Publications

Molecular cell

Freedom to err: The expanding cellular functions of translesion DNA polymerases.

19-10-2023

Bio-protocol

Quantification of Chromosomal Aberrations in Mammalian Cells.

20-08-2023

Molecular & cellular proteomics : MCP

Ubiquitinome Profiling Reveals in Vivo UBE2D3 Targets and Implicates UBE2D3 in Protein Quality Control.

01-06-2023

Journal of lipid research

Role of enterocyte Enpp2 and autotaxin in regulating lipopolysaccharide levels, systemic inflammation, and atherosclerosis.

01-05-2023

Nature communications

MAD2L2 promotes replication fork protection and recovery in a shieldin-independent and REV3L-dependent manner.

08-09-2022

Nature communications

MAD2L2 dimerization and TRIP13 control shieldin activity in DNA repair.

14-09-2021

Trends in cell biology

REV7: Jack of many trades.

01-08-2021

Oncogene

H3K36 dimethylation by MMSET promotes classical non-homologous end-joining at unprotected telomeres.

01-06-2020

Nature cell biology

Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells.

01-08-2018

Cell reports

The CST Complex Mediates End Protection at Double-Strand Breaks and Promotes PARP Inhibitor Sensitivity in BRCA1-Deficient Cells.

15-05-2018

Cell cycle (Georgetown, Tex.)

H4K20me2 distinguishes pre-replicative from post-replicative chromatin to appropriately direct DNA repair pathway choice by 53BP1-RIF1-MAD2L2.

22-11-2017

Ubiquitination and SUMOylation in Telomere Maintenance and Dysfunction

23-05-2017

Clinical cancer research : an official journal of the American Association for Cancer Research

Effective Clinical Responses in Metastatic Melanoma Patients after Vaccination with Primary Myeloid Dendritic Cells.

01-05-2016

Molecular cell

PARP1 Links CHD2-Mediated Chromatin Expansion and H3.3 Deposition to DNA Repair by Non-homologous End-Joining.

18-02-2016

Nature

MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection.

28-05-2015

Frontiers in oncology

Loss of telomere protection: consequences and opportunities.

19-04-2013

Nature reviews. Molecular cell biology

Senescence: back to telomeres.

01-04-2013

Nature reviews. Molecular cell biology

Senescence: back to telomeres.

01-04-2013

Cell cycle (Georgetown, Tex.)

Posttranslational control of telomere maintenance and the telomere damage response.

15-04-2012

Nucleus (Austin, Tex.)

Fusing telomeres with RNF8.

01-03-2012

Nature cell biology

DNA-damage response and repair activities at uncapped telomeres depend on RNF8.

21-08-2011

Oncogene

In vitro genetic screen identifies a cooperative role for LPA signaling and c-Myc in cell transformation.

20-11-2008

Cell cycle (Georgetown, Tex.)

p16INK4a as a second effector of the telomere damage pathway.

01-10-2005

Genes & development

Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice.

15-06-2005

The Journal of biological chemistry

The T-box repressors TBX2 and TBX3 specifically regulate the tumor suppressor gene p14ARF via a variant T-site in the initiator.

19-07-2002

Biochimica et biophysica acta

Polycomb repression: from cellular memory to cellular proliferation and cancer.

21-06-2002

Nature genetics

Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers.

01-11-2000

Genes & development

Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF.

15-10-1999

Seminars in cell & developmental biology

Cellular memory of transcriptional states by Polycomb-group proteins.

01-04-1999

Nature

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus.

14-01-1999

Journal of molecular biology

MPc2, a new murine homolog of the Drosophila polycomb protein is a member of the mouse polycomb transcriptional repressor complex.

14-11-1997

A single amino acid exchange, Arg-45 to Ala, generates an epidermal growth factor (EGF) mutant with high affinity for the chicken EGF receptor

Specific expression in mouse mesoderm- and neural crest-derived tissues of a human PDGFRA promoter/lacZ transgene