Publications

Nature medicine

Glutaminyl cyclase is an enzymatic modifier of the CD47- SIRPα axis and a target for cancer immunotherapy.

01-04-2019

Nature communications

Barcoding reveals complex clonal behavior in patient-derived xenografts of metastatic triple negative breast cancer.

15-02-2019

PloS one

SLFN11 can sensitize tumor cells towards IFN-γ-mediated T cell killing.

13-02-2019

Cell

Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma.

07-02-2019

Nature medicine

Low and variable tumor reactivity of the intratumoral TCR repertoire in human cancers.

01-01-2019

Nature biotechnology

T cell receptor fingerprinting enables in-depth characterization of the interactions governing recognition of peptide-MHC complexes.

19-11-2018

Nature medicine

Neoadjuvant versus adjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma.

01-11-2018

Cell

Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids.

06-09-2018

Key Publication

ImmunoHorizons

Breadth and Dynamics of HLA-A2- and HLA-B7-Restricted CD8⁺ T Cell Responses against Nonstructural Viral Proteins in Acute Human Tick-Borne Encephalitis Virus Infection.

02-07-2018

Nature medicine

A transcriptionally and functionally distinct PD-1⁺ CD8⁺ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade.

01-07-2018

Cancer cell

T Cell Dysfunction in Cancer.

09-04-2018

Immunity

Regulation and Function of the PD-L1 Checkpoint.

20-03-2018

Cell

Antigen Identification for Orphan T Cell Receptors Expressed on Tumor-Infiltrating Lymphocytes.

25-01-2018

eLife

The Human Cell Atlas.

05-12-2017

JCO precision oncology

Profound Immunotherapy Response in Mismatch Repair-Deficient Breast Cancer.

01-11-2017

Nature biotechnology

Antigen receptor repertoire profiling from RNA-seq data.

11-10-2017

European journal of immunology

Guidelines for the use of flow cytometry and cell sorting in immunological studies.

01-10-2017

Nature

Identification of CMTM6 and CMTM4 as PD-L1 protein regulators.

07-09-2017

Cancer research

Acquired Immune Resistance Follows Complete Tumor Regression without Loss of Target Antigens or IFNγ Signaling.

01-09-2017

Cancer immunology, immunotherapy : CII

HPV16 E7 DNA tattooing: safety, immunogenicity, and clinical response in patients with HPV-positive vulvar intraepithelial neoplasia.

01-09-2017

Cancer research

T Cells Redirected to a Minor Histocompatibility Antigen Instruct Intratumoral TNFα Expression and Empower Adoptive Cell Therapy for Solid Tumors.

01-02-2017

JAMA oncology

Genomics- and Transcriptomics-Based Patient Selection for Cancer Treatment With Immune Checkpoint Inhibitors: A Review.

01-11-2016

Methods in molecular biology (Clifton, N.J.)

pMHC Multiplexing Strategy to Detect High Numbers of T Cell Responses in Parallel.

28-10-2016

The Journal of experimental medicine

Preventing tumor escape by targeting a post-proteasomal trimming independent epitope.

17-10-2016

The New England journal of medicine

Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma.

01-09-2016

Current opinion in immunology

Neoantigens encoded in the cancer genome.

01-08-2016

Current opinion in immunology

Editorial overview: Cancer immunology: genomics & biomarkers: Cancer immunity through the prism of genomics and proteomics.

01-08-2016

Cell reports

BRAF(V600E) Kinase Domain Duplication Identified in Therapy-Refractory Melanoma Patient-Derived Xenografts.

28-06-2016

Science (New York, N.Y.)

Targeting of cancer neoantigens with donor-derived T cell receptor repertoires.

10-06-2016

Annual review of immunology

T Cell Fate at the Single-Cell Level.

20-05-2016

Science (New York, N.Y.)

CANCER IMMUNOLOGY. The "cancer immunogram".

06-05-2016

BMC bioinformatics

Reproducibility of Illumina platform deep sequencing errors allows accurate determination of DNA barcodes in cells.

02-04-2016

Nature medicine

A liquid biopsy for cancer immunotherapy.

01-04-2016

Molecular therapy. Nucleic acids

A Traceless Selection: Counter-selection System That Allows Efficient Generation of Transposon and CRISPR-modified T-cell Products.

22-03-2016

Cell

The Branching Point in Erythro-Myeloid Differentiation.

17-12-2015

Journal of immunology (Baltimore, Md. : 1950)

Subtle CXCR3-Dependent Chemotaxis of CTLs within Infected Tissue Allows Efficient Target Localization.

01-12-2015

eLife

Bystander hyperactivation of preimmune CD8+ T cells in chronic HCV patients.

14-11-2015

Journal of immunology (Baltimore, Md. : 1950)

Definition of Proteasomal Peptide Splicing Rules for High-Efficiency Spliced Peptide Presentation by MHC Class I Molecules.

01-11-2015

Journal of immunology (Baltimore, Md. : 1950)

Peptide Splicing in the Proteasome Creates a Novel Type of Antigen with an Isopeptide Linkage.

01-11-2015

Molecular therapy : the journal of the American Society of Gene Therapy

Case Report of a Fatal Serious Adverse Event Upon Administration of T Cells Transduced With a MART-1-specific T-cell Receptor.

01-09-2015

EMBO molecular medicine

Intra- and inter-tumor heterogeneity in a vemurafenib-resistant melanoma patient and derived xenografts.

