Publications

The EMBO journal

Reconstitution of a surface transferrin binding complex in insect form Trypanosoma brucei.

01-06-1994

Cell

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs.

20-05-1994

Cell

Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins.

20-05-1994

Oncogene

Kras-2 alleles, mutations, and lung tumor susceptibility in the mouse--an evaluation.

01-05-1994

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Leukemia risk following Hodgkin's disease: relation to cumulative dose of alkylating agents, treatment with teniposide combinations, number of episodes of chemotherapy, and bone marrow damage.

01-05-1994

Virology

Mutagenesis and characterization of a 41-kilobase-pair region of the pseudorabies virus genome: transcription map, search for virulence genes, and comparison with homologs of herpes simplex virus type 1.

01-05-1994

European journal of immunology

Targeting major histocompatibility complex class II molecules to the cell surface by invariant chain allows antigen presentation upon recycling.

01-04-1994

Experimental cell research

The alpha 6 beta 4 integrin is a receptor for both laminin and kalinin.

01-04-1994

Genes & development

Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene.

01-04-1994

European journal of immunology

CD3 components at the surface of pro-T cells can mediate pre-T cell development in vivo.

01-04-1994

Lancet (London, England)

Risk of endometrial cancer after tamoxifen treatment of breast cancer.

19-02-1994

The Journal of biological chemistry

cAMP abrogates the p21ras-mitogen-activated protein kinase pathway in fibroblasts.

04-02-1994

Molecular biology of the cell

Distinct and overlapping ligand specificities of the alpha 3A beta 1 and alpha 6A beta 1 integrins: recognition of laminin isoforms.

01-02-1994

Annals of oncology : official journal of the European Society for Medical Oncology

Toxicity grading systems. A comparison between the WHO scoring system and the Common Toxicity Criteria when used for nausea and vomiting.

01-02-1994

Radiation research

Ionizing radiation enhances platelet adhesion to the extracellular matrix of human endothelial cells by an increase in the release of von Willebrand factor.

01-02-1994

Annals of oncology : official journal of the European Society for Medical Oncology

Intraperitoneal-administered carboplatin in patients with ovarian cancer; influence of a dwell-time on toxicity and response.

01-02-1994

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Second cancer risk following Hodgkin's disease: a 20-year follow-up study.

01-02-1994

Annals of oncology : official journal of the European Society for Medical Oncology

The quality of life of long-term survivors of Hodgkin's disease.

01-02-1994

Journal of cell science

Expression of the integrin alpha 6 beta 4 in peripheral nerves: localization in Schwann and perineural cells and different variants of the beta 4 subunit.

01-02-1994

Journal of chromatography

Fully automated high-performance liquid chromatographic method for the determination of carzelesin (U-80,244) and metabolites (U-76,073 and U-76,074) in human plasma.

14-01-1994

Cancer chemotherapy and pharmacology

Pharmaceutical development of a parenteral lyophilized formulation of the novel indoloquinone antitumor agent EO9.

01-01-1994

Cold Spring Harbor symposia on quantitative biology

Mouse model systems to study multistep tumorigenesis.

01-01-1994

Cancer chemotherapy and pharmacology

The pharmacokinetics of reduced folates after intraperitoneal and intravenous administration of racemic [6S,R]-folinic acid.

01-01-1994

Annals of oncology : official journal of the European Society for Medical Oncology

Etoposide, leucovorin, 5-fluorouracil (ELF) combination chemotherapy for advanced gastric cancer: experience with two treatment schedules incorporating intravenous or oral etoposide.

01-01-1994

Cancer chemotherapy and pharmacology

Lithium pharmacokinetics during cisplatin-based chemotherapy: a case report.

01-01-1994

Investigational new drugs

Pharmaceutical development of a parenteral formulation of the novel anti-tumor agent carzelesin (U-80,244).

01-01-1994

Cancer chemotherapy and pharmacology

Plasma pharmacokinetics, tissue disposition, excretion and metabolism of vinleucinol in mice as determined by high-performance liquid chromatography.

01-01-1994

Cancer chemotherapy and pharmacology

Validation of a limited sampling model for carboplatin in a high-dose chemotherapy combination.

01-01-1994

Pharmacy world & science : PWS

Signal transduction pathways: new targets in oncology.

17-12-1993

Cell

beta-D-glucosyl-hydroxymethyluracil: a novel modified base present in the DNA of the parasitic protozoan T. brucei.

17-12-1993

The Journal of biological chemistry

Expression and function of the cytoplasmic variants of the integrin alpha 6 subunit in transfected K562 cells. Activation-dependent adhesion and interaction with isoforms of laminin.

05-12-1993

Journal of cell science

Formation of hemidesmosomes in cells of a transformed murine mammary tumor cell line and mechanisms involved in adherence of these cells to laminin and kalinin.

01-12-1993

Cell

Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease.

05-11-1993

The Annals of otology, rhinology, and laryngology

Improvements in respiratory and psychosocial functioning following total laryngectomy by the use of a heat and moisture exchanger.

01-11-1993

The Journal of experimental medicine

Pim-1 levels determine the size of early B lymphoid compartments in bone marrow.

01-11-1993

Journal of pharmaceutical and biomedical analysis

Chemical stability of the new antitumour agent intoplicine in infusion fluids.

01-11-1993

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Pharmacokinetics of paclitaxel and metabolites in a randomized comparative study in platinum-pretreated ovarian cancer patients.

01-11-1993

Pharmacology & therapeutics

Classical and novel forms of multidrug resistance and the physiological functions of P-glycoproteins in mammals.

01-11-1993

Nucleic acids research

In vivo analysis of Pim-1 deficiency.

11-10-1993

Human molecular genetics

Characterization and chromosomal localization of the human proto-oncogene BMI-1.

01-10-1993

International journal of cancer

Binding properties of monoclonal antibodies recognizing external epitopes of the human MDR1 P-glycoprotein.

30-09-1993

The Journal of biological chemistry

The role of phosphorylation in activation of the alpha 6A beta 1 laminin receptor.

05-09-1993

Anticancer research

Clinical pharmacokinetics and pharmacodynamics of anticancer agents in pediatric patients (review).

01-09-1993

Blood

Impaired interleukin-3 response in Pim-1-deficient bone marrow-derived mast cells.

01-09-1993

Proceedings of the National Academy of Sciences of the United States of America

Target-selected gene inactivation in Caenorhabditis elegans by using a frozen transposon insertion mutant bank.

15-08-1993

The Journal of biological chemistry

Cell-cell adhesion mediated by a receptor-like protein tyrosine phosphatase.

05-08-1993

Leukemia

Analysis of Pim-1 function in mutant mice.

01-08-1993

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

The European Organization for Research and Treatment of Cancer. Approach to quality of life assessment: guidelines for developing questionnaire modules. EORTC Study Group on Quality of Life.

01-08-1993

Journal of parenteral science and technology : a publication of the Parenteral Drug Association

Chemical stability of the cardioprotective agent ICRF-187 in infusion fluids.

01-07-1993

Blood

Evidence for small intracellular vesicles in human blood phagocytes containing cytochrome b558 and the adhesion molecule CD11b/CD18.

01-06-1993