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Results found: 118

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PloS one

A large scale shRNA barcode screen identifies the circadian clock component ARNTL as putative regulator of the p53 tumor suppressor pathway.

12-03-2009

Nature

Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1.

29-11-2007

Cancer cell

A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer.

01-10-2007

The Journal of biological chemistry

Telomerase-independent regulation of ATR by human telomerase RNA.

29-12-2006

Nature methods

shRNA libraries and their use in cancer genetics.

01-09-2006

Nature chemical biology

An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors.

01-04-2006

Cold Spring Harbor symposia on quantitative biology

Functional identification of cancer-relevant genes through large-scale RNA interference screens in mammalian cells.

25-08-2005

Cell

A genetic screen identifies PITX1 as a suppressor of RAS activity and tumorigenicity.

17-06-2005

Nature

A large-scale RNAi screen in human cells identifies new components of the p53 pathway.

25-03-2004

Genes & development

Degradation of E2F by the ubiquitin-proteasome pathway: regulation by retinoblastoma family proteins and adenovirus transforming proteins.

01-12-1996

Biochimica et biophysica acta

Cell cycle regulation by the retinoblastoma family of growth inhibitory proteins.

07-06-1996

The Journal of biological chemistry

Functional analysis of Burkitt's lymphoma mutant c-Myc proteins.

08-03-1996

Genes & development

Regulation of the retinoblastoma protein-related p107 by G1 cyclin complexes.

01-06-1995

Molecular and cellular biology

E2F-5, a new E2F family member that interacts with p130 in vivo.

01-06-1995

Genes & development

E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo.

15-11-1994

The EMBO journal

Interaction of c-Myc with the pRb-related protein p107 results in inhibition of c-Myc-mediated transactivation.

01-09-1994

The Journal of biological chemistry

Cell-cell adhesion mediated by a receptor-like protein tyrosine phosphatase.

05-08-1993

FEBS letters

Cloning, expression and chromosomal localization of a new putative receptor-like protein tyrosine phosphatase.

23-09-1991
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