancer.

Mitoxantrone stacking does not define the active or inactive state of USP15 catalytic domain.

Daily Oral Ibandronate With Adjuvant Endocrine Therapy in Postmenopausal Women With Estrogen Receptor-Positive Breast Cancer (BOOG 2006-04): Randomized Phase III TEAM-IIB Trial.

Patterns of Failure Following External Beam Radiotherapy With or Without an Additional Focal Boost in the Randomized Controlled FLAME Trial for Localized Prostate Cancer.

Percutaneous cryoablation: a novel treatment option in non-visceral metastases of the abdominal cavity after prior surgery.

Cell-free DNA levels are increased in acute graft-versus-host disease.

Preclinical characterization and clinical translation of pharmacodynamic markers for MK-5890: a human CD27 activating antibody for cancer immunotherapy.

Evaluation of an individual feedback report on patient-reported outcomes in the Prospective Dutch ColoRectal Cancer cohort.

Exploring supportive care and information needs through a proposed eHealth application among melanoma patients undergoing systemic therapy: a qualitative study.

The Mechanism-Based Inactivation of CYP3A4 by Ritonavir: What Mechanism?

The host exocyst complex is targeted by a conserved bacterial type-III effector that promotes virulence.

EGFR blockade confers sensitivity to cabozantinib in hepatocellular carcinoma.

ADC Values of Cytologically Benign and Cytologically Malignant 18 F-FDG PET-Positive Lymph Nodes of Head and Neck Squamous Cell Carcinoma.

Identifying mutant-specific multi-drug combinations using comparative network reconstruction.

Development and validation of a high-performance liquid chromatography tandem mass spectrometry method for the quantification of the antiparasitic and antifungal drug amphotericin B in human skin tissue.

Signatures of recent activation identify a circulating T cell compartment containing tumor-specific antigen receptors with high avidity.

HDAC1 and PRC2 mediate combinatorial control in SPI1/PU.1-dependent gene repression in murine erythroleukaemia.

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