Publications

Molecular cancer research : MCR

Interleukin-1R-associated kinase 2 is a novel modulator of the transforming growth factor beta signaling cascade.

01-04-2010

Clinical cancer research : an official journal of the American Association for Cancer Research

Candidate biomarkers of response to an experimental cancer drug identified through a large-scale RNA interference genetic screen.

15-09-2009

Cancer cell

ZNF423 is critically required for retinoic acid-induced differentiation and is a marker of neuroblastoma outcome.

07-04-2009

PloS one

A large scale shRNA barcode screen identifies the circadian clock component ARNTL as putative regulator of the p53 tumor suppressor pathway.

12-03-2009

Nature

Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1.

29-11-2007

Cancer cell

A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer.

01-10-2007

The Journal of biological chemistry

Telomerase-independent regulation of ATR by human telomerase RNA.

29-12-2006

Nature methods

shRNA libraries and their use in cancer genetics.

01-09-2006

Nature chemical biology

An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors.

01-04-2006

Cold Spring Harbor symposia on quantitative biology

Functional identification of cancer-relevant genes through large-scale RNA interference screens in mammalian cells.

25-08-2005

Cell

A genetic screen identifies PITX1 as a suppressor of RAS activity and tumorigenicity.

17-06-2005

Nature

A large-scale RNAi screen in human cells identifies new components of the p53 pathway.

25-03-2004

Genes & development

Degradation of E2F by the ubiquitin-proteasome pathway: regulation by retinoblastoma family proteins and adenovirus transforming proteins.

01-12-1996

Biochimica et biophysica acta

Cell cycle regulation by the retinoblastoma family of growth inhibitory proteins.

07-06-1996

The Journal of biological chemistry

Functional analysis of Burkitt's lymphoma mutant c-Myc proteins.

08-03-1996

Genes & development

Regulation of the retinoblastoma protein-related p107 by G1 cyclin complexes.

01-06-1995

Molecular and cellular biology

E2F-5, a new E2F family member that interacts with p130 in vivo.

01-06-1995

Genes & development

E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo.

15-11-1994

The EMBO journal

Interaction of c-Myc with the pRb-related protein p107 results in inhibition of c-Myc-mediated transactivation.

01-09-1994

The Journal of biological chemistry

Cell-cell adhesion mediated by a receptor-like protein tyrosine phosphatase.

05-08-1993

FEBS letters

Cloning, expression and chromosomal localization of a new putative receptor-like protein tyrosine phosphatase.

23-09-1991

Interleukin-1R-associated kinase 2 is a novel modulator of the transforming growth factor beta signaling cascade.

Candidate biomarkers of response to an experimental cancer drug identified through a large-scale RNA interference genetic screen.

ZNF423 is critically required for retinoic acid-induced differentiation and is a marker of neuroblastoma outcome.

A large scale shRNA barcode screen identifies the circadian clock component ARNTL as putative regulator of the p53 tumor suppressor pathway.

Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1.

A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer.

Telomerase-independent regulation of ATR by human telomerase RNA.

shRNA libraries and their use in cancer genetics.

An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors.

Functional identification of cancer-relevant genes through large-scale RNA interference screens in mammalian cells.

A genetic screen identifies PITX1 as a suppressor of RAS activity and tumorigenicity.

A large-scale RNAi screen in human cells identifies new components of the p53 pathway.

Degradation of E2F by the ubiquitin-proteasome pathway: regulation by retinoblastoma family proteins and adenovirus transforming proteins.

Cell cycle regulation by the retinoblastoma family of growth inhibitory proteins.

Functional analysis of Burkitt's lymphoma mutant c-Myc proteins.

Regulation of the retinoblastoma protein-related p107 by G1 cyclin complexes.

E2F-5, a new E2F family member that interacts with p130 in vivo.

E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo.

Interaction of c-Myc with the pRb-related protein p107 results in inhibition of c-Myc-mediated transactivation.

Cell-cell adhesion mediated by a receptor-like protein tyrosine phosphatase.

Cloning, expression and chromosomal localization of a new putative receptor-like protein tyrosine phosphatase.

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