Publications

Molecular oncology

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD-L1 in melanoma.

01-05-2026

Nature communications

Mapping functional non-coding variation in individual human genomes through haplotyping, multiomics, and deep learning.

29-04-2026

Nature

Regulatory grammar in human promoters uncovered by MPRA-based deep learning.

01-03-2026

Communications biology

PRC2 loss impairs small cell lung cancer tumorigenesis and enhances sensitivity to G9a/GLP inhibition.

21-02-2026

RSC chemical biology

Identification of mono-ADP-ribose readers using well-defined photoaffinity-based probes.

11-02-2026

Nature communications

Meta-unstable mRNAs in activated CD8⁺ T cells are defined by interlinked AU-rich elements and m⁶A mRNA methylation.

22-01-2026

bioRxiv : the preprint server for biology

Functional characterization of a multi-cancer risk locus on chromosome band 2q33.1 near CASP8.

06-01-2026

Molecular cell

Cell-surface RNA forms ternary complex with RNA-binding proteins and heparan sulfate to recruit immune receptors.

18-12-2025

The Lancet. Oncology

Pembrolizumab plus lenvatinib as second-line treatment in patients with pleural mesothelioma (PEMMELA): cohort 2 of a single-arm, phase 2 study.

01-12-2025

The EMBO journal

Auto-inhibition of PRC2 by the broadly expressed long isoform of AEBP2.

01-12-2025

Immunity

Cryo-EM structure of endogenous Pfs230:Pfs48/45 complex with six antibodies reveals mechanisms of malaria transmission-blocking activity.

11-11-2025

Nucleic acids research

DNA polymerase kappa is the primary translesion synthesis polymerase for aldehyde ICLs.

23-09-2025

Molecular & cellular proteomics : MCP

Proteome and Secretome Profiling of the Melanoma-Induced Transition Toward Immune Incompetent Dendritic Cells Reveals Enhanced IDO1, Cathepsin, and Legumain Activity.

01-09-2025

JTO clinical and research reports

Longitudinal Circulating Tumor DNA-Guided Resistance Analysis During Second-Line Osimertinib Treatment.

01-09-2025

Science (New York, N.Y.)

Zincore, an atypical coregulator, binds zinc finger transcription factors to control gene expression.

03-07-2025

bioRxiv : the preprint server for biology

Structure of endogenous Pfs230:Pfs48/45 in complex with potent malaria transmission-blocking antibodies.

15-06-2025

Molecular cell

A specific form of cPRC1 containing CBX4 is co-opted to mediate oncogenic gene repression in diffuse midline glioma.

05-06-2025

Cellular and molecular life sciences : CMLS

CD151 interacts with integrin beta 2 in B cell lymphomas.

04-06-2025

Genome biology

Endometrial tumorigenesis involves epigenetic plasticity demarcating non-coding somatic mutations and 3D-genome alterations.

09-05-2025

Cell death and differentiation

UGT8 mediated sulfatide synthesis modulates BAX localization and dictates apoptosis sensitivity of colorectal cancer.

01-04-2025

American journal of physiology. Renal physiology

Proteomic analysis of urinary extracellular vesicles from patients with ADTKD-HNF1β identifies roles for cilia-related proteins and serpins.

01-04-2025

Cell reports

PRC1 and PRC2 proximal interactome in mouse embryonic stem cells.

25-03-2025

Chembiochem : a European journal of chemical biology

Proteome-Wide Profiling of Olaparib Interactors Using a Biotinylated Photoaffinity Probe.

15-03-2025

Nucleic acids research

The farnesoid X receptor activates transcription independently of RXR at non-canonical response elements.

08-02-2025

Biochimica et biophysica acta. Biomembranes

Identification of a sorting motif for Tspan3 to MHCII compartments in human B cells.

01-02-2025

Cell reports

A conserved switch to less catalytically active Polycomb repressive complexes in non-dividing cells.

28-01-2025

Genome research

Characterization of DNA methylation reader proteins in Arabidopsis thaliana.

23-12-2024

Nature protocols

Quantifying genome-wide transcription factor binding affinities for chromatin using BANC-seq.

01-12-2024

Lung cancer (Amsterdam, Netherlands)

Combined analysis of circulating tumor DNA and tumor tissue to overcome osimertinib resistance (OSIRIS); the second line osimertinib cohort.

