Publications

Nature reviews. Molecular cell biology

Seeing transcription in real time.

05-04-2024

Molecular cell

Transcription factor exchange enables prolonged transcriptional bursts.

21-03-2024

Trends in genetics : TIG

Time will tell: comparing timescales to gain insight into transcriptional bursting.

01-02-2024

Molecular cell

Locus-specific proteome decoding reveals Fpt1 as a chromatin-associated negative regulator of RNA polymerase III assembly.

07-12-2023

Methods in molecular biology (Clifton, N.J.)

Measuring Transcription Dynamics of Individual Genes Inside Living Cells.

12-10-2023

Research square

Competition between transcription and loop extrusion modulates promoter and enhancer dynamics.

16-08-2023

Nucleic acids research

Transcription factor clusters enable target search but do not contribute to target gene activation.

23-06-2023

Molecular cell

DNA supercoiling restricts the transcriptional bursting of neighboring eukaryotic genes.

18-05-2023

Nature structural & molecular biology

Dynamic epistasis analysis reveals how chromatin remodeling regulates transcriptional bursting.

01-05-2023

bioRxiv : the preprint server for biology

Competition between transcription and loop extrusion modulates promoter and enhancer dynamics.

26-04-2023

eLife

Quantifying how post-transcriptional noise and gene copy number variation bias transcriptional parameter inference from mRNA distributions.

17-10-2022

Genes & development

Transcriptional regulation and chromatin architecture maintenance are decoupled functions at the Sox2 locus.

01-06-2022

Biophysical journal

Following the tracks: How transcription factor binding dynamics control transcription.

03-05-2022

Nucleic acids research

Transcription-replication coordination revealed in single live cells.

28-02-2022

The EMBO journal

The Hda1 histone deacetylase limits divergent non-coding transcription and restricts transcription initiation frequency.

01-12-2021

STAR protocols

Optimized protocol for single-molecule RNA FISH to visualize gene expression in S. cerevisiae.

17-09-2021

STAR protocols

Single-Molecule Fluorescence Imaging in Living Saccharomyces cerevisiae Cells.

18-12-2020

Molecular cell

RNA Pol II Length and Disorder Enable Cooperative Scaling of Transcriptional Bursting.

16-07-2020

Current opinion in chemical biology

Visualizing transcription: key to understanding gene expression dynamics.

01-08-2019

The EMBO journal

Live-cell imaging reveals the interplay between transcription factors, nucleosomes, and bursting.

17-06-2019

Nucleic acids research

Dot1 promotes H2B ubiquitination by a methyltransferase-independent mechanism.

30-11-2018

PLoS genetics

A barcode screen for epigenetic regulators reveals a role for the NuB4/HAT-B histone acetyltransferase complex in histone turnover.

01-10-2011

Epigenetics & chromatin

Dot1 binding induces chromatin rearrangements by histone methylation-dependent and -independent mechanisms.

03-02-2011