Publications

The Journal of endocrinology

The first decade of estrogen receptor cistromics in breast cancer.

01-05-2016

Genomics data

Androgen receptor DNA binding and chromatin accessibility profiling in prostate cancer.

01-03-2016

Nature biotechnology

Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9.

01-02-2016

Clinical cancer research : an official journal of the American Association for Cancer Research

SRC3 Phosphorylation at Serine 543 Is a Positive Independent Prognostic Factor in ER-Positive Breast Cancer.

15-01-2016

EMBO molecular medicine

Androgen receptor profiling predicts prostate cancer outcome.

01-11-2015

Cell reports

APOBEC3B-Mediated Cytidine Deamination Is Required for Estrogen Receptor Action in Breast Cancer.

06-10-2015

Nature reviews. Clinical oncology

Cognitive effects of endocrine therapy for breast cancer: keep calm and carry on?

01-10-2015

BMC cancer

Protein Kinase A-induced tamoxifen resistance is mediated by anchoring protein AKAP13.

14-08-2015

Clinical pharmacokinetics

Effects of Pharmacogenetics on the Pharmacokinetics and Pharmacodynamics of Tamoxifen.

01-08-2015

Genomics data

Genome-wide epigenetic profiling of breast cancer tumors treated with aromatase inhibitors.

01-12-2014

Cancer research

Complex formation and function of estrogen receptor α in transcription requires RIP140.

01-10-2014

Cancer research

USP9X downregulation renders breast cancer cells resistant to tamoxifen.

15-07-2014

Nucleic acids research

Co-regulated gene expression by oestrogen receptor α and liver receptor homolog-1 is a feature of the oestrogen response in breast cancer cells.

01-12-2013

Cancer research

Hallmarks of aromatase inhibitor drug resistance revealed by epigenetic profiling in breast cancer.

15-11-2013

European journal of pharmacology

Tamoxifen resistance: from bench to bedside.

05-10-2013

Breast cancer research and treatment

Estrogen receptor splice variants as a potential source of false-positive estrogen receptor status in breast cancer diagnostics.

01-08-2013

Oncogene

PKA phosphorylation redirects ERα to promoters of a unique gene set to induce tamoxifen resistance.

25-07-2013

Nature communications

Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin.

30-05-2013

Proceedings of the National Academy of Sciences of the United States of America

Identification of a pharmacologically tractable Fra-1/ADORA2B axis promoting breast cancer metastasis.

26-03-2013

Nature reviews. Clinical oncology

Can predictive biomarkers in breast cancer guide adjuvant endocrine therapy?

01-09-2012

The EMBO journal

Oestrogen receptor-co-factor-chromatin specificity in the transcriptional regulation of breast cancer.

14-10-2011

Breast cancer research and treatment

PKA-induced phosphorylation of ERα at serine 305 and high PAK1 levels is associated with sensitivity to tamoxifen in ER-positive breast cancer.

01-01-2011

Journal of cell science

The invariant chain transports TNF family member CD70 to MHC class II compartments in dendritic cells.

01-11-2010

Nature cell biology

A Pumilio-induced RNA structure switch in p27-3' UTR controls miR-221 and miR-222 accessibility.

01-10-2010

Journal of cell science

The hinge region of the human estrogen receptor determines functional synergy between AF-1 and AF-2 in the quantitative response to estradiol and tamoxifen.

15-04-2010

Molecular endocrinology (Baltimore, Md.)

Resistance to antiestrogen arzoxifene is mediated by overexpression of cyclin D1.

01-09-2009

The Journal of cell biology

Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7-RILP-p150 Glued and late endosome positioning.

29-06-2009

The EMBO journal

PKA-induced resistance to tamoxifen is associated with an altered orientation of ERalpha towards co-activator SRC-1.

08-08-2007

Molecular cancer therapeutics

Classification of anti-estrogens according to intramolecular FRET effects on phospho-mutants of estrogen receptor alpha.

01-05-2007

Nuclear receptor signaling

Visualizing the action of steroid hormone receptors in living cells.

09-03-2007

Current opinion in microbiology

Presenting antigen presentation in living cells using biophysical techniques.

01-06-2005

The first decade of estrogen receptor cistromics in breast cancer.

Androgen receptor DNA binding and chromatin accessibility profiling in prostate cancer.

Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9.

SRC3 Phosphorylation at Serine 543 Is a Positive Independent Prognostic Factor in ER-Positive Breast Cancer.

Androgen receptor profiling predicts prostate cancer outcome.

APOBEC3B-Mediated Cytidine Deamination Is Required for Estrogen Receptor Action in Breast Cancer.

Cognitive effects of endocrine therapy for breast cancer: keep calm and carry on?

Protein Kinase A-induced tamoxifen resistance is mediated by anchoring protein AKAP13.

Effects of Pharmacogenetics on the Pharmacokinetics and Pharmacodynamics of Tamoxifen.

Genome-wide epigenetic profiling of breast cancer tumors treated with aromatase inhibitors.

Complex formation and function of estrogen receptor α in transcription requires RIP140.

USP9X downregulation renders breast cancer cells resistant to tamoxifen.

Co-regulated gene expression by oestrogen receptor α and liver receptor homolog-1 is a feature of the oestrogen response in breast cancer cells.

Hallmarks of aromatase inhibitor drug resistance revealed by epigenetic profiling in breast cancer.

Tamoxifen resistance: from bench to bedside.

Estrogen receptor splice variants as a potential source of false-positive estrogen receptor status in breast cancer diagnostics.

PKA phosphorylation redirects ERα to promoters of a unique gene set to induce tamoxifen resistance.

Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin.

Identification of a pharmacologically tractable Fra-1/ADORA2B axis promoting breast cancer metastasis.

Can predictive biomarkers in breast cancer guide adjuvant endocrine therapy?

Oestrogen receptor-co-factor-chromatin specificity in the transcriptional regulation of breast cancer.

PKA-induced phosphorylation of ERα at serine 305 and high PAK1 levels is associated with sensitivity to tamoxifen in ER-positive breast cancer.

The invariant chain transports TNF family member CD70 to MHC class II compartments in dendritic cells.

A Pumilio-induced RNA structure switch in p27-3' UTR controls miR-221 and miR-222 accessibility.

The hinge region of the human estrogen receptor determines functional synergy between AF-1 and AF-2 in the quantitative response to estradiol and tamoxifen.

Resistance to antiestrogen arzoxifene is mediated by overexpression of cyclin D1.

Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7-RILP-p150 Glued and late endosome positioning.

PKA-induced resistance to tamoxifen is associated with an altered orientation of ERalpha towards co-activator SRC-1.

Classification of anti-estrogens according to intramolecular FRET effects on phospho-mutants of estrogen receptor alpha.

Visualizing the action of steroid hormone receptors in living cells.

Presenting antigen presentation in living cells using biophysical techniques.

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