01-12-2024

Trends in biochemical sciences

The quest to identify ADP-ribosylation readers: methodological advances.

01-11-2024

Nature communications

The small CRL4^CSA ubiquitin ligase component DDA1 regulates transcription-coupled repair dynamics.

29-07-2024

Cell stem cell

Deciphering lineage specification during early embryogenesis in mouse gastruloids using multilayered proteomics.

05-07-2024

Genome research

Estrogen receptor 1 chromatin profiling in human breast tumors reveals high inter-patient heterogeneity with enrichment of risk SNPs and enhancer activity at most-conserved regions.

15-05-2024

Nature

Publisher Correction: Decoding chromatin states by proteomic profiling of nucleosome readers.

01-04-2024

Communications biology

GFI1B and LSD1 repress myeloid traits during megakaryocyte differentiation.

28-03-2024

Nature

Decoding chromatin states by proteomic profiling of nucleosome readers.

01-03-2024

Nature genetics

A chromatin-regulated biphasic circuit coordinates IL-1β-mediated inflammation.

01-01-2024

The Journal of pathology

Transcriptomics and proteomics reveal distinct biology for lymph node metastases and tumour deposits in colorectal cancer.

01-12-2023

Nature biotechnology

Quantification of absolute transcription factor binding affinities in the native chromatin context using BANC-seq.

01-12-2023

Journal of visualized experiments : JoVE

Gut Isolation from Zebrafish Larvae for Single-cell RNA Sequencing.

10-11-2023

The Lancet. Oncology

Pembrolizumab plus lenvatinib in second-line and third-line patients with pleural mesothelioma (PEMMELA): a single-arm phase 2 study.

01-11-2023

The Journal of biological chemistry

STPP-UP: An alternative method for drug target identification using protein thermal stability.

01-11-2023

Research square

DDA1, a novel factor in transcription-coupled repair, modulates CRL4^CSA dynamics at DNA damage-stalled RNA polymerase II.

12-10-2023

DNA repair

Live cell transcription-coupled nucleotide excision repair dynamics revisited.

01-10-2023

Cellular and molecular life sciences : CMLS

Galectin-9 interacts with Vamp-3 to regulate cytokine secretion in dendritic cells.

27-09-2023

Journal of proteome research

Determining DNA-Protein Binding Affinities and Specificities from Crude Lysates Using a Combined SILAC/TMT Labeling Strategy.

04-08-2023

Thyroid research

Determinants and mediating mechanisms of quality of life and disease-specific symptoms among thyroid cancer patients: the design of the WaTCh study.

10-07-2023

Nature communications

THRONCAT: metabolic labeling of newly synthesized proteins using a bioorthogonal threonine analog.

08-06-2023

Molecular cell

PRC2.1- and PRC2.2-specific accessory proteins drive recruitment of different forms of canonical PRC1.

04-05-2023

Cell reports. Medicine

Genetic screens reveal new targetable vulnerabilities in BAP1-deficient mesothelioma.

21-02-2023

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD-L1 in melanoma.

Mapping functional non-coding variation in individual human genomes through haplotyping, multiomics, and deep learning.

Regulatory grammar in human promoters uncovered by MPRA-based deep learning.

PRC2 loss impairs small cell lung cancer tumorigenesis and enhances sensitivity to G9a/GLP inhibition.

Identification of mono-ADP-ribose readers using well-defined photoaffinity-based probes.

Meta-unstable mRNAs in activated CD8+ T cells are defined by interlinked AU-rich elements and m6A mRNA methylation.

Functional characterization of a multi-cancer risk locus on chromosome band 2q33.1 near CASP8.

Cell-surface RNA forms ternary complex with RNA-binding proteins and heparan sulfate to recruit immune receptors.

Pembrolizumab plus lenvatinib as second-line treatment in patients with pleural mesothelioma (PEMMELA): cohort 2 of a single-arm, phase 2 study.

Auto-inhibition of PRC2 by the broadly expressed long isoform of AEBP2.

Cryo-EM structure of endogenous Pfs230:Pfs48/45 complex with six antibodies reveals mechanisms of malaria transmission-blocking activity.

DNA polymerase kappa is the primary translesion synthesis polymerase for aldehyde ICLs.