01-09-2015

Cancer cell

Mismatch Repair-Deficient Cancers Are Targets for Anti-PD-1 Therapy.

13-07-2015

Trends in immunology

Assessing T lymphocyte function and differentiation by genetically encoded reporter systems.

01-07-2015

Gene therapy

Antigen design enhances the immunogenicity of Semliki Forest virus-based therapeutic human papillomavirus vaccines.

01-07-2015

Science (New York, N.Y.)

Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer.

03-04-2015

Science (New York, N.Y.)

Neoantigens in cancer immunotherapy.

03-04-2015

Science translational medicine

Adoptive cellular therapy: a race to the finish line.

25-03-2015

Science (New York, N.Y.)

T cell immunity. Functional heterogeneity of human memory CD4⁺ T cell clones primed by pathogens or vaccines.

23-01-2015

Cancer cell

Biomarkers in cancer immunotherapy.

12-01-2015

Nature medicine

High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma.

01-01-2015

Glutaminyl cyclase is an enzymatic modifier of the CD47- SIRPα axis and a target for cancer immunotherapy.

Barcoding reveals complex clonal behavior in patient-derived xenografts of metastatic triple negative breast cancer.

SLFN11 can sensitize tumor cells towards IFN-γ-mediated T cell killing.

Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma.

Low and variable tumor reactivity of the intratumoral TCR repertoire in human cancers.

T cell receptor fingerprinting enables in-depth characterization of the interactions governing recognition of peptide-MHC complexes.

Neoadjuvant versus adjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma.

Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids.

Breadth and Dynamics of HLA-A2- and HLA-B7-Restricted CD8+ T Cell Responses against Nonstructural Viral Proteins in Acute Human Tick-Borne Encephalitis Virus Infection.

A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade.

T Cell Dysfunction in Cancer.

Regulation and Function of the PD-L1 Checkpoint.

Antigen Identification for Orphan T Cell Receptors Expressed on Tumor-Infiltrating Lymphocytes.

The Human Cell Atlas.

Profound Immunotherapy Response in Mismatch Repair-Deficient Breast Cancer.

Antigen receptor repertoire profiling from RNA-seq data.

Guidelines for the use of flow cytometry and cell sorting in immunological studies.

Identification of CMTM6 and CMTM4 as PD-L1 protein regulators.

Acquired Immune Resistance Follows Complete Tumor Regression without Loss of Target Antigens or IFNγ Signaling.

HPV16 E7 DNA tattooing: safety, immunogenicity, and clinical response in patients with HPV-positive vulvar intraepithelial neoplasia.

T Cells Redirected to a Minor Histocompatibility Antigen Instruct Intratumoral TNFα Expression and Empower Adoptive Cell Therapy for Solid Tumors.

Genomics- and Transcriptomics-Based Patient Selection for Cancer Treatment With Immune Checkpoint Inhibitors: A Review.

pMHC Multiplexing Strategy to Detect High Numbers of T Cell Responses in Parallel.

Preventing tumor escape by targeting a post-proteasomal trimming independent epitope.

Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma.

Neoantigens encoded in the cancer genome.

Editorial overview: Cancer immunology: genomics & biomarkers: Cancer immunity through the prism of genomics and proteomics.

BRAF(V600E) Kinase Domain Duplication Identified in Therapy-Refractory Melanoma Patient-Derived Xenografts.

Targeting of cancer neoantigens with donor-derived T cell receptor repertoires.

T Cell Fate at the Single-Cell Level.

CANCER IMMUNOLOGY. The "cancer immunogram".

Reproducibility of Illumina platform deep sequencing errors allows accurate determination of DNA barcodes in cells.

A liquid biopsy for cancer immunotherapy.

A Traceless Selection: Counter-selection System That Allows Efficient Generation of Transposon and CRISPR-modified T-cell Products.

The Branching Point in Erythro-Myeloid Differentiation.

Subtle CXCR3-Dependent Chemotaxis of CTLs within Infected Tissue Allows Efficient Target Localization.

Bystander hyperactivation of preimmune CD8+ T cells in chronic HCV patients.

Definition of Proteasomal Peptide Splicing Rules for High-Efficiency Spliced Peptide Presentation by MHC Class I Molecules.

Peptide Splicing in the Proteasome Creates a Novel Type of Antigen with an Isopeptide Linkage.

Case Report of a Fatal Serious Adverse Event Upon Administration of T Cells Transduced With a MART-1-specific T-cell Receptor.

Intra- and inter-tumor heterogeneity in a vemurafenib-resistant melanoma patient and derived xenografts.

Mismatch Repair-Deficient Cancers Are Targets for Anti-PD-1 Therapy.

Assessing T lymphocyte function and differentiation by genetically encoded reporter systems.

Antigen design enhances the immunogenicity of Semliki Forest virus-based therapeutic human papillomavirus vaccines.

Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer.

Neoantigens in cancer immunotherapy.

Adoptive cellular therapy: a race to the finish line.

T cell immunity. Functional heterogeneity of human memory CD4⁺ T cell clones primed by pathogens or vaccines.

Biomarkers in cancer immunotherapy.

High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma.

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Breadth and Dynamics of HLA-A2- and HLA-B7-Restricted CD8⁺ T Cell Responses against Nonstructural Viral Proteins in Acute Human Tick-Borne Encephalitis Virus Infection.

A transcriptionally and functionally distinct PD-1⁺ CD8⁺ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade.