Banner Publications MH200828 N141

Publications

Results found: 220

Showing results: 1 - 50

Bioinformatics (Oxford, England)

Comparative Network Reconstruction using mixed integer programming.

01-09-2018
Key
Life science alliance

Genetic and compound screens uncover factors modulating cancer cell response to indisulam.

01-09-2022
Nature communications

DNA damage-induced transcription stress triggers the genome-wide degradation of promoter-bound Pol II.

24-06-2022
NPJ breast cancer

Allelic expression imbalance of PIK3CA mutations is frequent in breast cancer and prognostically significant.

08-06-2022
Nature reviews. Cancer

Exploiting senescence for the treatment of cancer.

01-06-2022
Genome medicine

Targeting CDC7 potentiates ATR-CHK1 signaling inhibition through induction of DNA replication stress in liver cancer.

18-10-2021
Nature reviews. Gastroenterology & hepatology

Exploring liver cancer biology through functional genetic screens.

01-10-2021
Molecular cancer research : MCR

Identification of Autophagy-Related Genes as Targets for Senescence Induction Using a Customizable CRISPR-Based Suicide Switch Screen.

01-10-2021
Molecular oncology

Playing cancer at its own game: activating mitogenic signaling as a paradoxical intervention.

01-08-2021
Nature reviews. Clinical oncology

Precision oncology in metastatic colorectal cancer - from biology to medicine.

01-08-2021
Cell reports

The Cancer SENESCopedia: A delineation of cancer cell senescence.

27-07-2021
Nature cell biology

Publisher Correction: Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability.

01-07-2021
Nature

EGFR activation limits the response of liver cancer to lenvatinib.

01-07-2021
Nature cell biology

Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability.

01-06-2021
Cancer discovery

Thinking Differently about Cancer Treatment Regimens.

01-05-2021
The oncologist

Phase I Study of Afatinib and Selumetinib in Patients with KRAS-Mutated Colorectal, Non-Small Cell Lung, and Pancreatic Cancer.

01-04-2021
Cancers

Fighting Drug Resistance through the Targeting of Drug-Tolerant Persister Cells.

05-03-2021
Genome medicine

Correction to: A role for the unfolded protein response stress sensor ERN1 in regulating the response to MEK inhibitors in KRAS mutant colon cancers.

10-02-2021
British journal of cancer

Mutational profiles associated with resistance in patients with BRAFV600E mutant colorectal cancer treated with cetuximab and encorafenib +/- binimetinib or alpelisib.

01-01-2021
Cancer research

A Functional Genomic Screen Identifies the Deubiquitinase USP11 as a Novel Transcriptional Regulator of ERα in Breast Cancer.

15-11-2020
International journal of cancer

Investigating the concordance in molecular subtypes of primary colorectal tumors and their matched synchronous liver metastasis.

15-10-2020
eLife

A powerful drug combination strategy targeting glutamine addiction for the treatment of human liver cancer.

05-10-2020
Molecular oncology

Towards a cancer mission in Horizon Europe: recommendations.

01-08-2020
PloS one

Kinome capture sequencing of high-grade serous ovarian carcinoma reveals novel mutations in the JAK3 gene.

09-07-2020
Nature communications

Multiple low dose therapy as an effective strategy to treat EGFR inhibitor-resistant NSCLC tumours.

22-06-2020
Cancer chemotherapy and pharmacology

Phase I study of lapatinib plus trametinib in patients with KRAS-mutant colorectal, non-small cell lung, and pancreatic cancer.

01-05-2020
British journal of cancer

Phase 1 study of the pan-HER inhibitor dacomitinib plus the MEK1/2 inhibitor PD-0325901 in patients with KRAS-mutation-positive colorectal, non-small-cell lung and pancreatic cancer.

01-04-2020
Future oncology (London, England)

Vorinostat in patients with resistant BRAFV600E mutated advanced melanoma: a proof of concept study.

01-04-2020
Gut

CDK12 inhibition mediates DNA damage and is synergistic with sorafenib treatment in hepatocellular carcinoma.

01-04-2020
Future oncology (London, England)

Encorafenib, binimetinib and cetuximab combined therapy for patients with BRAFV600E mutant metastatic colorectal cancer.

01-02-2020
Translational oncology

RUNX2/CBFB modulates the response to MEK inhibitors through activation of receptor tyrosine kinases in KRAS-mutant colorectal cancer.

01-02-2020
Nature cancer

A roadmap for the next decade in cancer research.

01-01-2020
Clinical cancer research : an official journal of the American Association for Cancer Research

BET Inhibition as a Rational Therapeutic Strategy for Invasive Lobular Breast Cancer.

01-12-2019
Clinical cancer research : an official journal of the American Association for Cancer Research

Adaptive Resistance to Dual BRAF/MEK Inhibition in BRAF-Driven Tumors through Autocrine FGFR Pathway Activation.

01-12-2019
Clinical cancer research : an official journal of the American Association for Cancer Research

POSEIDON Trial Phase 1b Results: Safety, Efficacy and Circulating Tumor DNA Response of the Beta Isoform-Sparing PI3K Inhibitor Taselisib (GDC-0032) Combined with Tamoxifen in Hormone Receptor Positive Metastatic Breast Cancer Patients.

15-11-2019
Nature

Inducing and exploiting vulnerabilities for the treatment of liver cancer.

01-10-2019
Cancer letters

Low-dose triple drug combination targeting the PI3K/AKT/mTOR pathway and the MAPK pathway is an effective approach in ovarian clear cell carcinoma.

01-10-2019
The Journal of molecular diagnostics : JMD

MammaPrint and BluePrint Molecular Diagnostics Using Targeted RNA Next-Generation Sequencing Technology.

01-09-2019
Clinical cancer research : an official journal of the American Association for Cancer Research

EZH2 Is Overexpressed in BRCA1-like Breast Tumors and Predictive for Sensitivity to High-Dose Platinum-Based Chemotherapy.

15-07-2019
Nature cell biology

Mapping phospho-catalytic dependencies of therapy-resistant tumours reveals actionable vulnerabilities.

01-06-2019
Cancer research

PDLIM2 Is a Marker of Adhesion and β-Catenin Activity in Triple-Negative Breast Cancer.

15-05-2019
NPJ breast cancer

Estrogen receptor variants in ER-positive basal-type breast cancers responding to therapy like ER-negative breast cancers.

25-04-2019
Oncoimmunology

Assessment of PD-L1 expression across breast cancer molecular subtypes, in relation to mutation rate, BRCA1-like status, tumor-infiltrating immune cells and survival.

14-12-2018
Molecular & cellular oncology

With great power comes great vulnerability.

14-12-2018
Genome medicine

A role for the unfolded protein response stress sensor ERN1 in regulating the response to MEK inhibitors in KRAS mutant colon cancers.

27-11-2018
Journal of hepatology

Phospho-ERK is a biomarker of response to a synthetic lethal drug combination of sorafenib and MEK inhibition in liver cancer.

01-11-2018
Molecular & cellular proteomics : MCP

A System-wide Approach to Monitor Responses to Synergistic BRAF and EGFR Inhibition in Colorectal Cancer Cells.

01-10-2018
Trends in molecular medicine

An Experimenter's Guide to Glioblastoma Invasion Pathways.

01-09-2018
The Journal of clinical investigation

Neuropilin-1 upregulation elicits adaptive resistance to oncogene-targeted therapies.

31-08-2018
Clinical cancer research : an official journal of the American Association for Cancer Research

Integrative Kinome Profiling Identifies mTORC1/2 Inhibition as Treatment Strategy in Ovarian Clear Cell Carcinoma.

15-08-2018

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