Proteome and Secretome Profiling of the Melanoma-Induced Transition Toward Immune Incompetent Dendritic Cells Reveals Enhanced IDO1, Cathepsin, and Legumain Activity.

Longitudinal Circulating Tumor DNA-Guided Resistance Analysis During Second-Line Osimertinib Treatment.

Zincore, an atypical coregulator, binds zinc finger transcription factors to control gene expression.

Structure of endogenous Pfs230:Pfs48/45 in complex with potent malaria transmission-blocking antibodies.

A specific form of cPRC1 containing CBX4 is co-opted to mediate oncogenic gene repression in diffuse midline glioma.

CD151 interacts with integrin beta 2 in B cell lymphomas.

Endometrial tumorigenesis involves epigenetic plasticity demarcating non-coding somatic mutations and 3D-genome alterations.

UGT8 mediated sulfatide synthesis modulates BAX localization and dictates apoptosis sensitivity of colorectal cancer.

Proteomic analysis of urinary extracellular vesicles from patients with ADTKD-HNF1β identifies roles for cilia-related proteins and serpins.

PRC1 and PRC2 proximal interactome in mouse embryonic stem cells.

Proteome-Wide Profiling of Olaparib Interactors Using a Biotinylated Photoaffinity Probe.

The farnesoid X receptor activates transcription independently of RXR at non-canonical response elements.

Identification of a sorting motif for Tspan3 to MHCII compartments in human B cells.

A conserved switch to less catalytically active Polycomb repressive complexes in non-dividing cells.

Characterization of DNA methylation reader proteins in Arabidopsis thaliana.

Quantifying genome-wide transcription factor binding affinities for chromatin using BANC-seq.

Combined analysis of circulating tumor DNA and tumor tissue to overcome osimertinib resistance (OSIRIS); the second line osimertinib cohort.

The quest to identify ADP-ribosylation readers: methodological advances.

The small CRL4CSA ubiquitin ligase component DDA1 regulates transcription-coupled repair dynamics.

Deciphering lineage specification during early embryogenesis in mouse gastruloids using multilayered proteomics.

Estrogen receptor 1 chromatin profiling in human breast tumors reveals high inter-patient heterogeneity with enrichment of risk SNPs and enhancer activity at most-conserved regions.

Publisher Correction: Decoding chromatin states by proteomic profiling of nucleosome readers.

GFI1B and LSD1 repress myeloid traits during megakaryocyte differentiation.

Decoding chromatin states by proteomic profiling of nucleosome readers.

A chromatin-regulated biphasic circuit coordinates IL-1β-mediated inflammation.

Transcriptomics and proteomics reveal distinct biology for lymph node metastases and tumour deposits in colorectal cancer.

Quantification of absolute transcription factor binding affinities in the native chromatin context using BANC-seq.

Gut Isolation from Zebrafish Larvae for Single-cell RNA Sequencing.

Pembrolizumab plus lenvatinib in second-line and third-line patients with pleural mesothelioma (PEMMELA): a single-arm phase 2 study.

STPP-UP: An alternative method for drug target identification using protein thermal stability.

DDA1, a novel factor in transcription-coupled repair, modulates CRL4CSA dynamics at DNA damage-stalled RNA polymerase II.

Live cell transcription-coupled nucleotide excision repair dynamics revisited.

Galectin-9 interacts with Vamp-3 to regulate cytokine secretion in dendritic cells.

Determining DNA-Protein Binding Affinities and Specificities from Crude Lysates Using a Combined SILAC/TMT Labeling Strategy.

Determinants and mediating mechanisms of quality of life and disease-specific symptoms among thyroid cancer patients: the design of the WaTCh study.

THRONCAT: metabolic labeling of newly synthesized proteins using a bioorthogonal threonine analog.

PRC2.1- and PRC2.2-specific accessory proteins drive recruitment of different forms of canonical PRC1.

Genetic screens reveal new targetable vulnerabilities in BAP1-deficient mesothelioma.

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Meta-unstable mRNAs in activated CD8⁺ T cells are defined by interlinked AU-rich elements and m⁶A mRNA methylation.

The small CRL4^CSA ubiquitin ligase component DDA1 regulates transcription-coupled repair dynamics.

DDA1, a novel factor in transcription-coupled repair, modulates CRL4^CSA dynamics at DNA damage-stalled RNA polymerase II.